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Testosterone Replacement Therapy (TRT) Treatment Options
A collection of 324 research studies where Testosterone Replacement Therapy (TRT) is the interventional treatment. These studies are located in the United States . Testosterone Replacement Therapy (TRT) is used for conditions such as .
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Featured Therapy
Unique Treatment for High Blood Pressure
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People who may be candidates for this procedure:
• Are at least 18 years old
• Have been unable to manage their high blood pressure with medications or lifestyle changes alone¹
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¹ Kandzari DE, et al. J Am Coll Cardiol. Nov 7, 2023;82(19):1809-1823.
People who may be candidates for this procedure:
• Are at least 18 years old
• Have been unable to manage their high blood pressure with medications or lifestyle changes alone¹
Learn about a safe and effective procedure that may help reduce high blood pressure. See if you qualify today.
¹ Kandzari DE, et al. J Am Coll Cardiol. Nov 7, 2023;82(19):1809-1823.
Conditions:
High Blood Pressure
High Blood Pressure (& [Essential Hypertension])
High Blood Pressure (Hypertension).
Hypertension
Essential Hypertension
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Conditions:
Healthy
Healthy Volunteer Study
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There's a big difference between the price on a landing page and what you actually pay. We went all the way through checkout so you know exactly what to expect.
📋 5 providers ranked by true monthly cost
💵 Options starting as low as $149/month
🏥 Only licensed providers using FDA-registered pharmacies
⭐ Real Trustpilot scores included — including the ones with mixed reviews
🔒 Includes cancellation policy warnings so you don't get stuck
Conditions:
Weight Loss
Morbid Obesity
Featured Trial
Healthy Participants Needed (Colonoscopy + Cancer Screening)
Recruiting
Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.
Conditions:
Healthy
Healthy Volunteers
Healthy Subjects
Healthy Volunteer
Healthy Participants
External Beam Radiation With or Without Chemotherapy to Treat High Risk Prostate Cancer
Terminated
The purpose of this study is to compare the effects on prostate cancer using radiation therapy with or without chemotherapy.
Gender:
MALE
Ages:
Between 18 years and 75 years
Trial Updated:
02/11/2016
Locations: CDH Proton Center, Warrenville, Illinois +2 locations
Conditions: Prostate Cancer
Oral Testosterone for the Treatment of Hypogonadism
Completed
Low testosterone is a condition that occurs when the body is unable to produce sufficient quantities of testosterone. The medical name for low testosterone is hypogonadism. Hypogonadism can be caused by many factors. Symptoms include: decrease in libido, lack of energy and mood swings. The goal of testosterone replacement therapy is to return testosterone levels to the normal range and relieve symptoms.
The purpose of this study is to evaluate the ability of TSX-002, which is testosterone provi... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
12/14/2015
Locations: Urology Group of Southern California, Los Angeles, California
Conditions: Hypogonadism
HOP-3 Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone
Completed
The purpose of this investigational study is to determine how much male hormone, testosterone, is necessary to maintain sperm production in the testis. This knowledge will be used to help in the development of a safe male hormonal contraception.
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
12/09/2015
Locations: University of Washington, Seattle, Washington
Conditions: Healthy Males
A Study in Men With Low Testosterone to Measure the Effects of Testosterone Solution on Testosterone Levels, Sex Drive and Energy
Completed
The main purpose of this study is to evaluate if testosterone solution can raise testosterone hormone levels into the normal range, and also improve levels of sexual arousal, interest and drive and/or energy level, in men with low testosterone and decreased sexual arousal, interest and drive and/or decreased energy. The study will last about 16 weeks, followed by an optional 24 week open label treatment phase to investigate the long term safety of testosterone solution.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/24/2015
Locations: For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Homewood, Alabama +84 locations
Conditions: Hypogonadism
Exogenous Testosterone Plus Dutasteride for the Treatment of Castrate Metastatic Prostate Cancer
Completed
Usually, the male hormone testosterone makes prostate cancer cells grow. Lowering testosterone usually stops the growth of prostate cancer. However, after a period of time without testosterone, prostate cancer cells learn to grow again.
You are able to join this trial because your prostate cancer is growing even though you have very low levels of testosterone. Studies have shown that high doses of testosterone, in this situation, can cause prostate cancer cells to stop growing.
The investigato... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/28/2015
Locations: Memorial Sloan-Kettering Cancer Center, New York, New York
Conditions: Prostate Cancer, Castration-resistant, Metastatic
The Effects of Long Term Cyclic Testosterone Administration on Muscle Function and Bone in Older Men
Withdrawn
The general hypothesis is that administration of testosterone to healthy, older men for 52 weeks (1 year) following a cycle of 4 weeks of testosterone administration and 4 weeks without testosterone (i.e., monthly cycled regimen) will provide the same gains in muscle strength, muscle mass, and bone density as standard of care (SOC), continuous administration of testosterone for 52 weeks.
Gender:
MALE
Ages:
Between 60 years and 75 years
Trial Updated:
09/30/2015
Locations: The University of Texas Medical Branch, Galveston, Galveston, Texas
Conditions: Sarcopenia
Cetuximab Plus Conformal Thoracic Radiotherapy in Patients (Pts) With Inoperable or Unresectable Locally Advanced Non-Small Cell Lung Cancer (LA - NSCLC)
Completed
This research is being done to find out if a treatment consisting of a combination of thoracic radiotherapy with cetuximab, given together, and followed by chemotherapy with docetaxel and cetuximab (also given together) will kill the cancer cells in the patient's body and shrink the size of their tumor without causing unacceptable side effects. This may allow patients to live longer or decrease the frequency and/or severity of the symptoms caused by the cancer without increasing the frequency an... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/23/2015
Locations: H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida
Conditions: Lung Cancer
The Effect on Androxal Versus Androgel on Morning Testosterone in Men With Secondary Hypogonadism (Low Testosterone)
Completed
The study will determine the effects of three doses of Androxal(enclomiphene citrate)on morning testosterone versus AndroGel(approved topical treatment)in men with low testosterone (\<350 ng/dL)after 6 weeks of continuous dosing.
Gender:
MALE
Ages:
Between 18 years and 65 years
Trial Updated:
08/21/2015
Locations: Centex Research, Houston, Texas +1 locations
Conditions: Secondary Hypogonadism
Effect of Testosterone Gel Replacement on Fat Mass in Males With Low Testosterone Levels and Diabetes
Withdrawn
The purpose of the study is to find out the effect of replacing testosterone in the form of a gel (Androgel®) on the amount of fat mass in males with low testosterone and diabetes.
Gender:
MALE
Ages:
Between 35 years and 75 years
Trial Updated:
08/06/2015
Locations: Diabetes Center of the Southwest, Midland, Texas
Conditions: Hypogonadism, Diabetes
To Evaluate Sperm Parameters in Men With Secondary Hypogonadism Previously Treated With Topical Testosterone
Completed
The study was designed to determine if Androxal® would affect sperm parameters (count, concentration, volume) in men with secondary hypogonadism who have been previously treated with topical testosterone.
Gender:
MALE
Ages:
Between 21 years and 60 years
Trial Updated:
07/22/2015
Locations: University Urology Associates, New York, New York +1 locations
Conditions: Secondary Hypogonadism
Testosterone for Penile Rehabilitation After Radical Prostatectomy
Terminated
The purpose of this study is to determine the effectiveness of testosterone replacement therapy (TRT) in men following surgery to remove the prostate in improving erectile function. Subjects will be randomized (like flipping a coin) to one of two groups. One group will receive Testim® (testosterone gel) 5 g per day plus Viagra 25 mg every night and the other will receive Placebo-Testim® 5 g per day plus Viagra 25 mg every night.
Subjects will begin drug treatment 3 months after the initial scre... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
06/02/2015
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Hypogonadism, Erectile Dysfunction
Testosterone and Pain Sensitivity
Withdrawn
This research is being done to see whether testosterone replacement in men who take opioid-based pain medications and have low testosterone levels will show improvement in pain tolerance, pain perception and quality of life.
Some men who take opioid-based medications (narcotics) for pain develop low testosterone levels. Research has shown that low testosterone levels may make a person more sensitive to pain. This means that if a person with a painful condition develops low testosterone level as... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/30/2015
Locations: Johns Hopkins Medical Institutions, Baltimore, Maryland
Conditions: Low Testosterone, Hypogonadism, Pain
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