Phase II Randomized Study of Physiologic Testosterone Replacement in Premenopausal, HIV-Positive Women
Completed
OBJECTIVES: I. Determine whether physiologic testosterone replacement can increase fat-free mass, therefore contributing to weight maintenance, improved muscle function, and quality of life in HIV-infected women. II. Examine the mechanism of testosterone-induced increase in fat-free mass.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
03/24/2015
Locations: Charles R. Drew University of Medicine and Science, Los Angeles, California +2 locations
Conditions: HIV Infections, Cachexia
Lybridos in Pre-and Postmenopausal Women With Hypoactive Sexual Desire Disorder
Completed
A double-blind, randomized, placebo-controlled, dose-finding study to investigate the safety and efficacy of Lybridos in the domestic setting in healthy female subjects with hypoactive sexual desire disorder and maladaptive activity of sexual inhibitory mechanisms. This is a 2-arm placebo and Lybridos (0.5 mg testosterone + buspirone 10 mg) extension to study EB90 (Clinical Study Protocol EB90a, version 3.0, 07 June 2013). In the present study, the efficacy of Lybridos will be evaluated in the... Read More
Gender:
FEMALE
Ages:
Between 21 years and 70 years
Trial Updated:
03/23/2015
Locations: San Diego Sexual Medicine, San Diego, California +9 locations
Conditions: Hypoactive Sexual Desire Disorder
Does Testosterone Improve Function in Hypogonadal Older Men
Withdrawn
This is a randomized controlled trial of testosterone replacement therapy in hypogonadal men age \> 60 years. The goal is to assess the safety and efficacy of TRT in men age \> 60 years.
Gender:
MALE
Ages:
Between 60 years and 80 years
Trial Updated:
02/12/2015
Locations: Nf/Sg Vhs, Gainesville, Florida
Conditions: Hypogonadism
Efficacy and Safety of Androgel in the Treatment of Hypogonadal and Low Testosterone Men With Type 2 Diabetes
Completed
This study is to investigate how well Androgel, when tested against placebo gel, helps to control blood sugar levels in males with type 2 diabetes who have low testosterone (the main male hormone) blood levels and are taking oral diabetic medicines alone or in combination with insulin.
Gender:
MALE
Ages:
Between 30 years and 80 years
Trial Updated:
01/19/2015
Locations: Site 58, Birmingham, Alabama +69 locations
Conditions: Type 2 Diabetes, Hypogonadism
Study of the Efficacy of ESTRATEST® H.S. Tablets in Relieving Menopausal Symptoms in Estrogenized Postmenopausal Women
Completed
To determine whether treatment with ESTRATEST® H.S. Tablets is superior to treatment with esterified estrogens tablets
Gender:
FEMALE
Ages:
Between 30 years and 65 years
Trial Updated:
01/15/2015
Locations: Site 66, Huntsville, Alabama +76 locations
Conditions: Menopause
Observation Study of T-Gel (1%) in Treatment of Adolescent Boys With Hypogonadism
Completed
This study is to observe efficacy and safety after T-Gel 1% treatment in delayed puberty adolescents. Subjects who complete this trial may enter a 3 month extension study (UMD-01-090E).
Gender:
MALE
Ages:
Between 13 years and 17 years
Trial Updated:
01/15/2015
Locations: Site 130, Birmingham, Alabama +18 locations
Conditions: Primary or Secondary Hypogonadism, Constitutional Delay in Growth and Puberty (CDGP)
A Study of Ejaculatory Dysfunction in Men With Low Testosterone Levels
Completed
The purpose of this study is to see if testosterone solution 2% can impact symptoms of ejaculatory dysfunction in men with low testosterone.
Gender:
MALE
Ages:
26 years and above
Trial Updated:
12/12/2014
Locations: For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Los Angeles, California +6 locations
Conditions: Ejaculatory Dysfunction, Hypogonadism
NES Gel-1, To Evaluate Nestorone Gel in Combination With Testosterone Gel
Completed
The purpose of this study is to determine the usefulness of two transdermal gels to be used in the future development for a male contraceptive.
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
12/03/2014
Locations: Harbor-UCLA Medical Center, Torrance, California +1 locations
Conditions: Contraception
One Week Comparison Study of PTH and PTHrP Infusions
Withdrawn
This is a dose escalation study to determine the maximum tolerable dose of Parathyroid Hormone-related Protein, PTHrP, or Parathyroid Hormone, PTH, that can be given safely over one week in healthy African-American volunteers. The investigators plan to infuse low doses of intravenous PTHrP or PTH to determine if it leads to a sustained and progressive suppression of bone formation as occurs in humoral hypercalcemia of malignancy (HHM) or an increase in bone formation as occurs in hyperparathyroi... Read More
Gender:
ALL
Ages:
Between 24 years and 35 years
Trial Updated:
12/03/2014
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Osteoporosis, Hypercalcemia of Malignancy, Hyperparathyroidism, Bone Diseases, Endocrine
The Effect of Testosterone Topical Solution (LY900011) in Hypogonadal Men With Suboptimal Response to a Topical Testosterone Gel
Completed
This study will evaluate if testosterone solution can raise testosterone hormone levels into the normal range after treatment for up to 9 Weeks, in those participants with a documented history of subtherapeutic levels \[total testosterone \<300 nanograms per deciliter (ng/dL)\] when previously treated with a topical testosterone gel.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/21/2014
Locations: For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Encinitas, California +20 locations
Conditions: Hypogonadism
A Study of Effect of Deodorant and Axillary Hair on Testosterone Absorption in Healthy Participants
Completed
This study will evaluate the effect of deodorant and antiperspirant use and the presence of underarm hair on the absorption of testosterone. Each participant in this study will receive 6 single doses of 30 milligrams (mg) testosterone applied as a solution to each underarm. There is a minimum one day washout period between each dose. This study will last approximately 24 days not including screening. Screening is required within 30 days prior to the start of the study.
Gender:
MALE
Ages:
50 years and above
Trial Updated:
10/07/2014
Locations: For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Daytona Beach, Florida +1 locations
Conditions: Healthy Participants
A Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment With 12.5 mg or 25 mg Androxal or AndroGel 1.62%
Completed
This is a Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men with Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment with the 12.5 mg or 25 mg Androxal or AndroGel 1.62%.
Gender:
MALE
Ages:
Between 18 years and 60 years
Trial Updated:
09/29/2014
Locations: Not set, Jacksonville, Florida +7 locations
Conditions: Secondary Hypogonadism