There are currently 9 active clinical trials seeking participants for Heart Diseases research studies. The states with the highest number of trials for Heart Diseases participants are .
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR
NCT03142152
Recruiting
The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart failure with functional regurgitation (FMR).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/22/2025
Locations: Dignity Health Research Institute at Mercy Gilbert and Chandler Regional Medical Centers, Gilbert, Arizona +70 locations
Conditions: Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases
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Abbott Structural Heart Device Registry
NCT06590467
Recruiting
The Abbott Structural Heart (SH) Registry is being conducted to confirm the safety and performance of Abbott's SH devices in a post-market, real-world setting. The Registry primarily involves gathering data from routine hospital practices and standard-of-care (SOC) procedures administered to patients. All devices used in these procedures must be commercially available to the participating site. A list of specific devices covered by the Registry are available upon request from the Sponsor. Data g... Read More
Gender:
ALL
Ages:
All
Trial Updated:
07/29/2025
Locations: CHRU Hopital de Pontchaillou, Rennes, Brittan +17 locations
Conditions: Heart Diseases, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect, PFO - Patent Foramen Ovale, PIVSD - Post Infarct Muscular Ventricular Septal Defect, Valvular Heart Disease
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Personalized Responses to Dietary Composition Trial 3
NCT04735835
Recruiting
The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and individualized dietary advice. The study incorporates both standardized and controlled dietary intervention, for the purpose of testing postprandial responses to specific mixed meals, in addition to a free-living period with a dietary record for measuring responses to a large v... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/11/2025
Locations: Zoe US Inc., Needham, Massachusetts +1 locations
Conditions: Diabetes, Heart Diseases, Diet Habit, Diet Modification, Healthy, Obesity, Metabolism, Microbial Colonization
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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
NCT04124120
Recruiting
The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will improve clinical outcomes and quality of life (QOL) compared to single arterial grfating (SAG). The specific aims of ROMA:Women are: Aim 1: Determine the impact of MAG vs SAG on major adverse cardiac and cerebrovascular events in women undergoing coronary artery bypass grfating (CABG). The investigators will compare major adverse cardiac and cerebrovascular events (death, stroke, non-procedural myocar... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/04/2025
Locations: Cedars-Sinai Medical Center, Los Angeles, California +140 locations
Conditions: Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
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Mayo AVC Registry and Biobank
NCT03049254
Recruiting
Arrhythmogenic ventricular cardiomyopathy (AVC) is a genetic condition which affects the heart and can lead to heart failure and rhythm problems, of which, sudden cardiac arrest or death is the most tragic and dangerous. Diagnosis and screening of blood-relatives is very difficult as the disease process can be subtle, but sufficient enough, so that the first event is sudden death. The Mayo Clinic AVC Registry is a collaboration between Mayo Clinic, Rochester, USA and Papworth Hospital, Cambridg... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/31/2025
Locations: Mayo Clinic, Rochester, Minnesota +1 locations
Conditions: Arrhythmogenic Right Ventricular Cardiomyopathy, Cardiomyopathies, Heart Diseases, Cardiovascular Diseases, Sudden Cardiac Arrest, Sudden Cardiac Death, Arrhythmogenic Right Ventricular Dysplasia, Arrhythmogenic Ventricular Cardiomyopathy, Familial Dilated Cardiomyopathy, Cardiovascular Abnormalities, Sarcoidosis, Cardiac Arrhythmia, Cardiac Sarcoidosis, Myocarditis, Inflammatory Cardiomyopathy, Ventricular Tachycardia, Right Ventricular Outflow Tract Ventricular Tachycardia
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Therapy to Maintain Remission in Dilated Cardiomyopathy
NCT06091475
Recruiting
One third of patients diagnosed with heart failure demonstrate left ventricular reverse remodelling and recovery of cardiac function following a period of medical therapy. The TRED-HF trial investigated the impact of therapy withdrawal in this cohort and found that 40% of patients relapsed within 6 months of stopping treatment. In this follow-on study, the investigators will investigate the safety of therapy withdrawal of sodium cotransporter 2 inhibitors (SGLT2i) and mineralocorticord receptor... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
09/03/2024
Locations: Royal Brompton Hospital, London, Not set
Conditions: Heart Failure, Cardiomyopathy, Dilated, Cardiomyopathies, Heart Diseases
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Cardiometabolic Health in First Time Pregnancy
NCT05856318
Recruiting
Women who experience placental complications (syndromes) during pregnancy, such as pre-eclampsia (high blood pressure and kidney problems), gestational hypertension (high blood pressure during pregnancy) and fetal growth restriction (baby being small) have twice the risk of developing heart disease and diabetes later in life, compared to women who have a healthy pregnancy. This study aims to assess risk factors for heart disease and diabetes in women who are actively trying to conceive, before... Read More
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
04/05/2024
Locations: Cambridge University Hospitals NHS Foundation Trust, Cambridge, Not set +6 locations
Conditions: Cardiometabolic Health, Pregnancy Related, Diabetes, Placental; Syndrome, Dysfunction, Heart Diseases
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The Living With a Long-Term Condition Study
NCT06072287
Recruiting
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs). Being able to measure whether psychological distress is related to living with a LTC would allow researchers and clinicians to provide interventions specifically tailored to the challenges of living with a LTC and therefore provide the most appropriate support for these patients. Such a measure would also be useful in research to identify the presence... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2023
Locations: King's College London, London, Not set
Conditions: Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders, Stroke, CKD, Copd, Fibromyalgia, Pain, Heart Diseases, Heart Disease Chronic, Dementia, Diabetes, Epilepsy, Heart Failure, High Blood Pressure, Hypertension, Hiv, AIDS, IBD, IBS, Liver Diseases, Long COVID, Lupus Erythematosus, Multiple Sclerosis, Obesity, Osteoarthritis, Arthritis, Rheumatoid Arthritis, Osteoporosis, Parkinson Disease, Sickle Cell Disease, Hepatitis, Endometriosis, PCOS, Neurological Disorder, POTS - Postural Orthostatic Tachycardia Syndrome, MND (Motor Neurone DIsease), Cystic Fibrosis, Migraine, Spondylitis, Celiac Disease, Hidradenitis Suppurativa, Eczema, ME/CFS
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NT-proBNP Selected Prevention of Cardiac Events in Diabetic Patients
NCT02817360
Recruiting
Purpose and rationale The purpose of this study is to evaluate the effect of high dose Renin-Angiotensin System (RAS)-antagonists and beta-blocker treatment for the primary prevention of cardiac events in a population of patients with Type 2 diabetes mellitus (T2DM) with no evidence of a preexisting cardiac disease. An additional aim is to demonstrate an interaction between concentrations of amino-terminal pro-B type natriuretic peptide (NT-proBNP as a surrogate of imminent cardiac risk) and tre... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/12/2023
Locations: Internistische Ordination, Mödling, Niederösterreich +20 locations
Conditions: Heart Diseases, Diabetes Mellitus, Type 2
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