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Paclitaxel Treatment Options in United Kingdom
A collection of 293 research studies where Paclitaxel is the interventional treatment. These studies are located in the United Kingdom . Paclitaxel is used for conditions such as Breast Cancer, Ovarian Cancer and Non-Small Cell Lung Cancer.
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A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection, 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer, Compared to Nab-paclitaxel+Gemcitabine Treatment
Completed
The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for cancer therapy, namely 5 fluorouracil/leucovorin (5FU/LV) plus oxaliplatin compared to nab-paclitaxel + gemcitabine treatment in improving the overall survival of patients not previously treated for metastatic pancreatic cancer.
The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for cancer therapy, namely 5 fluorouracil/leucovorin (5FU/LV) plus oxaliplatin compared to nab-paclitaxel + gemcitabine treatment in improving the overall survival of patients not previously treated for metastatic pancreatic cancer. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +199 locations
University of Alabama at Birmingham, Birmingham, Alabama
Banner Health- MD Anderson Cancer Center, Gilbert, Arizona
Mayo Clinic - Scottsdale, Phoenix, Arizona
Comprehensive Blood And Cancer Center, Bakersfield, California
University of California- Irvine Health Cancer Cente, Costa Mesa, California
City of Hope National Medical Center, Duarte, California
University of California, Los Angeles (UCLA), Los Angeles, California
St. Jude Hospital Yorba Linda dba St. Joseph Heritage Healthcare, Orange, California
University of California - Irvine Medical Center, Orange, California
Torrance Memorial Physician Network Cancer Care, Redondo Beach, California
Sutter Health Sacramento, Sacramento, California
Presbyterian Intercommunity Hospital (PIH), Whittier, California
UC Health Memorial Hospital, Colorado Springs, Colorado
Rocky Mountain Cancer Center, Denver, Colorado
Mount Sinai Medical Center of Florida, Inc., Miami Beach, Florida
Miami Cancer Institute, Miami, Florida
Florida Cancer Specialists - Fort Myers, Sarasota, Florida
Florida Cancer Specialists - Panhandle, Tallahassee, Florida
Florida Cancer Specialists - St. Petersburg, Tampa, Florida
Florida Cancer Specialists - East, West Palm Beach, Florida
Rush University Medical Center, Chicago, Illinois
Edward Hospital - Elmhurst, Elmhurst, Illinois
Illinois CancerCare - Peoria, Peoria, Illinois
Carle Cancer Center, Urbana, Illinois
Fort Wayne Medical Oncology and Hematology, Fort Wayne, Indiana
Siouxland Hematology - Oncology Associates, LLP, Sioux City, Iowa
University of Kentucky Markey Cancer Center, Lexington, Kentucky
Pikeville Medical Center, Pikeville, Kentucky
Hematology Oncology Clinic, Baton Rouge, Louisiana
Ochsner Clinic Foundation, New Orleans, Louisiana
Willis-Knighton Cancer Center, Shreveport, Louisiana
Maine Center for Cancer Medicine, Scarborough, Maine
Maryland Oncology Hematology, Silver Spring, Maryland
Beth Israel Deaconess, Boston, Massachusetts
Henry Ford Health System, Detroit, Michigan
Cancer and Hematology Centers of Western Michigan, Grand Rapids, Michigan
Health Partners Institute, Minneapolis, Minnesota
Mayo Clinic - Rochester, Rochester, Minnesota
Research Medical Center, Kansas City, Missouri
Frontier Cancer Center, Billings, Montana
Oncology Hematology West P.C. dba Nebraska Cancer Specialists, Omaha, Nebraska
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada
Clinical Research Alliance, Inc, Lake Success, New York
David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York, New York
University of Rochester, Rochester, New York
Stony Brook University Medical Center, Stony Brook, New York
Messino Cancer Center, Asheville, North Carolina
The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solovev Research Institute (OSUCCC - James), Columbus, Ohio
Toledo Clinic Cancer Center, Toledo, Ohio
University of Oklahoma - Health Sciences Center, Oklahoma City, Oklahoma
Oncology Associates of Oregon, Eugene, Oregon
Compass Oncology - Rose Quarter Cancer Center, Portland, Oregon
Kaiser Permanente - Northwest, Portland, Oregon
Oregon Health & Science University (OHSU), Portland, Oregon
University of Pittsburgh Medical Center (UPMC) - Hillman Cancer Center, Pittsburgh, Pennsylvania
Greenville Hospital System, Greenville, South Carolina
Chattanooga Oncology Hematology Care - Tennessee Oncology, Chattanooga, Tennessee
The West Cancer Center, Memphis, Tennessee
Sarah Cannon and HCA Research Institute, Nashville, Tennessee
Texas Oncology - Austin, Austin, Texas
Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas, Texas
The Center for Cancer and Blood Disorders, Fort Worth, Texas
Baylor College of Medicine, Houston, Texas
Houston Methodist Research Institute, Houston, Texas
MD Anderson Cancer Center, Houston, Texas
Oncology Consultants, Houston, Texas
Texas Oncology - Tyler, Tyler, Texas
Texas Oncology - Wichita Falls, Wichita Falls, Texas
Utah Cancer Specialists, Salt Lake City, Utah
Virginia Cancer Specialists, Fairfax, Virginia
Blue Ridge Cancer Care, Wytheville, Virginia
Froedtert Hospital and the Medical College of Wisconsin, Milwaukee, Wisconsin
Bankstown-Lidcombe Hospital, Bankstown, Not set
Monash Medical Centre, Clayton, Not set
Fiona Stanley Hospital, Murdoch, Not set
Sir Charles Gairdner Hospital, Nedlands, Not set
St John of God Subiaco Hospital, Subiaco, Not set
Queen Elizabeth Hospital, Woodville South, Not set
Medizinische Universitaet Graz, Graz, Not set
Ordensklinikum Linz GmbH Barmherzige Schwestern, Linz, Not set
SCRI-CCCIT Gemeinnutzige Gmbh- Gemeinnutzige Salzburger Landeskliniken Betriebsgesmbh, Salzburg, Not set
Medical University of Vienna, Vienna, Not set
Onze-Lieve-Vrouwziekenhuis, Aalst, Not set
ASBL Grand Hôpital de Charleroi (GHdC), Site Notre Dame, Charleroi, Not set
Universitair Ziekenhuis Antwerpen (UZA), Edegem, Not set
University Hospital Gent, Gent, Not set
Hospital centre Jolimont, Haine-Saint-Paul, Not set
University Hospital (UZ) Leuven, Leuven, Not set
University Hospital Mont-Godinne, Yvoir, Not set
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos, Not set
Centro Regional Integrado de Oncologia (CRIO), Ceara, Not set
Instituto de Oncologia do Parana - IOP, Curitiba, Not set
Centro de Pesquisas Oncológicas - CEPON, Florianópolis, Not set
Hospital de Caridade de Ijui, Ijuí, Not set
Clinica Neoplasias Litoral, Itajaí, Not set
Hospital Bruno Born, Lajeado, Not set
Centro de Pesquisas Clinicas de Natal - CPCLIN, Natal, Not set
Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Not set
Instituto Nacional Do Cancer (INCA), Rio de Janeiro, Not set
Instituto COI, Rio De Janeiro, Not set
Instituto Brasileiro de Controle do Cancer - IBCC (Sao Paulo), San Paolo, Not set
CIP Centro Integrado de Pesquisas do Hospital de Base, São José Do Rio Preto, Not set
Hospital Alemão Oswaldo Cruz, São Paulo, Not set
Instituto do Cancer do Estado de São Paulo (ICESP), São Paulo, Not set
Alberta Health Services Cross Cancer Institute, Edmonton, Not set
Queen Elizabeth II Health Sciences Centre, Halifax, Not set
McGill University Faculty of Medicine - Royal Victoria Hospital, Montréal, Not set
Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Not set
Masarykuv onkologicky ustav, Brno, Not set
Fakultni nemocnice Hradec Kralove, Hradec Králové, Not set
University Hospital Olomouc, Department of Oncology, Olomouc, Not set
Thomayerova Nemocnice, Praha, Not set
CHRU de Tours - Hôpital Trousseau, Chambray-lès-Tours, Not set
Centre Oscar Lambret, Lille, Not set
Hôpital Edouard Herriot, Lyon, Not set
Centre Leon Berard, Lyon, Not set
Hopital Prive Jean Mermoz, Lyon, Not set
Centre Antoine-Lacassagne, Nice, Not set
Hopital Saint Louis, Paris, Not set
CHU Bordeaux - Hopital Haut-Leveque, Pessac, Not set
Centre Hospitalier Universitaire de Poitiers - Poitiers University Hospital, Poitiers Cedex, Not set
Strasbourg Oncologie Liberale, Strasbourg, Not set
Charité - Universitaetsmedizin Berlin, Berlin, Not set
St. Josef-Hospital, Bochum, Not set
Klinikum Esslingen GmbH, Esslingen, Not set
Krankenhaus Nordwest, Frankfurt, Not set
Studiengesellschaft BSF, Halle, Not set
Martin Luther Universitat Halle-Wittenberg, Halle, Not set
Facharztzentrum Eppendorf, Hamburg, Not set
Marienkrankenhaus Hamburg, Hamburg, Not set
Asklepios Klinik Altona, Hamburg, Not set
Medizinische Hochschule Hannover, Hannover, Not set
Slk-Kliniken, Heilbronn, Not set
Klinikum Mannheim, Mannheim, Not set
Krankenhaus St. Franziskus - Kliniken Maria Hilf GmbH, Mönchengladbach, Not set
Universitaetsklinikum Tuebingen, Tuebingen, Not set
Universitaetsklinikum Ulm, Ulm, Not set
Agios Savvas Anticancer Hospital, Athens, Not set
General Hospital of Athens - Laiko, Athens, Not set
National and Kapodistrian University of Athens, Athens, Not set
University General Hospital of Ioannina, Ioánnina, Not set
Theagenion Hospital, Thessaloníki, Not set
Dél-pesti Centrumkórház - Szent László Kórház telephely, Budapest, Not set
Országos Onkológiai Intézet, Budapest, Not set
Semmelweis Egyetem Belgyógyászati és Hematológiai Klinika, Budapest, Not set
Debreceni Egyetem Klinikai Kozpont, Debrecen, Not set
Somogy Megyei Kaposi Mor Oktato Korhaz, Kaposvár, Not set
Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház-Rendelointézet, Szolnok, Not set
Soroka Medical Center, Beer Sheva, Not set
Rambam Health Care Campus, Haifa, Not set
Policlinico S. Orsola-Malpighi, Bologna, Not set
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori, Meldola, Not set
Istituto Europeo di Oncologia, Milano, Not set
Azienda Ospedaliero-Universitaria di Modena, Modena, Not set
AUSL di Piacenza-Ospedale Guglielmo Da Saliceto, Piacenza, Not set
Azienda Ospedaliero Universitaria Pisana, Pisa, Not set
AOU Ospedali Riuniti di Ancona, Torrette, Not set
Azienda Ospedaliera - Universitaria Integrata di Verona - Ospedale Borgo Roma, Verona, Not set
Inje University Haeundae Paik Hospital, Busan, Not set
National Cancer Center, Goyang-si, Not set
CHA Bundang Medical Center, Gyeonggi-do, Not set
Asan Medical Center, Seoul, Not set
Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
Hospital de Braga, Braga, Not set
Centro Hospitalar Universitario de Lisboa Norte - Hospital de Santa Maria, Lisboa, Not set
Champalimaud Cancer Center, Lisbon, Not set
Unidade Local de Saude Matosinhos E.P.E. Hospital Pedro Hispano, Senhora da Hora, Not set
Centro Hospitalar de Vila Nova de Gaia/Espinho EPE, Vila Nova de Gaia, Not set
Evimed LLC, Chelyabinsk, Not set
Limited Liability Company- Clinica Druzhkovyh, Kazan, Not set
Kursk Regional Clinical Oncology Dispensary, Kursk, Not set
Main Military Clinical Hospital named after N.N. Burdenko, Moscow, Not set
Volga District Medical Centre, Novgorod, Not set
Federal State Budgetary Institution - Russian Scientific Center of Radiology and Surgical Technologies n.a. academician A.M.Granov, Saint-Petersburg, Not set
Hospital General Universitario de Elche, Alicante, Not set
Hospital Universitario de Badajoz, Badajoz, Not set
Hospital Germans Trias i Pujol, Badalona, Not set
Hospital Quironsalud Barcelona, Barcelona, Not set
Hospital de la Santa Creu i Sant Pau Barcelona, Barcelona, Not set
Hospital Vall D Hebron, Barcelona, Not set
Hospital Clinic Barcelona, Barcelona, Not set
Corporacio Sanitaria Parc Tauli - Hospital de Sabadell, Barcelona, Not set
Institut Catala d'Oncologia - L'Hospitalet, Barcelona, Not set
Complejo Hospitalario Universitario de Granada - Hospital Universitario Virgen de las Nieves, Granada, Not set
Hospital General Universitario Gregorio Marañon, Madrid, Not set
Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Centro Integral Oncologico Clara Campal, Madrid, Not set
Hospital Regional Universitario de Malaga, Málaga, Not set
Complejo Hospitalario de Navarra, Pamplona, Not set
Hospital Universitario Marques de Valdecilla, Santander, Not set
Hospital Universitario Miguel Servet, Zaragoza, Not set
Guy's and St. Thomas' NHS Foundation Trust, London, Not set
Royal Marsden Foundation Trust, London, Not set
Royal Marsden Foundation Trust, London, Not set
Imperial College Healthcare NHS Trust, London, Not set
Cancer Research UK - Christie Hospital Foundation NHS Trust - Dept of Medical Oncology, Manchester, Not set
Nottingham City Hospital, Nottingham, Not set
Conditions: Metastatic Adenocarcinoma of the Pancreas
Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Versus Chemotherapy for Endometrial Carcinoma (ENGOT-en9 / MK-7902-001)
Completed
The purpose of this study is to compare the efficacy of pembrolizumab + lenvatinib to chemotherapy in female participants with Stage III, IV, or recurrent endometrial carcinoma. It is hypothesized that the combination of pembrolizumab + lenvatinib will be superior to chemotherapy for progression-free survival (PFS) per Response Evaluation Criteria In Solid Tumors version 1.1 (RECIST 1.1) by blinded independent central review (BICR). It is also hypothesized that the combination of pembrolizumab +... Read More
The purpose of this study is to compare the efficacy of pembrolizumab + lenvatinib to chemotherapy in female participants with Stage III, IV, or recurrent endometrial carcinoma. It is hypothesized that the combination of pembrolizumab + lenvatinib will be superior to chemotherapy for progression-free survival (PFS) per Response Evaluation Criteria In Solid Tumors version 1.1 (RECIST 1.1) by blinded independent central review (BICR). It is also hypothesized that the combination of pembrolizumab + lenvatinib will be superior to chemotherapy for overall survival (OS).
As of Amendment 7 eligible participants on study completion will be able to transition to an extension study, if available, in which they can continue to receive pembrolizumab monotherapy, lenvatinib monotherapy, or a combination of both pembrolizumab and lenvatinib as received in the parent study. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: University of South Alabama, Mitchell Cancer Institute ( Site 0245), Mobile, Alabama +194 locations
University of South Alabama, Mitchell Cancer Institute ( Site 0245), Mobile, Alabama
Arizona Oncology Associates PC- HOPE ( Site 8005), Tucson, Arizona
UCLA Hematology and Oncology Clinic (Westwood) ( Site 0233), Los Angeles, California
University of Colorado Cancer Center ( Site 0204), Aurora, Colorado
Smilow Cancer Hospital at Yale New Haven ( Site 0202), New Haven, Connecticut
University of Miami Health System ( Site 0249), Miami, Florida
Georgia Cancer Center at Augusta University ( Site 0222), Augusta, Georgia
Women's Cancer Care ( Site 0208), Covington, Louisiana
Maine Medical Partners ( Site 0217), Scarborough, Maine
Minnesota Oncology Hematology, PA ( Site 8003), Minneapolis, Minnesota
Memorial Sloan-Kettering Cancer Center At Basking Ridge ( Site 0268), Basking Ridge, New Jersey
John Theurer Cancer Center at Hackensack University Med Ctr ( Site 0226), Hackensack, New Jersey
Memorial Sloan Kettering Cancer Center- Monmouth ( Site 0273), Middletown, New Jersey
MSKCC-Bergen ( Site 0276), Montvale, New Jersey
Holy Name Medical Center ( Site 0235), Teaneck, New Jersey
Memorial Sloan-Kettering Cancer Center at Commack ( Site 0267), Commack, New York
Memorial Sloan Kettering Cancer Center - West Harrison ( Site 0274), Harrison, New York
The Blavatnik Family- Chelsea Medical Center at Mount Sinai ( Site 0206), New York, New York
Memorial Sloan Kettering Cancer Center ( Site 0246), New York, New York
University of Rochester ( Site 0238), Rochester, New York
Memorial Sloan Kettering Cancer Center - Nassau ( Site 0275), Uniondale, New York
University of North Carolina- Chapel Hill ( Site 0254), Chapel Hill, North Carolina
Roger Maris Cancer Center ( Site 0277), Fargo, North Dakota
Willamette Valley Cancer Institute and Research Center ( Site 8004), Eugene, Oregon
Sanford Cancer Center Oncology Clinic ( Site 0205), Sioux Falls, South Dakota
Parkland Health & Hospital System ( Site 0272), Dallas, Texas
University of Texas Southwestern Medical Center ( Site 0264), Dallas, Texas
Texas Oncology-The Woodlands ( Site 8000), The Woodlands, Texas
Legacy Salmon Creek Medical Center ( Site 0253), Vancouver, Washington
IDIM Instituto de Diagnostico e Investigaciones Metabolicas ( Site 2607), Caba, Buenos Aires
Hospital Italiano de La Plata ( Site 2601), La Plata, Buenos Aires
Instituto de Investigaciones Clinicas Mar del Plata ( Site 2606), Mar del Plata, Buenos Aires
Hospital Aleman ( Site 2600), Buenos Aires, Not set
Hospital Italiano de Buenos Aires ( Site 2603), Buenos Aires, Not set
Centro Oncologico Riojano Integral ( Site 2605), La Rioja, Not set
Chris OBrien Lifehouse ( Site 1605), Camperdown, New South Wales
Prince of Wales Hospital [Australia] ( Site 1603), Randwick, New South Wales
Royal North Shore Hospital ( Site 1600), St Leonards, New South Wales
The Crown Princess Mary Cancer Centre - Westmead Hospital ( Site 1602), Westmead, New South Wales
Mater Misericordiae Ltd ( Site 1608), South Brisbane, Queensland
Monash Health ( Site 1606), Clayton, Victoria
Epworth Freemasons Hospital ( Site 1609), Melbourne, Victoria
Sir Charles Gairdner Hospital ( Site 1604), Nedlands, Western Australia
Universitatsklinik fuer Frauenheilkunde und Geburtshilfe ( Site 3301), Graz, Steiermark
Medizinische Universitat Innsbruck ( Site 3302), Innsbruck, Tirol
Medizinische Universitat Wien ( Site 3300), Vienna, Wien
UZA University Hospital Antwerp ( Site 3204), Edegem, Antwerpen
UZ Leuven ( Site 3200), Leuven, Antwerpen
Cliniques Universitaires Saint-Luc ( Site 3203), Brussels, Bruxelles-Capitale, Region De
AZ Maria Middelares Gent ( Site 3202), Gent, Oost-Vlaanderen
AZ Delta ( Site 3206), Roeselare, West-Vlaanderen
Instituto do Cancer do Ceara ( Site 2703), Fortaleza, Ceara
Hospital Araujo Jorge Associacao de Combate ao Cancer de Goias ( Site 2702), Goiania, Goias
Faculdade de Medicina da Universidade Federal de Minas Gerais ( Site 2708), Belo Horizonte, Minas Gerais
Hospital de Caridade de Ijui ( Site 2712), Ijui, Rio Grande Do Sul
Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da Pucrs ( Site 2701), Porto Alegre, Rio Grande Do Sul
Hospital de Base de Sao Jose de Rio Preto ( Site 2704), Sao Jose do Rio Preto, Sao Paulo
Instituto Nacional do Cancer II ( Site 2707), Rio de Janeiro, Not set
Clinica de Pesquisas e Ctro de Estudos Onc. Ginecol. e Mamaria Ltda ( Site 2706), Sao Paulo, Not set
Real e Benemerita Associacao Portuguesa de Beneficencia ( Site 2713), Sao Paulo, Not set
A.C. Camargo Cancer Center ( Site 2705), Sao Paulo, Not set
Cross Cancer Institute ( Site 0408), Edmonton, Alberta
BC Cancer-Kelowna - Sindi Ahluwalia Hawkins Centre ( Site 0402), Kelowna, British Columbia
BC Cancer-Vancouver Center ( Site 0412), Vancouver, British Columbia
Juravinski Cancer Centre ( Site 0406), Hamilton, Ontario
Kingston Health Sciences Centre ( Site 0401), Kingston, Ontario
The Credit Valley Hospital ( Site 0403), Mississauga, Ontario
Sunnybrook Research Institute ( Site 0410), Toronto, Ontario
Princess Margaret Cancer Centre ( Site 0409), Toronto, Ontario
CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont ( Site 0414), Montreal, Quebec
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0411), Montreal, Quebec
McGill University Health Centre ( Site 0404), Montreal, Quebec
CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 0417), Sherbrooke, Quebec
Anhui Provincial Cancer Hospital ( Site 2509), Hefei, Anhui
Beijing Obstetrics and Gynecology Hospital Capital Medical University ( Site 2505), Beijing, Beijing
Peking Union Medical College Hospital ( Site 2501), Beijing, Beijing
Beijing Cancer Hospital ( Site 2504), Beijing, Beijing
Chongqing Cancer Hospital ( Site 2513), Chongqing, Chongqing
The First Affiliated Hospital.Sun Yat-sen University ( Site 2507), Guangzhou, Guangdong
Guang Xi Tumour Hospital, Department of Chemotherapy ( Site 2517), Nanning, Guangxi
Hubei Cancer Hospital ( Site 2510), Wuhan, Hubei
Xiangya Hospital Central-South University ( Site 2512), Changsha, Hunan
Nanjing Maternity and Child Health Care Hospital ( Site 2508), Nanjing, Jiangsu
The first affiliated Hospital of Xi an Jiaotong University ( Site 2502), XI An, Shaanxi
Fudan University Shanghai Cancer Center ( Site 2500), Shanghai, Shanghai
Obstetrics and Gynecology Hosp. Fudan University ( Site 2503), Shanghai, Shanghai
The First Affiliated Hospital of Xinjiang Medical University ( Site 2515), Urumqi, Xinjiang
Women s Hospital School of Medicine Zhejiang University ( Site 2511), Hangzhou, Zhejiang
Zhejiang Cancer Hospital ( Site 2506), Hangzhou, Zhejiang
Universitaetsmedizin Mannheim. Klinik fuer Kinder und Jugendmedizin ( Site 0622), Mannheim, Baden-Wurttemberg
Universitaetsklinikum Muenster ( Site 0615), Muenster, Baden-Wurttemberg
Caritas-Krankenhaus St. Josef Regensburg ( Site 0613), Regensburg, Bayern
HELIOS Dr. Horst Schmidt Kliniken Wiesbaden ( Site 0623), Wiesbaden, Hessen
Universitaetsklinikum Essen ( Site 0616), Essen, Nordrhein-Westfalen
Universitaetsklinikum Jena ( Site 0612), Jena, Thuringen
Charite Universitaetsmedizin Berlin ( Site 0609), Berlin, Not set
Cork University Hospital ( Site 1400), Cork, Not set
St James Hospital ( Site 1401), Dublin, Not set
Meir Medical Center ( Site 0702), Kfar-Saba, Central
Edith Wolfson Medical Center ( Site 0703), Holon, Tell Abib
Rambam Medical Center ( Site 0700), Haifa, Not set
Chaim Sheba Medical Center ( Site 0707), Ramat Gan, Not set
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori ( Site 0800), Meldola, Emilia-Romagna
Policlinico Universitario Agostino Gemelli ( Site 0805), Rome, Roma
Ospedale dell Angelo ( Site 0810), Mestre, Venezia
Medical Oncology Ospedale San Donato ( Site 0812), Arezzo, Not set
IRCCS Giovanni Paolo II. Ospedale Oncologico ( Site 0801), Bari, Not set
Ospedale Policlinico S. Orsola-Malpighi ( Site 0803), Bologna, Not set
Ospedale Antonio Perrino ( Site 0806), Brindisi, Not set
Azienda Ospedaliera per l Emergenza Cannizzaro ( Site 0807), Catania, Not set
Istituto Nazionale Tumori Fondazione Pascale ( Site 0808), Napoli, Not set
Ehime University Hospital ( Site 2413), Toon, Ehime
Kurume University Hospital ( Site 2403), Kurume, Fukuoka
Gunma Prefectural Cancer Center ( Site 2404), Ota, Gunma
National Hospital Organization Hokkaido Cancer Center ( Site 2408), Sapporo, Hokkaido
Hyogo Cancer Center ( Site 2414), Akashi, Hyogo
Nippon Medical School Musashi Kosugi Hospital ( Site 2417), Kawasaki, Kanagawa
St. Marianna University School of Medicine Hospital ( Site 2416), Kawasaki, Kanagawa
University of the Ryukyus Hospital ( Site 2412), Nakagami-gun, Okinawa
Saitama Medical University International Medical Center ( Site 2410), Hidaka, Saitama
Saitama Cancer Center ( Site 2406), Kitaadachi-gun, Saitama
National Defense Medical College Hospital ( Site 2418), Tokorozawa, Saitama
Kyorin University Hospital ( Site 2402), Mitaka, Tokyo
National Hospital Organization Kyushu Cancer Center ( Site 2405), Fukuoka, Not set
Niigata Cancer Center Hospital ( Site 2415), Niigata, Not set
Osaka International Cancer Institute ( Site 2409), Osaka, Not set
The Cancer Institute Hospital of JFCR ( Site 2401), Tokyo, Not set
Showa University Hospital ( Site 2419), Tokyo, Not set
Keio University Hospital ( Site 2411), Tokyo, Not set
Seoul National University Bundang Hospital ( Site 1802), Seongnam-si, Kyonggi-do
Seoul National University Hospital ( Site 1801), Seoul, Not set
Severance Hospital Yonsei University Health System ( Site 1804), Seoul, Not set
Asan Medical Center ( Site 1800), Seoul, Not set
Samsung Medical Center ( Site 1803), Seoul, Not set
Hospital San Lucas Cardiologica del Sureste ( Site 3103), Tuxtla Gutierrez, Chiapas
I CAN Oncology SA de SV ( Site 3102), Monterrey, Nuevo Leon
Centro Estatal de Cancerologia de Chihuahua ( Site 3101), Chihuahua, Not set
Consultorio Dentro de la Torre Medica Dalinde Oncologia Medica ( Site 3108), Ciudad de Mexico, Not set
Centro de Investigacion Clinica Gramel ( Site 3107), Mexico City, Not set
Centro Oncologico Internacional. SEDNA ( Site 3106), Mexico City, Not set
Samodzielny Publiczny Szpital Kliniczny Nr 1 w Lublinie ( Site 1008), Lublin, Dolnoslaskie
Instytut Centrum Zdrowia Matki Polki ( Site 1020), Lodz, Lodzkie
Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie ( Site 1019), Krakow, Malopolskie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 1009), Warsaw, Mazowieckie
Szpital Kliniczny im Ks Anny Mazowieckiej ( Site 1011), Warszawa, Mazowieckie
Bialostockie Centrum Onkologii ( Site 1005), Bialystok, Podlaskie
Centrum Onkologii Instytut im. MSC Oddział w Gliwicach ( Site 1017), Gliwice, Slaskie
Wielkopolskie Centrum Onkologii im.M.Sklodowskiej-Curie ( Site 1004), Poznan, Wielkopolskie
Krasnoyarsk Regional Clinical oncology dispensary ( Site 1118), Krasnoyarsk, Krasnoyarskiy Kray
Russian Oncological Research Center n.a. N.N.Blokhin of MoH ( Site 1100), Moscow, Moskva
FSBI-FRCC of Special Types Med. Care and Technologies FMBA of Russia ( Site 1102), Moscow, Moskva
Medical Rehabilitation Center ( Site 1101), Moscow, Moskva
Samara Regional Clinical Oncology Center ( Site 1117), Samara, Samarskaya Oblast
St.Petersburg Clinical Hospital RAS ( Site 1124), Saint Petersburg, Sankt-Peterburg
SPb SBHI City Clinical Oncological Dispensary ( Site 1104), Saint Petersburg, Sankt-Peterburg
Railway Hospital of OJSC ( Site 1122), Saint-Petersburg, Sankt-Peterburg
National Medical Research Center of Oncology N.A. N.N. Petrov ( Site 1103), Saint-Petersburg, Sankt-Peterburg
Republican Clinical Oncology Dispensary of Tatarstan MoH ( Site 1108), Kazan, Tatarstan, Respublika
Siberian State Medical University ( Site 1121), Tomsk, Tomskaya Oblast
Institut Catala d Oncologia Badalona ( Site 1201), Badalona, Barcelona
Complejo Hospitalario Universitario A Coruna. CHUAC ( Site 1202), A Coruna, La Coruna
Instituto Valenciano de Oncologia - IVO ( Site 1205), Valencia, Valenciana, Comunitat
Hospital General Universitario de Valencia ( Site 1203), Valencia, Valenciana, Comunitat
Parc de Salut Mar ( Site 1200), Barcelona, Not set
Hospital Universitario Reina Sofia ( Site 1207), Cordoba, Not set
Hospital Clinico San Carlos ( Site 1209), Madrid, Not set
Hospital Materno Infantil [Malaga, Spain] ( Site 1208), Malaga, Not set
China Medical University Hospital ( Site 1903), Taichung, Not set
Taichung Veterans General Hospital ( Site 1902), Taichung, Not set
National Taiwan University Hospital ( Site 1904), Taipei, Not set
Taipei Veterans General Hospital ( Site 1900), Taipei, Not set
Linkou Chang Gung Memorial Hospital ( Site 1901), Taoyuan, Not set
Baskent Universitesi Adana Uygulama ve Arastirma Hastanesi ( Site 1303), Adana, Not set
Cukurova Uni. Tip Fakultesi ( Site 1302), Adana, Not set
Gazi Universitesi Tip Fakultesi ( Site 1308), Ankara, Not set
Baskent Universitesi Ankara Hastanesi ( Site 1300), Ankara, Not set
Akdeniz Universitesi Tıp Fakultesi ( Site 1301), Antalya, Not set
Uludag Universitesi Tip Fakultesi ( Site 1307), Bursa, Not set
Clinical oncology dispensary of Dnipro ( Site 1512), Dnipro, Dnipropetrovska Oblast
City Clinical Hosp.4 of DCC ( Site 1501), Dnipro, Dnipropetrovska Oblast
MI Precarpathian Clinical Oncology Center ( Site 1503), Ivano-Frankivsk, Ivano-Frankivska Oblast
Grigoriev Institute for medical Radiology NAMS of Ukraine ( Site 1511), Kharkiv, Kharkivska Oblast
Communal non profit enterprise Regional Clinical Oncology Center ( Site 1509), Kharkiv, Kharkivska Oblast
Khmelnitskiy Regional Onkology Dispensary ( Site 1513), Khmelnitskiy, Khmelnytska Oblast
Medical Center Asklepion LLC ( Site 1514), Khodosivka, Kyivska Oblast
National Cancer Institute of the MoH of Ukraine ( Site 1510), Kyiv, Kyivska Oblast
Medical and Diagnostic Centre LLC Dobryi Prognoz ( Site 1507), Kyiv, Kyivska Oblast
MI Odessa Regional Oncological Centre ( Site 1504), Odesa, Odeska Oblast
Kyiv City Clinical Oncology Centre ( Site 1505), Kyiv, Not set
Western General Hospital ( Site 1411), Edinburgh, Edinburgh, City Of
UCLH NHS Foundation Trust ( Site 1405), London, London, City Of
Mount Vernon Cancer Centre ( Site 1409), Northwood, London, City Of
Churchill Hospital ( Site 1406), Oxford, Oxfordshire
The James Cook University Hospital ( Site 1403), Middlesbrough, Not set
Northern Centre for Cancer Care ( Site 1408), Newcastle Upon Tyne, Not set
Conditions: Endometrial Neoplasms
A Phase 3 Randomized, Placebo-controlled Trial of Carboplatin and Paclitaxel With or Without Veliparib (ABT-888) in HER2-negative Metastatic or Locally Advanced Unresectable BRCA-associated Breast Cancer
Completed
The primary objective of the study is to assess the progression-free survival (PFS) of veliparib in combination with carboplatin and paclitaxel (C/P) compared to placebo plus C/P in participants with a Breast Cancer Gene 1 or 2 (BRCA1; BRCA2) mutation in Human Epidermal Growth Factor Receptor 2 (HER2)-negative metastatic or locally advanced unresectable breast cancer. The secondary objectives of the study are to assess overall survival (OS), clinical benefit rate (CBR) through the end of Week 24... Read More
The primary objective of the study is to assess the progression-free survival (PFS) of veliparib in combination with carboplatin and paclitaxel (C/P) compared to placebo plus C/P in participants with a Breast Cancer Gene 1 or 2 (BRCA1; BRCA2) mutation in Human Epidermal Growth Factor Receptor 2 (HER2)-negative metastatic or locally advanced unresectable breast cancer. The secondary objectives of the study are to assess overall survival (OS), clinical benefit rate (CBR) through the end of Week 24, objective response rate (ORR) and PFS on subsequent therapy (PFS2) in participants treated with veliparib in combination with C/P versus placebo in combination with C/P. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Banner MD Anderson Cancer Ctr /ID# 125011, Gilbert, Arizona +218 locations
Banner MD Anderson Cancer Ctr /ID# 125011, Gilbert, Arizona
University of Arkansas for Medical Sciences /ID# 124992, Little Rock, Arkansas
City of Hope /ID# 127117, Duarte, California
California Cancer Associates for Research & Excellence (cCARE) /ID# 136078, Fresno, California
Moores Cancer Center at UC San Diego /ID# 124991, La Jolla, California
Hematology and Oncology Assoc /ID# 130058, Newport Beach, California
Cancer Research Collaboration /ID# 128860, Santa Ana, California
Icri /Id# 128520, Whittier, California
Univ of Colorado Cancer Center /ID# 124983, Aurora, Colorado
Saint Joseph Hospital /ID# 131768, Denver, Colorado
Norwalk Hospital /ID# 133509, Norwalk, Connecticut
Lynn Cancer Institute, Boca /ID# 125013, Boca Raton, Florida
Holy Cross Hospital /ID# 125012, Fort Lauderdale, Florida
Sacred Heart Hospital /ID# 128279, Pensacola, Florida
Moffitt Cancer Center /ID# 124990, Tampa, Florida
Florida Cancer Specialists - East /ID# 125007, West Palm Beach, Florida
Emory Midtown Infectious Disease Clinic /ID# 133192, Atlanta, Georgia
The Cancer Ctr at DeKalb Med C /ID# 125024, Decatur, Georgia
University of Illinois - Chicago /ID# 127576, Chicago, Illinois
NorthShore University HealthSystem /ID# 124996, Evanston, Illinois
Midwestern Regional CTC /ID# 124986, Zion, Illinois
McFarland Clinic, PC /ID# 129904, Ames, Iowa
Johns Hopkins University /ID# 125015, Baltimore, Maryland
Baystate Medical Center /ID# 139461, Springfield, Massachusetts
UMass Chan Medical School /ID# 129067, Worcester, Massachusetts
Henry Ford Health System /ID# 134497, Detroit, Michigan
Spectrum Health Medical Group /ID# 133568, Grand Rapids, Michigan
Spectrum Health Medical Group /ID# 148471, Grand Rapids, Michigan
William Beaumont Hospital /ID# 125019, Royal Oak, Michigan
Univ of Mississippi Med Ctr,US /ID# 131352, Jackson, Mississippi
St. Lukes Cancer Institute /ID# 125023, Kansas City, Missouri
Washington University-School of Medicine /ID# 127575, Saint Louis, Missouri
Nebraska Hematology Oncology /ID# 132711, Lincoln, Nebraska
Rutgers Cancer Institute of New Jersey /ID# 125017, New Brunswick, New Jersey
University of New Mexico /ID# 125349, Albuquerque, New Mexico
Beth Israel Medical Center /ID# 125001, New York, New York
Mount Sinai St. Luke's /ID# 125003, New York, New York
Mission Cancer Center /ID# 134248, Asheville, North Carolina
Duke Cancer Center /ID# 124999, Durham, North Carolina
The Ohio State University /ID# 125022, Columbus, Ohio
University of Toledo /ID# 134849, Toledo, Ohio
Oregon Health and Science University /ID# 134229, Portland, Oregon
Lehigh Valley Health Network /ID# 130059, Allentown, Pennsylvania
Lehigh Valley Hosp/Muhlenberg /ID# 130277, Bethlehem, Pennsylvania
Penn State University and Milton S. Hershey Medical Center /ID# 124997, Hershey, Pennsylvania
Allegheny General Hospital /ID# 135094, Pittsburgh, Pennsylvania
University of Pittsburgh MC /ID# 125005, Pittsburgh, Pennsylvania
Texas Health Physicians Group /ID# 137740, Arlington, Texas
University of Texas Southwestern Medical Center /ID# 124989, Dallas, Texas
University of Texas MD Anderson Cancer Center /ID# 125353, Houston, Texas
University of Vermont Medical Center /ID# 125350, Burlington, Vermont
Swedish Cancer Institute - Issaquah /ID# 131534, Issaquah, Washington
Swedish Cancer Institute - Edmonds /ID# 131549, Seattle, Washington
Swedish Medical Center /ID# 125021, Seattle, Washington
Swedish Cancer Insititute - Ballard /ID# 131548, Seattle, Washington
Northwest Medical Specialties - Tacoma /ID# 125344, Tacoma, Washington
COIBA Centro de Oncologia e Investigacion de Buenos Aires /ID# 124839, Berazategui, Buenos Aires
Clinica Pergamino /ID# 127158, Pergamino, Buenos Aires
Instituto de Oncoloia de Rosario /ID# 127157, Rosario, Santa Fe
Centro Oncologico Riojano Integral /ID# 127938, La Rioja, Not set
St George Hospital /ID# 129416, Kogarah, New South Wales
Duplicate_The Prince of Wales Hospital /ID# 124845, Randwick, New South Wales
Southern Medical Day Care Centre /ID# 124844, Wollongong, New South Wales
Townsville University Hospital /ID# 126731, Douglas, Queensland
Duplicate_Flinders Centre for Innovation /ID# 127535, Bedford Park, South Australia
Royal Hobart Hospital /ID# 124849, Hobart, Tasmania
The Royal Melbourne Hospital /ID# 124846, Parkville, Victoria
Hollywood Private Hospital /ID# 124843, Nedlands, Western Australia
Ordensklinikum Linz GmbH Elisabethinen /ID# 126185, Linz, Oberoesterreich
Medizinische Universitaet Graz /ID# 126450, Graz, Steiermark
Medizinische Universitaet Wien /ID# 126184, Vienna, Wien
Landeskrankenhaus Salzburg-Universitätsklinikum der PMU (LKH) /ID# 126449, Salzburg, Not set
Bobruysk Interdistrict Onco. /ID# 137729, Bobruisk, Not set
State Institution Republican Scientific Practical Center of Oncology and Medical /ID# 125223, Minsk, Not set
Duplicate_Mogilev Reg Clin Oncology Dis /ID# 137728, Mogilev, Not set
Vitebsk Regional Clinical Oncology Dispensary /ID# 125219, Vitebsk, Not set
Universitair Ziekenhuis Antwerpen /ID# 124977, Edegem, Antwerpen
UCL Saint-Luc /ID# 124976, Woluwe-Saint-Lambert, Bruxelles-Capitale
Grand Hôpital de Charleroi /ID# 124981, Charleroi, Hainaut
Universitair Ziekenhuis Leuven /ID# 124980, Leuven, Vlaams-Brabant
Duplicate_AZ St-Jan Brugge-Oostende AV /ID# 124975, Brugge, West-Vlaanderen
ZNA Middelheim /ID# 124978, Antwerp, Not set
CHU UCL Namur - Sainte Elisabeth /ID# 124979, Namur, Not set
Duplicate_Sunnybrook Health Sciences Ctr /ID# 124882, Toronto, Ontario
Duplicate_Jewish General Hospital /ID# 124880, Montreal, Quebec
CHUM - Notre-Dame Hospital /ID# 124879, Montréal, Quebec
Duplicate_CHUQ-Hospital St. Sacrement /ID# 124881, Quebec City, Quebec
Hospital Clinico Vina del Mar /ID# 130100, Vina Del Mar, Valparaíso
Hospital Clinico Vina del Mar /ID# 148502, Vina Del Mar, Valparaíso
Instituto Nacional del Cancer /ID# 129343, Santiago, Not set
ICOS - Inst Clinic Oncology /ID# 125236, Temuco, Not set
Hospital Pablo Tobon Uribe /ID# 126657, Medellín, Antioquia
Instituto Medico de Alta Tecnologia Oncomédica S.A /ID# 129211, Monteria, Cordoba
Administradora del Country_S.A-Clinica Del Country /ID# 125255, Bogota, Cundinamarca
Hospital Univ San Ignacio /ID# 126655, Bogota, Cundinamarca
Centro Medico Imbanaco de Cali /ID# 126656, Cali, Not set
Fakultni Nemocnice Brno /ID# 128176, Brno, Not set
Masarykuv onkologicky ustav /ID# 124886, Brno, Not set
Duplicate_FN Hradec Kralove /ID# 127080, Hradec Kralove, Not set
Fakultni nemocnice Olomouc /ID# 124885, Olomouc, Not set
Vseobecna fakultni nemocnice v Praze /ID# 124887, Praha, Not set
Rigshospitalet /ID# 124891, Copenhagen Ø, Hovedstaden
Sygehus Lillebælt, Vejle /ID# 124892, Vejle, Syddanmark
East Tallinn Central Hospital /ID# 126475, Kesklinna Linnaosa, Harjumaa
Docrates Cancer Center /ID# 124896, Helsinki, Not set
Duplicate_Helsinki Univ Central Hospital /ID# 124897, Helsinki, Not set
Duplicate_Tampere University Hospital /ID# 124898, Tampere, Not set
Vaasa Central Hospital /ID# 132548, Vaasa, Not set
Institut Paoli-Calmettes /ID# 124903, Marseille, Bouches-du-Rhone
Institut Curie /ID# 124902, Paris CEDEX 05, Ile-de-France
Institut de Cancérologie de l'Ouest René Gauducheau /ID# 137726, St Herblain CEDEX, Loire-Atlantique
Institut Curie - site CLCC René Huguenin /ID# 124904, Saint-cloud, Not set
Universitaetsklinik Heidelberg /ID# 126664, Heidelberg, Baden-Wuerttemberg
Universitaetsklinimum Tuebingen /ID# 129968, Tubingen, Baden-Wuerttemberg
Universitaetsklinikum Ulm /ID# 135230, Ulm, Baden-Wuerttemberg
Universitaetsklinikum Koeln /ID# 126905, Köln, Nordrhein-Westfalen
Universitaetsklinikum Carl Gustav Carus an der TU Dresden /ID# 127180, Dresden, Not set
Klinikum rechts der Isar - Technische Universitaet Muenchen /ID# 125256, Munich, Not set
Sana Klinikum Offenbach /ID# 126733, Offenbach am Main, Not set
Semmelweis Egyetem /ID# 132485, Budapest, Not set
Pecsi Tudomanyegyetem Klinikai Kozpont /ID# 125259, Pecs, Not set
Jasz-Nagykun-Szolnok Megyei Hetenyi Geza Korhaz /ID# 124911, Szolnok, Not set
Duplicate_Zala Megyei Korhaz /ID# 131341, Zalaegerszeg, Not set
The Chaim Sheba Medical Center /ID# 124918, Ramat Gan, Tel-Aviv
Tel Aviv Sourasky Medical Center /ID# 130276, Tel Aviv-Yafo, Tel-Aviv
Duplicate_Soroka University Medical Center /ID# 124917, Be'er Sheva, Not set
Assaf Harofeh Medical Center /ID# 124915, Be'Er Ya'Akov, Not set
Rambam Health Care Campus /ID# 124916, Haifa, Not set
Shaare Zedek Medical Center /ID# 130275, Jerusalem, Not set
Gastroenterology Institute, Division of Medicine /ID# 124919, Jerusalem, Not set
Kaplan Medical Center /ID# 124914, Rehovot, Not set
Ospedale San Raffaele IRCCS /ID# 125261, Milan, Lombardia
IEO -Istituto Europeo di Oncologia /ID# 125260, Milan, Milano
IRCCS Ospedale Sacro Cuore Don Calabria /ID# 125262, Negrar, Verona
Centro di Riferimento Oncologico /ID# 126738, Aviano, Not set
Grande Ospedale Metropolitano Bianchi Melacrino Morelli /ID# 125263, Reggio Calabria, Not set
National Cancer Center /ID# 125602, Goyang, Gyeonggido
Yonsei University Health System Severance Hospital /ID# 125599, Seoul, Seoul Teugbyeolsi
Korea University Anam Hospital /ID# 128968, Seoul, Not set
Seoul National University Hospital /ID# 125600, Seoul, Not set
Asan Medical Center /ID# 125601, Seoul, Not set
Samsung Medical Center /ID# 125598, Seoul, Not set
Pauls Stradins Clinical University Hospital /ID# 125264, Riga, Not set
Riga East Clinical University Hospital /ID# 125265, Riga, Not set
Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 125266, Kaunas, Not set
National Cancer Institute /ID# 125267, Vilnius, Not set
Centro de Estudios Clínicos Especializados /ID# 128680, Mérida, Yucatan
Centro Oncologico de Chihuahua /ID# 128679, Chihuahua, Not set
Instituto Nacional de Cancerología INCAN /ID# 128676, Ciudad de Mexico, Not set
Erasmus Medisch Centrum /ID# 124935, Rotterdam, Zuid-Holland
Universitair Medisch Centrum Groningen /ID# 129069, Groningen, Not set
Maastricht Universitair Medisch Centrum /ID# 129068, Maastricht, Not set
Haukeland University Hospital /ID# 150177, Bergen, Hordaland
Wojewodzki Szpital Specjalistyczny /ID# 127258, Wroclaw, Dolnoslaskie
Centrum Onkologii Lukaszczyka /ID# 124938, Bydgoszcz, Kujawsko-pomorskie
Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopern /ID# 126999, Lodz, Lodzkie
MRUK-MED I Spolka z ograniczona odpowiedzialnoscia /ID# 124939, Rzeszow, Podkarpackie
Wojewodzki Szpital Zespolony /ID# 126998, Elblag, Warminsko-mazurskie
Centro Hospitalar de Vila Nova de Gaia/Espinho, EPE /ID# 126510, Vila Nova De Gaia, Porto
Centro Hospitalar Universitário do Algarve, EPE - Hospital Faro /ID# 125298, Faro, Not set
Centro Hospitalar Universitário de Lisboa Norte, EPE - Hospital de Santa Maria /ID# 125299, Lisboa, Not set
Unidade Local de Saúde de Matosinhos, EPE /ID# 126511, Matosinhos, Not set
IPO Porto FG, EPE /ID# 125297, Porto, Not set
Centro Hospitalar Universitario de Sao Joao, EPE /ID# 126508, Porto, Not set
Ad-Vance Medical Research, LLC /ID# 126043, Ponce, Not set
San Juan Municipal Hospital /ID# 124695, San Juan, Not set
S.C. Centrul de Oncologie Sf. Nectarie S.R.L. /ID# 124948, Craiova, Dolj
Duplicate_lnstitutul Oncologic Prof Dr Alexandru Trestioreanu /ID# 124943, Bucharest, Not set
Spitalul Clinic Judetean de Urgenta Cluj -Napoca /ID# 124945, Cluj-Napoca, Not set
Oncomed SRL /ID# 127598, Timisoara, Not set
Sverdlovsk Regional Oncology Dispensary /ID# 130950, Yekaterinburg, Sverdlovskaya Oblast
Regional Oncology Dispensary /ID# 125936, Kursk, Tatarstan, Respublika
Duplicate_archangel Clinical Oncology /ID# 126031, Arkhangelsk, Not set
Altay Regional Oncological Dispesary /ID# 127160, Barnaul, Not set
Belgorod Oncology Dispensary /ID# 129315, Belgorod, Not set
Duplicate_Saratov State Medical University n.s. Chernyshevskiy /ID# 139395, Saratov, Not set
LLC BioEq Ltd. /ID# 134529, St. Petersburg, Not set
Siberian State Medical University /ID# 127161, Tomsk, Not set
Volgograd Regional Clinical Oncology Dispensary /ID# 124952, Volzhsky, Not set
National University Hospital /ID# 125315, Singapore, Not set
Johns Hopkins Singapore IMC /ID# 125316, Singapore, Not set
GVI Oncology /ID# 125321, Gqeberha, Eastern Cape
University of Free State, Universitas Annex (National Hospital Grounds) /ID# 128499, Bloemfontein, Free State
Wits Clinical Research Site /ID# 125317, Johannesburg, Gauteng
Medical Oncology Ctr Rosebank /ID# 125322, Johannesburg, Gauteng
Sandton Oncology Medical Group PTY Ltd /ID# 125323, Johannesburg, Gauteng
Mary Potter Oncology Centre /ID# 133269, Pretoria, Gauteng
The Oncology Centre /ID# 126104, Durban, Kwazulu-Natal
Netcare Oncology Intervent Ctr /ID# 125320, Cape Town, Western Cape
Cancercare Outeniqua Oncology Centre /ID# 125319, George, Western Cape
Hospital Santa Creu i Sant Pau /ID# 124963, Barcelona, Not set
Hospital General Universitario Gregorio Maranon /ID# 124962, Madrid, Not set
Hospital Universitario HM Sanchinarro /ID# 124960, Madrid, Not set
Hospital Universitario Virgen de la Victoria /ID# 124961, Malaga, Not set
Hospital Clinico Universitario de Valencia /ID# 124959, Valencia, Not set
Skane University hospital /ID# 124966, Malmo, Skane Lan
Norrlands University hospital /ID# 124967, Umea, Vasterbottens Lan
Sahlgrenska University Hospital /ID# 124965, Gothenburg, Vastra Gotalands Lan
Linkoping University Hospital /ID# 126795, Linkoping, Not set
Duplicate_Karolinska Univ Sjukhuset /ID# 124964, Solna, Not set
Uppsala University Hospital /ID# 126512, Uppsala, Not set
Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 125575, Kaohsiung, Not set
National Taiwan University Hospital /ID# 125324, Taipei City, Not set
Hacettepe University Faculty of Medicine /ID# 125336, Ankara, Not set
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi /ID# 125337, Ankara, Not set
Duplicate_Akdeniz University Medical Fac /ID# 125339, Antalya, Not set
Bezmi Alem Univ Med Fac Hosp /ID# 127901, Istanbul, Not set
Istanbul University Istanbul Medical Faculty /ID# 145144, Istanbul, Not set
Municipal Non-Profit Enterprise City Clinical Hospital No.4 of Dnipro City Counc /ID# 124968, Dnipro, Not set
Donetsk Regional Antitumor Ctr /ID# 124970, Donetsk, Not set
Communal non-profit enterprise Regional Center of Oncology /ID# 124972, Kharkiv, Not set
Lviv Oncological Regional Therapeutical and Diagnostic Centre /ID# 124974, Lviv, Not set
Poltava Regional Clinical Oncology Centre of Poltava Regional Council /ID# 124969, Poltava, Not set
Zaporizhzhia Med. Academy MOH /ID# 129800, Zaporizhia, Not set
ME Kryviy Rih Oncology Dispensary /ID# 129806, Кривий Ріг, Not set
University Hospitals Bristol /ID# 128343, Bristol, Bristol, City Of
Hull University Teaching Hospitals NHS Trust /ID# 133030, Hull, East Riding Of Yorkshire
Nottingham University Hospitals NHS Trust /ID# 125340, Nottingham, Nottinghamshire
University Hospitals Birmingham NHS Foundation Trust /ID# 125342, Birmingham, Not set
Conditions: Metastatic Breast Cancer
The BURAN Study of Buparlisib in Patients With Recurrent or Metastatic HNSCC
Active Not Recruiting
The BURAN study is a randomized, open-label phase III study to assess the treatment effect of once-daily buparlisib in combination with weekly paclitaxel compared to weekly paclitaxel alone in patients with refractory, recurrent, or metastatic head and neck squamous cell carcinoma (HNSCC) that have progressed after prior anti PD 1/anti PD L1 monotherapy; prior anti PD 1/anti PD L1 therapy in combination with platinum-based therapy; or after sequential treatment of anti PD 1/anti PD L1 therapy, e... Read More
The BURAN study is a randomized, open-label phase III study to assess the treatment effect of once-daily buparlisib in combination with weekly paclitaxel compared to weekly paclitaxel alone in patients with refractory, recurrent, or metastatic head and neck squamous cell carcinoma (HNSCC) that have progressed after prior anti PD 1/anti PD L1 monotherapy; prior anti PD 1/anti PD L1 therapy in combination with platinum-based therapy; or after sequential treatment of anti PD 1/anti PD L1 therapy, either prior to or post, platinum-based therapy. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: City of Hope, Duarte, California +161 locations
City of Hope, Duarte, California
Yale University, Yale Cancer Center, New Haven, Connecticut
Moffitt Cancer Center, Tampa, Florida
Emory University, Atlanta, Georgia
Northwestern University, Chicago, Illinois
University of Kentucky, Lexington, Kentucky
Norton Cancer Institute, Louisville, Kentucky
University of Michigan, Ann Arbor, Michigan
Karmanos Cancer Institute, Detroit, Michigan
Henry Ford Health System, Detroit, Michigan
Washington University School of Medicine, Saint Louis, Missouri
Montefiore Medical Center, Bronx, New York
NYU Langone, New York, New York
Stony Brook University Medical Center, Stony Brook, New York
Duke University Medical Center, Durham, North Carolina
University of Cincinnati Cancer Center, Cincinnati, Ohio
Fox Chase Cancer Center, Philadelphia, Pennsylvania
UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania
Hollings Cancer Center, Charleston, South Carolina
West Cancer Center, Germantown, Tennessee
Hope Cancer Center, UT Health East Texas, Tyler, Texas
Fundacion Cenit para la Investigacion en Neurociencias, Buenos Aires, Not set
Centro de Investigacion Pergamino SA - Clinica Pergamino S.A., Buenos Aires, Not set
Instituto de Investigaciones Metabólicas (IDIM) // Instituto de Investigaciones Metabólicas S.A., Ciudad Autonoma de Buenos Aire, Not set
IONC SRL- Instituto Oncológico de Córdoba, Córdoba, Not set
Fundacion CORI para la Investigacion y Prevencion del Cáncer, La Rioja, Not set
Centro para la Atencion Integral del Paciente Oncologico - CAIPO, Tucuman, Not set
Princess Alexandra Hospital, Brisbane, Not set
Universitair Ziekenhuis Gent UZ Gent, Ghent, Not set
Universitair Ziekenhuis Brussel, Jette, Not set
Clinique CHC MontLégia, Liege, Not set
Clinique Saint-Pierre dOttignies CSPO, Ottignies, Not set
CHUM, Montreal, Not set
CancerCare Manitoba, Winnipeg, Not set
Beijing Tongren Hospital, Beijing, Not set
The First Affiliated Hospital of Bengbu Medical College, Bengbu, Not set
Hunan Cancer Hospital, Changsha, Not set
Xiangya Hospital Central South University, Changsha, Not set
Sichuan Cancer Hospital, Chengdu, Not set
Affiliated Cancer Hospital of Chongqing University, Chongqing, Not set
The First Affiliated Hospital of CQMU, Chongqing, Not set
Sun Yat-sen University Cancer Center, Guangzhou, Not set
Affiliated Cancer Hospital of Guangzhou Medical University, Guangzhou, Not set
Zhejiang Cancer Hospital, Hangzhou, Not set
Anhui Provincial Cancer Hospital, Hefei, Not set
Shandong Provincial Tumor Hospital, Jinan, Not set
Yunnan Cancer Hospital, Kunming, Not set
Cancer Hospital affiliated to Guangxi Medical University, Naning, Not set
Shanghai Dongfang Hospital, Shanghai, Not set
Tianjin Cancer Hospital, Tianjin, Not set
Henan Cancer Hospital, Zhengzhou, Not set
The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Not set
Centre hospitalier Universitaire de Bordeaux, Bordeaux, Not set
Centre Franois Baclesse, Caen, Not set
Centre Leon Berard, Lyon, Not set
Hopital de la Timone, Marseille, Not set
Institut regional du Cancer de Montpellier, Montpellier, Not set
LHopital prive du Confluent Nantes, Nantes, Not set
Clinique Hartmann, Neuilly Sur Seine, Not set
Hôpital St-Louis, Paris, Not set
Hopital La Pitie Salpetriere, Paris, Not set
Hopital Tenon, Paris, Not set
CHP Saint-Grégoire, Saint-Grégoire, Not set
Institut de cancerologie de Lorraine, Vandœuvre-lès-Nancy, Not set
Uniklinik RWTH Aachen, Aachen, Not set
Universitaetsklinikum Bonn, Bonn, Not set
University Hospital Essen, Essen, Not set
Franziskus Hospital, Georgsmarienhütte, Not set
HNO-Klinik des Universitats-Klinikums Giessen, Giessen, Not set
Universitatsmedizin Greifswald - KoR, Greifswald, Not set
Universitatsklinikum Hamburg Eppendorf, Hamburg, Not set
Marienkrankenhaus Hamburg, Hamburg, Not set
Hannover Medical School, Hannover, Not set
Universitatsklinikum Leipzig, Leipzig, Not set
UNIVERSITÄTSMEDIZIN Mainz III. Klinik/Poliklinik, Mainz, Not set
Queen Mary Hospital, Hong Kong, Not set
Orszagos Onkologiai Intezet, Budapest, Not set
University of Pecs Department of Oncotherapy, Pécs, Not set
Tolna Megyei Balassa Janos Korhaz, Szekszárd, Not set
Azienda Ospedaliera Universitaria S.Orsola-Malpighi, Bologna, Not set
ASST Spedali Civili Brescia, Brescia, Not set
Istituto di Candiolo IRCCS, Candiolo, Not set
IRCCS - Istituto Scientifico Romagnolo per la Cura e lo Studio dei Tumori, Cesena, Not set
A.O. S. Croce e Carle, Cuneo, Not set
Azienda Ospedaliero Universitaria Careggi - Firenze, Firenze, Not set
Azienda Ospedaliera San Paolo Polo Universitario, Milano, Not set
Istituto Nazionale dei Tumori, Milan, Not set
INT IRCCS Fondazione G.Pascale, Napoli, Not set
A.O.U. "Maggiore della Carita"- S.C.D.U Oncologiac, Novara, Not set
Azienda Ospedaliero Universitaria Policlinico "Paolo Giaccone" U.O.C. Oncologia Medica, Palermo, Not set
Azienda Ospedaliero Universitaria di Parma, Parma, Not set
IRCCS Maugeri Pavia, Pavia, Not set
IRCCS Istituto Clinico Humanitas, Rozzano, Not set
AOU San Giovanni di Dio e Ruggi D'Aragona, Università degli Studi di Salerno, Salerno, Not set
Azienda Ospedaliera Universitaria Senese Policlinico Le Scotte, Siena, Not set
ASST Valtellina e Alto Lario - UOC Oncologia Medica Ospedale di Sondrio, Sondrio, Not set
AO Card. G. Panico, Tricase, Not set
Azienda Sanitaria Universitaria Integrata di Udine, Udine, Not set
Azienda Ospedaliera Universitaria Integrata Verona, Verona, Not set
Hyogo Cancer Center, Akashi-shi, Not set
National Cancer Center Hospital, Chuo Ku, Not set
Kyushu University Hospital, Fukuoka shi, Not set
Saitama Medical University International Medical Center, Hidaka, Not set
Kagawa University Hospital, Kita-gun, Not set
Kobe University Hospital, Kobe, Not set
The Cancer Institute Hospital of JFCR, Koto-Ku, Not set
National Hospital Organization Shikoku Cancer Center, Matsuyama, Not set
Aichi Cancer Center, Nagoya, Not set
Kindai University Hospital, Osaka Sayama-shi, Not set
Hokkaido University Hospital, Sapporo, Not set
National University Corporation Tohoku University, Tohoku University Hospital, Sendai, Not set
Showa University Hospital, Shinagawa-Ku, Not set
Shizuoka Cancer Center, Shizuoka, Not set
Kosin University Gospel Hospital, Busan, Not set
Gachon University Gil Medical Center, Incheon, Not set
Seoul National University Bundang Hospital, Seongnam-si, Not set
Korea University Anam Hospital, Seoul, Not set
Asan Medical Center, Seoul, Not set
The Catholic University of Korea Seoul ST. Mary's Hospital, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
Ajou University Hospital, Suwon-si, Not set
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie, Gliwice, Not set
Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie, Warszawa, Not set
Fundacion Oncologico de Galicia Jos Antonio Quiroga y Pieyro, A Coruña, Not set
Institut Catala d Oncologia Badalona, Badalona, Not set
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
Vall dHebron Institute of Oncology (VHIO), Barcelona, Not set
Hospital Clinic Barcelona, Barcelona, Not set
Hospital Universitario de Burgos, Burgos, Not set
Hospital Reina Sofia, Córdoba, Not set
Hospital Duran i Reynals - Institut Catala dOncologia ICO, Hospitalet de Llobregat, Not set
Complejo Hospitalario de Jaen, Jaén, Not set
Hospital Universitario Severo Ochoa, Leganés, Not set
Hospital Universitario Lucus Augusti, Lugo, Not set
Clinica Universidad de Navarra, Madrid, Not set
Hospital Universitario Ramon y Cajal, Madrid, Not set
Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Hospital Clinico Universitario Virgen de la Arrixaca, Madrid, Not set
Hospital General Universitario Gregorio Maran, Madrid, Not set
Hospital Puerta de Hierro- Majadahonda, Majadahonda, Not set
Hospital Regional de Malaga, Málaga, Not set
Hospital de Navarra, Pamplona, Not set
Hospital Universitario Marques de Valdecilla, Santander, Not set
Hospital Universitario Santiago de Compostela, Santiago De Compostela, Not set
Valme Hospital Medical Oncology Department, Sevilla, Not set
Instituto Valenciano de Oncologia, Valencia, Not set
Hospital Clinico Universitario Valencia - INCLIVA, Valencia, Not set
Hospital Universitario Miguel Servet, Zaragoza, Not set
Changhua Christian Hospital, Changhua, Not set
Chang Gung Memorial Hospital-KaohSiung, Kaohsiung, Not set
Taichung Veterans General Hospital, Taichung, Not set
National Cheng Kung University Hospital, Tainan, Not set
Chi Mei Medical Center Liouying, Tainan, Not set
Taipei Veterans General Hospital, Taipei, Not set
Chang Gung Memorial Hospital-LinKou, Taoyuan, Not set
Edinburgh Cancer Center, Edinburgh, Not set
Beatson Oncology Centre, Glasgow, Not set
University College London Hospitals, London, Not set
The Royal Marsden NHS Foundation Trust, London, Not set
The Royal Marsden NHS Foundation Trust - Sutton, Sutton, Not set
Conditions: Head and Neck Cancer
A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer
Active Not Recruiting
DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with other anti-cancer agents in patients with HER2-positive Metastatic Breast Cancer
DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with other anti-cancer agents in patients with HER2-positive Metastatic Breast Cancer Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: Research Site, Fort Myers, Florida +71 locations
Research Site, Fort Myers, Florida
Research Site, Saint Petersburg, Florida
Research Site, Commack, New York
Research Site, Harrison, New York
Research Site, New York, New York
Research Site, New York, New York
Research Site, Columbus, Ohio
Research Site, Nashville, Tennessee
Research Site, Fort Worth, Texas
Research Site, Fairfax, Virginia
Research Site, Melbourne, Not set
Research Site, Barretos, Not set
Research Site, Belo Horizonte, Not set
Research Site, Natal, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Rio de Janeiro, Not set
Research Site, Sao Paulo, Not set
Research Site, Sao Paulo, Not set
Research Site, Sorocaba, Not set
Research Site, Montreal, Quebec
Research Site, Quebec, Not set
Research Site, Toronto, Not set
Research Site, Villejuif Cedex, Not set
Research Site, München, Not set
Research Site, Würzburg, Not set
Research Site, Delhi, Not set
Research Site, Gurgaon, Not set
Research Site, Madurai, Not set
Research Site, Mumbai, Not set
Research Site, Bologna, Not set
Research Site, Milan, Not set
Research Site, Napoli, Not set
Research Site, Rome, Not set
Research Site, Busan-si, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Bydgoszcz, Not set
Research Site, Koszalin, Not set
Research Site, Lublin, Not set
Research Site, Łódź, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Saint Petersburg, Not set
Research Site, Sankt-Peterburg, Not set
Research Site, Sankt-Peterburg, Not set
Research Site, Barcelona, Not set
Research Site, L'Hospitalet de Llobregat, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Sevilla, Not set
Research Site, Hualien, Not set
Research Site, Tainan, Not set
Research Site, Taipei City, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taoyuan City, Not set
Research Site, Ankara, Not set
Research Site, Edirne, Not set
Research Site, Istanbul, Not set
Research Site, Istanbul, Not set
Research Site, Izmir, Not set
Research Site, Buckhurst Hill, Not set
Conditions: Metastatic Breast Cancer
Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected
Active Not Recruiting
The objective of this study is to assess the efficacy and safety of the combination of alpelisib and olaparib compared with single agent cytotoxic chemotherapy in patients with platinum resistant or refractory high-grade serous ovarian cancer, with no germline BRCA mutation detected.
The objective of this study is to assess the efficacy and safety of the combination of alpelisib and olaparib compared with single agent cytotoxic chemotherapy in patients with platinum resistant or refractory high-grade serous ovarian cancer, with no germline BRCA mutation detected. Read Less
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
02/10/2025
Locations: Arizona Oncology Associates, Phoenix, Arizona +92 locations
Arizona Oncology Associates, Phoenix, Arizona
HonorHealth, Phoenix, Arizona
Florida Cancer Specialists, Fort Myers, Florida
Florida Cancer Specialists, West Palm Beach, Florida
Maryland Oncology Hematology P A, Silver Spring, Maryland
Massachusetts General Hospital, Boston, Massachusetts
Dana Farber Cancer Institute, Boston, Massachusetts
Memorial Sloan Kettering Cancer Ctr, New York, New York
Oncology Hematology Care Inc, Cincinnati, Ohio
University Of Cincinnati, Cincinnati, Ohio
Avera Cancer Institute, Sioux Falls, South Dakota
Sarah Cannon Research Institute, Nashville, Tennessee
Texas Oncology P A, Bedford, Texas
Texas Oncology, Dallas, Texas
Texas Oncology P A, San Antonio, Texas
Texas Oncology Northeast Texas, Tyler, Texas
Novartis Investigative Site, Caba, Buenos Aires
Novartis Investigative Site, Ciudad Autonoma de Bs As, Buenos Aires
Novartis Investigative Site, Buenos Aires, Not set
Novartis Investigative Site, Bedford Park, South Australia
Novartis Investigative Site, Shepparton, Victoria
Novartis Investigative Site, Sydney, Not set
Novartis Investigative Site, Innsbruck, Tyrol
Novartis Investigative Site, Graz, Not set
Novartis Investigative Site, Bruxelles, Not set
Novartis Investigative Site, Leuven, Not set
Novartis Investigative Site, Namur, Not set
Novartis Investigative Site, Belo Horizonte, Minas Gerais
Novartis Investigative Site, Sao Paulo, SP
Novartis Investigative Site, Calgary, Alberta
Novartis Investigative Site, Vancouver, British Columbia
Novartis Investigative Site, London, Ontario
Novartis Investigative Site, Toronto, Ontario
Novartis Investigative Site, Chengdu, Sichuan
Novartis Investigative Site, Beijing, Not set
Novartis Investigative Site, Jinan, Not set
Novartis Investigative Site, Shanghai, Not set
Novartis Investigative Site, Tianjin, Not set
Novartis Investigative Site, Novy Jicin, Czech Republic
Novartis Investigative Site, Ostrava, Poruba
Novartis Investigative Site, Praha, Not set
Novartis Investigative Site, Herlev, Not set
Novartis Investigative Site, Odense C, Not set
Novartis Investigative Site, Kuopio, Not set
Novartis Investigative Site, Tampere, Not set
Novartis Investigative Site, Turku, Not set
Novartis Investigative Site, Besancon Cedex, Not set
Novartis Investigative Site, Lyon, Not set
Novartis Investigative Site, Paris, Not set
Novartis Investigative Site, Pierre Benite, Not set
Novartis Investigative Site, Villejuif, Not set
Novartis Investigative Site, Mannheim, Baden Wuerttemberg
Novartis Investigative Site, Berlin, Not set
Novartis Investigative Site, Dresden, Not set
Novartis Investigative Site, Essen, Not set
Novartis Investigative Site, Bologna, BO
Novartis Investigative Site, Firenze, FI
Novartis Investigative Site, Milano, MI
Novartis Investigative Site, Milano, MI
Novartis Investigative Site, Roma, RM
Novartis Investigative Site, Vicenza, VI
Novartis Investigative Site, Napoli, Not set
Novartis Investigative Site, Seoul, Not set
Novartis Investigative Site, Seoul, Not set
Novartis Investigative Site, Kota Kinabalu, Sabah
Novartis Investigative Site, Kuching, Sarawak
Novartis Investigative Site, Kuala Lumpur, Wilayah Persekutuan
Novartis Investigative Site, Kuala Lumpur, Not set
Novartis Investigative Site, Monterrey, Nuevo Leon
Novartis Investigative Site, Ciudad de Mexico, Not set
Novartis Investigative Site, Eindhoven, Not set
Novartis Investigative Site, Loures, Not set
Novartis Investigative Site, Porto, Not set
Novartis Investigative Site, Arkhangelsk, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Bratislava, Slovak Republic
Novartis Investigative Site, Cordoba, Andalucia
Novartis Investigative Site, Barcelona, Catalunya
Novartis Investigative Site, Barcelona, Catalunya
Novartis Investigative Site, Valencia, Comunidad Valenciana
Novartis Investigative Site, Pamplona, Navarra
Novartis Investigative Site, Madrid, Not set
Novartis Investigative Site, Taichung, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Adana, Not set
Novartis Investigative Site, Ankara, Not set
Novartis Investigative Site, Ankara, Not set
Novartis Investigative Site, Izmir, Not set
Novartis Investigative Site, Glasgow, Not set
Novartis Investigative Site, London, Not set
Novartis Investigative Site, Manchester, Not set
Conditions: Ovarian Cancer
Study of Pembrolizumab/Vibostolimab Coformulation (MK-7684A) in Combination With Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (MK-7684A-007/KEYVIBE-007)
Active Not Recruiting
The primary hypothesis is that pembrolizumab/vibostolimab (MK-7684A) in combination with chemotherapy is superior to pembrolizumab in combination with chemotherapy with respect to overall survival (OS) in treatment-naïve metastatic participants with non-small cell lung cancer (NSCLC).
The primary hypothesis is that pembrolizumab/vibostolimab (MK-7684A) in combination with chemotherapy is superior to pembrolizumab in combination with chemotherapy with respect to overall survival (OS) in treatment-naïve metastatic participants with non-small cell lung cancer (NSCLC). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/07/2025
Locations: UCHealth Memorial Hospital-Heme Onc ( Site 0003), Colorado Springs, Colorado +148 locations
UCHealth Memorial Hospital-Heme Onc ( Site 0003), Colorado Springs, Colorado
University of Colorado Health - Harmony-Cancer Care and Hematology - Ft. Collins ( Site 0031), Fort Collins, Colorado
Mayo Clinic in Florida ( Site 0022), Jacksonville, Florida
Mount Sinai Hospital ( Site 0011), Chicago, Illinois
University of Chicago Medical Center ( Site 0015), Chicago, Illinois
New England Cancer Specialists ( Site 0008), Scarborough, Maine
Cancer and Hematology Centers of Western Michigan ( Site 0002), Grand Rapids, Michigan
Mayo Clinic in Rochester, Minnesota ( Site 0030), Rochester, Minnesota
Stony Brook University-Cancer Center ( Site 0013), Stony Brook, New York
Lancaster General Hospital - Ann B Barshinger Cancer Institute ( Site 0012), Lancaster, Pennsylvania
Charleston Oncology ( Site 0019), Charleston, South Carolina
University of Virginia Cancer Center ( Site 0018), Charlottesville, Virginia
Centro de Oncología e Investigación de Buenos Aires ( Site 0203), Berazategui, Buenos Aires
Instituto de Investigaciones Clínicas Mar del Plata ( Site 0204), Mar del Plata, Buenos Aires
Hospital Italiano de Buenos Aires-Clinical Oncology ( Site 0209), ABB, Caba
Centro de Educación Médica e Investigaciones Clínicas (CEMIC)-Medical Oncology ( Site 0202), Buenos Aires, Caba
Sanatorio Parque ( Site 0205), Rosario, Santa Fe
Hospital Provincial del Centenario ( Site 0212), Rosario, Santa Fe
Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0206), La Rioja, Not set
Ordensklinikum Linz GmbH Elisabethinen-Department of Pneumology ( Site 0705), Linz, Oberosterreich
Kepler Universitätsklinikum ( Site 0707), Linz, Oberosterreich
Medizinische Universität Graz ( Site 0704), Graz, Steiermark
Medizinische Universitaet Innsbruck ( Site 0703), Innsbruck, Tirol
Klinik Penzing-2. Lungenabteilung ( Site 0702), Vienna, Wien
Klinik Floridsdorf-Abteilung für Innere Medizin und Pneumologie ( Site 0701), Wien, Not set
Liga Norte Riograndense Contra o Câncer-Centro de Pesquisa Clínica ( Site 0403), Natal, Rio Grande Do Norte
Hospital Nossa Senhora da Conceição-Centro Integrado de Pesquisa em Oncologia ( Site 0405), Porto Alegre, Rio Grande Do Sul
Clínica de Oncologia Reichow ( Site 0407), Blumenau, Santa Catarina
Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA ( Site 0406), Rio de Janeiro, Not set
Hospital Paulistano ( Site 0401), Sao Paulo, Not set
James Lind Centro de Investigación del Cáncer ( Site 0502), Temuco, Araucania
CIDO SpA-Oncology ( Site 0508), Temuco, Araucania
Biocenter ( Site 0514), Concepción, Biobio
FALP-UIDO ( Site 0505), Santiago, Region M. De Santiago
Centro de Oncología de Precisión ( Site 0515), Santiago, Region M. De Santiago
Bradfordhill ( Site 0510), Santiago, Region M. De Santiago
ONCOCENTRO APYS-ACEREY ( Site 0503), Viña del Mar, Valparaiso
Centro de Investigación Oncológica del Norte ( Site 0504), Antofagasta, Not set
Anhui Provincil Hospital South District-Respiratory Medicine Dept ( Site 2619), Hefei, Anhui
Beijing Cancer hospital-Thoracic Cancer Department A ( Site 2602), Beijing, Beijing
Fujian Provincial Cancer Hospital-oncology department ( Site 2621), Fuzhou, Fujian
The First Affiliated hospital of Xiamen University ( Site 2626), Xiamen City, Fujian
Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine (, Guangzhou, Guangdong
Harbin Medical University Cancer Hospital-oncology of department ( Site 2604), Harbin, Heilongjiang
Henan Cancer Hospital ( Site 2608), Zhengzhou, Henan
Wuhan Union Hospital Cancer Center-Cancer Center ( Site 2618), Wuhan, Hubei
Tongji Hospital Tongji Medical,Science & Technology ( Site 2617), Wuhan, Hubei
Xiangya Hospital Central South University-Oncology department ( Site 2627), Changsha, Hunan
The Second Xiangya Hospital of Central South University ( Site 2623), Changsha, Hunan
Hunan Cancer Hospital ( Site 2622), Changsha, Hunan
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Oncology (, Nanjing, Jiangsu
The First Affiliated Hospital of Nanchang University-Respiratory Medicine Department ( Site 2625), Nanchang, Jiangxi
The Second Affiliated Hospital of Nanchang University-Oncology Department ( Site 2624), Nanchang, Jiangxi
Jilin Cancer Hospital-oncology department ( Site 2603), Changchun, Jilin
The First Affiliated Hospital of Xi'an Jiaotong University-Oncology ( Site 2607), Xi'an, Shaanxi
Shandong Cancer Hospital-Oncology Department ( Site 2630), Jinan, Shandong
Fudan University Shanghai Cancer Center ( Site 2616), Shanghai, Shanghai
Shanghai Pulmonary Hospital-Oncology Department ( Site 2601), Shanghai, Shanghai
West China Hospital of Sichuan University ( Site 2610), Cheng Du, Sichuan
Sichuan Cancer hospital ( Site 2628), Chengdu, Sichuan
The Second People's Hospital of Yibin ( Site 2629), Yibin, Sichuan
Tianjin Medical University Cancer Institute and Hospital-lung cancer ( Site 2606), Tianjin, Tianjin
The First Affiliated Hospital, Zhejiang University-Respiratory Department ( Site 2613), Hangzhou, Zhejiang
Sir Run Run Shaw Hospital-Medical Oncology ( Site 2615), Hangzhou, Zhejiang
Zhejiang Cancer Hospital-Oncology ( Site 2612), Hangzhou, Zhejiang
The Second Affiliated hospital of Zhejiang University school of medicine-Respiratory Medicine ( Site, Hangzhou, Zhejiang
Fundación Colombiana de Cancerología Clínica Vida ( Site 0603), Medellin, Antioquia
Sociedad De Oncologia Y Hematologia Del Cesar ( Site 0606), Valledupar, Cesar
Oncomedica S.A.-Oncomedica S.A ( Site 0609), Montería, Cordoba
Administradora Country S.A. - Clinica del Country ( Site 0601), Bogotá, Distrito Capital De Bogota
Oncologos del Occidente ( Site 0608), Pereira, Risaralda
CENTRE HOSPITALIER REGIONAL D'ORLEANS-Service de Pneumologie ( Site 0806), Orléans, Centre
Centre Hospitalier d'Annecy ( Site 0807), Epagny Metz-Tessy, Haute-Savoie
Institut de Cancérologie de l'Ouest ( Site 0802), ANGERS cedex 02, Maine-et-Loire
Centre Hospitalier Regional Universitaire de Lille - Hôpital-Service de pneumologie et oncologie th, Lille, Nord-Pas-de-Calais
CENTRE LEON BERARD ( Site 0803), Lyon CEDEX 08, Rhone
HIA Sainte Anne ( Site 0804), Toulon, Var
Centre Hospitalier d'Avignon ( Site 0810), Avignon, Vaucluse
UKGM Gießen/Marburg-Medical Clinic V ( Site 0912), Gießen, Hessen
GEFOS Gesellschaft f. onkologische Studien ( Site 0909), Dortmund, Nordrhein-Westfalen
Universitätsklinikum Schleswig-Holstein-Pneumologie ( Site 0902), Lübeck, Schleswig-Holstein
SRH Wald-Klinikum Gera ( Site 0911), Gera, Thuringen
Charité Campus Virchow-Klinikum-Department of Infectious Diseases and Pulmonary Medicine ( Site 0913, Berlin, Not set
Rambam Health Care Campus-Oncology ( Site 1303), Haifa, Not set
Shaare Zedek Medical Center-Oncology ( Site 1306), Jerusalem, Not set
Meir Medical Center-oncology ( Site 1301), Kfar Saba, Not set
Sheba Medical Center-ONCOLOGY ( Site 1302), Ramat Gan, Not set
Sourasky Medical Center-Oncology ( Site 1305), Tel Aviv, Not set
National Hospital Organization Shikoku Cancer Center ( Site 2414), Matsuyama, Ehime
Ehime University Hospital ( Site 2411), Toon, Ehime
Hyogo Cancer Center-Thoracic Oncology ( Site 2409), Akashi, Hyogo
Kanazawa University Hospital ( Site 2407), Kanazawa, Ishikawa
Kanagawa cancer center-Department of Thoracic Oncology ( Site 2405), Yokohama, Kanagawa
Miyagi Cancer Center ( Site 2401), Natori, Miyagi
Kansai Medical University Hospital ( Site 2415), Hirakata, Osaka
Saitama Prefectural Cancer Center ( Site 2406), Ina-machi, Saitama
Shizuoka Cancer Center ( Site 2408), Nagaizumi, Shizuoka
Japanese Foundation for Cancer Research ( Site 2402), Koto, Tokyo
Showa University Hospital ( Site 2403), Shinagawa, Tokyo
National Hospital Organization Kyushu Medical Center ( Site 2413), Fukuoka, Not set
National Hospital Organization Kyushu Cancer Center ( Site 2412), Fukuoka, Not set
Okayama University Hospital ( Site 2410), Okayama, Not set
Nippon Medical School Hospital ( Site 2404), Tokyo, Not set
Chonnam National University Hwasun Hospital-Pulmonology ( Site 2201), Hwasun, Jeonranamdo
Pusan National University Hospital ( Site 2205), Busan, Pusan-Kwangyokshi
Asan Medical Center ( Site 2206), Songpa-gu, Seoul
Kyungpook National University Chilgok Hospital-Pulmonology ( Site 2202), Deagu, Taegu-Kwangyokshi
Chungnam national university hospital-Department of Internal Medicine ( Site 2203), Daejeon, Taejon-Kwangyokshi
Korea University Guro Hospital-Internal Medicine ( Site 2204), Seoul, Not set
CENTRO DE INFUSION E INVESTIGACION ONCOLOGIA DE SALTILLO S.C. ( Site 0304), Saltillo, Coahuila
Alivia Clínica de Alta Especialidad ( Site 0310), Ciudad de Mexico, Distrito Federal
Arké SMO S.A. de C.V. ( Site 0301), Mexico, Distrito Federal
Hospital Civil Fray Antonio Alcalde ( Site 0307), Guadalajara, Jalisco
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1903), Bydgoszcz, Kujawsko-pomorskie
Centrum Medyczne Ostrobramska NZOZ Magodent ( Site 1908), Warsaw, Mazowieckie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier, Warszawa, Mazowieckie
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1904), Przemysl, Podkarpackie
Szpital Specjalistyczny w Prabutach Spolka z o.o. ( Site 1906), Prabuty, Pomorskie
Centrum Pulmonologii i Torakochirurgii w Bystrej ( Site 1907), Bystra, Slaskie
Przychodnia Lekarska KOMED ( Site 1902), Konin, Wielkopolskie
Med-Polonia Sp. z o. o. ( Site 1909), Poznan, Wielkopolskie
CHUAC-Hospital Teresa Herrera-MEDICAL ONCOLOGY ( Site 1106), A Coruña, La Coruna
Hospital Insular de Gran Canaria-Oncology ( Site 1102), Las Palmas de Gran Canaria, Las Palmas
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 1101), Barcelona, Not set
Hospital Clinico San Carlos-Oncology Department ( Site 1107), Madrid, Not set
Hospital Universitario Virgen Macarena-Unidad de Investigación Oncológica ( Site 1103), Sevilla, Not set
Hospital Clínico Universitario Lozano Blesa-Oncology ( Site 1105), Zaragoza, Not set
Kaohsiung Medical University Chung-Ho Memorial Hospital ( Site 2254), Kaohsiung, Not set
China Medical University Hospital ( Site 2253), Taichung, Not set
NATIONAL CHENG-KUNG UNI. HOSP. ( Site 2252), Tainan, Not set
National Taiwan University Hospital-Oncology ( Site 2255), Taipei, Not set
Chang Gung Medical Foundation-Linkou Branch ( Site 2251), Taoyuan, Not set
Faculty of Medicine - Khon Kaen University ( Site 2303), Muang, Khon Kaen
Faculty of Medicine Siriraj Hospital ( Site 2304), Bangkok, Krung Thep Maha Nakhon
Chulabhorn Hospital ( Site 2305), Lak Si, Krung Thep Maha Nakhon
Songklanagarind hospital ( Site 2302), Hatyai, Songkhla
Maharaj Nakorn Chiang Mai Hospital-Chiang Mai Clinical Trial Unit (CM-CTU) ( Site 2301), Chiang Mai, Not set
Acibadem Altunizade Hospital-Oncology ( Site 1207), Üsküdar / Stanbul, Istanbul
Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 1208), Adana, Not set
Hacettepe Universitesi-oncology hospital ( Site 1202), Ankara, Not set
Liv Hospital Ankara-Oncology ( Site 1205), Ankara, Not set
Ankara City Hospital ( Site 1204), Ankara, Not set
Trakya University-Medical Oncology ( Site 1203), Edirne, Not set
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1209), Istanbul, Not set
Umraniye Training and Research Hospital-medical oncology ( Site 1206), Istanbul, Not set
Leicester Royal Infirmary-HOPE Clinical Trials Unit ( Site 1502), Leicester, England
Chelsea and Westminster Hospital NHS Foundation Trust-Research and Development ( Site 1501), London, England
University College London Hospital-Cancer Clinical Trials Unit ( Site 1509), London-Camden, London, City Of
St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 1506), London, London, City Of
Conditions: Metastatic Non-Small Cell Lung Cancer
A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)
Completed
This is an international, randomized, open-label, Phase 3 study designed to evaluate whether the potent and selective RET inhibitor, pralsetinib, improves outcomes when compared to a platinum chemotherapy-based regimen chosen by the Investigator from a list of standard of care treatments, as measured primarily by progression free survival (PFS), for participants with RET fusion-positive metastatic NSCLC who have not previously received systemic anticancer therapy for metastatic disease.
This is an international, randomized, open-label, Phase 3 study designed to evaluate whether the potent and selective RET inhibitor, pralsetinib, improves outcomes when compared to a platinum chemotherapy-based regimen chosen by the Investigator from a list of standard of care treatments, as measured primarily by progression free survival (PFS), for participants with RET fusion-positive metastatic NSCLC who have not previously received systemic anticancer therapy for metastatic disease. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2025
Locations: Hospital Britanico, Buenos Aires, Not set +67 locations
Hospital Britanico, Buenos Aires, Not set
Royal North Shore Hospital, St Leonards, New South Wales
UZ Antwerpen, Edegem, Not set
Hospital Sao Lucas - PUCRS, Porto Alegre, Rio Grande Do Sul
Hospital A. C. Camargo, Sao Paulo, São Paulo
Clinica CIMCA, San Jose, Not set
Institut Bergonie CLCC Bordeaux, Bordeaux, Not set
Hôpital Ambroise Paré - Boulogne-Billancourt, Boulogne Billancourt, Not set
CHRU Lille Service de Pneumologie et Oncologie Thoracique, Lille, Not set
Institut Paoli Calmettes, Marseille, Not set
Hopital Bichat Claude Bernard, Paris, Not set
Hopital Tenon, Paris, Not set
Hopital de Pontchaillou, Rennes, Not set
CHU Strasbourg - Nouvel Hopital Civil, Strasbourg, Not set
CHU de Toulouse - Hôpital Larrey, Toulouse cedex 9, Not set
Institut Gustave Roussy, Villejuif, Not set
Universitätsklinikum Carl Gustav Carus, Medizinische Klinik I, Pneumologie MK1-A13, Dresden, Not set
Asklepios-Fachkliniken Muenchen-Gauting, Gauting, Not set
Pius-Hospital, Oldenburg, Not set
Leopoldina-Krankenhaus Medizinische Klinik II, Schweinfurt, Not set
Klinik Schillerhöhe, Stuttgart, Not set
St. James Hospital, Dublin, Not set
Ospedale Clinicizzato SS Annunziata, Chieti, Abruzzo
Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale, Napoli, Campania
Ospedale Provinciale Santa Maria Delle Croci, Ravenna, Emilia-Romagna
Istituto Nazionale Tumori Regina Elena, Roma, Lazio
AZ. Ospedaliera San Giovanni - Addolorata, Roma, Lazio
Azienda Ospedaliera Universitaria Pisana - Ospedale Cisanello, Pisa, Toscana
IOV - Istituto Oncologico Veneto - IRCCS, Padova, Veneto
A.O.U. INTEGRATA DI VERONA-Ospedale Civile Maggiore Borgo Trento, Verona, Veneto
Kyushu University Hospital, Fukuoka, Not set
National Hospital Organization Himeji Medical Center, Hyogo, Not set
Osaka International Cancer Institute, Osaka, Not set
Kansai Medical University Hospital, Osaka, Not set
Juntendo University Hospital, Tokyo, Not set
The Cancer Institute Hospital of JFCR, Tokyo, Not set
National Hospital Organization Yamaguchi - Ube Medical Center, Yamaguchi, Not set
National Cancer Center, Goyang-si, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Asan Medical Center, Seoul, Not set
Health Pharma Professional Research, Cdmx, Mexico CITY (federal District)
NKI/AvL, Amsterdam, Not set
Maastricht University Medical Center, Maastricht, Not set
Hemato Oncología de Panamá Especializada, Panama City, Not set
Narod.Inst.Onkol. im. M.Sklodowskiej - Curie-Panst.Inst.Bad, Warszawa, Not set
IPO do Porto, Porto, Not set
Insititut Catala D'Oncologia, Hospitalet de Llobregat, Barcelona
Hospital Universitario Marques de Valdecilla, Santander, Cantabria
Complejo Hospitalario Universitario A Coruña, A Coruña, LA Coruna
Hospital Universitari Vall d'Hebron, Barcelona, Not set
Hospital General Universitario Gregorio Marañon, Madrid, Not set
Hospital Ramon y Cajal, Madrid, Not set
Hospital de Madrid Norte Sanchinarro- Centro Integral Oncologico Clara Campal, Madrid, Not set
Hospital Regional Universitario de Malaga, Malaga, Not set
Hosp Clinico Univ Lozano Blesa, Zaragoza, Not set
Karolinska Universitetssjukhuset, Solna, Stockholm, Not set
UniversitätsSpital Zürich, Zürich, Not set
Adana City Hospital, Medical Oncology, Adana, Not set
Ankara Bilkent City Hospital, Ankara, Not set
?zmir Medical Point, Kar?iyaka, Not set
Velindre Cancer Centre, Cardiff, Not set
Leicester Royal Infirmary, Leicester, Not set
University College Hospital, London, Not set
Guys & St Thomas Hospital, London, Not set
Royal Marsden Hospital, London, Not set
Christie Hospital Nhs Trust, Manchester, Not set
Royal Marsden Hospital, Sutton, Not set
Conditions: RET-fusion Non Small Cell Lung Cancer, Lung Neoplasm, Carcinoma, Non-Small-Cell Lung, Respiratory Tract Neoplasms, Thoracic Neoplasms, Neoplasms by Site, Neoplasms, Lung Diseases, Respiratory Tract Disease, Carcinoma, Bronchogenic, Bronchial Diseases, Head and Neck Neoplasms, Adenocarcinoma, Carcinoma, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue
A Phase II Randomized Study Comparing the Efficacy and Safety of Targeted Therapy or Cancer Immunotherapy Versus Platinum-Based Chemotherapy in Patients With Cancer of Unknown Primary Site
Completed
This study will compare the efficacy and safety of molecularly-guided therapy versus standard platinum-containing chemotherapy in participants with poor-prognosis cancer of unknown primary site (CUP; non-specific subset) who have achieved disease control after 3 cycles of first-line platinum based induction chemotherapy.
This study will compare the efficacy and safety of molecularly-guided therapy versus standard platinum-containing chemotherapy in participants with poor-prognosis cancer of unknown primary site (CUP; non-specific subset) who have achieved disease control after 3 cycles of first-line platinum based induction chemotherapy. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2025
Locations: Blacktown Hospital, Blacktown, New South Wales +129 locations
Blacktown Hospital, Blacktown, New South Wales
GenesisCare North Shore, St Leonards, New South Wales
Icon Cancer Foundation, South Brisbane, Queensland
Flinders Medical Centre, Bedford Park, South Australia
Peter MacCallum Cancer Center, Melbourne, Victoria
Lkh-Univ. Klinikum Graz, Graz, Not set
Lkh Salzburg - Univ. Klinikum Salzburg, Salzburg, Not set
Medizinische Universität Wien, Wien, Not set
Hospital Sao Rafael - HSR, Salvador, Bahia
Hospital de Cancer de Barretos, Barretos, São Paulo
Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, São Paulo
Instituto Nacional de Cancer - INCa, Rio de Janeiro, Not set
MHAT Nadezhda, Sofia, Not set
MBAL Serdika EOOD, Sofia, Not set
Bradford Hill Centro de Investigaciones Clinicas, Recoleta, Not set
James Lind Centro de Investigación Del Cáncer, Temuco, Not set
Clinica del Country, Bogota, Not set
Inst. Nacional de Cancerologia, Bogota, Not set
Oncomedica S.A., Monteria, Not set
Clinical Hospital Centre Zagreb, Zagreb, Not set
Masarykuv onkologicky ustav, Brno, Not set
Fakultni nemocnice Olomouc, Olomouc, Not set
Fakultni Poliklinika Vseobecne Fakultni Niemocnice, Praha 2, Not set
Aarhus Universitetshospital, Aarhus N, Not set
Rigshospitalet, København Ø, Not set
North Estonia Medical Centre, Oncology and hematology Clinic, Tallinn, Not set
Helsinki University Central Hospital, Helsinki, Not set
Tampere University Hospital, Tampere, Not set
Ico - Paul Papin, Angers, Not set
CHRU Besançon, Besançon, Not set
Institut Bergonie, Bordeaux, Not set
CRLCC-Francois Baclesse, Caen, Not set
Centre Jean Perrin Centre Regional de Lutte Contre Le Cancer D auvergne, Clermont-ferrand, Not set
Centre Leon Berard, Lyon, Not set
Institut Paoli-Calmettes, Marseille Cedex 09, Not set
Institut régional du Cancer Montpellier, Montpellier, Not set
Centre Antoine Lacassagne, Nice, Not set
Institut Curie, Paris, Not set
CHU Lyon - Centre Hospitalier Lyon Sud, Pierre-Benite (Lyon), Not set
Centre Eugene Marquis, Rennes, Not set
CHU Strasbourg Hôpital Hautepierre, Strasbourg, Not set
Hopital Foch, Suresnes, Not set
Institut Gustave Roussy, Villejuif, Not set
Universitätsklinikum Augsburg, Augsburg, Not set
Charité-Universitätsm. Berlin, Berlin, Not set
Onkologisches Zentrum - Onkologie Dachau, Dachau, Not set
Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, Dresden, Not set
Kliniken Essen-Mitte, Evang. Huyssens-Stiftung, Klinik für Internistische Onkologie / Haematologie, Essen, Not set
Universitätsklinikum Frankfurt, UCT, Frankfurt, Not set
Universitätsklinikum Heidelberg, Heidelberg, Not set
SLK-Kliniken Heilbronn GmbH;Klinik für Innere Medizin III, Heilbronn, Not set
Universitätsklinikum Jena, Klinik für Innere Medizin II, Jena, Not set
Klinikum Mannheim III. Medizinische Klinik, Mannheim, Not set
Klinikum der LMU München, Campus Großhadern, Krebszentrum München, München, Not set
Universitätsklinikum Münster, Medizinische Klinik A, Translationale Onkologie, Münster, Not set
RED-Oncology GmbH, Oldenburg / Holstein, Not set
Anticancer Hospital Ag Savas, Athens, Not set
IASO General Hospital of Athens, Athens, Not set
Univ General Hosp Heraklion, Heraklion, Not set
Uni Hospital of Ioannina, Ioannina, Not set
Theagenio Anticancer Hospital, Thessaloniki, Not set
Orszagos Onkologiai Intezet, Budapest, Not set
Budapesti Uzsoki Utcai Kórház, Budapest, Not set
Bács-Kiskun Vármegyei Oktatókórház, Kecskemét, Not set
St Vincent'S Uni Hospital, Dublin, Not set
Waterford Regional Hospital, Waterford, Not set
Rabin MC, Petach Tikva, Not set
Chaim Sheba medical center, Oncology division, Ramat Gan, Not set
Tel Aviv Sourasky Medical Ctr, Tel Aviv, Not set
U. O. Oncologia Medica, Ospedale Santa Chiara, Pisa, Basilicata
Policlinico Univ. - A.O. Mater Domini, Catanzaro, Calabria
Istituto Nazionale Tumori Fondazione G. Pascale, Napoli, Campania
Arcispedale Santa Maria Nuova, Reggio Emilia, Emilia-Romagna
Asst Papa Giovanni XXIII, Bergamo, Lombardia
Azienda Socio Sanitaria Territoriale Niguarda (Ospedale Niguarda Ca' Granda), Milano, Lombardia
IRCCS Istituto Oncologico Veneto (IOV), Padova, Veneto
National Cancer Center Hospital East, Chiba, Not set
National Hospital Organization Kyushu Cancer Center, Fukuoka, Not set
Seoul National University Hospital, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Riga East Clinical University Hospital Latvian Oncology Centre, Riga, Not set
Health Pharma Professional Research, CD Mexico, Mexico CITY (federal District)
AVIX Investigación Clínica S.C, Monterrey, Nuevo LEON
Erasmus MC, Rotterdam, Not set
Universitair Medisch Centrum Utrecht, Utrecht, Not set
Ziekenhuis VieCuri Medisch Centrum, Venlo, Not set
Sørlandet Sykehus Kristiansand, Kristiansand, Not set
Akershus universitetssykehus HF, Lørenskog, Not set
Oslo universitetssykehus HF, Ullevål, Kreftsenteret, Oslo, Not set
Instituto Nacional de Enfermedades Neoplasicas, Lima, Not set
Oncosalud Sac, Lima, Not set
Szpital Uniwersytecki w Krakowie, Oddzia? Kliniczny Kliniki Onkologii, Kraków, Not set
IPO do Porto, Porto, Not set
Institutul Oncologic Prof. Dr. Ion Chiricuta Cluj Napoca, Cluj Napoca, Not set
Centrul de Oncologie Sfantul Nectarie, Craiova, Not set
Institutul Regional de Oncologie Iasi, Iasi, Not set
Oncocenter Timisoara, Timi?oara, Not set
Hospital Sant Joan Despi- Moises Broggi, Sant Joan Despí, Barcelona
Complejo Hospitalario de Navarra, Pamplona, Navarra
Complexo Hospitalario de Vigo. Hospital Álvaro Cunqueiro, Vigo, Pontevedra
Hospital Clínic i Provincial, Barcelona, Not set
Institut Catala d Oncologia Hospital Duran i Reynals, Barcelona, Not set
Hospital Ramon y Cajal, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital Clinico Universitario Virgen de la Victoria, Malaga, Not set
Hospital Universitario Virgen Macarena, Sevilla, Not set
Hospital Universitari i Politecnic La Fe, Valencia, Not set
Hospital Universitario Miguel Servet, Zaragoza, Not set
Universitaetsspital Basel, Basel, Not set
UniversitätsSpital Zürich, Zürich, Not set
Ramathibodi Hospital;Medicine/Oncology, Bangkok, Not set
Faculty of Med. Siriraj Hosp., Bangkok, Not set
Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital, Adana, Not set
Ankara University Medical Faculty, Ankara, Not set
Ankara Oncology Hospital, Ankara, Not set
Akdeniz University Medical Faculty, Antalya, Not set
Trakya Universitesi Tip Fakultesi, Medikal Onkoloji Bilim Dali, Balkan Yerleskesi, Edirne, Not set
Istanbul University Cerrahpa?a-Cerrahpa?a Medical Faculty, Istanbul, Not set
?zmir Medical Point, Kar?iyaka, Not set
Hacettepe Uni Medical Faculty Hospital, S?hhiye, Ankara, Not set
Royal United Hospital, Bath, Not set
Velindre Cancer Centre, Cardiff, Not set
Western General Hospital, Edinburgh, Not set
Hammersmith Hospital, London, Not set
Christie Hospital NHS Trust, Manchester, Not set
Freeman Hospital, Newcastle upon Tyne, Not set
Southampton General Hospital, Southampton, Not set
Torbay Hospital, Torquay, Not set
Conditions: Cancer of Unknown Primary Site
Avelumab in First-line NSCLC (JAVELIN Lung 100)
Completed
The purpose of this study was to demonstrate superiority with regard to Overall Survival (OS) or Progression Free Survival (PFS) of avelumab versus platinum-based doublet, based on an Independent Review Committee assessment, in Non-small cell lung cancer (NSCLC) participants with Programmed death ligand 1+ (PD-L1+) tumors.
The purpose of this study was to demonstrate superiority with regard to Overall Survival (OS) or Progression Free Survival (PFS) of avelumab versus platinum-based doublet, based on an Independent Review Committee assessment, in Non-small cell lung cancer (NSCLC) participants with Programmed death ligand 1+ (PD-L1+) tumors. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/20/2025
Locations: Clearview Cancer Institute, Huntsville, Alabama +348 locations
Clearview Cancer Institute, Huntsville, Alabama
Arizona Center for Cancer Care, Surprise, Arizona
Sharp Memorial Hospital, San Diego, California
University Cancer Institute, Boynton Beach, Florida
South Georgia Medical Center, Valdosta, Georgia
Christus Cancer Treatment Center, Shreveport, Louisiana
Henry Ford Hospital, Detroit, Michigan
St. Vincent Frontier Cancer Center, Billings, Montana
Nevada Cancer Research Foundation, Las Vegas, Nevada
San Juan Oncology Associates, Farmington, New Mexico
Novant Health Oncology Specialists, Kernersville, North Carolina
Mercy Research, Oklahoma City, Oklahoma
Kaiser Permanente Northwest, Portland, Oregon
Lancaster Cancer Center, Lancaster, Pennsylvania
Cookeville Regional Medical Center, Cookeville, Tennessee
Thompson Cancer Survival Center, Knoxville, Tennessee
Coastal Bend Cancer Center, Corpus Christi, Texas
Oncology Consultants, P.A., Houston, Texas
University of Vermont Medical Center, Burlington, Vermont
Northwest Medical Specialties, PLLC, Tacoma, Washington
Cheyenne Regional Medical Center, Cheyenne, Wyoming
Albury Wodonga Regional Cancer Centre, Albury, New South Wales
Coffs Harbour Health Campus, Coffs Harbour, New South Wales
St George Private Hospital, Kogarah, New South Wales
Lismore Base Hospital, Lismore, New South Wales
Orange Health Service, Orange, New South Wales
Royal North Shore Hospital, St Leonards, New South Wales
Calvary Mater Newcastle, Waratah, New South Wales
Gallipoli Medical Research Foundation Ltd, Greenslopes, Queensland
Gold Coast University Hospital, Southport, Queensland
The Queen Elizabeth Hospital, Woodville South, South Australia
Ballarat Base Hospital, Ballarat, Victoria
Bendigo Hospital, Bendigo, Victoria
South West Healthcare, Warrnambool, Victoria
Fiona Stanley Hospital, Murdoch, Western Australia
ZNA Middelheim, Antwerpen, Not set
A.Z. Klina, Brasschaat, Not set
CHU Ambroise Paré, Mons, Not set
NOB - Núcleo de Oncologia da Bahia, Salvador, Bahia
CRIO - Centro Regional Integrado de Oncologia, Fortaleza, Ceará
CEBROM - Centro Brasileiro de Radioterapia, Oncologia e Mastologia, Goiânia, Goiás
Hospital Erasto Gaertner - Liga Paranaense de Combate ao Câncer, Curitiba, Paraná
Hospital de Caridade de Ijuí, Ijuí, Rio Grande Do Sul
Hospital Bruno Born, Lajeado, Rio Grande Do Sul
Hospital São Vicente de Paulo, Passo Fundo, Rio Grande Do Sul
Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul
IMV-Pesquisa Cardiologica Sociedade Simples - HMD - COR, Porto Alegre, Rio Grande Do Sul
Hospital São Lucas da PUCRS, Porto Alegre, Rio Grande Do Sul
Hospital Nossa Senhora da Conceição, Porto Alegre, Rio Grande Do Sul
CEPON - Centro de Pesquisas Oncológicas de Santa Catarina, Florianópolis, Santa Catarina
Clínica de Neoplasias Litoral Ltda., Itajaí, Santa Catarina
Hospital de Câncer de Barretos - Fundação Pio XII, Barretos, Sao Paulo
Fundação Doutor Amaral Carvalho, Jaú, Sao Paulo
CEPHO - Centro de Estudos e Pesquisas em Hematologia e Oncologia, Santo Andre, Sao Paulo
Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto, Sao Paulo
ICESP - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira, São Paulo, Sao Paulo
IBCC - Instituto Brasileiro de Controle do Câncer, São Paulo, Sao Paulo
INCA - Instituto Nacional de Câncer, Rio de Janeiro, Not set
Complex Oncological Center - Ruse, EODD, Ruse, Not set
MHAT for women's health - Nadezhda, OOD, Sofia, Not set
UMHAT "Sv. Ivan Rilski", EAD, Sofia, Not set
Shato, Ead, Sofia, Not set
The Moncton Hospital, Moncton, New Brunswick
Mount Sinai Hospital, Toronto, Ontario
FALP - Fundación Arturo López Pérez, Santiago, Not set
Clinica Santa Maria, Santiago, Not set
IRAM - Instituto de Radio Medicina, Santiago, Not set
Hospital Militar de Santiago, Santiago, Not set
Hospital Clínico San Borja Arriaran, Santiago, Not set
Hospital Clínico Universidad de Chile, Santiago, Not set
Hospital Clinico Viña del Mar, Viña del Mar, Not set
Centro de Investigaciones Clinicas Viña del Mar, Viña del Mar, Not set
Beijing Cancer Hospital, Beijing, Beijing
Guangdong General Hospital, Guangzhou, Guangdong
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang
Liaoning Cancer Hospital & Institute, Shenyang, Liaoning
Linyi Cancer Hospital, Linyi, Shandong
Administradora Country S.A., Bogotá, Not set
Fundación Oftalmológica de Santander - FOSCAL, Floridablanca, Not set
Hospital Pablo Tobón Uribe, Medellín, Not set
IPS IMAT- Instituto Medico de Alta Tecnologia - Oncomedica S.A., Monteria, Not set
University Clinic for Pulmonary Diseases, Zagreb, Not set
University Hospital Centre "Sestre Milosrdnice", Zagreb, Not set
Bank of Cyprus Oncology Center, Nicosia, Not set
Krajska nemocnice Liberec, a.s., Liberec, Not set
Nemocnice Na Plesi s.r.o., Nova Ves pod Plesi, Not set
Fakultni nemocnice Olomouc, Olomouc, Not set
Vitkovicka nemocnice a.s, Ostrava - Vitkovice, Not set
Thomayerova nemocnice, Praha 4 - Krc, Not set
Krajska zdravotni, a.s. - Masarykova nemocnice v Usti nad Labem, o.z., Usti nad Labem, Not set
Herning Sygehus, Herning, Not set
Roskilde Sygehus, Roskilde, Not set
North Estonia Medical Centre Foundation, Tallinn, Not set
Centre Antoine Lacassagne, Nice cedex 02, Alpes Maritimes
CHU de Strasbourg - Nouvel Hôpital Civil, Strasbourg, Bas Rhin
Hôpital Nord - AP-HM Marseille#, Marseille cedex 20, Bouches-du-Rhône
Hôpital privé Clairval, Marseille, Bouches-du-Rhône
CHU Besançon - Hôpital Jean Minjoz, Besancon Cedex, Doubs
CHU Brest - Hôpital Morvan, Brest Cedex, Finistere
Groupe Hospitalier Sud - Hôpital Haut-Lévêque, Pessac, Gironde
CHU Angers - Hôpital Hôtel Dieu#, Angers Cedex 9, Maine Et Loire
Hôpital Cochin, Paris cedex 14, Paris
Centre Hospitalier de la Côte Basque, Bayonne, Pyrenees Atlantiques
Centre Hospitalier de la Croix Rousse, Lyon cedex 04, Rhone
Clinique Victor Hugo - Centre Jean Bernard, Le Mans Cedex 02, Sarthe
Institut Sainte Catherine, Avignon Cedex 9, Vaculuse
Centre Hospitalier Intercommunal de Créteil, Creteil cedex, Val De Marne
Hôpital Saint-Louis - Paris, Paris Cedex 10, Not set
Universitaetsklinikum Heidelberg, Heidelberg, Baden Wuerttemberg
LungenClinic Grosshansdorf GmbH, Grosshansdorf, Schleswig Holstein
251 General Air Force Hospital, Athens, Not set
General Hospital of Athens of Chest Diseases "SOTIRIA", Athens, Not set
University General Hospital "Attikon", Athens, Not set
General Oncology Hospital of Kifissia " Agioi Anargyroi", Athens, Not set
Metropolitan General Hospital, Athens, Not set
University General Hospital of Heraklion, Heraklion, Not set
University General Hospital of Patra, Patras, Not set
Euromedica General Clinic Thessaloniki, Thessaloniki, Not set
Orszagos Koranyi Pulmonologiai Intezet, Budapest, Not set
Orszagos Onkologiai Intezet, Budapest, Not set
Semmelweis Egyetem, Budapest, Not set
Orszagos Koranyi Pulmonologiai Intezet, Budapest, Not set
Csongrad Megyei Mellkasi Betegsegek Szakkorhaza, Deszk, Not set
Petz Aladar Megyei Oktato Korhaz, Györ, Not set
Borsod-Abauj-Zemplen Megyei Kozponti Korhaz es Egyetemi Oktatokorhaz, Miskolc, Not set
SzSzB Megyei Korhazak es Egyetemi Oktatokorhaz, Nyiregyhaza, Not set
Tolna Megyei Balassa Janos Korhaz, Szekszard, Not set
Tudogyogyintezet Torokbalint, Torokbalint, Not set
Zala Megyei Szent Rafael Korhaz, Zalaegerszeg, Not set
Cork University Hospital, Cork, Not set
Soroka University Medical Center, Beer Sheva, Not set
Rambam Health Care Center, Haifa, Not set
Hadassah University Hospital - Ein Kerem, Jerusalem, Not set
Sapir Medical Center, Meir Hospital, Kfar-Saba, Not set
Rabin Medical Center-Beilinson Campus, Petach Tikva, Not set
Chaim Sheba Medical Center, Ramat Gan, Not set
Kaplan Medical Center, Rechovot, Not set
Assaf Harofeh, Rishon Lezion, Not set
Tel Aviv Sourasky Medical Center, Tel Aviv, Not set
Ospedale Mater Salutis, Legnago, Verona
Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Not set
Presidio Ospedaliero Garibaldi Nesima, Catania, Not set
Azienda Ospedaliero Universitaria San Martino, Genova, Not set
Seconda Università degli Studi di Napoli, Napoli, Not set
Azienda Ospedaliero Universitaria di Parma, Parma, Not set
Azienda Ospedaliero Universitaria Pisana, Pisa, Not set
National Cancer Center Hospital East, Kashiwa-shi, Chiba-Ken
Kurume University Hospital, Kurume-shi, Fukuoka-Ken
NHO Hokkaido Cancer Center, Sapporo-shi, Hokkaido
Institute of Biomedical Research and Innovation Hospital, Kobe-shi, Hyogo-Ken
Kobe City Hospital Organization Kobe City Medical Center General Hospital, Kobe-shi, Hyogo-Ken
Yokohama Municipal Citizen's Hospital, Yokohama-shi, Kanagawa-Ken
Kanagawa Cancer Center, Yokohama-shi, Kanagawa-Ken
Kansai Medical University Hospital, Hirakata-shi, Osaka-Fu
Osaka Medical College Hospital, Takatsuki-shi, Osaka-Fu
National Cancer Center Hospital, Chuo-ku, Tokyo-To
Tokyo Medical University Hospital, Shinjuku-ku, Tokyo-To
Toyama University Hospital, Toyama-shi, Toyama-Ken
Kobe City Hospital Organization Kobe City Medical Center General Hospital, Kobe-shi, Not set
Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do
Yonsei University Wonju Severance Christian Hospital, Wonju-si, Gangwon-do
Inje University Haeundae Paik Hospital, Busan, Gyeonggi-do
National Cancer Center, Goyang-si, Gyeonggi-do
CHA Bundang Medical Center, CHA University, Seongnam-si, Gyeonggi-do
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do
The Catholic University of Korea, St. Vincent's Hospital, Suwon-si, Gyeonggi-do
Ajou University Hospital, Suwon-si, Gyeonggi-do
Kyungpook National University Chilgok Hospital, Daegu, Not set
Gachon University Gil Medical Center, Incheon, Not set
Korea University Anam Hospital, Seoul, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital, Yonsei University, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Not set
The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
Ulsan University Hospital, Ulsan, Not set
American University of Beirut Medical Center, Beirut, Not set
Rafik Hariri University Hospital, Beirut, Not set
Hotel Dieu de France Hospital, Beirut, Not set
Mount Lebanon Hospital, Beirut, Not set
Hammoud Hospital University Medical Center, Saida, Not set
Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, Not set
Martini Ziekenhuis, Groningen, Not set
Westfriesgasthuis - PARENT, Hoorn, Not set
ETZ Elisabeth, Tilburg, Not set
Auckland City Hospital, Auckland, Not set
Dunedin Public Hospital, Dunedin, Not set
Waikato Hospital, Hamilton, Not set
Palmerston North Hospital, Palmerston North, Not set
Tauranga Hospital, Tauranga, Not set
Wellington Hospital, Wellington, Not set
Instituto Nacional de Enfermedades Neoplásicas, Lima, Not set
Clinica Internacional Sede San Borja, Lima, Not set
Oncosalud, Lima, Not set
Centrum Terapii Wspolczesnej J.M. Jasnorzewska sp. komandytowo-akcyjna, Lodz, Not set
Instytut MSF Sp. o.o, Lodz, Not set
Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Łodzi, Lodz, Not set
KO-MED Centra Kliniczne Lublin II, Lublin, Not set
SSZZOZ im. Dr Teodora Dunina w Rudce, Mrozy, Not set
SP Zespol Gruzlicy i Chorob Pluc w Olsztynie, Olsztyn, Not set
Mazowieckie Centrum Leczenia Chorob Pluc i Gruzlicy, Otwock, Not set
Szpital Kliniczny Przemienienia Panskiego Uniwersytetu Medycznego im. Karola Marcinkowskiego, Poznan, Not set
Izerskie Centrum Pulmonologii i Chemioterapii "IZER-MED" Spolka z o.o., Szklarska Poręba, Not set
Centrum Onkologii-Instytut im. M. Sklodowskiej Curie, Warszawa, Not set
Mazowiecki Szpital Onkologiczny, Wieliszew, Not set
Hospital Garcia de Orta, EPE, Almada, Not set
Hospital Professor Doutor Fernando Fonseca, E.P.E., Amadora-Lisbon, Not set
Centro Hospitalar De Coimbra-CHUC, Coimbra, Not set
Centro Hospitalar e Universitário de Coimbra, E.P.E (CHC), Coimbra, Not set
Centro Hospitalar de Lisboa Norte, E.P.E. - Hospital Pulido Valente, Lisboa, Not set
Centro Hospitalar de Lisboa Central, E.P.E. - Hospital de Santo António dos Capuchos, Lisboa, Not set
Centro Hospitalar do Porto, E.P.E. - Hospital de Santo António, Porto, Not set
Hospital CUF Porto, Porto, Not set
Instituto Português de Oncologia do Porto Francisco Gentil, EPE, Porto, Not set
Centro Hospitalar de São João, E.P.E., Porto, Not set
Centro Hospitalar de Entre o Douro e Vouga, E.P.E - Hospital de São Sebastião, Santa Maria da Feira, Not set
Centro Hospitalar Vila Nova de Gaia/Espinho, E.P.E, Vila Nova de Gaia, Not set
Spitalul Judetean de Urgenta "Dr. Constantin Opris" Baia Mare, Baia Mare, Not set
S.C Policlinica de Diagnostic Rapid S.A, Brasov, Not set
Institutul Oncologic "Prof. Dr. Al. Trestioreanu", Bucuresti, Not set
Spitalul Clinic Coltea, Bucuresti, Not set
S.C Gral Medical S.R.L, Bucuresti, Not set
Institutul Oncologic "Prof. Dr. Ion Chiricuta" Cluj Napoca, Cluj Napoca, Not set
S.C Medisprof S.R.L, Cluj-Napoca, Not set
Spitalul Militar de Urgenta "Dr.Constantin Papilian"Cluj -Napoca, Cluj-Napoca, Not set
S.C Radiotherapy Center Cluj S.R.L, Comuna Floresti, Not set
Spitalul Clinic Judetean de Urgenta "Sf. Apostol Andrei" Constanta, Constanta, Not set
S.C Centrul de Oncologie Sf. Nectarie S.R.L, Craiova, Not set
Institutul Regional de Oncologie Iasi, Iasi, Not set
S.C Pelican Impex S.R.L, Oradea, Not set
Spitalul Clinic Municipal "Dr. Gavril Curteanu" Oradea, Oradea, Not set
Spitalul Judetean de Urgenta "Sf. Ioan cel Nou" Suceava, Suceava, Not set
S.C Oncocenter Oncologie Clinica S.R.L, Timisoara, Not set
S.C Oncomed S.R.L, Timisoara, Not set
SBIH of Arkhangelsk region "Arkhangelsk Clinical Oncological Dispensary", Arkhangelsk, Not set
LLC Evimed, Chelyabinsk, Not set
Chelyabinsk Regional Oncology Dispensary, Chelyabinsk, Not set
Irkutsk Regional Oncology Dispensary, Irkutsk, Not set
RBIH "Ivanovo Regional Oncological Dispensary", Ivanovo, Not set
SBHI of Kaluga Region "Kaluga regional clinical oncology dispensary", Kaluga, Not set
SAIH "Republican Clinical Oncological Dispensary of the Ministry of Healthcare of Republic Tatarstan, Kazan, Not set
Kemerovo SPI Regional Clinical Oncology Dispensary, Kemerovo, Not set
SBHI "Krasnoyarsk Regional Oncology Dispensary n.a. A.I. Kryzhanovsky", Krasnoyarsk, Not set
RBIH "Kursk regional clinical oncology dispensary" of Kursk Region Healthcare Committee, Kursk, Not set
FSBSI "Russian Oncological Scientific Center n.a. N.N. Blokhin", Moscow, Not set
Murmansk Regional Clinical Hospital named after Bayandin, Murmansk, Not set
SBHI of Novosibirsk region "Novosibirsk Regional Oncological Dispensary", Novosibirsk, Not set
SBIH of Stavropol territory "Pyatigorsk Oncological Dispensary", Pyatigorsk, Not set
SBIH "Leningrad Regional Oncological Dispensary", Saint-Petersburg, Not set
"Bio Eq" LLC, Saint-Petersburg, Not set
FBI "Scientific Research Institute of Oncology n. a. N. N. Petrov", Saint-Petersburg, Not set
SBIH "Samara Regional Clinical Oncological Dispensary", Samara, Not set
SBIH "Oncological Dispensary # 2" of the MoH of Krasnodar territory, Sochi, Not set
FSBHI Clinical research institute of phthisiopulmonology, St. Petersburg, Not set
Tomsk Research Instutite of Oncology, Tomsk, Not set
BHI of Omsk region "Clinical Oncology Dispensary", Tomsk, Not set
Medicinskiy gorod, Tyumen, Not set
SBIH of Yaroslavl region "Regional Clinical Oncological Hospital", Yaroslavl, Not set
Clinical Center of Serbia, Belgrade, Not set
Institute of Oncology and Radiology of Serbia, Belgrade, Not set
Military Medical Academy, Belgrade, Not set
Clinical Center Bezanijska Kosa, Belgrade, Not set
Clinical Center Nis, Pulmonary Diseases Clinic, Gornji Matejevac, Not set
Clinical Center Kragujevac, Kragujevac, Not set
Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Not set
National University Cancer Institute, Singapore, Not set
National Cancer Centre, Singapore, Not set
Tan Tock Seng Hospital, Singapore, Not set
Nemocnica s poliklinikou Sv. Jakuba, n.o. Bardejov, Bardejov, Not set
Univerzitna nemocnica Bratislava, Nemocnica Ruzinov, Bratislava, Not set
Emery Clinical Services, Alberton, Gauteng
University of Pretoria Oncology Department, Pretoria, Gauteng
Johese Clinical Research, Pretoria, Gauteng
Cape Town Oncology Trials Pty Ltd, Cape Town, Western Cape
Hospital de Mataro, Mataro, Barcelona
Hospital Universitario Mutua de Terrassa, Terrassa, Barcelona
Hospital Universitario Donostia, San Sebastian, Guipuzcoa
Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, La Coruña
Complejo Hospitalario Universitario de Vigo, Vigo, Pontevedra
Specialist, Barcelona, Not set
Hospital Universitari Quiron Dexeus, Barcelona, Not set
Hospital Universitari Vall d'Hebron, Barcelona, Not set
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
ICO Girona - Hospital Universitari de Girona Dr. Josep Trueta, Girona, Not set
Hospital General Universitario Gregorio Marañon, Madrid, Not set
MD Anderson Cancer Centre, Madrid, Not set
Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Hospital Regional Universitario de Malaga, Málaga, Not set
Hospital Quiron Sagrado Corazon, Sevilla, Not set
Hospital Universitario Virgen del Rocio, Sevilla, Not set
Hospital Txagorritxu, Vitoria, Not set
Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Not set
China Medical University Hospital, Taichung, Not set
Taichung Veterans General Hospital, Taichung, Not set
National Taiwan University Hospital, Taipei, Not set
Taipei Veterans General Hospital, Taipei, Not set
Tri-Service General Hospital, Taipei, Not set
Chang Gung Memorial Hospital, Linkou, Taoyuan County, Not set
King Chulalongkorn Memorial Hospital, Patumwan, Bangkok
Rajavithi Hospital, Rajathevee, Bangkok
Maharaj Nakorn Chiang Mai Hospital, Muang, Chiang Mai
Srinagarind Hospital, Muang, Khon Kaen
Naresuan University Hospital, Muang, Phitsanulok
Songklanagarind Hospital, Hat Yai, Songkhla
Siriraj Hospital, Bangkok, Not set
Acibadem Adana Hospital, Adana, Not set
Baskent University Adana Application and Research Center, Adana, Not set
Adana Numune Training and Research Hospital, Adana, Not set
Cukurova University Medical Faculty, Adana, Not set
Adana City Hospital, Adana, Not set
Ankara University Medical Faculty, Ankara, Not set
Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Not set
Hacettepe University Medical Faculty, Ankara, Not set
Memorial Antalya Hastanesi, Antalya, Not set
Okmeydani Research and Training Hospital, Istanbul, Not set
Istanbul University Cerrahpasa Medical Faculty, Istanbul, Not set
Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital, Istanbul, Not set
Medipol University Medical Faculty, Istanbul, Not set
Kartal Lutfi Kirdar Research and Training Hospital, Istanbul, Not set
Ege University Medical Faculty, Izmir, Not set
Inonu Uni. Med. Fac., Malatya, Not set
Mersin University Medical Faculty, Mersin, Not set
Sakarya Traning and Research Hospital, Sakarya, Not set
Namik Kemal University, Tekirdag, Not set
CI Chernivtsi RC Oncological Dispensary Bukovinian SMU Ch of Oncology and Radiology, Chernivtsi, Not set
CI Dnipropetrovsk CMCH #4 of Dnipropetrovsk RC Dept of Chemotherapy SI Dnipropetrovsk MA of MOHU, Dnipro, Not set
CI Transcarpathian Cl Onc Center Dep of Surgery#1 SHEI Ivano-Frankivsk NMU, Ivano-Frankivsk, Not set
SI S.P.Grygoriev Institute of Medical Radiology of NAMSU, Kharkiv, Not set
Communal Non-profit Enterprise Regional Center of Oncology, Kharkiv, Not set
Kherson Regional Oncologic Dispensary, Kherson, Not set
Treatment-Diagnostic Center of Private Enterprise of PPC Atsynus, Kropyvnytskyi, Not set
CI Kryvyi Rih Oncological Dispensary of DRC, Kryvyi Rih, Dnipropetrovsk Region, Not set
Kyiv City Clinical Oncological Center, Kyiv, Not set
Treatment-Prevention Institution Volyn Regional Oncological Dispensary, Lutsk, Not set
Lviv State Oncological Regional Treatment and Diagnostic Center, Lviv, Not set
Odesa Regional Oncologic Dispensary, Odesa, Not set
RCI Sumy Regional Clinical Oncological Dispensary, Sumy, Not set
CCCH City Oncological Center SHEI Uzhgorod NU, Uzhgorod, Not set
Podilskyi Regional Oncological Center, Vinnytsia, Not set
Vinnytsia Regional Clinical Oncological Dispensary, Vinnytsia, Not set
Southend University Hospital, Westcliff on Sea, Essex
Cheltenham General Hospital, Cheltenham, Gloucestershire
Chelsea and Westminster Hospital, London, Greater London
Mount Vernon Hospital, Stevenage, Hertfordshire
The Clatterbridge Cancer Centre, Wirral, Merseyside
Royal Stoke University Hospital, Stoke on Trent, Staffordshire
Conditions: First Line Non-Small Cell Lung Cancer
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients with Relapsed or Refractory Germ Cell Tumors
Active Not Recruiting
This randomized phase III trial studies how well standard-dose combination chemotherapy works compared to high-dose combination chemotherapy and stem cell transplant in treating patients with germ cell tumors that have returned after a period of improvement or did not respond to treatment. Drugs used in chemotherapy, such as paclitaxel, ifosfamide, cisplatin, carboplatin, and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from d... Read More
This randomized phase III trial studies how well standard-dose combination chemotherapy works compared to high-dose combination chemotherapy and stem cell transplant in treating patients with germ cell tumors that have returned after a period of improvement or did not respond to treatment. Drugs used in chemotherapy, such as paclitaxel, ifosfamide, cisplatin, carboplatin, and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving chemotherapy before a stem cell transplant stops the growth of cancer cells by stopping them from dividing or killing them. Giving colony-stimulating factors, such as filgrastim or pegfilgrastim, and certain chemotherapy drugs, helps stem cells move from the bone marrow to the blood so they can be collected and stored. Chemotherapy is then given to prepare the bone marrow for the stem cell transplant. The stem cells are then returned to the patient to replace the blood-forming cells that were destroyed by the chemotherapy. It is not yet known whether high-dose combination chemotherapy and stem cell transplant are more effective than standard-dose combination chemotherapy in treating patients with refractory or relapsed germ cell tumors. Read Less
Gender:
MALE
Ages:
14 years and above
Trial Updated:
01/09/2025
Locations: Children's Hospital of Alabama, Birmingham, Alabama +124 locations
Children's Hospital of Alabama, Birmingham, Alabama
UC San Diego Moores Cancer Center, La Jolla, California
Loma Linda University Medical Center, Loma Linda, California
USC / Norris Comprehensive Cancer Center, Los Angeles, California
Kaiser Permanente-Oakland, Oakland, California
Stanford Cancer Institute Palo Alto, Palo Alto, California
UCSF Medical Center-Mission Bay, San Francisco, California
Alfred I duPont Hospital for Children, Wilmington, Delaware
MedStar Georgetown University Hospital, Washington, District of Columbia
University of Florida Health Science Center - Gainesville, Gainesville, Florida
Nemours Children's Clinic-Jacksonville, Jacksonville, Florida
Nicklaus Children's Hospital, Miami, Florida
Miami Cancer Institute, Miami, Florida
Arnold Palmer Hospital for Children, Orlando, Florida
Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida
Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia
Northwestern University, Chicago, Illinois
Rush University Medical Center, Chicago, Illinois
University of Illinois, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Ascension Via Christi Hospitals Wichita, Wichita, Kansas
Cancer Center of Kansas - Wichita, Wichita, Kansas
Ochsner Medical Center Jefferson, New Orleans, Louisiana
Dana-Farber Cancer Institute, Boston, Massachusetts
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan
Spectrum Health at Butterworth Campus, Grand Rapids, Michigan
University of Michigan Health - West, Wyoming, Michigan
Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota
Mayo Clinic in Rochester, Rochester, Minnesota
Washington University School of Medicine, Saint Louis, Missouri
Nebraska Methodist Hospital, Omaha, Nebraska
Summerlin Hospital Medical Center, Las Vegas, Nevada
Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey
Hackensack University Medical Center, Hackensack, New Jersey
Memorial Sloan Kettering Monmouth, Middletown, New Jersey
Saint Joseph's Regional Medical Center, Paterson, New Jersey
Roswell Park Cancer Institute, Buffalo, New York
Memorial Sloan Kettering Commack, Commack, New York
Memorial Sloan Kettering Cancer Center, New York, New York
Memorial Sloan Kettering Nassau, Uniondale, New York
Memorial Sloan Kettering Westchester, West Harrison, New York
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Ohio State University Comprehensive Cancer Center, Columbus, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania
University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania
Rhode Island Hospital, Providence, Rhode Island
Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina
Medical University of South Carolina, Charleston, South Carolina
Prisma Health Cancer Institute - Easley, Easley, South Carolina
Saint Francis Hospital, Greenville, South Carolina
BI-LO Charities Children's Cancer Center, Greenville, South Carolina
Prisma Health Cancer Institute - Butternut, Greenville, South Carolina
Prisma Health Cancer Institute - Faris, Greenville, South Carolina
Prisma Health Greenville Memorial Hospital, Greenville, South Carolina
Saint Francis Cancer Center, Greenville, South Carolina
Prisma Health Cancer Institute - Eastside, Greenville, South Carolina
Prisma Health Cancer Institute - Greer, Greer, South Carolina
Prisma Health Cancer Institute - Seneca, Seneca, South Carolina
Spartanburg Medical Center, Spartanburg, South Carolina
Saint Jude Children's Research Hospital, Memphis, Tennessee
The Children's Hospital at TriStar Centennial, Nashville, Tennessee
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee
El Paso Children's Hospital, El Paso, Texas
M D Anderson Cancer Center, Houston, Texas
Seattle Children's Hospital, Seattle, Washington
Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin
Marshfield Medical Center-Marshfield, Marshfield, Wisconsin
Medical College of Wisconsin, Milwaukee, Wisconsin
Marshfield Clinic-Minocqua Center, Minocqua, Wisconsin
Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin
Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin
Marshfield Medical Center - Weston, Weston, Wisconsin
Royal Prince Alfred Hospital, Camperdown, New South Wales
Princess Alexandra Hospital, Woolloongabba, Queensland
Box Hill Hospital, Box Hill, Victoria
Peter MacCallum Cancer Centre, Melbourne, Victoria
Institut Jules Bordet, Anderlecht, Not set
University Hospital Saint Luc, Brussels, Not set
Rigshospitalet University Hospital, Copenhagen, Not set
Centre Leon Berard, Lyon, Not set
Institut Paoli Calmettes, Marseille, Not set
Hopital Tenon/Assistance Publique - Hopitaux de Paris, Paris, Not set
CHRU Strasbourg - Hospital Civil, Strasbourg, Not set
Center Claudius Regaud, Toulouse, Not set
Centre Alexis Vautrin, Vandoeuvre-les-Nancy, Not set
Gustave Roussy, Villejuif, Not set
Technical University Dresden, Dresden, Saxony
University of Berlin Charite Campus Benjamin Franklin, Berlin, Not set
University of Dusseldorf, Dusseldorf, Not set
University of Essen, Essen, Not set
University Medical Center Hamburg-Eppendorf, Hamburg, Not set
UniversitaetsKlinikum Heidelberg, Heidelberg, Not set
GK-Mittelrhein Saint Martin's, Koblenz, Not set
Philipps University Marburg, Marburg, Not set
Rotkreuzklinikum Munchen, Munich, Not set
Klinikum Nurnberg Nord, Nurnberg, Not set
University Hospital Ulm, Ulm, Not set
Saint James Hospital, Dublin, Not set
Ospedale di Circolo di Busto Arsizio, Busto Arsizio, Not set
Istituto Scientifico Romagnolo, Meldola, Not set
Istituto Nazionale Tumori, Milano, Not set
San Matteo Hospital, Pavia, Not set
The Netherlands Cancer Institute, Amsterdam, Not set
University Medical Center Groningen, Groningen, Not set
Radboud University Nijmegen Medical Centre, Nijmegen, Not set
Hospital De La Santa Creu I Sant Pau, Barcelona, Not set
Duran i Reynals Hospital-Catalan Institute of Oncology, Barcelona, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital General Universitario Morales Meseguer, Murcia, Not set
Inselspital, Bern, Not set
Hopitaux Universitaires de Geneve, Geneva, Not set
University Hospital Zurich, Zurich, Not set
Saint Bartholomew's Hospital, London, England
Christie Hospital, Manchester, England
Weston Park Hospital, Sheffield, England
Southampton General Hospital, Southampton, England
Saint James's University Hospital, West Yorkshire, England
Beatson Oncology Center, Glasgow, Scotland
Nottingham City Hospital, Nottingham, Not set
The Royal Marsden NHS Foundation Trust - Sutton, Surrey, Not set
Conditions: Germ Cell Tumor, Teratoma, Choriocarcinoma, Germinoma, Mixed Germ Cell Tumor, Yolk Sac Tumor, Childhood Teratoma, Malignant Germ Cell Neoplasm, Extragonadal Seminoma, Non-seminomatous Germ Cell Tumor, Seminoma
Study of Pembrolizumab (MK-3475) Plus Chemotherapy vs Placebo Plus Chemotherapy as Neoadjuvant Therapy and Pembrolizumab vs Placebo as Adjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-522/KEYNOTE-522)
Active Not Recruiting
The purpose of this study is to evaluate the efficacy and safety of pembrolizumab (MK-3475) plus chemotherapy vs placebo plus chemotherapy as neoadjuvant therapy and pembrolizumab vs placebo as adjuvant therapy in participants who have triple negative breast cancer (TNBC).
After a screening phase of approximately 28 days, each participant will receive neoadjuvant study treatment (Pembrolizumab + Chemotherapy OR Placebo + Chemotherapy) based on the randomization schedule for approximately 24 wee... Read More
The purpose of this study is to evaluate the efficacy and safety of pembrolizumab (MK-3475) plus chemotherapy vs placebo plus chemotherapy as neoadjuvant therapy and pembrolizumab vs placebo as adjuvant therapy in participants who have triple negative breast cancer (TNBC).
After a screening phase of approximately 28 days, each participant will receive neoadjuvant study treatment (Pembrolizumab + Chemotherapy OR Placebo + Chemotherapy) based on the randomization schedule for approximately 24 weeks (8 cycles). Each participant will then undergo definitive surgery 3-6 weeks after conclusion of the last cycle of the neoadjuvant study treatment. After definitive surgery, each participant will receive adjuvant study treatment (Pembrolizumab OR Placebo) for approximately 27 weeks (9 cycles). Following adjuvant study treatment, each participant will be monitored for safety, survival and disease recurrence.
The primary study hypothesis is that pembrolizumab is superior to placebo, in combination with chemotherapy, as measured by the rate of Pathological Complete Response (pCR) and/or Event-free Survival (EFS), in participants with locally advanced TNBC. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/08/2025
Locations: Virginia G. Piper Cancer Center Pharmacy - Scottsdale Healthcare ( Site 0089), Scottsdale, Arizona +192 locations
Virginia G. Piper Cancer Center Pharmacy - Scottsdale Healthcare ( Site 0089), Scottsdale, Arizona
Arizona Oncology Associates PC- HOPE ( Site 8001), Tucson, Arizona
Cedars Sinai Medical Center ( Site 0091), Los Angeles, California
Pacific Cancer Care ( Site 0069), Monterey, California
ICRI ( Site 0072), Whittier, California
University of Colorado Cancer Center ( Site 0021), Aurora, Colorado
Yale University School of Medicine ( Site 0054), New Haven, Connecticut
Christiana Hospital ( Site 0029), Newark, Delaware
Univ of Miami-Sylvester Comprehensive Cancer Center- Kendall satellite ( Site 0079), Miami, Florida
The University of Chicago Medical Center ( Site 0047), Chicago, Illinois
North Shore University Health System ( Site 0081), Evanston, Illinois
Orchard Healthcare Research Inc. ( Site 0049), Skokie, Illinois
Goshen Center for Cancer Care ( Site 0010), Goshen, Indiana
University of Iowa Hospital and Clinics ( Site 0038), Iowa City, Iowa
New England Cancer Specialists ( Site 0005), Scarborough, Maine
Henry Ford Hospital ( Site 0003), Detroit, Michigan
Minnesota Oncology Hematology, PA ( Site 8013), Minneapolis, Minnesota
Rutgers Cancer Institute of New Jersey ( Site 0073), New Brunswick, New Jersey
Broome Oncology, LLC ( Site 8002), Johnson City, New York
Nyack Hospital Infusion Center ( Site 0059), Nyack, New York
TriHealth Cancer Institute-Good Samaritan Hospital ( Site 0044), Cincinnati, Ohio
Oncology Hematology Care, Inc. ( Site 8011), Cincinnati, Ohio
Providence Portland Medical Center ( Site 0052), Portland, Oregon
Northwest Cancer Specialists, P.C. ( Site 8008), Portland, Oregon
Magee - Women's Hospital ( Site 0011), Pittsburgh, Pennsylvania
Rhode Island Hospital ( Site 0060), Providence, Rhode Island
The West Clinic, P.C. ( Site 0078), Germantown, Tennessee
Texas Oncology-Austin Central ( Site 8005), Austin, Texas
Parkland Health and Hospital System ( Site 0093), Dallas, Texas
Texas Oncology-Baylor Charles A. Sammons Cancer Center ( Site 8006), Dallas, Texas
Simmons Cancer Center ( Site 0094), Dallas, Texas
UT Southwestern Medical Center ( Site 0030), Dallas, Texas
Moncrief Cancer Institute ( Site 0092), Fort Worth, Texas
Texas Oncology-Memorial City ( Site 8003), Houston, Texas
Houston Methodist Cancer Center ( Site 0013), Houston, Texas
Texas Oncology- Plano East ( Site 8010), Plano, Texas
Texas Oncology-San Antonio Northeast ( Site 8012), San Antonio, Texas
Texas Oncology-Tyler ( Site 8007), Tyler, Texas
University of Virginia ( Site 0022), Charlottesville, Virginia
Virginia Cancer Specialists, PC ( Site 8009), Fairfax, Virginia
Bon Secours Cancer Institute Medical Oncology at St. Mary's ( Site 0033), Midlothian, Virginia
Peninsula Cancer Institute, LLC ( Site 0041), Newport News, Virginia
Virginia Oncology Associates ( Site 8000), Norfolk, Virginia
Kadlec Clinic Hematology and Oncology ( Site 0087), Kennewick, Washington
Seattle Cancer Care Alliance ( Site 0068), Seattle, Washington
Medical Oncology Associates (Summit Cancer Centers) ( Site 0014), Spokane, Washington
YVMH dba Vrigina Mason Memorial/North Star Lodge Cancer Center ( Site 8004), Yakima, Washington
Royal North Shore Hospital ( Site 2000), Sydney, New South Wales
Westmead Hospital ( Site 2002), Sydney, New South Wales
Royal Adelaide Hospital ( Site 2008), Adelaide, South Australia
Cabrini Health ( Site 2009), East Malvern, Victoria
Frankston Hospital ( Site 2010), Franskton, Not set
Royal Brisbane and Women s Hospital ( Site 2003), Herston, Not set
St John of God Subiaco Hospital ( Site 2006), Perth, Not set
Hospital Nossa Senhora da Conceicao ( Site 0203), Porto Alegre, Rio Grande Do Sul
UOPECCAN - Uniao Oeste Paranaense de Estudos e Combate ao Cancer ( Site 0206), Cascavel, Not set
Universidade de Caxias do Sul ( Site 0201), Caxias do Sul, Not set
Hospital Erasto Gaertner ( Site 0207), Curitiba, Not set
Instituto do Cancer do Ceara ( Site 0205), Fortaleza, Not set
Hospital Araujo Jorge ( Site 0204), Goiania, Not set
Hospital Sao Lucas da PUCRS ( Site 0200), Porto Alegre, Not set
Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto ( Site 0208), Sao Jose do Rio Preto, Not set
Instituto do Cancer de Sao Paulo - ICESP ( Site 0211), Sao Paulo, Not set
Tom Baker Cancer Centre ( Site 0105), Calgary, Alberta
The Ottawa Hospital - Cancer Care ( Site 0100), Ottawa, Ontario
Princess Margaret Cancer Centre ( Site 0103), Toronto, Ontario
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0106), Montreal, Quebec
Jewish General Hospital ( Site 0101), Montreal, Quebec
CIUSSS de l'Estrie-CHUS ( Site 0102), Sherbrooke, Quebec
CHU de Quebec Universite Laval - Hopital du Saint-Sacrement ( Site 0104), Quebec, Not set
Oncomedica S.A. ( Site 0404), Monteria, Cordoba
Oncologos del Occidente S.A. ( Site 0405), Pereira, Risaralda
Hospital Universitario San Ignacio ( Site 0401), Bogota, Not set
Instituto Nacional de Cancerologia [Bogota-Colombia] ( Site 0403), Bogota, Not set
Hemato Oncologos S.A. ( Site 0400), Cali, Not set
Instituto De Cancerologia S.A. ( Site 0406), Medellin, Not set
CHU Jean Minjoz ( Site 0917), Besancon, Not set
Polyclinique Bordeaux Nord Aquitaine ( Site 0911), Bordeaux, Not set
Centre Francois Baclesse ( Site 0907), Caen, Not set
Centre Jean Perrin ( Site 0903), Clermont-Ferrand Cedex 01, Not set
Clinique Victor Hugo ( Site 0901), Le Mans, Not set
Hopital prive du Confluent ( Site 0902), Nantes, Not set
Institut Curie ( Site 0909), Paris, Not set
Hopital Saint Louis ( Site 0908), Paris, Not set
Hopital Diaconesses Croix Saint Simon ( Site 0905), Paris, Not set
CHU de la Miletrie Poitiers ( Site 0913), Poitiers, Not set
Institut Claudius Regaud IUCT Oncopole ( Site 0914), Toulouse Cedex 9, Not set
HELIOS Klinikum Berlin-Buch ( Site 1005), Berlin, Not set
Gynaekologisches Zentrum ( Site 1004), Bonn, Not set
Universitaetsklinikum Erlangen ( Site 1001), Erlangen, Not set
Kliniken Essen Mitte ( Site 1012), Essen, Not set
Universitaetsklinik und Poliklinik Halle/Saale ( Site 1008), Halle, Not set
Universitaetsklinikum Hamburg-Eppendorf ( Site 1007), Hamburg, Not set
Klinikum der Universit. Muenchen ( Site 1002), Muenchen, Not set
Caritasklinik St. Theresia ( Site 1011), Saarbruecken, Not set
Universitaets-Frauenklinik Tuebingen ( Site 1003), Tubingen, Not set
Bon Secours Hospital ( Site 1551), Cork, Not set
St Vincents University Hospital ( Site 1550), Dublin, Not set
Oncology institute ( Site 1601), Beer Sheva, Not set
Assaf Harofeh MC ( Site 1605), Beer Yaakov-Zerifin, Not set
Hadassah Ein Karem - Sharett Institute of Oncology ( Site 1600), Jerusalem, Not set
Rabin-Medical Center ( Site 1604), Petah Tikva, Not set
Sheba Medical Center ( Site 1602), Ramat-Gan, Not set
Sourasky Medical Center ( Site 1603), Tel Aviv, Not set
Istituto Scientifico Romagnolo per Studio e Cura Tumori IRST ( Site 1101), Meldola, FC
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia ( Site 1103), Brescia, Not set
Ospedale San Luca, AZIENDA USL2 TOSCANA NORD OVEST ( Site 1105), Lucca, Not set
Ospedale Civile di Macerata ( Site 1104), Macerata, Not set
Istituto Europeo di Oncologia ( Site 1106), Milano, Not set
Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 1102), Napoli, Not set
Aichi Cancer Center Hospital ( Site 2502), Nagoya, Aichi
National Cancer Center Hospital East ( Site 2518), Kashiwa, Chiba
National Hospital Organization Hokkaido Cancer Center ( Site 2512), Sapporo, Hokkaido
Hyogo College of Medicine Hospital ( Site 2506), Nishinomiya, Hyogo
Tokai University Hospital ( Site 2517), Isehara, Kanagawa
St. Marianna University School of Medicine Hospital ( Site 2516), Kawasaki, Kanagawa
Kindai University Hospital ( Site 2507), Osakasayama, Osaka
Saitama Medical University International Medical Center ( Site 2513), Hidaka, Saitama
Saitama Cancer Center ( Site 2510), Kitaadachi-gun, Saitama
Shizuoka Cancer Center Hospital and Research Institute ( Site 2514), Sunto-gun, Shizuoka
Chiba Cancer Center ( Site 2519), Chiba, Not set
Hiroshima City Hiroshima Citizens Hospital ( Site 2501), Hiroshima, Not set
Social medical corporation Hakuaikai Sagara Hospital ( Site 2508), Kagoshima, Not set
Kumamoto University Hospital ( Site 2515), Kumamoto, Not set
National Hospital Organization Osaka National Hospital ( Site 2505), Osaka, Not set
National Cancer Center Hospital ( Site 2500), Tokyo, Not set
St.Luke's International Hospital ( Site 2511), Tokyo, Not set
Toranomon Hospital ( Site 2503), Tokyo, Not set
The Cancer Institute Hospital of JFCR ( Site 2509), Tokyo, Not set
Seoul National University Hospital ( Site 2101), Seoul, Not set
Severance Hospital Yonsei University Health System ( Site 2100), Seoul, Not set
Asan Medical Center ( Site 2102), Seoul, Not set
Samsung Medical Center ( Site 2103), Seoul, Not set
Mazowiecki Szpital Onkologiczny ( Site 1713), Wieliszew, Mazowieckie
Centrum Onkologii Instytut im. Marii Skłodowskiej Curie ( Site 1717), Gliwice, Slaskie
Centrum Onkologii im. Prof. Franciszka Lukaszczyka ( Site 1708), Bydgoszcz, Not set
Centrum Onkologii im. Prof. Franciszka Lukaszczyka ( Site 1712), Bydgoszcz, Not set
Szpital Morski im. PCK. Szpitale Pomorskie Sp. Z o.o ( Site 1701), Gdynia, Not set
Centrum Onkologii Instytut im. Marii Sklodowskiej Curie ( Site 1719), Krakow, Not set
Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli ( Site 1700), Lublin, Not set
Dolnoslaskie Centrum Onkologii. ( Site 1702), Wroclaw, Not set
Fundacao Champalimaud ( Site 2444), Lisboa, Not set
Hospital de Santa Maria, E.P.E. ( Site 2445), Lisboa, Not set
Instituto Portugues de Oncologia Do Porto Francisco Gentil E.P.E. ( Site 2446), Porto, Not set
Arkhangelsk Clinical Oncological Dispensary ( Site 1810), Arkhangelsk, Not set
Chelyabinsk Regional Clinical Oncological Dispensary ( Site 1805), Chelyabinsk, Not set
Republican Clinical Oncology Dispensary of Tatarstan MoH ( Site 1806), Kazan, Not set
Russian Oncological Research Center n.a. N.N.Blokhin of MoH ( Site 1801), Moscow, Not set
GBU RO Regional Clinical Oncological Dispensary ( Site 1808), Ryazan, Not set
Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 1803), Saint Petersburg, Not set
Republican Clinical Oncology Dispensary of Republic of Bashkortostan ( Site 1804), Ufa, Not set
National Cancer Centre Singapore ( Site 2600), Singapore, Not set
ICO L Hospitalet ( Site 1305), Hospitalet de Llobregat, Barcelona
Hospital Quiron de Madrid ( Site 1303), Pozuelo de Alarcon, Madrid
Hospital del Mar ( Site 1306), Barcelona, Not set
Instituto Oncologico Baselga.Hospital Quiron. ( Site 1312), Barcelona, Not set
Hospital General Universitari Vall d Hebron ( Site 1301), Barcelona, Not set
Hospital Universitario Reina Sofia ( Site 1304), Cordoba, Not set
Hospital Universitario Ramon y Cajal ( Site 1300), Madrid, Not set
Complejo Hospitalario Universitario de Santiago ( Site 1308), Santiago de Compostela, Not set
Hospital Universitario Virgen del Rocio ( Site 1314), Sevilla, Not set
Hospital Clinico Univ de Valencia ( Site 1313), Valencia, Not set
Linkopings Universitetssjukhus ( Site 1402), Linkoping, Not set
Karolinska Universitetssjukhuset Solna ( Site 1404), Solna, Not set
Norrlands Universitetssjukhus ( Site 1401), Umea, Not set
Akademiska Sjukhuset ( Site 1403), Uppsala, Not set
Taipei Veterans General Hospital ( Site 2302), Taipei, Beitou
National Cheng Kung University Hospital ( Site 2305), Tainan, Not set
National Taiwan University Hospital ( Site 2301), Taipei, Not set
MacKay Memorial Hospital ( Site 2303), Taipei, Not set
Koo Foundation Sun Yat-Sen Cancer Center ( Site 2304), Taipei, Not set
Linkou Chang Gung Memorial Hospital ( Site 2300), Taoyuan, Not set
Samsun Ondokuz Mayıs Universitesi Tıp Fakultesi Hastanesi ( Site 1910), Samsun, Atakum
Adana Acıbadem Hospital Department of Medical Oncology ( Site 1906), Adana, Not set
Baskent Unıversity Adana Kısla Hospital ( Site 1903), Adana, Not set
Hacettepe Universitesi Tip Fakultesi Hastanesi ( Site 1912), Ankara, Not set
Abdurrahman Yurtaslan Oncology Training and Research Hospital ( Site 1909), Ankara, Not set
Ozel Medicana International Ankara Hastanesi ( Site 1915), Ankara, Not set
Antalya Memorial Hospital Department of Medical Oncology ( Site 1908), Antalya, Not set
Trakya University Medical Faculty Balkan Oncology Hospital ( Site 1901), Edirne, Not set
Acibadem Altunizade Hastanesi ( Site 1900), Istambul, Not set
İstanbul University Cerrahpaşa Medical Faculty ( Site 1904), Istanbul, Not set
Amerikan Hospital Medical ( Site 1902), Istanbul, Not set
Memorial Sisli Hastanesi ( Site 1913), Istanbul, Not set
Ege University Medical Faculty Tulay Aktas Oncology Hospital ( Site 1905), Izmir, Not set
Izmir Medical Park Hospital Department of Medical Oncology ( Site 1907), Izmir, Not set
Colchester General Hospital ( Site 1508), Colchester, Essex
Barts Cancer Institute ( Site 1500), London, Not set
St George s Hospital ( Site 1516), London, Not set
Maidstone Hospital ( Site 1511), Maidstone, Not set
The James Cook University Hospital ( Site 1515), Middlesbrough, Not set
Nottingham University Hospitals NHS Trust ( Site 1505), Nottingham, Not set
Royal Cornwall Hospitals NHS Trust ( Site 1504), Truro, Not set
Conditions: Triple Negative Breast Neoplasms
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