The city of Norfolk, Virginia, currently has 2 active clinical trials seeking participants for Parkinson's Disease research studies.
Dipraglurant (ADX48621) for the Treatment of Patients With Parkinson's Disease Receiving Levodopa-based Therapy
Recruiting
This study is designed to evaluate the safety and efficacy of dipraglurant in PD patients with dyskinesia (randomized 1:1 to receive active or placebo) for 12 weeks (1 week at 150 mg per day and 11 weeks at 300 mg per day). The primary efficacy assessment will be based on the Unified Dyskinesia Rating Scale (UDysRS). Patients who complete the 12-week blinded treatment period may have the option to roll into an open-label safety extension study for an additional 12-month treatment period.
Gender:
All
Ages:
Between 30 years and 85 years
Trial Updated:
05/18/2022
Locations: Meridian Clinical Research (Norfolk, Virginia), Norfolk, Virginia
Conditions: Parkinson Disease, Dyskinesia, Drug-Induced, Dyskinesias
Self-Reports of Executive Functions in Persons With Parkinson's Disease and Their Significant Others
Recruiting
The investigators are conducting a study to compare the self-reports of executive functions (that is to say, what role cognitive processes such as working memory and attention) in persons with Parkinson's Disease to the reports of executive functions completed by their significant others. To conduct this study, the investigators need the participation of persons who are diagnosed with Parkinson's Disease and their significant others.
Gender:
All
Ages:
Between 30 years and 79 years
Trial Updated:
06/15/2021
Locations: Old Dominion University, Norfolk, Virginia
Conditions: Parkinsonism or Parkinson's Disease Nos