There are currently 587 clinical trials in Richmond, Virginia looking for participants to engage in research studies. Trials are conducted at various facilities, including Virginia Commonwealth University, Virginia Commonwealth University/Massey Cancer Center, GSK Investigational Site and Virginia Cancer Institute. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
NCT03860883
Recruiting
Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with stage II primary invasive cutaneous melanomas (AJCC 8th edition) to determine differences in disease-free survival. A reduction in margins is expected to improve patient quality of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: VCU Massey Cancer Center, Richmond, Virginia
Conditions: Cutaneous Melanoma, Stage II
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Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients
NCT05586971
Recruiting
The aim of this 12-month randomized multi-regional double-blind parallel group allopurinol and placebo-controlled phase 3 study is to assess the efficacy and safety of three different doses of Tigulixostat in gout patients with hyperuricemia.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
10/17/2023
Locations: Dominion Medical Associates, Inc., Richmond, Virginia
Conditions: Gout, Hyperuricemia, Gout Flare, Tophi
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Caring for Caregivers and People Living With Dementia Under Home-Based Primary Care
NCT05849259
Recruiting
The goal of this clinical trial is to develop a dementia care intervention for persons receiving home-based primary care (HBPC) and living with dementia (PLWD) and their caregivers, and test the feasibility of implementing the intervention in HBPC practices to ultimately improve outcomes of PLWD and their caregivers. The main aims are to: Develop and refine HBPC Dementia Care Quality at Home Establish feasibility (primary outcome), acceptability, and fidelity of HBPC Dementia Care Quality at H... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/16/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Dementia, Quality of Life, Caregiver Stress
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Myocardial Perfusion and Fibrosis in Cancer Survivors
NCT03191461
Recruiting
This is a cross-sectional pilot study. The investigators seek to obtain early information pertaining to the relationship between measurements of myocardial perfusion reserve and myocardial fibrosis after receipt of Anthracycline-based chemotherapy (≥2 years prior).
Gender:
All
Ages:
Between 21 years and 85 years
Trial Updated:
10/13/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Myocardial Fibrosis, Myocardial Injury, Chemotherapeutic Toxicity
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Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients
NCT06077214
Recruiting
Liposomal bupivacaine (trade name Exparel) is a local analgesic that is designed to produce more long-term pain control. Bupivacaine, a widely used local analgesic, is stored within liposomes, which break down in soft tissue over time. Typical length of therapeutic effect for standard bupivacaine is up to 6 hours. The liposomal formulation of bupivacaine, however, has a length of therapeutic effect of up to 72 hours. Typical post-operative incisional pain is known to last for several days in mos... Read More
Gender:
All
Ages:
Between 13 years and 18 years
Trial Updated:
10/12/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Bariatric Surgery Candidate, Post-operative Pain
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Mindful Moms Randomized Control Trial
NCT04886856
Recruiting
The purpose of this study is to test whether a program called "Mindful Moms" can be helpful for specific measures of mood and health in pregnant women with depressive symptoms, compared to group-based education workshops.
Gender:
Female
Ages:
18 years and above
Trial Updated:
10/10/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Depression
Register for Updates
Saroglitazar Magnesium 4 mg for NASH in People Living With HIV in the US
NCT05211284
Recruiting
Saroglitazar Magnesium 4 mg for NASH in People Living with HIV in the US
Gender:
All
Ages:
18 years and above
Trial Updated:
10/06/2023
Locations: Zydus research site 8, Richmond, Virginia
Conditions: Nonalcoholic Steatohepatitis
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Effectiveness of Remote Foot Temperature Monitoring
NCT05728411
Recruiting
Diabetic foot ulcers are common, debilitating, and costly complications of diabetes, disproportionately impacting Black and rural Veterans. Forty percent of individuals have an ulcer recurrence within a year of ulcer healing and 65% within 5 years. Monitoring plantar foot temperatures is one of the few interventions that reduces the risk of ulcer recurrence. Despite the evidence, adoption has been poor because the original procedures, including the use of handheld thermometers, were burdensome a... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
10/04/2023
Locations: Hunter Holmes McGuire VA Medical Center, Richmond, VA, Richmond, Virginia
Conditions: Diabetic Foot
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A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease
NCT05655520
Recruiting
The primary purpose of the study is to evaluate the safety and tolerability of SAGE-718 softgel lipid capsule in participants with Huntington's Disease (HD)
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
09/29/2023
Locations: Sage Investigational Site, Richmond, Virginia
Conditions: Huntington Disease
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Post-Approval Study of the TREO Abdominal Stent-Graft System
NCT04697784
Recruiting
The purpose of this study is to determine the long-term performance of the TREO Abdominal Stent-Graft as a treatment for patients with Infrarenal Abdominal Aortic Aneurysms or Aorto-iliac Aneurysms.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/27/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Abdominal Aortic Aneurysm
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NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors
NCT04656496
Recruiting
Pediatric cancer survivors are at an increased risk of excessive weight gain and reduced exercise behaviors with the potential for this risk to worsen over time. With over 80% of pediatric cancer patients living to adulthood, many pediatric cancer survivors experience long-term health consequences such as heart disease - the leading cause of death in this population. The purpose of this clinical research study is to teach parents/caregivers skills that will help prevent and reduce the problems... Read More
Gender:
All
Ages:
Between 5 years and 14 years
Trial Updated:
09/26/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Obesity, Childhood, Cancer, Survivorship
Register for Updates
Diagnostic Stewardship for Ventilator Associated Pneumonia
NCT05989269
Recruiting
The goal of this pragmatic cluster-randomized crossover trial is to test if less unnecessary antibiotics are prescribed when the lab reports respiratory culture test results in a specific way for patients who have respiratory cultures obtained, but do not meet clinical criteria for ventilator associated pneumonia (VAP). The main question it aims to answer is: Does a modified culture reporting intervention reduce unnecessary antibiotics for ventilated patients in the intensive care unit (ICU)? Re... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/20/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Ventilator Associated Pneumonia
Register for Updates