Arlington Aging Study
NCT06857877
Recruiting
The goal of this observational study is to learn about the mechanisms causing functional decline with age, using exercise science, neuroscience, and remote monitoring. Specific aims include: Aim 1: Advance knowledge of the biology of aging and its impact on the prevention, progression, and prognosis of disease and disability. Aim 2: Determine the effects of personal and societal factors on aging. Aim 3: Examine the influence of racial/ethnic and sex differences on the biology of aging and it... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/27/2025
Locations: University of Texas Arlington, Arlington, Texas
Conditions: Aging
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Cycle and Stroke With Biofeedback for Power Symmetry
NCT06857916
Recruiting
To determine changes in power symmetry, gait symmetry, and functional outcomes for participants' poststroke (Inpatient Rehabilitation Facility) after participating in an intervention using a recumbent cycle with power biofeedback (BFB). To determine how this intervention can impact gait asymmetry, a common disorder poststroke secondary to hemiparesis. Gait asymmetry is a difficult impairment to treat because it is difficult for both therapists and patients to perceive. Training with BFB allows f... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/27/2025
Locations: University Health, Neilsen Rehabilitation Hospital, Salt Lake City, Utah
Conditions: Stroke
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Promoting Active Therapy: Path to Wellness
NCT06858189
Recruiting
This project will examine changes in depression and anxiety following a 10-week intervention promoting nature-based physical activity in mental health settings. We will recruit ten licensed therapists whose caseload includes adults with depression and anxiety. Following a training by our team, each participating therapist will recruit six clients, who will be randomly assigned to the intervention or control condition. Clients in the intervention condition will engage in walk-and-talk therapy out... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/27/2025
Locations: Kansas State University, Manhattan, Kansas
Conditions: Depression, Anxiety, Physical Activity, Time in Nature, Self-Efficacy, Feasibility Pilot Study
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Evaluating AI-Generated Plain Language Summaries on Patient Comprehension of Ophthalmology Notes Among English-Speaking Patients
NCT06859216
Recruiting
This clinical trial is testing whether plain language summaries made by artificial intelligence help people understand their eye doctor's notes better. Adults receiving eye care at the Jules Stein Eye Institute will get either the usual medical notes or a note with the addition of an AI-generated summary that explains the information in simple, everyday words. Participants will then answer a short survey and receive a follow-up call to share how clear the information was, how well they understoo... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2025
Locations: UCLA, Los Angeles, California
Conditions: Ophthalmic Disease, Artifical Intelligence, Large Language Model
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Cochlear Implant Speech in Noise Processing
NCT06860152
Recruiting
The study will help us in understanding the neural mechanisms by which listeners with a cochlear implant detect speech in noisy environments.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
02/27/2025
Locations: University of Iowa, Iowa City, Iowa
Conditions: Hearing Loss, Adult-Onset, Speech Intelligibility, Hearing Loss, Extreme
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Specimen and Data Study for Ovarian Cancer Early Detection and Prevention
NCT00005095
Recruiting
RATIONALE: To improve strategies for detection and prevention of early-stage disease. PURPOSE: This research study is collecting specimens and data to develop better methods for early detection and prevention of ovarian cancer among the high risk population and those who have the disease.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
02/26/2025
Locations: Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago, Illinois
Conditions: Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2), Ovarian Cancer, Sarcoma, Uterine Leiomyomata, Vaginal Cancer, Vulvar Cancer
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Prospective Evaluation of Adjusted Body Weight Dosing of Acyclovir in Obesity
NCT02879630
Recruiting
Patients receiving acyclovir as standard of care will be enrolled into this study. The currently recommended dosing strategy at our institution for obese patients is to receive intravenous acyclovir dosed per an adjusted body weight \[IBW + 0.4(TBW-IBW)\]. They will have blood drawn once prior to the first dose of acyclovir and 10 times thereafter, over a total time period of 12 hours. These patients will already be hospitalized for other reasons, and will not be required to make additional trip... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2025
Locations: West Virginia University Hospitals, Morgantown, West Virginia
Conditions: Obesity
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Registry of Patients With Takotsubo Syndrome
NCT03663348
Recruiting
Takotsubo syndrome is a condition which mimics acute myocardial infarction, and is diagnosed in 1.5% to 2.2% of patients referred to hospital with suspected acute coronary syndrome. It is also known as broken heart syndrome, takotsubo cardiomyopathy, stress cardiomyopathy and apical ballooning cardiomyopathy, among other names. The pathogenesis of this disorder is not well understood. Possible mechanisms include catecholamine excess, coronary artery spasm, microvascular dysfunction, among others... Read More
Gender:
ALL
Ages:
Between 18 years and 110 years
Trial Updated:
02/26/2025
Locations: NYU School of Medicine, New York, New York
Conditions: Takotsubo Cardiomyopathy, Broken Heart Syndrome, Tako-tsubo Cardiomyopathy
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Wound Closure Study in Carpal Tunnel and Trigger Finger Surgery
NCT03781141
Recruiting
Does a difference in patient satisfaction and cosmetic outcome exist between wound closure with absorbable or non-absorbable sutures.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Carpal Tunnel Syndrome, Trigger Finger
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Lidocaine Infusion in Pancreatic Cancer
NCT04048278
Recruiting
This study elucidates the effects of the intravenous (IV) lidocaine infusion on the biology of pancreatic circulating tumor cells (CTCs) isolated from patients undergoing robotic pancreatectomy for all types of pancreatic cancer. A prospective randomized controlled double blinded trial design will be used for the proposed study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2025
Locations: University of Illnois at Chicago, Chicago, Illinois
Conditions: Pancreatic Cancer
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Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
NCT04427384
Recruiting
The objectives of this registry study are to evaluate real-world clinical outcomes and patient reported outcomes that measure the effectiveness and safety of STaRT.
Gender:
ALL
Ages:
All
Trial Updated:
02/26/2025
Locations: HonorHeath Scottsdale Osborn Medical Center, Phoenix, Arizona +47 locations
Conditions: Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma
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POCUS: Hemostatic Potential and Joint Health in Patients With Severe Hemophilia A on Novel Replacement Therapies
NCT04690322
Recruiting
This is a prospective, randomized control trial in which each patient will be randomly assigned to receive either extended half-life factor VIII based replacement therapy or non-FVIII based replacement therapy, which are both standard of care treatment for persons with Hemophilia A.
Gender:
ALL
Ages:
17 years and below
Trial Updated:
02/26/2025
Locations: The University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Hemophilia A, Factor VIII
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