All Clinical Trials

A listing of 23118 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Conditions:

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A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

NCT04064060

Recruiting

A Phase 3b, open-label, single-arm, rollover study to evaluate the long-term safety of luspatercept, to the following participants: * Participants receiving luspatercept on a parent protocol at the time of their transition to the rollover study, who tolerate the protocol-prescribed regimen in the parent trial and, in the opinion of the investigator, may derive clinical benefit from continuing treatment with luspatercept * Participants in the follow-up phase previously treated with luspatercept or placebo in the parent protocol will continue into long-term post-treatment follow-up in the rollover study until the follow-up commitments are met * The study design is divided into the Transition Phase, Treatment Phase and Follow-up Phase. Participants will enter transition phase and depending on their background will enter either the treatment phase or the Long-term Post-treatment Follow-up (LTPTFU) phase * Transition Phase is defined as one Enrollment visit * Treatment Phase: For participants in luspatercept treatment the dose and schedule of luspatercept in this study will be the same as the last dose and schedule in the parent luspatercept study. This does not apply to participants that are in long-term follow-up from the parent protocol * Follow-up Phase includes: - 42 Day Safety Follow-up Visit * During the Safety Follow up, the participants will be followed for 42 days after the last dose of luspatercept, for the assessment of safety-related parameters and adverse event (AE) reporting - Long-term Post-treatment Follow-up (LTPTFU) Phase * Participants will be followed for overall survival every 6 months for at least 5 years from first dose of luspatercept in the parent protocol, or 3 years of post-treatment from last dose, whichever occurs later, or until death, withdrawal of consent, study termination, or until a subject is lost to follow-up. Participants will also be monitored for progression to AML or any malignancies/pre-malignancies. New anticancer or disease related therapies should be collected at the same time schedule Participants transitioning from a parent luspatercept study in post-treatment follow-up (safety or LTPTFU) will continue from the same equivalent point in this rollover study. The ACE-536-LTFU-001 rollover study will be terminated, and relevant participants will discontinue from the study when all participants fulfill 5 years on the study, including treatment and follow-up. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: Childrens Hospital Los Angeles RHU, Los Angeles, California +142 locations

Childrens Hospital Los Angeles RHU, Los Angeles, California

Local Institution - 971, Oakland, California

Local Institution - 978, Stanford, California

Local Institution - 975, Tampa, Florida

Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois

Boston Children's Hospital, Boston, Massachusetts

Local Institution - 961, Detroit, Michigan

Local Institution - 969, New York, New York

Local Institution - 967, Cleveland, Ohio

Local Institution - 972, Philadelphia, Pennsylvania

Vanderbilt - Ingram Cancer Center, Nashville, Tennessee

The University of Texas - MD Anderson Cancer Center, Houston, Texas

Local Institution - 100, South Brisbane, Queensland

Royal Adelaide Hospital, Adelaide, South Australia

Local Institution - 102, Clayton, Victoria

Royal Prince Alfred Hospital, Camperdown, Not set

Local Institution - 182, Brasschaat, Not set

Local Institution - 180, Brugge, Not set

Local Institution - 183, Ghent, Not set

Local Institution - 184, Leuven, Not set

Local Institution - 220, Boulevard, Sofia

Local Institution - 221, Plovdiv, Not set

Local Institution - 262, Toronto, Ontario

University Health Network, Toronto, Ontario

Local Institution - 263, Toronto, Ontario

Local Institution - 131, Beijing, Beijing

Local Institution - 135, Guangzhou, Guangdong

Local Institution - 132, Shanghai, Shanghai

Local Institution - 134, Chengdu, Sichuan

Local Institution - 130, Tianjin, Tianjin

Local Institution - 133, Hangzhou, Zhejiang

Local Institution - 305, Angers, Not set

Local Institution - 300, Creteil, Not set

Local Institution - 310, La Tronche, Not set

Local Institution - 306, Lille, Not set

Local Institution - 301, Marseille Cedex 9, Not set

Local Institution - 302, Paris, Not set

Local Institution - 307, Pessac Cedex, Not set

Local Institution - 304, Pierre Benite cedex, Not set

Local Institution - 308, Strasbourg, Not set

Local Institution - 309, Toulouse Cedex 9, Not set

Local Institution - 303, Tours, Not set

Local Institution - 341, Berlin, Not set

Universitatsklinikum Carl Gustav Carus an der TU Dresden, Dresden, Not set

Local Institution - 345, Duesseldorf, Not set

Local Institution - 346, Dusseldorf, Not set

Local Institution - 343, Halle, Not set

Local Institution - 342, Hamburg, Not set

Local Institution - 344, Hannover, Not set

Local Institution - 349, Leipzig, Not set

Local Institution - 340, Mainz, Not set

Klinikum Rechts der Isar der Technischen Universitaet Muenchen, München, Not set

Aghia Sophia' Children's General Hospital of Athens, Athens, Not set

Laiko General Hospital of Athens - Center of Thalassemia, Athens, Not set

Local Institution - 384, Athens, Not set

Local Institution - 383, Rio Patras, Not set

General Hospital of Thessaloniki Hippokration, Thessaloniki, Not set

Local Institution - 425, Afula, Not set

Rambam Health Corporation, Haifa, Not set

Local Institution - 422, Jerusalem, Not set

Local Institution - 424, Jerusalem, Not set

Local Institution - 421, Nahariya, Not set

Local Institution - 423, Petah Tikva, Not set

Local Institution - 478, Firenze, Toscana

Local Institution - 471, Firenze, Toscana

Local Institution - 470, Allessandria, Not set

Local Institution - 464, Bologna, Not set

Local Institution - 466, Brindisi, Not set

Local Institution - 477, Cagliari, Not set

Local Institution - 462, Ferrara, Not set

Ente Ospedaliero Ospedali Galliera - Centro della Microcitemia e delle Anemie Congenite, Genoa, Not set

Local Institution - 473, Lecce, Not set

Maggiore Polyclinic Hospital, IRCCS Ca' Granda, Milano, Not set

Local Institution - 479, Modena, Not set

AORN A Cardarelli, Napoli, Not set

AOU dell'Universita degli Studi della Campania Luigi Vanvitelli, Napoli, Not set

Azienda Ospedaliero Universitaria S. Luigi Gonzaga, Orbassano, Not set

Local Institution - 469, Pavia, Not set

Local Institution - 468, Reggio Di Calabria, Not set

Local Institution - 465, Roma, Not set

Local Institution - 474, Rozzano, Not set

Ospedale di Circolo di Varese, Varese, Not set

Local Institution - 463, Verona, Not set

Local Institution - 610, Nagoya, Aichi

Local Institution - 601, Kamogawa, Chiba

Matsuyama Red Cross Hospital, Matsuyama, Ehime

Ogaki Municipal Hospital, Ogaki, Gifu

Japanese Red Cross Society Himeji Hospital, Himeji, Hyogo

Local Institution - 605, Hitachi, Ibaraki

Kitasato University Hospital, Sagamihara, Kanagawa

Local Institution - 0979, Sendai, Miyagi

Tohoku University Hospital, Sendai, Miyagi

Local Institution - 611, Nagasaki-shi, Nagasaki

Japanese Red Cross Medical Center, Shibuya City, Tokyo

NTT Medical Center Tokyo, Shinagawa City, Tokyo

Local Institution - 612, Chiba, Not set

Shonan Kamakura General Hospital, Kamakura, Not set

Osaka Metropolitan University Hospital, Osaka, Not set

Local Institution - 604, Osaka, Not set

Chronic Care Center, Hazmieh, Not set

Local Institution - 545, Johor Bahru, Johor

Hospital Sultanah Bahiyah, Alor Setar, Kedah

Hospital Raja Permaisuri Bainun, Ipoh, Perak

Queen Elizabeth Hospital, Kota Kinabalu, Sabah

Hospital Umum Sarawak, Kuching, Sarawak

University Malaya Medical Centre, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur

Local Institution - 580, Amsterdam, Not set

Local Institution - 681, Barakaldo, Not set

Local Institution - 686, Barcelona, Not set

Local Institution - 685, Barcelona, Not set

Local Institution - 687, Madrid, Not set

Local Institution - 682, Oviedo, Not set

Local Institution - 684, Salamanca, Not set

Local Institution - 680, Seville, Not set

Local Institution - 683, Valencia, Not set

Local Institution - 720, Goteborg, Not set

Local Institution - 722, Lund, Not set

Local Institution - 721, Stockholm, Not set

Kaohsiung Medical University Hospital, Kaohsiung, San Ming Dist., Not set

China Medical University Hospital, Taichung, Not set

Local Institution - 761, Taipei, Not set

Chulalongkorn University Faculty of Medicine - King Chulalongkorn Memorial Hospital, Bangkok, Not set

Siriraj Hospital Mahidol University, Bangkok, Not set

Chiang Mai University - Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Not set

University Hospital Farhat Hached, Sousse, Not set

Bone Marrow Transplant Center, Tunis, Not set

Aziza Othmana Hospital, Tunis, Not set

Military Hospital of Tunis, Tunis, Not set

Acibadem Adana Hospital, Adana, Not set

Local Institution - 885, Ankara, Not set

Local Institution - 882, Istanbul, Not set

Local Institution - 884, Istanbul, Not set

Local Institution - 880, Izmir, Not set

Local Institution - 883, Mersin, Not set

Local Institution - 925, Aberdeen, Not set

Local Institution - 921, Leeds, Not set

Local Institution - 923, London, Not set

Whittington Hospital, London, Not set

University College London Hospitals NHS Foundation Trust - University College Hospital, London, Not set

Local Institution - 928, London, Not set

Kings College Hospital, London, Not set

Local Institution - 929, Oxford, Not set

Local Institution - 926, Sutton in Ashfield, Not set

Conditions: Myelodysplastic Syndromes (MDS), Beta-thalassemia, Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis

Learn More ›

P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma

NCT04960579

Recruiting

Phase 1 study comprised of open-label, dose escalation, multiple cohorts of P-BCMA-ALLO1 allogeneic T stem cell memory (Tscm) CAR-T cells in subjects with relapsed / refractory Multiple Myeloma (RRMM).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: City of Hope, Goodyear, Arizona +20 locations

Conditions: Multiple Myeloma

Learn More ›

@neurIST : Intregrated Biomedical Informatics for the Management of Cerebral Aneurysms

NCT05526352

Recruiting

The primary aim of the SwissNeuroFoundation AneurysmDataBase Project is to implement information technology based tools to create and use a holistic reference database specific to intracranial aneurysms (IA). The SwissNeuroFoundation AneurysmDataBase are concerned with generating the data with which to populate this database. The purpose for populating the database are to: * Screen for and evaluate markers of risk for intracranial aneurysm formation and aneurysm rupture. Are considered as mar... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: University of California, San Francisco, California +20 locations

Conditions: Intracranial Aneurysm

Learn More ›

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

NCT05954312

Recruiting

A FIH dose escalation and dose expansion study to evaluate VVD-130037 in participants with advanced solid tumors as a single agent, in combination with docetaxel, and in combination with paclitaxel.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: Mayo Clinic Jacksonville, Jacksonville, Florida +14 locations

Conditions: Advanced Solid Tumors

Learn More ›

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130850 in Participants With Advanced Solid and Hematologic Tumors

NCT06188208

Recruiting

A FIH study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of VVD-130850, as single agent and in combination with checkpoint inhibition, in participants with advanced solid and hematologic tumors.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: California Research Institute, Los Angeles, California +19 locations

Conditions: Advanced Solid Tumors, Advanced Hematologic Tumors

Learn More ›

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

NCT06468228

Recruiting

Hidradenitis suppurativa (HS) is a chronic and often painful inflammatory skin disease which includes the forming of lumps, abscesses and scars in areas of the skin such as under the breasts, under armpits, inner thighs, groin and buttocks. This study will compare lutikizumab versus placebo for the treatment of adult and adolescent participants with the signs and symptoms of moderate to severe HS . Lutikizumab is an investigational drug being developed for the treatment of HS. During Period 1 of the study, participants will placed in 1 of 2 groups called treatment arms. There is a 1 in 2 chance that participants will be assigned to placebo. Around 1280 adult and adolescent participants with moderate to severe HS will be enrolled in the study at approximately 275 sites world wide. During Period 2, participants that were part of the lutikizumab treatment arm in Period 1 will be re-randomized to 1 of 2 lutikizumab treatment arms. Participants that were part of the Placebo arm in Period 1 will start Period 2 with an initiation of lutikizumab followed by a re-randomization to 1 of 2 lutikizumab treatment arms. In Period 1, participants will receive subcutaneous injections of lutikizumab or placebo every week for 16 weeks. In Period 2, participants that were randomized to lutikizumab in Period 1 will receive subcutaneous injections of lutikizumab every week or every other week for 36-weeks. Participants that were randomized to the placebo arm in Period 1 will receive subcutaneous injections of lutikizumab every week for 16 weeks, then either every week or every other week for 20 weeks. Period 3 is the Long Term Extentsion (LTE) and through Week 68, participants will continue to receive lutikizumab SC using the same assigned dosing regimen from the end of Period 2 for 16 weeks followed by open-label lutikizumab EOW for 140 weeks. Participants in the US that complete Periods 1 \& 2 will have the option to enroll in a 156-week open-label Sub-Study that will assess the long term safety and efficacy of lutikizumab in a prefilled pen. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires and diaries. Read Less

Gender:

ALL

Ages:

12 years and above

Trial Updated:

06/17/2025

Locations: Cahaba Dermatology & Skin Health Center /ID# 263795, Birmingham, Alabama +232 locations

Cahaba Dermatology & Skin Health Center /ID# 263795, Birmingham, Alabama

Medical Dermatology Specialists /ID# 263394, Phoenix, Arizona

Dermatology Trial Associates /ID# 264587, Bryant, Arkansas

Arkansas Research Trials /ID# 263901, North Little Rock, Arkansas

Private Practice - Dr. Tooraj Raoof /ID# 263756, Encino, California

Dermatology Research Associates - Los Angeles /ID# 263765, Los Angeles, California

Stanford University School of Medicine - Redwood City /ID# 263711, Redwood City, California

Integrative Skin Science and Research /ID# 264600, Sacramento, California

Clinical Trials Research Institute /ID# 263743, Thousand Oaks, California

Clearlyderm Dermatology - West Boca /ID# 265023, Boca Raton, Florida

Apex Clinical Trials /ID# 263815, Brandon, Florida

TrueBlue Clinical Research /ID# 265041, Brandon, Florida

Skin Care Research - Hollywood /ID# 263805, Hollywood, Florida

GSI Clinical Research, LLC /ID# 263827, Margate, Florida

Sullivan Dermatology /ID# 263511, Miami, Florida

Renstar Medical Research - Ocala - Northeast 1st Avenue /ID# 263842, Ocala, Florida

Skin Care Research - Tampa /ID# 263819, Tampa, Florida

Advanced Clinical Research Institute /ID# 263808, Tampa, Florida

University of South Florida /ID# 269624, Tampa, Florida

Alliance Clinical Research of Tampa /ID# 264594, Tampa, Florida

Centricity Research Columbus Dermatology /ID# 266530, Columbus, Georgia

Cleaver Medical Group Dermatology /ID# 263845, Dawsonville, Georgia

Treasure Valley Medical Research /ID# 263671, Boise, Idaho

Northwestern University Feinberg School of Medicine /ID# 265007, Chicago, Illinois

Arlington Dermatology /ID# 263410, Rolling Meadows, Illinois

Dawes Fretzin, LLC /ID# 264601, Indianapolis, Indiana

Dermatology Partners of Leawood /ID# 263533, Leawood, Kansas

Equity Medical, LLC /ID# 268590, Bowling Green, Kentucky

Dermatology Specialists Research (DS Research) - Kentucky /ID# 263343, Louisville, Kentucky

Tulane University School of Medicine /ID# 263899, New Orleans, Louisiana

Beth Israel Deaconess Medical Center /ID# 263709, Boston, Massachusetts

Hamzavi Dermatology - Canton /ID# 263538, Canton, Michigan

Michigan Center for Medical Research /ID# 263547, Clarkston, Michigan

Dermatology and Skin Center of Lees Summit /ID# 263567, Lee's Summit, Missouri

MediSearch Clinical Trials /ID# 263582, Saint Joseph, Missouri

Vivida Dermatology- Flamingo /ID# 263716, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center - Old Etna Road /ID# 263713, Lebanon, New Hampshire

ActivMed Practice and Research, LLC /ID# 263387, Portsmouth, New Hampshire

Mount Sinai Doctors - Dermatology /ID# 264602, New York, New York

Atrium Health Wake Forest Baptist Medical Center /ID# 264507, Winston-Salem, North Carolina

Dermatology of Greater Columbus /ID# 263497, Bexley, Ohio

University Hospitals Cleveland Medical Center /ID# 263600, Cleveland, Ohio

Ohio State Officenter Gahanna /ID# 263598, Gahanna, Ohio

Dermatologists of Southwest Ohio - Mason /ID# 263588, Mason, Ohio

Apex Clinical Research Center /ID# 272787, Mayfield Heights, Ohio

Dermatology Partners /ID# 264999, Philadelphia, Pennsylvania

University of Pittsburgh Medical Center /ID# 264590, Pittsburgh, Pennsylvania

Clinical Research Center of the Carolinas /ID# 263407, Charleston, South Carolina

Medical University of South Carolina /ID# 263890, Charleston, South Carolina

ADCS - Spartanburg /ID# 267207, Spartanburg, South Carolina

Arlington Research Center, Inc /ID# 263895, Arlington, Texas

Bellaire Dermatology Associates /ID# 263850, Bellaire, Texas

Studies in Dermatology LLC /ID# 263399, Cypress, Texas

Reveal Research Institute, Dallas /ID# 267233, Dallas, Texas

Center for Clinical Studies - Houston - Binz Street /ID# 263378, Houston, Texas

Texas Dermatology Research Center /ID# 264488, Plano, Texas

Texas Dermatology and Laser Specialists /ID# 263778, San Antonio, Texas

Dermatology Associates of Tyler /ID# 265002, Tyler, Texas

University of Utah /ID# 263818, Murray, Utah

Virginia Clinical Research /ID# 264553, Norfolk, Virginia

Dermatology Specialists of Spokane /ID# 264499, Spokane, Washington

Paratus Clinical Research Woden /ID# 263125, Phillip, Australian Capital Territory

Momentum Clinical Research /ID# 263192, Darlinghurst, New South Wales

Premier Dermatology /ID# 263124, Kogarah, New South Wales

Veracity Clinical Research /ID# 263126, Woolloongabba, Queensland

Sinclair Dermatology - Melbourne /ID# 263121, East Melbourne, Victoria

Medizinische Universitaet Graz /ID# 263306, Graz, Steiermark

Medizinische Universitaet Wien /ID# 264043, Wien, Not set

Universite Libre de Bruxelles - Hopital Erasme /ID# 263097, Anderlecht, Bruxelles-Capitale

Cliniques Universitaires UCL Saint-Luc /ID# 263096, Bruxelles, Bruxelles-Capitale

Universitair Ziekenhuis Brussel /ID# 263101, Jette, Bruxelles-Capitale

Grand Hôpital de Charleroi - Les Viviers /ID# 263100, Charleroi, Hainaut

CHU de Liège /ID# 263095, Liège, Liege

UZ Gent /ID# 263099, Gent, Oost-Vlaanderen

Universitair Ziekenhuis Leuven /ID# 263098, Leuven, Vlaams-Brabant

Klinicki centar Banja Luka /ID# 265905, Banja Luka, Republika Srpska

Klinicki centar Banja Luka /ID# 265909, Banja Luka, Republika Srpska

Clinical Center University of Sarajevo - Bolnička /ID# 265908, Sarajevo, Not set

Acibadem City Clinic Tokuda Hospital /ID# 263300, Sofiya, Sofia

ASMC-IPSMC-Skin and Venereal Diseases /ID# 262891, Sofiya, Sofia

Medical Center Hera EOOD /ID# 263010, Sofiya, Sofia

Medical Center Cordis /ID# 262894, Pleven, Not set

Diagnostic consultative center Focus-5 /ID# 262893, Sofiya, Not set

UMHAT Professor Stoyan Kirkovich /ID# 262892, Stara Zagora, Not set

Beacon Dermatology Inc /ID# 264262, Calgary, Alberta

Rejuvenation Dermatology - Edmonton Downtown /ID# 265963, Edmonton, Alberta

Stratica Dermatology /ID# 265856, Edmonton, Alberta

Interior Dermatology Centre - Probity - PPDS /ID# 266202, Kelowna, British Columbia

Brunswick Dermatology Center /ID# 264260, Fredericton, New Brunswick

Karma Clinical Trials /ID# 265962, St. John's, Newfoundland and Labrador

Skin Health /ID# 267735, Cobourg, Ontario

Leader Research /ID# 266114, Hamilton, Ontario

DermEffects /ID# 265262, London, Ontario

Derm Care Clinic /ID# 265261, Mississauga, Ontario

York Dermatology Clinic & Research Centre /ID# 265265, Richmond Hill, Ontario

FACET Dermatology /ID# 265267, Toronto, Ontario

Private Practice - Dr. Kim Papp Clinical Research /ID# 265266, Waterloo, Ontario

Centre de Recherche Saint-Louis /ID# 265855, Québec, Quebec

Private Practice - Dr. Angelique Gagne-Henley /ID# 264263, St-Jérôme, Quebec

SkinSense Dermatology /ID# 265964, Saskatoon, Saskatchewan

Diex Recherche Quebec Inc. /ID# 265263, Quebec, Not set

Klinicki bolnicki centar Osijek /ID# 265916, Osijek, Osjecko-baranjska Zupanija

Klinicki Bolnicki Centar Zagreb /ID# 263989, Grad Zagreb, Not set

Specialty hospital Medico /ID# 263922, Rijeka, Not set

Fakultní nemocnice Ostrava /ID# 264041, Ostrava, Ostrava-mesto

Karlovarska Krajska Nemocnice - Karlovy Vary /ID# 265354, Karlovy Vary, Not set

Herlev and Gentofte Hospital /ID# 265839, Hellerup, Hovedstaden

Aarhus Universitetshospital - Skejby /ID# 265657, Aarhus, Midtjylland

Hopital Edouard Herriot /ID# 263456, Lyon, Auvergne-Rhone-Alpes

Centre Hospitalier Universitaire de Saint Etienne - Hopital Nord /ID# 263459, St-Priest-en-Jarez, Loire

Cabinet medical - Le bateau Blanc /ID# 263465, Martigues, Provence-Alpes-Cote-d Azur

Centre Hospitalier Universitaire de Rouen (CHU)- Hopital Charles Nicolle /ID# 263995, Rouen, Seine-Maritime

Groupe Hospitalier Paris Saint-Joseph /ID# 263996, Paris, Not set

Polyclinique Courlancy /ID# 263313, Reims, Not set

Universitaetsklinikum Freiburg /ID# 263659, Freiburg, Baden-Wuerttemberg

Universitaetsklinikum Tuebingen /ID# 271718, Tübingen, Baden-Wuerttemberg

Universitaetsklinikum Erlangen /ID# 263075, Erlangen, Bayern

Beldio Research GmbH /ID# 263074, Memmingen, Bayern

Rosenpark Research /ID# 269202, Darmstadt, Hessen

Fachklinik Bad Bentheim /ID# 263067, Bad Bentheim, Niedersachsen

Katholisches Klinikum Bochum /ID# 262976, Bochum, Nordrhein-Westfalen

Universitaetsklinikum Muenster /ID# 263068, Muenster, Nordrhein-Westfalen

Hautarztpraxis Mortazawi /ID# 271673, Remscheid, Nordrhein-Westfalen

Hautarztpraxis Dr. Kirschner /ID# 263656, Mainz, Rheinland-Pfalz

Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 263076, Berlin, Not set

University General Hospital Attikon /ID# 263413, Athens, Attiki

General Hospital Andreas Syggros /ID# 263417, Athens, Attiki

Hospital of Skin and Venereal Diseases- Thessaloniki /ID# 263416, Thessaloniki, Not set

Papageorgiou General Hospital /ID# 263415, Thessaloniki, Not set

Dermos S.A. /ID# 265857, Guatemala City, Not set

Prosalud /Id# 266586, Guatemala, Not set

Debreceni Egyetem-Klinikai Kozpont /ID# 263423, Debrecen, Hajdu-Bihar

Somogy Varmegyei Kaposi Mor Oktato Korhaz /ID# 263424, Kaposvár, Somogy

Semmelweis Egyetem /ID# 263451, Budapest, Not set

Pécsi Tudományegyetem /ID# 264120, Pécs, Not set

Our Lady of Lourdes Hospital - Drogheda /ID# 265893, Drogheda, Louth

South Infirmary Victoria University Hospital /ID# 265872, Cork, Not set

University College Dublin /ID# 265875, Dublin, Not set

Mater Misericordiae University Hospital /ID# 265914, Dublin, Not set

HaEmek Medical Center /ID# 267297, Afula, H_efa

Rambam Health Care Campus /ID# 262994, Haifa, H_efa

Rabin Medical Center /ID# 262992, Petah Tikva, HaMerkaz

Galilee Medical Center /ID# 262995, Naharia, HaTsafon

The Chaim Sheba Medical Center /ID# 262993, Ramat Gan, Tel-Aviv

Tel Aviv Sourasky Medical Center /ID# 266581, Tel Aviv, Tel-Aviv

Hadassah Medical Center-Hebrew University /ID# 262884, Jerusalem, Not set

AZIENDA USL TOSCANA CENTRO - Ospedale Piero Palagi /ID# 263454, Florence, Firenze

IRCCS Istituto Clinico Humanitas /ID# 263503, Rozzano, Lombardia

Azienda Ospedaliera Universitaria Federico II /ID# 263539, Naples, Napoli

Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 263473, Rome, Roma

AOU Policlinico G. Rodolico - San Marco /ID# 263469, Catania, Not set

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico /ID# 263471, Milano, Not set

Nagoya City University Hospital /ID# 263874, Nagoya, Aichi

Fujita Health University Hospital /ID# 265440, Toyoake, Aichi

Takagi Dermatological Clinic /ID# 264810, Obihiro-Shi, Hokkaido

Iwate Medical University Uchimaru Medical Center /ID# 273799, Morioka, Iwate

University Hospital Kyoto Prefectural University of Medicine /ID# 264291, Kyoto-shi, Kyoto

University of the Ryukyus Hospital /ID# 264605, Ginowan-shi, Okinawa

Kindai University Hospital /ID# 264322, Osaka sayama-shi, Osaka

Osaka Metropolitan University Hospital /ID# 265682, Osaka-shi, Osaka

Dokkyo Medical University Saitama Medical Center /ID# 265400, Koshigaya, Saitama

Fukuoka University Hospital /ID# 263991, Fukuoka, Not set

Nihon University Itabashi Hospital /ID# 264661, Tokyo, Not set

Pusan National University Hospital /ID# 271496, Busan, Busan Gwang Yeogsi

SoonChunHyang University Hospital Cheonan /ID# 271320, Cheonan-si, Chungcheongnamdo

Korea University Ansan Hospital /ID# 264227, Ansan-si, Gyeonggido

CHA Bundang Medical Center /ID# 264225, Seongnam, Gyeonggido

Yonsei University Health System Severance Hospital /ID# 271353, Seoul, Seoul Teugbyeolsi

SoonChunHyang University Seoul Hospital /ID# 264224, Seoul, Seoul Teugbyeolsi

Asan Medical Center /ID# 264228, Seoul, Seoul Teugbyeolsi

Hallym University Kangnam Sacred Heart Hospital /ID# 264226, Seoul, Seoul Teugbyeolsi

Eukarya PharmaSite /ID# 265307, Monterrey, Nuevo Leon

Sociedad de Metabolismo y Corazon S.C. /ID# 265915, Veracruz, Not set

Erasmus Medisch Centrum /ID# 263377, Rotterdam, Zuid-Holland

Clinical Trials New Zealand /ID# 265432, Hamilton, Waikato

Greenlane Clinical Centre /ID# 263191, Auckland, Not set

Stavanger Universitetssykehus /ID# 265997, Stavanger, Rogaland

Universitetssykehuset I Nord-Norge /ID# 265992, Tromsø, Troms

Oslo University Hospital - Rikshospitalet /ID# 265996, Oslo, Not set

Oftalmika sp. z o.o. /ID# 263087, Bydgoszcz, Kujawsko-pomorskie

DERMED Centrum Medyczne Sp. z o.o /ID# 263147, Lodz, Lodzkie

Santa Sp. z o..o. Santa Familia PTG Lodz /ID# 263181, Lodz, Lodzkie

Centrum Nowoczesnych Terapii 'Dobry Lekarz' sp.z.o.o. /ID# 263146, Krakow, Malopolskie

Klinika Ambroziak Dermatologia /ID# 263173, Warszawa, Mazowieckie

Unidade Local de Saude do Alto Ave, EPE /ID# 265158, Guimaraes, Braga

CUF Descobertas Hospital /ID# 263188, Lisbon, Lisboa

Unidade Local de Saude de Sao Jose, EPE /ID# 265155, Lisboa, Not set

Unidade Local de Saude de Santo Antonio, E.P.E. /ID# 265479, Porto, Not set

Private Practice - Dr. Alma Cruz /ID# 263204, Carolina, Not set

Clinical Research Puerto Rico /ID# 263450, San Juan, Not set

Spitalul Clinic Colentina /ID# 263303, Bucharest, Bucuresti

Private Practice - Dr. Orasan Remus /ID# 263305, Cluj Napoca, Cluj

Centrul Medical Euromed /ID# 263304, Bucharest, Not set

King Abdulaziz Medical City /ID# 266121, Jeddah, Makkah

King Saud University Med City /ID# 266120, Riyadh, Not set

Military Medical Academy /ID# 263257, Belgrade, Beograd

University Clinical Center Serbia /ID# 263256, Belgrade, Beograd

University Clinical Center Kragujevac /ID# 264211, Kragujevac, Sumadijski Okrug

University Clinical Center Vojvodina /ID# 263260, Novi Sad, Not set

National University Hospital /ID# 264673, Singapore, Not set

National Skin Centre /ID# 264680, Singapore, Not set

Univerzitna nemocnica L. Pasteura Kosice /ID# 263907, Košice, Kosicky Kraj

Fakultna nemocnica s poliklinikou Nove Zamky /ID# 265944, Nové Zámky, Nitriansky Kraj

Poliklinika Bezrucova (Cliniq s.r.o.) /ID# 263921, Bratislava, Not set

Fakultna nemocnica Trnava /ID# 263905, Trnava, Not set

University Medical Centre Ljubljana /ID# 265720, Ljubljana, Not set

University Medical Centre Maribor /ID# 265827, Maribor, Not set

Global Clinical Trials /ID# 262839, Pretoria, Gauteng

Life Chatsmed Garden Hospital /ID# 270237, Chatsworth, Kwazulu-Natal

Ahmed Al-Kadi Private Hospital /ID# 262837, Durban, Kwazulu-Natal

Dr Ahmed Ismail Manjra /ID# 262838, Westville, Kwazulu-Natal

Hospital Universitari Parc Tauli /ID# 262942, Sabadell, Barcelona

Hospital Universitario Marqués de Valdecilla /ID# 263039, Santander, Cantabria

Hospital Universitario Virgen de la Victoria /ID# 262941, Málaga, Malaga

Hospital de Manises /ID# 262938, Manises, Valencia

Hospital General Universitario Gregorio Marañón /ID# 262940, Madrid, Not set

Consorci Hospital General Universitario de Valencia /ID# 262944, Valencia, Not set

Karolinska University Hospital Solna /ID# 264530, Solna, Stockholms Lan

Universitetssjukhuset Örebro /ID# 265064, Örebro, Not set

Dermatology & Skin Care Clinic /ID# 264030, Buochs, Nidwalden

Kantonsspital St.Gallen /ID# 264238, St. Gallen, Sankt Gallen

University Hospital Zurich /ID# 266142, Zurich, Zuerich

Kaohsiung Chang Gung Memorial Hospital /ID# 264619, Kaohsiung City, Kaohsiung

National Taiwan University Hospital /ID# 264618, Taipei City, Taipei

Taichung Veterans General Hospital /ID# 270741, Taichung, Not set

Mackay Memorial Hospital /ID# 263661, Taipei City, Not set

Taipei Veterans General Hospital /ID# 265879, Taipei City, Not set

Linkou Chang Gung Memorial Hospital /ID# 264620, Taoyuan City, Not set

Queen Margaret Hospital /ID# 264198, Dunfermline, Fife

Gloucestershire Royal Hospital /ID# 265848, Gloucester, Gloucestershire

Disc_Barts Health NHS Trust - The Royal London Hospital /ID# 264121, London, Greater London

Harrogate District Hospital /ID# 265632, Harrogate, North Yorkshire

Bristol Royal Infirmary /ID# 263937, Bristol, Not set

Conditions: Hidradenitis Suppurativa

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A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

NCT06661915

Recruiting

This phase II trial compares the effect of ASTX727 in combination with iadademstat to ASTX727 alone in treating patients with accelerated or blast phase Philadelphia chromosome negative myeloproliferative neoplasms (MPNs). ASTX727 is a combination of two drugs, cedazuridine and decitabine. Cedazuridine is in a class of medications called cytidine deaminase inhibitors. It prevents the breakdown of decitabine, making it more available in the body so that decitabine will have a greater effect. Deci... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: City of Hope Comprehensive Cancer Center LAO, Duarte, California +4 locations

Conditions: Accelerated Phase Myeloproliferative Neoplasm, Blast Phase Myeloproliferative Neoplasm, Essential Thrombocythemia, Myelodysplastic/Myeloproliferative Neoplasm, Myeloproliferative Neoplasm, Not Otherwise Specified, Polycythemia Vera, Primary Myelofibrosis, Secondary Myelofibrosis

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A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

NCT06749457

Recruiting

The purpose of this study is to evaluate the safety and pharmacokinetics (PK) of AZD7760 when given as an intravenous infusion to healthy participants (Phase I) or participants with end-stage kidney disease receiving hemodialysis through a central venous catheter (Phase IIa).

Gender:

ALL

Ages:

Between 18 years and 55 years

Trial Updated:

06/17/2025

Locations: Research Site, Glendale, California +22 locations

Conditions: Staphylococcus Aureus

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Study of the Esophageal String Test (EST) for the Diagnosis of Helicobacter Pylori

NCT06871579

Recruiting

Background: Helicobacter pylori is a bacterium that infects the lining of the stomach and intestines. It can cause peptic ulcers, cancers, and infections. Current methods of diagnosing H. pylori infections have limitations. Researchers want to test a new method of testing for H. pylori. Objective: To compare the esophageal string test (EST) to standard tests for detecting H. pylori infection. Eligibility: People aged 18 years or older with persistent H. pylori infection. Design: Participa... Read More

Gender:

ALL

Ages:

Between 18 years and 99 years

Trial Updated:

06/17/2025

Locations: National Institutes of Health Clinical Center, Bethesda, Maryland

Conditions: Helicobacter Pylori

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A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

NCT07003425

Recruiting

This is a multicenter, double-blind, Long-Term Extension (LTE) study to evaluate the long-term safety and efficacy of APG777 in patients with moderate-to-severe AD who have completed treatment in an APG777 Parent Study (NCT06395948). The LTE study will consist of 3 periods: 1) Screening Visit will coincide with the last visit of the Maintenance Period in the Parent Study 2) Extended Treatment Period 3) Post-treatment Follow-up Period. This study will be conducted in participants with atopic de... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: Investigational Site #25, Fountain Valley, California +31 locations

Investigational Site #25, Fountain Valley, California

Investigational Site #1, Coral Gables, Florida

Investigational Site #22, Margate, Florida

Investigational Site #28, Detroit, Michigan

Investigational Site #4, Troy, Michigan

Investigational Site #29, Wilmington, North Carolina

Investigational Site #32, Boardman, Ohio

Investigational Site #27, Mason, Ohio

Investigational Site #31, Portland, Oregon

Investigational Site #23, Nashville, Tennessee

Investigational Site #30, Frisco, Texas

Investigational Site #26, San Antonio, Texas

Investigational Site #6, Calgary, Alberta

Investigational Site #10, Edmonton, Alberta

Investigational Site #7, Fredericton, Brunswick

Investigational Site #3, Markham, Ontario

Investigational Site #5, Mississauga, Ontario

Investigational Site #24, Peterborough, Ontario

Investigational Site #11, Toronto, Ontario

Investigational Site #12, Toronto, Ontario

Investigational Site #9, Toronto, Ontario

Investigational Site #2, Montréal, Quebec

Investigational Site #8, Quebec City, Quebec

Investigational Site #14, Wrocław, Dolnoslaskie

Investigational Site #19, Wrocław, Dolnośląskie

Investigational Site #15, Lublin, Lubelskie

Investigational Site #18, Warszawa, Mazowieckie

Investigational Site #17, Gdańsk, Pomorskie

Investigational Site #13, Katowice, Silesia

Investigational Site #16, Sosnowiec, Silesia

Investigational Site #20, Kraków, Woj. Małopolskie

Investigational Site #21, Łódź, Not set

Conditions: Atopic Dermatitis

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Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

NCT04079179

Recruiting

This is a research study of a drug called cobimetinib in children and adults diagnosed with Langerhans cell histiocytosis (LCH), and other histiocytic disorders that has returned or does not respond to treatment. Cobimetinib blocks activation of a protein called Mitogen-activated protein kinase (MEK) that is part of incorrect growth signals in histiocytosis cells. Four different groups of patients will be enrolled.

Gender:

ALL

Ages:

All

Trial Updated:

06/17/2025

Locations: Phoenix Children's Hospital, Phoenix, Arizona +11 locations

Conditions: Langerhan's Cell Histiocytosis, Juvenile Xanthogranuloma, Erdheim-Chester Disease, Rosai Dorfman Disease, Neuro-Degenerative Disease, Histiocytic Sarcoma, Histiocytic Disorders, Malignant

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A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine

NCT04965675

Recruiting

To find out if eptinezumab is better than placebo (normal saline solution) in lowering the number of days with migraine in young people ages 12 to 17 with chronic migraine.

Gender:

ALL

Ages:

Between 12 years and 17 years

Trial Updated:

06/17/2025

Locations: Yale-New Haven Children's Hospital, New Haven, Connecticut +74 locations

Yale-New Haven Children's Hospital, New Haven, Connecticut

Ki Health Partners LLC DBA New England Institute for Clinical Research, Stamford, Connecticut

Children's National Medical Center, Washington, District of Columbia

NW FL Clinical Research Group, LLC, Gulf Breeze, Florida

A G A Clinical Trials - HyperCore - PPDS, Hialeah, Florida

Axcess Medical Research, Loxahatchee Groves, Florida

University of South Florida, Tampa, Florida

University of Kentucky HealthCare (UKHC) Kentucky Clinic, Lexington, Kentucky

University of Maryland, Baltimore, Maryland

Michigan Head Pain and Neurological Institute, Ann Arbor, Michigan

Michigan State University - Department of Neurology, East Lansing, Michigan

Corewell Health Butterworth Hospital, Grand Rapids, Michigan

Dent Neurosciences Research Center Incorporated, Amherst, New York

North Suffolk Neurology-Commack, Commack, New York

OnSite Clinical Solutions, LLC - Randolph Rd - Charlotte - ClinEdge - PPDS, Charlotte, North Carolina

Cincinnati Children's Hospital Medical Center - PIN, Cincinnati, Ohio

The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Road Runner Research Ltd, San Antonio, Texas

Children's Specialty Group, Norfolk, Virginia

Mary Bridge Children's Hospital, Tacoma, Washington

Marshall University Medical Center, Huntington, West Virginia

Hospital Privado de La Comunidad, Mar Del Plata, Buenos Aires

Clínica Privada Independencia, Munro, Buenos Aires

Hospital Italiano de Buenos Aires, Ciudad Autónoma Buenos Aires, Ciudad Autónoma De BuenosAires

Expertia S.A- Mautalén Salud e Investigación, Ciudad Autónoma de Buenos Aires, Ciudad Autónoma De BuenosAires

Hospital Britanico de Buenos Aires, Ciudad Autónoma de Buenos Aires, Ciudad Autónoma De BuenosAires

Sanatorio Allende S.A, Ciudad De Cordoba, Córdoba

Hospital de Niños de La Santisima Trinidad, Córdoba-Barrio Crisol, Córdoba

Instituto Médico Río Cuarto, Río Cuarto, Córdoba

INECO Neurociencias Oroño, Rosario, Santa Fe

Centro de Investigaciones Médicas Tucumán - PPDS, San Miguel de Tucuman, Tucumán

University of Alberta, Edmonton, Alberta

Medical Arts Health Research Group - Penticton, Penticton, British Columbia

Vancouver Island Health Authority, Victoria, British Columbia

The Kids Clinic, Ajax, Ontario

London Health Sciences Centre -800 Commissioners Rd E, London, Ontario

Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Lazio

IRCCS Istituto Giannina Gaslini, Genova, Liguria

Ospedale San Raffaele S.r.l. - INCIPIT - PIN, Milano, Lombardia

Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Lombardia

Fondazione Istituto Neurologico Nazionale Casimiro Mondino IRCCS, Pavia, Lombardia

Azienda Ospedaliero Universitaria Consorziale Policlinico, Bari, Puglia

AO Brotzu - Clinica di Neuropsichiatria dell'Infanzia e dell'Adolescenza - INCIPIT - PIN, Cagliari, Sardegna

Azienda Ospedaliero Universitaria A Meyer - INCIPIT - PIN, Firenze, Toscana

Centro de Investigacion Medico Biologica y de Terapia Avanzada S.C., Guadalajara, Jalisco

Unidad de Investigación en Salud de Chihuahua S.C., Zapopan, Jalisco

Centro de Investigacion Clinica Chapultepec S.A. de C.V. - Morelia, Morelia, Michoacán

ICARO Investigaciones en Medicina, S.A de C.V, Chihuahua, Not set

Neurociencias Estudios Clinicos S.C., Culiacán Sinaloa, Not set

Instituto de Investigationes Clinicas para la Salud A.C., Durango, Not set

Unidad de Investigación en Salud de Chihuahua S.C.-Mexico city, Mexico City, Not set

Clinical Research Institute SC-Mexico, Tepetlacalco, Not set

Centro de Estudios Clinicos Y Especialidades Medicas SC, Vista Hermosa, Not set

ULS de Almada-Seixal, EPE - Hospital Garcia de Orta, Almada, Setúbal

ULS de Coimbra, EPE - Hospital Pediátrico de Coimbra, Coimbra, Not set

ULS de São João, EPE - Hospital de São João, Porto, Not set

Childrens University Hospital, Belgrade, Not set

University Clinical Center Kragujevac, Kragujevac, Not set

Children and Youth Health Care Institute of Vojvodina, Novi Sad, Not set

Clinical Centre of Vojvodina, Novi Sad, Not set

CHUVI - H.U. Alvaro Cunqueiro, Vigo, Pontevedra

Hospital Universitario Vall d'Hebron - PPDS, Barcelona, Not set

Instituto del Sueño, Madrid, Not set

Hospital Clinico San Carlos, Madrid, Not set

Hospital Universitario Virgen del Rocio - PPDS, Sevilla, Not set

Hospital Universitari i Politecnic La Fe de Valencia, Valencia, Not set

Izmir City Hospital, Bayraklı, Izmir

Eskisehir Osmangazi Universitesi Tip Fakultesi Hastanesi, Eskisehir, Not set

Istanbul University Cerrahpasa Medical Faculty Hospital, Fatih/Istanbul, Not set

Mersin University Medical Faculty, Mersin, Not set

Royal Devon and Exeter Hospital NHS Trust, Exeter, Devon

Queen Elizabeth University Hospital - PPDS, Glasgow, Lanarkshire

Great Ormond Street Hospital, London, London, City Of

Royal Hospital for Children and Young People - PIN, Edinburgh, Midlothian

James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, Norfolk

Conditions: Chronic Migraine in Children

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