Depending on the type of Eczema, its exact cause of is not yet known. However, atopic dermatitis is believed to be related to malfunction of the body’s immune system. Like asthma and hay fever, atopic dermatitis may ultimately be caused by an immune system overreaction that creates an allergic response to common irritants. Futher clinical research into the cause of Eczema are ongoing.
What is Eczema?
czema, also known as atopic dermatitis, is an itchy inflammation of the upper layers of skin. It is very common, affecting up to 35 million Americans with more than 3 million new cases per year. It presents a red, scaly, itchy rash that is easily mistaken for other skin conditions.
Symptoms are usually most noticeable on the arms and behind the knees. However, eczema can appear anywhere throughout the body. The cracked, rough skin affected by the condition can sometimes develop painful blisters.
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What Causes Eczema?
What are the Different Types of Eczema?
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Atopic Dermatitis
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Contact Dermatitis
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Dyshidrotic Eczema
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Neurodermatitis
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Nummular Eczema
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Seborrheic Dermatitis
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Stasis Dermatitis
How is Eczema Diagnosed?
About 10% to 20% of infants and 3% of children and adults in the United States have eczema. Overall, about 10% of people have some form of eczema. At any age, the majority of people who present symptoms of eczema have had the condition since very early in life.
Most infants will outgrow the condition, but not all.
To diagnose eczema, a doctor will look at family history. Families with an existing history of eczema, allergies, asthma, or defects in the skin barrier are more likely to see cases of eczema. No lab tests are needed, but a skin patch test is used to rule out other conditions.
How is Eczema Treated or Cured?
The majority of eczema patients will experience periodic flare-ups of the condition. Between these flare-ups, the condition may be asymptomatic – that is, patients will not experience any discomfort. Eczema is not contagious, so these periods are uneventful. With Eczema being a condition affecting a large number of individuals, a wide array of clinical trials are ongoing.
During eczema flare-ups, a doctor may recommend many types of treatment to reduce symptoms. The most common is medicated cream that reduces the itching and repairs damage to affected skin. Over time, patients learn which medication is best for them.
Eczema can be compounded by a bacterial infection from the open cracks or sores in the skin. In this case, antibacterial medication must be used to fight infection. In severe flare-ups, oral corticosteroids are recommended to reduce the body’s inflammation response.
An appropriate course of proactive treatment significantly reduces the complications and the discomfort associated with eczema. Although new treatments have shown promise, there is no cure for the condition.
Eczema Clinical Trials
The following clinical trial are the most up to date provided by Clinicaltrials.gov. If you would like us to feature some additional trials, please feel free to notify our team.
ClinicalTrials.gov: Recruiting Studies | eczema | Last update posted in the last 300 days Studies found on ClinicalTrials.gov by a search of: Recruiting Studies | eczema | Last update posted in the last 300 days
- Atopic Dermatitis: Sub-Saharan Africa vs. Central Europeon May 6, 2022 at 4:00 pm
Condition: Atopic DermatitisIntervention: Other: ObservationSponsors: University of Zurich; Regional Dermatology Training Centre (RDTC), MoshiRecruiting
- Study on the Influence of Climatic and Environmental Factors on Respiratory Diseases in Sanya, Hainan Province, China.on April 15, 2022 at 4:00 pm
Conditions: Asthma; Allergic Rhinitis; Chronic Obstructive Pulmonary Disease(COPD); Atopic Dermatitis; Eczema; Urticaria; Bronchitis; Bronchiectasis Adult; EmphysemaIntervention: Other: Climate and environment in SanyaSponsor: Shanghai Jiao Tong University School of MedicineRecruiting
- Phase III Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Atopic Dermatitison April 13, 2022 at 4:00 pm
Condition: Atopic DermatitisInterventions: Drug: Benvitimod Cream; Drug: PlaceboSponsors: Peking University People's Hospital; Zhonghao PharmaceuticalRecruiting
- Tacrolimus Versus Hydrocortisone in Atopic Dermatitison April 12, 2022 at 4:00 pm
Conditions: Atopic; DermatitisInterventions: Drug: Tacrolimus; Drug: HydrocortisoneSponsors: Ain Shams University; National Hepatology & Tropical Medicine Research InstituteRecruiting
- China Type II Inflammatory Skin Disease Clinical Research and Standardized Diagnosis and Treatment Projecton April 7, 2022 at 4:00 pm
Conditions: Atopic Dermatitis Eczema; Prurigo NodularisIntervention: Sponsor: Peking University First HospitalRecruiting
- A Single-ascending Dose (Part A) and Repeat-dose (Part B) Study to Investigate the Safety, Pharmacokinetics and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)on March 14, 2022 at 4:00 pm
Condition: Atopic DermatitisInterventions: Biological: UCB1381; Drug: PlaceboSponsor: UCB Biopharma SRLRecruiting
- Dupilmuab for Atopic Dermatitis Monitored With Noninvasive Imaging.on March 3, 2022 at 5:00 pm
Conditions: Eczema; Atopic DermatitisInterventions: Drug: Dupilumab; Device: Optical Coherence Tomography; Device: Reflectance confocal microscopySponsors: OptiSkin Medical; Regeneron PharmaceuticalsRecruiting
- Study the Safety and Efficacy of DBI-001 Gel Versus Aqueous Gelon February 24, 2022 at 5:00 pm
Condition: Atopic DermatitisInterventions: Biological: DBI-001; Biological: Aqueous gelSponsors: DermBiont, Inc.; Derm Research, PLLC; North Sound DermatologyRecruiting
- Topical Ruxolitinib Evaluation in Chronic Hand Eczema Study 2on February 10, 2022 at 5:00 pm
Condition: Chronic Hand Eczema (CHE)Interventions: Drug: Ruxolitinib cream; Drug: VehicleSponsor: Incyte CorporationRecruiting
- Immunomodulation by OM-85 (Broncho-Vaxom) in Early ADon February 3, 2022 at 5:00 pm
Condition: Atopic DermatitisInterventions: Drug: Broncho-Vaxom; Drug: PlaceboSponsor: OM PharmaRecruiting
- Topical Ruxolitinib Evaluation in Chronic Hand Eczema Study 1on February 2, 2022 at 5:00 pm
Condition: Hand EczemaInterventions: Drug: Ruxolitinib cream; Drug: VehicleSponsor: Incyte CorporationRecruiting
- SAD/MAD Safety and PK Study of RBN-3143 in Healthy and Atopic Dermatitis Subjectson January 31, 2022 at 5:00 pm
Condition: Atopic DermatitisIntervention: Drug: RBN-3143Sponsor: Ribon Therapeutics, Inc.Recruiting
Patients coping with a new eczema diagnosis or long-term eczema symptoms may be able to reduce flare-ups by learning about what worsens their condition. As with conventional allergies, many different environmental stressors can trigger a flare-up.
After a diagnosis, it is a good idea to keep a symptom journal. Patients should list out symptoms, when and where they occurred, and if there were any factors that might have contributed. Over time, it can become much easier to notice and avoid eczema triggers.
Food is among the most common eczema trigger. Some people experience heavy symptoms after exposure to nuts or dairy. It isn’t necessary to consume these foods to have symptoms: Just touching them can be enough. Dietary triggers should be eliminated entirely.
Certain soaps, detergents, and shampoos are common triggers. Patients should be especially careful about commercial antibacterial hand soap. Since bacteria can also exacerbate symptoms, it is important to find bathroom soaps that do not contribute to symptoms.
Eczema may be sensitive to extreme humidity or hot or cold temperatures. This causes eczema in some people to have a seasonal cycle. No matter the time of year, stress can make symptoms worse.
Match to Eczema Clinical Trials
- Access to cutting-edge treatments
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- Find trials in your area
- https://www.webmd.com/skin-problems-and-treatments/guide/
- https://www.mayoclinic.org/diseases-conditions/atopic-dermatitis-eczema/diagnosis-treatment/drc-20353279topic-dermatitis-eczema
- https://www.medicalnewstoday.com/articles/14417.php
- https://nationaleczema.org/research/eczema-facts/
- https://www.contactdermatitisinstitute.com/