There are currently 1011 clinical trials in Birmingham, Alabama looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Alabama at Birmingham, University of Alabama, University of Alabama at Birmingham Cancer Center and University of Alabama Birmingham. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Study to Evaluate Participant Satisfaction and Natural Outcomes Following Administration of BOTOX Cosmetic Injections in Adult Participants for Treatment of Upper Facial Lines
NCT06218251
Recruiting
Facial lines that develop from repeated facial expression, such as glabellar lines (GL), lateral canthal lines (LCL), and forehead lines (FHL), are typically treated by selectively weakening specific muscles with small quantities of botulinum toxin. The purpose of this study is to evaluate participant satisfaction and natural outcomes following the administration of BOTOX Cosmetic in adult participants with upper facial lines (GL, LCL, and FHL). This is an open-label study in which all particip... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: Skin Wellness Dermatology - Homewood /ID# 248469, Birmingham, Alabama
Conditions: Upper Facial Lines
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Sponsor-Initiated OCS Liver Perfusion (OLP-II) Registry
NCT05940857
Recruiting
OLP-II Registry is a sponsor-initiated, multi-center, observational, post-approval registry.
Gender:
All
Ages:
All
Trial Updated:
04/10/2024
Locations: University of Alabama, Birmingham, Alabama
Conditions: Liver Transplant
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Gut Microbe Composition, Exercise, and Breast Breast Cancer Survivors
NCT04088708
Recruiting
The primary goal of this project is to determine the effects of exercise on the gut microbiome in breast cancer survivors and determine how these changes may relate to psychosocial symptoms such as fatigue.
Gender:
Female
Ages:
Between 18 years and 74 years
Trial Updated:
04/10/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Breast Cancer, Gut Microbiome, Exercise, Fatigue
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Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
NCT03007147
Recruiting
This randomized phase III trial studies how well imatinib mesylate works in combination with two different chemotherapy regimens in treating patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukemia (ALL). Imatinib mesylate has been shown to improve outcomes in children and adolescents with Philadelphia chromosome positive (Ph+) ALL when given with strong chemotherapy, but the combination has many side effects. This trial is testing whether a different chemother... Read More
Gender:
All
Ages:
Between 1 year and 21 years
Trial Updated:
04/10/2024
Locations: Children's Hospital of Alabama, Birmingham, Alabama
Conditions: Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia, T Acute Lymphoblastic Leukemia
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Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
NCT00736749
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
All
Ages:
All
Trial Updated:
04/10/2024
Locations: Children's Hospital of Alabama, Birmingham, Alabama +1 locations
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
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MicroRNA Correlates of Childhood Maltreatment and Suicidality
NCT04923685
Recruiting
This is a research study to find out if childhood trauma and stress are associated with depression or suicidal risk. The study will assess the effects of both short-term and long-term stress on biomarker (e.g. miRNA [MiRNA]) levels. miRNAs are a type of RNA (genetic material that is translated into protein) that are found in throughout the body and blood. They are called microRNA because their size is much smaller than typical RNA molecules. miRNAs are highly responsive to environment. This resp... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
04/10/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Major Depressive Disorder, Suicidal Ideation
Register for Updates
A Phase 1b / 2 Drug Resistant Immunotherapy With Activated, Gene Modified Allogeneic or Autologous γδ T Cells (DeltEx) in Combination With Maintenance Temozolomide in Subjects With Recurrent or Newly Diagnosed Glioblastoma
NCT05664243
Recruiting
This multicenter, Phase 1b/2 study is being conducted to determine if the experimental cell therapy is safe, tolerable and can delay the return of cancer in patients with a newly diagnosed or recurrent glioblastoma multiforme (GBM) in combination with standard chemotherapy treatment temozolomide (TMZ). If there is a 25% or greater improvement in survival in this study then the therapy should be studied further.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Glioblastoma
Register for Updates
The Impact of a Virtual Magic Trick Training Program
NCT05664841
Recruiting
The proposed project will attempt to confirm the benefits of a structured magic trick training program (MTTP) experience in adolescents with autism. Benefits of participating in a 6-week virtual MTTP will be evaluated using validated assessments to measure social-emotional competencies.
Gender:
All
Ages:
Between 12 years and 18 years
Trial Updated:
04/09/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Autism, Pervasive Developmental Disorder
Register for Updates
Maternal Newborn Health Registry
NCT01073475
Recruiting
The primary purpose of this population-based study is to quantify and understand the trends in pregnancy outcomes in defined low-resource geographic areas over time, in order to provide population-based data on stillbirths, neonatal and maternal mortality.
Gender:
All
Ages:
All
Trial Updated:
04/09/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Pregnancy Outcome Trends in Low-resource Geographic Areas
Register for Updates
Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry
NCT01915511
Recruiting
This registry will collect data on the strategies used to achieve a diagnosis of Idiopathic Pulmonary Fibrosis (IPF) and Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype (ILD) and the treatment and management efforts applied throughout study follow-up, clinical outcome events and patient reported outcome data. Blood samples will be collected periodically throughout the study for use in future research efforts. For participants with non-IPF, chronic fibrosing ILD with progre... Read More
Gender:
All
Ages:
30 years and above
Trial Updated:
04/09/2024
Locations: University of Alabama - Birmingham, Birmingham, Alabama
Conditions: Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease
Register for Updates
Feasibility Trial of a Stakeholder-enhanced Lay-navigator-delivered Intervention (ImPart-Multi)
NCT06067009
Recruiting
We seek to explore the feasibility and acceptability of participation in a decision-support training program led by lay navigators. ImPart-Multi, an education-telehealth-based, is designed to empower Black chronic kidney disease patients (CKD) patients and their care partner to seek the resources and support needed to be activated allies when making health-related decisions. Participants, based on random assignment, will participate in survey completion at study start and at 12 and 24 weeks of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/08/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Kidney Diseases, Cardiometabolic Risk Factors
Register for Updates
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
NCT05812807
Recruiting
The phase III trial compares the effect of pembrolizumab to observation for the treatment of patients with early-stage triple-negative breast cancer who achieved a pathologic complete response after preoperative chemotherapy in combination with pembrolizumab. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial may help researchers determine if observa... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/08/2024
Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama
Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Early Stage Triple-Negative Breast Carcinoma
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