There are currently 1026 clinical trials in Birmingham, Alabama looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Alabama at Birmingham, University of Alabama, University of Alabama at Birmingham Cancer Center and University of Alabama Birmingham. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Ten-Week Online Acceptance and Commitment Therapy Intervention for Family Caregivers of People With Dementia
Recruiting
This randomized controlled trial aims to assess the effects of a coach-guided ten-week videoconferencing acceptance and commitment therapy (ACT) program on mental health outcomes in depressed family caregivers of people with dementia (PwD) compared to the control group. A total of 64 family caregivers of PwD who meet the eligibility criteria will be recruited and randomized to either the intervention group or the control group. The hypotheses are that the ACT group will show improvements in depr... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/14/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Depressive Symptoms
Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults
Recruiting
Mobility refers to a person's purposeful movement through the environment from one place to another and can be conceptualized as a continuum from bed bound (immobility) on one extreme to making excursions to distant locations on the other extreme. Primary open-angle glaucoma (POAG) is a chronic, progressive optic neuropathy that can lead to gradual loss of vision in the peripheral field and central vision. Older adults with POAG have an increased risk for motor vehicle collisions and falls. More... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/14/2023
Locations: University of Alabama Birmingham, Birmingham, Alabama
Conditions: Primary Open Angle Glaucoma
Histiocytic Disorder Follow-up Study
Recruiting
The purpose of the study is to describe the burden of chronic health conditions, psychological dysfunction, chronic pain, healthcare utilization, worse health-related quality of life, overall mortality, and cause-specific mortality among individuals with histiocytic disorders
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
06/13/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Histiocytosis, Langerhans Cell Histiocytosis, Erdheim-Chester Disease, Rosai Dorfman Disease, Xanthogranuloma, Malignant Histiocytoses
The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive)
Recruiting
The ProActive registry is a longitudinal, multi-center study with a prospective arm observing clinical care for patients receiving physician ordered Prospera, an allograft rejection test, and a historical control arm collecting data on cases at the same sites whose kidney allograft rejection status was managed with Serum Creatinine SCr/estimated Glomerular Filtration Rate eGFR. This registry will compare patient management and outcomes in patients who receive Prospera (Prospera arm) to the outco... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Kidney Transplant Rejection
Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study
Recruiting
Prospective, multicenter, randomized, open-label study of standard of care plus the PMX cartridge versus standard of care alone in patients with endotoxemic septic shock
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Septic Shock, Endotoxemia
B Cell and Antibody Response to Seasonal Influenza Vaccines in Younger and Older Adults
Recruiting
This study will examine how various FDA-approved seasonal influenza vaccine types, used in a manner consistent with their approved use, impact the characteristics of influenza specific antibodies in humans, and how these responses differ based on age and prior immunization history.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/07/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Influenza
The Impact of Insomnia on Pain in HIV
Recruiting
The overall objective of this application is to investigate the impact of insomnia on pain, physical functioning, and inflammation in people living with HIV. The two aims of this study to determine 1) whether insomnia promotes increased sensitivity and inflammatory reactivity to pain stimuli, and 2) if weekly fluctuations in insomnia burden drive changes in inflammation, pain severity, and physical functioning in people living with HIV. This research could help confirm insomnia as a therapeutic... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/01/2023
Locations: UAB, Birmingham, Alabama
Conditions: HIV, Insomnia
Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis
Recruiting
The purpose of the study is to describe Hemophagocytic lymphohistiocytosis (HLH) in patients with lymphoma to identify possible therapeutic strategies to improve overall survival of the patients with lymphoma associated hemophagocytic lymphohistiocytosis.
Gender:
All
Ages:
All
Trial Updated:
06/01/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Lymphoma, Hemophagocytic Lymphohistiocytoses
Renal Metabolism of Glycolate to Oxalate
Recruiting
This study will determine the contribution of glycolate metabolism to urinary oxalate excretion in healthy subjects, using carbon 13 isotope glycolate tracer technique and a low-oxalate controlled diet.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/26/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Healthy
International CIPN Assessment and Validation Study
Recruiting
This is an observational study of chemotherapy-induced peripheral neurotoxicity (CIPN) patients to be investigated prospectively in order to assess responsiveness of a set of outcome measures in an international multi-center study.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2023
Locations: Birmingham School of Nursing, University of Alabama, Birmingham, Alabama
Conditions: Chemotherapy-induced Peripheral Neuropathy, Quality of Life
Evaluating the Implementation and Impact of Navigator-delivered ePRO System
Recruiting
1) Evaluate implementation of navigator-delivered Home ePRO for all cancer patients across multiple practice sites; 2) examine the barriers, facilitators, and implementation strategies used in implementing navigator-delivered Home ePRO; and 3) assess the impact of Home ePRO on clinical and utilization outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama +1 locations
Conditions: Cancer
DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
Recruiting
DECAMP 1 PLUS aims to improve the efficiency of the diagnostic evaluation of patients with indeterminate pulmonary nodules (8-25 mm). Molecular biomarkers for lung cancer diagnosis measured in minimally invasive and non-invasive biospecimens may be able to distinguish between malignant or benign indeterminate pulmonary nodules in high-risk smokers. Ultimately, this study aims to validate molecular as well as clinical and imaging biomarkers of lung cancer in individuals with indeterminate lung no... Read More
Gender:
All
Ages:
46 years and above
Trial Updated:
05/16/2023
Locations: University of Alabama, Birmingham, Birmingham, Alabama
Conditions: Pulmonary Disease