There are currently 1011 clinical trials in Birmingham, Alabama looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Alabama at Birmingham, University of Alabama, University of Alabama at Birmingham Cancer Center and University of Alabama Birmingham. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Automated Imaging Differentiation of Parkinsonism
Recruiting
The purpose of this study is to test the performance of the AID-P across 21 sites in the Parkinson Study Group. Each site will perform imaging, clinical scales, diagnosis, and will upload the data to the web-based software tool. The clinical diagnosis will be blinded to the diagnostic algorithm and the imaging diagnosis will be compared to the movement disorders trained neurologist diagnosis.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
11/13/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Parkinson Disease, Multiple System Atrophy, Parkinson Variant, Progressive Supranuclear Palsy
The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy.
Recruiting
The Achieve Trial is a randomized clinical trial to test whether lowering blood pressure to less than 140/90 mmHg in women with hypertensive disorders of pregnancy will prolong pregnancy.
Gender:
Female
Ages:
Between 14 years and 49 years
Trial Updated:
11/12/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Preeclampsia, Gestational Hypertension, Hypertensive Disorder of Pregnancy
Clinical Trial of Multi-Periscopic Prism Glasses for Hemianopia
Recruiting
This clinical trial will evaluate the efficacy of two types of high-power prism glasses that provide field of view expansion for patients with homonymous hemianopia (the complete loss of half the field of vision on the same side in both eyes).
Gender:
All
Ages:
7 years and above
Trial Updated:
11/09/2023
Locations: UAB Center for Low Vision Rehabilitation, Callahan Eye Hospital, Birmingham, Alabama
Conditions: Homonymous Hemianopia
Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)
Recruiting
The purpose of this study is to characterize the developmental phenotype of ASD and ID and to identify biomarkers using advanced MRI methodology and electrophysiological biomarkers of synaptic function and connectivity predictive of ASD and ID presence and severity in patients with TSC. In addition, this study will be establishing infrastructure for the collection and storage of human bio-specimens, including genetic material, from TSC patients and their family members with ASD.
Gender:
All
Ages:
18 months and above
Trial Updated:
11/09/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Tuberous Sclerosis, Autism Disorder, Intellectual Disability
Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women
Recruiting
SMARTT will estimate the incidence of conditions and diagnoses potentially related to in utero exposure to antiretroviral therapy and/or exposure in the first two months of life among children born of HIV-infected mothers.
Gender:
All
Ages:
All
Trial Updated:
11/09/2023
Locations: University of Alabama, Birmingham, Alabama
Conditions: Antiretroviral Toxicity
Rapid HCV Treatment Access for Persons Who Use Drugs
Recruiting
This study is being done to compare two strategies to deliver HCV treatment to persons with hepatitis C virus (HCV) who also use drugs and are participating in an outpatient opioid treatment program (OTP). Participants will be randomized into one of two treatment groups: Test and treat plus peer-mentors: This treatment group will be offered 8 weeks of glecaprevir/pibrentasvir (an FDA approved HCV treatment) within days of HCV diagnosis at the OTP. Participants in this group will receive treatme... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
11/08/2023
Locations: University of Alabama, Birmingham, Alabama
Conditions: Hepatitis C Virus Infection, Response to Therapy of
Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation
Recruiting
This study aims to enroll 58 pre-adolescent (<13 years) pediatric participants with sickle cell disease (SCD) who have a pre-adolescent sibling bone marrow donor. All participants will go through a pre-transplant evaluation to find out if there are health problems that will keep them from being able to receive the transplant. It usually takes 2 to 3 months to complete the pre-transplant evaluation and make the arrangements for the transplant. Once they are found to be eligible for transplant, pa... Read More
Gender:
All
Ages:
Between 2 years and 13 years
Trial Updated:
11/07/2023
Locations: Children's Hospital of Alabama, Birmingham, Alabama
Conditions: Sickle Cell Disease
Yogic Breathing Exercise for People With Amyotrophic Lateral Sclerosis
Recruiting
The aim of this study is to understand how well a 6-week virtual yogic breathing exercise program (YBEP) will improve breathing, speech, and emotional well-being in people with amyotrophic lateral sclerosis (ALS).
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
11/07/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Amyotrophic Lateral Sclerosis
Follow-up Visit of High Risk Infants
Recruiting
The NICHD Neonatal Research Network's Follow-Up study is a multi-center cohort in which surviving extremely low birth-weight infants born in participating network centers receive neurodevelopmental, neurosensory and functional assessments at 22-26 months corrected age (Infants born prior to July 1, 2012 were seen at 18-22 months corrected age). Data regarding pregnancy and neonatal outcome are collected prospectively. The goal is to identify potential maternal and neonatal risk factors that may... Read More
Gender:
All
Ages:
Between 18 months and 26 months
Trial Updated:
11/07/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Generic Database of Very Low Birth Weight Infants
Recruiting
The Generic Database (GDB) is a registry of very low birth weight infants born alive in NICHD Neonatal Research Network (NRN) centers. The GDB collects observational baseline data on both mothers and infants, and the therapies used and outcomes of the infants. The information collected is not specific to a disease or treatment (i.e., it is "generic"). Data are analyzed to find associations and trends between baseline information, treatments, and infant outcome, and to develop future NRN trials.
Gender:
All
Ages:
14 days and below
Trial Updated:
11/07/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV
Recruiting
People aging with HIV are at higher risk for Alzheimer's disease and related dementias, and although physical activity is a promising target to mitigate such risk, this population engages in low levels of physical activity. Few studies have tested cognitive effects of exercise interventions or examined mechanisms of adherence to long-term exercise among diverse samples of midlife and older people with HIV. The current study will leverage an existing R01 to address these gaps and provide implicat... Read More
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
11/07/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: HIV Infections, Cognitive Impairment
Chronic Widespread Pain in HIV: Novel Mechanisms and Therapeutics
Recruiting
To determine if decreased production or release of endogenous opioid peptides by peripheral immune cells contributes to hypersensitivity in people with HIV
Gender:
All
Ages:
Between 19 years and 65 years
Trial Updated:
11/06/2023
Locations: Clinical Research Unit at the University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Chronic Widespread Pain