There are currently 1011 clinical trials in Birmingham, Alabama looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Alabama at Birmingham, University of Alabama, University of Alabama at Birmingham Cancer Center and University of Alabama Birmingham. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Herbal Nutraceutical Supplementation on Vasomotor Symptoms in Menopausal Women
NCT05813067
Recruiting
The role of nutrition is recognized as a vital component to healthy aging throughout menopause. The goal of this study is to evaluate a dietary supplement for its safety and effects on vasomotor symptoms in menopausal women.
Gender:
Female
Ages:
Between 40 years and 65 years
Trial Updated:
07/28/2023
Locations: Alabama Clinical Therapeutics, Birmingham, Alabama
Conditions: Vasomotor Symptoms, Postmenopausal Disorders
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Valved Graft PMCF Study
NCT04754217
Recruiting
Multicenter, global, prospective, non-randomized, interventional, post-market trial. All subjects enrolled will receive an Abbott Valved Graft device.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/28/2023
Locations: University Hospital - Univ. of Alabama at Birmingham (UAB), Birmingham, Alabama
Conditions: Aortic Valve Disease, Ascending Aorta Abnormality, Aortic Dissection
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HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia
NCT04131413
Recruiting
The primary goal of this phase I open label study is to determine the safety and tolerability of pNGVL4aCRTE6E7L2 DNA vaccine, as administered by intramuscular (IM) injection with TriGrid™ electroporation to both HIV- or HIV+ adult female subjects (≥ 19 years), with biopsy confirmed cervical intraepithelial (CIN) II or III that is human papillomavirus (HPV) 16+.
Gender:
Female
Ages:
19 years and above
Trial Updated:
07/27/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Human Papillomavirus Type 16, Cervical Intraepithelial Neoplasia Grade II, Cervical Intraepithelial Neoplasia, Grade III
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Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection
NCT05219110
Recruiting
The objective of this study is to determine if early high volume intravenous fluid administration (hyperhydration) may be effective in mitigating or preventing complications of shiga toxin-producing E. coli (STEC) infection in children and adolescents when compared with traditional approaches (conservative fluid management).
Gender:
All
Ages:
Between 9 months and 21 years
Trial Updated:
07/21/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection, Hemolytic-Uremic Syndrome
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Providing an Optimized and emPowered Pregnancy for You (PᵌOPPY) Feasibility Study
NCT05940688
Recruiting
The P3OPPY Project is one of five projects within the American Heart Association P3 EQUATE Network. The overarching goal of the P3 EQUATE American Heart Association Health Equity Research Network (HERN) is to promote equity in Maternal and Infant Health outcomes by identifying innovative and cost-effective strategies to enhance access to quality health information, care, and experiences during pregnancy, postnatal and postpartum/preconception periods, particularly for Black and under-served popu... Read More
Gender:
Female
Ages:
Between 16 years and 49 years
Trial Updated:
07/19/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Pregnancy, Infants, Disparities
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The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis
NCT04372615
Recruiting
Determine the difference in the modified Rankin score at 16 weeks in participants with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis treated with "first-line" immunomodulatory therapies provided as standard-of-care, and either inebilizumab (investigational agent) or placebo.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/19/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Autoimmune Encephalitis, Encephalitis
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Low-GI Diet vs High-GI Diet in Individuals With SCI
NCT05334342
Recruiting
The purpose of this pilot research project is to examine the impact of a low-glycemic index (GI) diet on postprandial hypotension and glucose control in individuals with chronic spinal cord injury. The objectives are: 1) To evaluate the effect of the low-GI diet on the magnitude of postprandial systolic blood pressure drop compared to a high-GI control diet. 2)To evaluate the effect of a low-GI diet on postprandial glucose and insulin responses compared to a high-GI control diet.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
07/18/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Spinal Cord Injuries, Postprandial Hypotension, Glucose Metabolism Disorders
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Non-Invasive Monitoring of Traumatic Brain Injury Progression Using the Infrascanner (MOBI-1)
NCT04893837
Recruiting
MOBI-1 is a multicenter clinical trial that will evaluate the use of the Infrascanner for the monitoring of traumatic intracranial hematomas.
Gender:
All
Ages:
15 years and above
Trial Updated:
07/11/2023
Locations: UAB Hospital, Birmingham, Alabama
Conditions: Brain Injuries, Traumatic
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Prehabilitation Feasibility Among Older Adults Undergoing Transplantation
NCT05642884
Recruiting
This is a pilot feasibility trial among older adults (≥60y) scheduled to undergo Autologous Stem Cell transplantation at UAB. Participants will be randomized into either a prehabilitation program or an attention control group before their transplant. The primary outcomes will be feasibility and secondary outcomes include changes in physical function at the time of transplant and at 12 weeks follow up.
Gender:
All
Ages:
60 years and above
Trial Updated:
07/11/2023
Locations: Kirklin Clinic of UAB Hospital, Birmingham, Alabama
Conditions: Multiple Myeloma
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Predicton of Sepsis Recovery Performance Subtypes Pilot Study
NCT05912413
Recruiting
This study addresses critically ill sepsis patients' current literature reports of ongoing post-hospital discharge weakness and hospital readmissions. This study is aimed at capture and interpretation of a complex set of tests, administered during a subject's sepsis functional recovery trajectory, particularly capturing hospital readmission's effects on survivors' physical function recovery.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/11/2023
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama
Conditions: Sepsis
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Simple Bone Cysts in Kids
NCT02193841
Recruiting
Simple bone cysts (SBCs) are cysts filled with fluid that occur most frequently in the long bones (arms or legs) of children. There are many ways to treat SBCs but it is unclear if one is better than another. The purpose of this research trial is to compare the effectiveness of two common treatments that are used by surgeons today.
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
07/10/2023
Locations: Children's Hospital of Alabama, Birmingham, Alabama
Conditions: Bone Cyst
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UAB Alzheimer's Disease Center Core Cohort - Tau Imaging Substudy
NCT03809351
Recruiting
The primary objective of this study is to measure the concentration and the regional brain distribution of pathologic tau deposition using the PET tracer AV-1451 in participants in the UAB-ADC cohort. The amount and distribution of AV-1451 in the brain will be correlated to demographic, clinical, genetic, and biospecimen data acquired through the separate ongoing UAB-ADC study. Assessment of interactions between race and vascular risk factors, brain tau levels measured with AV-1451-PET, and cogn... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
07/06/2023
Locations: UAB, Birmingham, Alabama
Conditions: Alzheimer Disease
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