Cyclophosphamide Treatment Options in Canada

A collection of 300 research studies where Cyclophosphamide is the interventional treatment. These studies are located in the Canada . Cyclophosphamide is used for conditions such as Breast Cancer, Lymphoma and Leukemia.

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Fludarabine and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Lymphocytic Leukemia or Waldenstrom's Macroglobulinemia

NCT00281983

Completed

RATIONALE: Giving chemotherapy before a donor bone marrow transplant helps stop the growth of cancer cells. It also helps stop the patient's immune system from rejecting the donor's stem cells. Also, monoclonal antibodies, such as alemtuzumab, can find cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. When the healthy stem cells from a donor are infused into the patient they may help the patient's bone marrow make stem cells, red blood c... Read More

Gender:

ALL

Ages:

Between 18 years and 65 years

Trial Updated:

07/20/2017

Locations: Maisonneuve-Rosemont Hospital, Montreal, Quebec +12 locations

Conditions: Chronic Lymphocytic Leukemia

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FCR Versus FC Alone in the Treatment of Chronic Lymphocytic Leukemia (CLL) in Relapsed Patients

NCT00090051

Completed

The purpose of this study is to provide treatment for patients who have chronic lymphocytic leukemia (CLL), and to compare the use of rituximab added to fludarabine+cyclophosphamide (FC) with FC alone, to determine if rituximab lengthens the time a patient remains free of leukemia symptoms.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/05/2017

Locations: Uab Comprehensive Cancer Center, Birmingham, Alabama +105 locations

Uab Comprehensive Cancer Center, Birmingham, Alabama

Pacific Coast Hematology/Oncology Medical Group, Fountain Valley, California

California Cancer Center Woodward Park; Community Medical Centers, Fresno, California

Rush-Presbyterian St. Luke'S Medical Center, Chicago, Illinois

Duke University Medical Center, Durham, North Carolina

Milton S. Hershey Medical Center; Penn State Cancer Inst., Hershey, Pennsylvania

Concord Repatriation General Hospital; Haematology, Sydney, New South Wales

Mater Hospital; Division of Cancer Services, Brisbane, Queensland

Frankston Hospital; Oncology/Haematology, Frankston, Victoria

Peter Maccallum Cancer Institute; Medical Oncology, Melbourne, Victoria

ZNA Stuivenberg, Antwerpen, Not set

Institut Jules Bordet, Bruxelles, Not set

UZ Leuven Gasthuisberg, Leuven, Not set

Uni of Alberta Hospital, Edmonton, Alberta

BCCA-Vancouver Cancer Centre, Vancouver, British Columbia

Health Science Centre, St. John's, Newfoundland and Labrador

QEII HSC; Oncology, Halifax, Nova Scotia

Hamilton Health Sciences - Juravinski Cancer Centre; Hematology, Hamilton, Ontario

The Ottawa Regional Hospital - General Campus; Division of Hematology, Box 704, Ottawa, Ontario

Sunnybrook Odette Cancer Centre, Toronto, Ontario

University Health Network; Princess Margaret Hospital; Medical Oncology Dept, Toronto, Ontario

Mcgill University - Royal Victoria Hospital; Oncology, Montreal, Quebec

Righospitalet, Hæmatologisk Klinik, København Ø, Not set

Aarhus Universitetshospital, Hæmatologisk Afdeling R, Århus, Not set

Hopital Avicenne; Hematologie Biologique, Bobigny, Not set

Hopital Clemenceau; Hematologie Clinique, Caen, Not set

Chu Estaing; Hematologie Clinique Adultes, Clermont Ferrand, Not set

Hopital Henri Mondor; Hematologie Clinique, Creteil, Not set

Clinique Victor Hugo; Chimiotherapie, Le Mans, Not set

Hopital Claude Huriez; Hematologie, Lille, Not set

Hopital Edouard Herriot; Bat.E-Hematologie, Lyon, Not set

Centre Leon Berard; Departement Oncologie Medicale, Lyon, Not set

Institut J Paolii Calmettes; Onco Hematologie 1, Marseille, Not set

Hôpital Lapeyronie; Hématologie Oncologie Médicale, Montpellier, Not set

Hopital Hotel Dieu Et Hme;Hopital De Jour, Nantes, Not set

Hotel Dieu; Hematologie- Oncologie, Paris, Not set

Inserm Cic 9504, Paris, Not set

Hopital Pitie Salpetriere; Hematologie Clinique, Paris, Not set

Ch Lyon Sud; Hemato Secteur Jules Courmont, Pierre Benite, Not set

Chu La Miletrie; Hdj Cons Hemato Cancerologie, Poitiers, Not set

Centre Henri Becquerel; Hematologie, Rouen, Not set

Hopital Bretonneau; Clinique D'Oncologie & de Radiotherapie, Tours, Not set

Hopitaux De Brabois; Hematologie Medecine Interne, Vandoeuvre Les Nancy, Not set

Szent Laszlo Hospital; Hematology Dept, Budapest, Not set

National Institute of Oncology, A Dept of Internal Medicine, Budapest, Not set

Országos Gyógyintézeti Központ; Haematologiai Osztaly, Budapest, Not set

Uni of Debrecen; 2Nd Clinic of Internal Medicine, Debrecen, Not set

University of Debrecen Medical and Health Science Center, Institute of Internal Medicine, Hematology, Debrecen, Not set

Uni of Pecs; Dept of Internal Medicine, Pecs, Not set

University of Szeged, II Dept of Internal Medicine, Szeged, Not set

A.O. Universitaria Federico II Di Napoli; Oncologia Ed Endocrinologia Clinica, Napoli, Campania

A.O. Universitaria Policlinico S.Orsola-Malpighi Di Bologna, Bologna, Emilia-Romagna

Ospedale S. Eugenio; Divisione Di Ematologia, Roma, Lazio

Az. Osp. S. Camillo Forlanini; Uo Ematologia E Trapianti Di Midollo Osseo, Roma, Lazio

Universita' Degli Studi La Sapienza-Ist.Di Ematologia;Dip. Biotecnologie Cel CELLULARI ED EMATOLOGIA, Roma, Lazio

Asst Grande Ospedale Metropolitano Niguarda; Dipartimento Di Ematologia Ed Oncologia, Milano, Lombardia

Irccs Policlinico San Matteo; Divisione Di Ematologia, Pavia, Lombardia

Uni Degli Studi Di Bari, Policlinico; Cattedra Di Ematologia,Dipart. Di Medicina Interna E Publica, Bari, Puglia

IRCCS Ospedale Casa Sollievo Della Sofferenza; Ematologia E Trapianto Di Midollo Osseo, San Giovanni Rotondo, Puglia

Ospedale Di Vicenza; Nefrologia, Ematologia, Vicenza, Veneto

Meander Mc, Locatie Lichtenberg; Dept of Lung Diseases, Amersfoort, Not set

Academisch Medisch Centrum Universiteit Amsterdam, Amsterdam, Not set

Leyenburg Ziekenhuis; Haematology, Den Haag, Not set

Erasmus Mc - Daniel Den Hoed Kliniek; Medical Oncology, Rotterdam, Not set

Auckland city hospital; Auckland Regional Cancer Centre and Blood Service, Auckland, Not set

Christchurch Hospital; Canterbury Health Laboratories, Christchurch, Not set

Wellington Hospital; Regional Oncology Unit, Wellington, Not set

Haukeland Universitetshospital; Medicine Dept, Bergen, Not set

Rikshospitalet Uni Hospital, Oslo, Not set

Medical University School; Dept. of Haematology, Lodz, Not set

Katedra i Klinika Hematoonkologii i Transplantacji Szpiku; Uniwersytetu Medycznego w Lublinie, Lublin, Not set

Akademii Medycznej W; Klinika Hematologii, Poznan, Not set

Klin. Chorob Wewnetrznych I Hemat. Z Osrodkiem Transplant. Szpiku, Warszawa, Not set

Instytut Hematologii I Transfuzjologii; Klinika Chorob Wewnetrznych I Hematologii, Warszawa, Not set

Samodzielny Publiczny Centralny Szpital Kliniczny; Haematology Dept., Warszawa, Not set

Fundeni Clinical Inst. ; Hematology Dept, Bucharest, Not set

Spitalul Clinic Coltea; Clinica de Hematologie, Bucuresti, Not set

Spitalul Clinic Judetean de Urgenta Targu-Mures; compartiment Hematologie, Targu-mures, Not set

Spitalul Clinic municipal de Urgenta Timisoara; Clinica de Hematologie, Timisoara, Not set

N.N.Blokhin Russian Cancer Research Center; Dept. of Chemotherapy & Hemoblastosis, Moscow, Not set

Haematology Research Center; Haematology, Moscow, Not set

City Clinical Botkin's Hospital; City Hematological Center, Moscow, Not set

Medical Radiological Research Centre Rams; Dept. of Radiotherapy & Chemotherapy of Hemoblastosis, Obninsk, Not set

Regional Clinical Hospital N.A. Kalinin; Hematology Dept, Samara, Not set

Research Inst. Hematology /Blood Transfusion ; Hemablastosis, Supression Hemopoesis & B M Transplant, St Petersburg, Not set

Regional Clinical Hospital; Hematology Dept. #2 For B M Transplantation & High Dose Chemo., St Petersburg, Not set

Pavlov State Medical Uni ; Bone Marrow Transplantation Clinic, St Petersburg, Not set

S.-Peterburg Pavlov State Medical University ; Haematology, St Petersburg, Not set

State Medical Inst. Municipal Hospital #31; Oncology & Hematology Dept. With the Usechemo. in Adult, St Petersburg, Not set

Hospital Universitario de la Princesa; Servicio de Hematologia, Madrid, Not set

Hospital Univ. 12 de Octubre; Servicio de Hematologia, Madrid, Not set

Hospital Clinico Universitario de Salamanca;Servicio de Hematologia, Salamanca, Not set

Hospital Clinico Universitario de Valencia; Servicio de Onco-hematologia, Valencia, Not set

Hospital Universitario Miguel Servet; Servicio Hematologia, Zaragoza, Not set

Karolinska Inst. , Huddinge Uni Hospital; Depart. of Hematology, Huddinge, Not set

Universitetssjukhuset i Linköping, Hematologkliniken, Linkoeping, Not set

Royal Bournemouth General Hospital; Haematology, Bournemouth, Not set

Addenbrookes Hospital; Haematology, Cambridge, Not set

Stobhill Hospital; Dept of Haematology, Glasgow, Not set

Leeds General Infirmary; Medicine, Leeds, Not set

Leicester Royal Infirmary; Dept of Haematology, Leicester, Not set

Royal Liverpool Uni Hospital; Haematology, Liverpool, Not set

St. Bartholomew'S Hospital; Dept of Medical Oncology, London, Not set

King'S College Hospital; Haematology, London, Not set

Royal Marsden Hospital; Academic Dept of Haematology, Sutton, Not set

Pinderfields General Hospital; Dept of Haematology, Wakefield, Not set

Conditions: Chronic Lymphocytic Leukemia

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Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors

NCT00335556

Completed

This phase II trial is studying how well combination chemotherapy, radiation therapy, and/or surgery work in treating patients with high-risk kidney tumors. Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving combination chemotherapy together with radiat... Read More

Gender:

ALL

Ages:

29 years and below

Trial Updated:

06/22/2017

Locations: Children's Hospital of Alabama, Birmingham, Alabama +186 locations

Children's Hospital of Alabama, Birmingham, Alabama

University of Alabama at Birmingham, Birmingham, Alabama

University of South Alabama, Mobile, Alabama

Phoenix Childrens Hospital, Phoenix, Arizona

University of Arizona Health Sciences Center, Tucson, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

Southern California Permanente Medical Group, Downey, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's Hospital, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Children's Hospital Central California, Madera, California

Children's Hospital and Research Center at Oakland, Oakland, California

Kaiser Permanente-Oakland, Oakland, California

Childrens Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

Rady Children's Hospital - San Diego, San Diego, California

University of California San Francisco Medical Center-Parnassus, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, D.C., District of Columbia

Lombardi Comprehensive Cancer Center at Georgetown University, Washington, D.C., District of Columbia

Broward Health Medical Center, Fort Lauderdale, Florida

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

Memorial Healthcare System - Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville South, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Miami Children's Hospital, Miami, Florida

Baptist Hospital of Miami, Miami, Florida

Florida Hospital Orlando, Orlando, Florida

UF Cancer Center at Orlando Health, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

All Children's Hospital, Saint Petersburg, Florida

Saint Joseph Children's Hospital of Tampa, Tampa, Florida

Saint Mary's Hospital, West Palm Beach, Florida

Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia

Memorial University Medical Center, Savannah, Georgia

University of Hawaii Cancer Center, Honolulu, Hawaii

Tripler Army Medical Center, Honolulu, Hawaii

Saint Luke's Mountain States Tumor Institute, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Advocate Lutheran General Hospital., Park Ridge, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University, Springfield, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Saint Vincent Hospital and Health Services, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa Hospitals and Clinics, Iowa City, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Kosair Children's Hospital, Louisville, Kentucky

Tulane University Health Sciences Center, New Orleans, Louisiana

Children's Hospital New Orleans, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Maine Children's Cancer Program, Scarborough, Maine

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

University of Massachusetts Medical School, Worcester, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Saint John Hospital and Medical Center, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Hurley Medical Center, Flint, Michigan

Helen DeVos Children's Hospital at Spectrum Health, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Kalamazoo Center for Medical Studies, Kalamazoo, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

Mayo Clinic, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

The Childrens Mercy Hospital, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Saint John's Mercy Medical Center, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Nevada Cancer Research Foundation CCOP, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Morristown Memorial Hospital, Morristown, New Jersey

UMDNJ - Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Overlook Hospital, Summit, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

University of New Mexico, Albuquerque, New Mexico

Roswell Park Cancer Institute, Buffalo, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

New York University Langone Medical Center, New York, New York

Columbia University Medical Center, New York, New York

Memorial Sloan-Kettering Cancer Center, New York, New York

Weill Medical College of Cornell University, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

Mission Hospital-Memorial Campus, Asheville, North Carolina

University of North Carolina, Chapel Hill, North Carolina

Carolinas Medical Center, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

East Carolina University, Greenville, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

The Toledo Hospital/Toledo Children's Hospital, Toledo, Ohio

Mercy Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Natalie Warren Bryant Cancer Center at Saint Francis, Tulsa, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Legacy Emanuel Hospital and Health Center, Portland, Oregon

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Penn State Hershey Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Palmetto Health Richland, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Greenville Cancer Treatment Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

St. Jude Children's Research Hospital, Memphis, Tennessee

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee

Texas Tech University Health Science Center-Amarillo, Amarillo, Texas

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont College of Medicine, Burlington, Vermont

Inova Fairfax Hospital, Falls Church, Virginia

Childrens Hospital-King's Daughters, Norfolk, Virginia

Naval Medical Center - Portsmouth, Portsmouth, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Carilion Clinic Children's Hospital, Roanoke, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

West Virginia University Charleston, Charleston, West Virginia

University of Wisconsin Hospital and Clinics, Madison, Wisconsin

Marshfield Clinic, Marshfield, Wisconsin

Midwest Children's Cancer Center, Milwaukee, Wisconsin

John Hunter Children's Hospital, Hunter Regional Mail Centre, New South Wales

Sydney Children's Hospital, Randwick, New South Wales

The Children's Hospital at Westmead, Westmead, New South Wales

Royal Brisbane and Women's Hospital, Herston, Queensland

Royal Children's Hospital-Brisbane, Herston, Queensland

Women's and Children's Hospital-Adelaide, North Adelaide, South Australia

Royal Children's Hospital, Parkville, Victoria

Princess Margaret Hospital for Children, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

University of Alberta Hospital, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Child Health Centre, Saint John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Chedoke-McMaster Hospitals, Hamilton, Ontario

Cancer Centre of Southeastern Ontario at Kingston General Hospital, Kingston, Ontario

Children's Hospital, London, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Centre Hospitalier Universitaire de Quebec, Ste-Foy, Quebec

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Starship Children's Hospital, Grafton, Auckland

San Jorge Children's Hospital, San Juan, Not set

Conditions: Childhood Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma, Clear Cell Sarcoma of the Kidney, Papillary Renal Cell Carcinoma, Rhabdoid Tumor of the Kidney, Stage I Renal Cell Cancer, Stage I Renal Wilms Tumor, Stage II Renal Cell Cancer, Stage II Renal Wilms Tumor, Stage III Renal Cell Cancer, Stage III Renal Wilms Tumor, Stage IV Renal Cell Cancer, Stage IV Renal Wilms Tumor

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Intergroup Randomized Trial for Children or Adolescents With B-Cell Non Hodgkin Lymphoma or B-Acute Leukemia: Rituximab Evaluation in High Risk Patients

NCT01516580

Unknown

The aim of the trial is to test whether adding 6 injections of rituximab to standard "Lymphome malin B" LMB chemotherapy regimen improves the Event Free Survival (EFS) compared with LMB chemotherapy alone in children / adolescents with advanced stage B-cell Non-Hodgkin Lymphoma (NHL) / B-Acute Leukemia (B-AL)(stage III and LDH \> Nx2, any stage IV or B-AL).

Gender:

ALL

Ages:

Between 6 months and 17 years

Trial Updated:

06/13/2017

Locations: University Hospitals Leuven, Leuven, Not set +9 locations

Conditions: B-cell Non Hodgkin Lymphoma, Mature B-cell Leukemia Burkitt-type

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Phase 1 Study of a Cancer Vaccine to Treat Patients With Advanced Stage Ovarian, Fallopian or Peritoneal Cancer

NCT01416038

Completed

Immunotherapy is a novel way to treat cancer and does so by targeting the immune system to destroy tumor cells. Many different therapeutic vaccines have been evaluated in phase 1, 2, and even phase 3 trials. Much has been learned about the principles of applying immune-based therapies and specifically the types of patients that may be most likely to mount an effective immune response. When used alone, cancer vaccines may have their greatest impact earlier in the disease course or in situations w... Read More

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

04/20/2017

Locations: Roswell Park Cancer Institute, Buffalo, New York +6 locations

Conditions: Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer

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Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma

NCT01222715

Completed

This randomized phase II trial studies how well vinorelbine tartrate and cyclophosphamide work in combination with bevacizumab or temsirolimus in treating patients with recurrent or refractory rhabdomyosarcoma. Drugs used in chemotherapy, such as vinorelbine tartrate and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Som... Read More

Gender:

ALL

Ages:

29 years and below

Trial Updated:

03/24/2017

Locations: Children's Hospital of Alabama, Birmingham, Alabama +183 locations

Children's Hospital of Alabama, Birmingham, Alabama

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

Phoenix Childrens Hospital, Phoenix, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Southern California Permanente Medical Group, Downey, California

City of Hope Comprehensive Cancer Center, Duarte, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars-Sinai Medical Center, Los Angeles, California

Children's Hospital Central California, Madera, California

Children's Hospital and Research Center at Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Rady Children's Hospital - San Diego, San Diego, California

UCSF Medical Center-Parnassus, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, District of Columbia

Lee Memorial Health System, Fort Myers, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Florida Hospital Orlando, Orlando, Florida

Nemours Children's Clinic - Orlando, Orlando, Florida

UF Cancer Center at Orlando Health, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

All Children's Hospital, Saint Petersburg, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Hospital, West Palm Beach, Florida

Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia

Memorial University Medical Center, Savannah, Georgia

University of Hawaii Cancer Center, Honolulu, Hawaii

Saint Luke's Mountain States Tumor Institute, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana

Riley Hospital for Children, Indianapolis, Indiana

Saint Vincent Hospital and Health Care Center, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Kosair Children's Hospital, Louisville, Kentucky

Tulane University Health Sciences Center, New Orleans, Louisiana

Children's Hospital New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Maine Children's Cancer Program, Scarborough, Maine

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Floating Hospital for Children at Tufts Medical Center, Boston, Massachusetts

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Dana-Farber/Harvard Cancer Center, Boston, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Saint John Hospital and Medical Center, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Helen DeVos Children's Hospital at Spectrum Health, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Kalamazoo Center for Medical Studies, Kalamazoo, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

University of Missouri - Ellis Fischel, Columbia, Missouri

The Childrens Mercy Hospital, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Nevada Cancer Research Foundation CCOP, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Saint Barnabas Medical Center, Livingston, New Jersey

Morristown Medical Center, Morristown, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Overlook Hospital, Summit, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

Winthrop University Hospital, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

Columbia University/Herbert Irving Cancer Center, New York, New York

Memorial Sloan-Kettering Cancer Center, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

Mission Hospital-Memorial Campus, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Medical Center-Fargo, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

The Toledo Hospital/Toledo Children's Hospital, Toledo, Ohio

Mercy Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Natalie Warren Bryant Cancer Center at Saint Francis, Tulsa, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Legacy Emanuel Hospital and Health Center, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Geisinger Medical Center, Danville, Pennsylvania

Penn State Hershey Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Medical University of South Carolina, Charleston, South Carolina

Palmetto Health Richland, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Greenville Cancer Treatment Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

St. Jude Children's Research Hospital, Memphis, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Texas Tech University Health Science Center-Amarillo, Amarillo, Texas

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

Brooke Army Medical Center, Fort Sam Houston, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

M D Anderson Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont College of Medicine, Burlington, Vermont

University of Virginia Cancer Center, Charlottesville, Virginia

Inova Fairfax Hospital, Falls Church, Virginia

Childrens Hospital-King's Daughters, Norfolk, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

West Virginia University Charleston, Charleston, West Virginia

Saint Vincent Hospital, Green Bay, Wisconsin

University of Wisconsin Hospital and Clinics, Madison, Wisconsin

Midwest Children's Cancer Center, Milwaukee, Wisconsin

Sydney Children's Hospital, Randwick, New South Wales

The Children's Hospital at Westmead, Westmead, New South Wales

Princess Margaret Hospital for Children, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

University of Alberta Hospital, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Child Health Centre, Saint John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Chedoke Hospital at Hamilton Health Sciences, Hamilton, Ontario

Cancer Centre of Southeastern Ontario at Kingston General Hospital, Kingston, Ontario

Children's Hospital, London, Ontario

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Allan Blair Cancer Centre, Regina, Saskatchewan

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Centre Hospitalier Universitaire de Quebec, Quebec, Not set

Starship Children's Hospital, Grafton, Auckland

Christchurch Hospital, Christchurch, Not set

Conditions: Adult Rhabdomyosarcoma, Childhood Alveolar Rhabdomyosarcoma, Childhood Pleomorphic Rhabdomyosarcoma, Childhood Rhabdomyosarcoma With Mixed Embryonal and Alveolar Features, Previously Treated Childhood Rhabdomyosarcoma, Recurrent Adult Soft Tissue Sarcoma, Recurrent Childhood Rhabdomyosarcoma

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Phase II ABT-888 With Cyclophosphamide

NCT01306032

Completed

Background: - The experimental cancer treatment drug ABT-888 (Veliparib) works by preventing deoxyribonucleic acid (DNA) repair in tumor cells. Cyclophosphamide is a cancer treatment drug that works by causing DNA damage in cells, including cancer cells, resulting in cell death. However, because cyclophosphamide has strong and unpleasant side effects, researchers are interested in finding drugs that can be given in combination with cyclophosphamide that will allow a lower dose of cyclophosphamide to be given with similar effects. The combination of ABT-88 and cyclophosphamide may be an effective treatment for some types of cancer, such as certain kinds of breast or ovarian cancer and non-Hodgkin's lymphoma that often do not respond to standard therapies. Objectives: - To evaluate the safety and effectiveness of ABT-888 and cyclophosphamide in ovarian and breast cancer and in non-Hodgkin's lymphoma that have not responded to standard treatments. Eligibility: - Individuals at least 18 years of age who have been diagnosed with (1) (Breast cancer 1/2) BRCA1/2 ovarian cancer, primary peritoneal or ovarian high-grade carcinoma, or fallopian tube cancer; (2) triple-negative breast cancer (not responsive to hormone-related therapy); or (3) low grade non-Hodgkin's lymphoma. Design: * Participants will be screened with a full medical history and physical examination, blood and urine tests, and tumor imaging studies. Participants will be divided into two groups with different treatment subgroups. * Group 1: Participants who have BRCA-positive ovarian cancer, primary peritoneal or ovarian high-grade serous carcinoma, or fallopian tube cancer * Participants will receive either the combination of ABT-888 and cyclophosphamide, or cyclophosphamide alone. * Participants will take the study drug by mouth once a day for 21-day cycles of treatment, and will keep a diary to record drug doses and any side effects. * Participants will have clinic visits with blood and urine tests, imaging studies, and other examinations on days 1, 2, 7, and 14 of cycle 1, and on the first day of all other cycles. * Group 2: Participants who have triple-negative breast cancer or non-Hodgkin's lymphoma * Participants will receive either the combination of ABT-888 and cyclophosphamide, or cyclophosphamide alone. * Participants will take the study drug by mouth once a day for 21-day cycles of treatment, and will keep a diary to record drug doses and any side effects. * Participants will have clinic visits with blood and urine tests, imaging studies, and other examinations on days 1, 2, 7, and 14 of cycle 1, and on the first day of all other cycles. * Participants receiving only cyclophosphamide who show signs of disease progression after tumor imaging studies can receive the combination of ABT-888 with cyclophosphamide. * Treatment will continue as long as participants tolerate the drugs and the disease does not progress. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/16/2017

Locations: University of California, Davis, Davis, California +9 locations

Conditions: Ovarian Cancer, Primary Peritoneal Cancer, Serous Carcinoma Cancer, Triple-Negative Breast Cancer, Fallopian Tube Cancer

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Chemotherapy With or Without Additional Chemotherapy and/or Radiation Therapy in Treating Children With Newly Diagnosed Hodgkin's Disease

NCT00025259

Completed

This randomized phase III trial is studying different chemotherapy regimens given with or without radiation therapy to compare how well they work in treating children with newly diagnosed Hodgkin's disease. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Giving the drugs in different combinations may kill more cancer cells. Radiation therapy uses high-energy x-rays to damage cancer cells. It is not yet known if chemotherapy is more ef... Read More

Gender:

ALL

Ages:

21 years and below

Trial Updated:

03/15/2017

Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +174 locations

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

Phoenix Childrens Hospital, Phoenix, Arizona

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Southern California Permanente Medical Group, Downey, California

City of Hope Comprehensive Cancer Center, Duarte, California

Loma Linda University Medical Center, Loma Linda, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars-Sinai Medical Center, Los Angeles, California

David Geffen School of Medicine at UCLA, Los Angeles, California

Children's Hospital Central California, Madera, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Rady Children's Hospital - San Diego, San Diego, California

Santa Barbara Cottage Hospital, Santa Barbara, California

Children's Hospital Colorado, Aurora, Colorado

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, District of Columbia

Broward Health Medical Center, Fort Lauderdale, Florida

Lee Memorial Health System, Fort Myers, Florida

University of Florida, Gainesville, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Nicklaus Children's Hospital, Miami, Florida

Baptist Hospital of Miami, Miami, Florida

Florida Hospital Orlando, Orlando, Florida

Nemours Children's Clinic - Orlando, Orlando, Florida

All Children's Hospital, Saint Petersburg, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Hospital, West Palm Beach, Florida

Georgia Regents University Medical Center, Augusta, Georgia

University of Hawaii Cancer Center, Honolulu, Hawaii

Saint Luke's Mountain States Tumor Institute, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Advocate Lutheran General Hospital, Park Ridge, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Kosair Children's Hospital, Louisville, Kentucky

Tulane University Health Sciences Center, New Orleans, Louisiana

Children's Hospital New Orleans, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Baystate Medical Center, Springfield, Massachusetts

University of Massachusetts Medical School, Worcester, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Saint John Hospital and Medical Center, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Hurley Medical Center, Flint, Michigan

Kalamazoo Center for Medical Studies, Kalamazoo, Michigan

William Beaumont Hospital-Royal Oak, Royal Oak, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

University of Missouri - Ellis Fischel, Columbia, Missouri

The Childrens Mercy Hospital, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

University of Nebraska Medical Center, Omaha, Nebraska

Nevada Cancer Research Foundation CCOP, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Overlook Hospital, Summit, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Brooklyn Hospital Center, Brooklyn, New York

Roswell Park Cancer Institute, Buffalo, New York

Winthrop University Hospital, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Mount Sinai Medical Center, New York, New York

Columbia University/Herbert Irving Cancer Center, New York, New York

Weill Medical College of Cornell University, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

Mission Hospital-Memorial Campus, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

East Carolina University, Greenville, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Medical Center-Fargo, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

The Toledo Hospital/Toledo Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Natalie Warren Bryant Cancer Center at Saint Francis, Tulsa, Oklahoma

Legacy Emanuel Hospital and Health Center, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Medical University of South Carolina, Charleston, South Carolina

Palmetto Health Richland, Columbia, South Carolina

Greenville Cancer Treatment Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Texas Tech University Health Science Center-Amarillo, Amarillo, Texas

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

M D Anderson Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont College of Medicine, Burlington, Vermont

University of Virginia Cancer Center, Charlottesville, Virginia

Inova Fairfax Hospital, Falls Church, Virginia

Childrens Hospital-King's Daughters, Norfolk, Virginia

Naval Medical Center - Portsmouth, Portsmouth, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Carilion Clinic Children's Hospital, Roanoke, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

West Virginia University Charleston, Charleston, West Virginia

Saint Vincent Hospital, Green Bay, Wisconsin

University of Wisconsin Hospital and Clinics, Madison, Wisconsin

Marshfield Clinic, Marshfield, Wisconsin

Midwest Children's Cancer Center, Milwaukee, Wisconsin

Royal Brisbane and Women's Hospital, Herston, Queensland

Women's and Children's Hospital-Adelaide, North Adelaide, South Australia

Princess Margaret Hospital for Children, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

University of Alberta Hospital, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Child Health Centre, Saint John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

Chedoke Hospital at Hamilton Health Sciences, Hamilton, Ontario

Cancer Centre of Southeastern Ontario at Kingston General Hospital, Kingston, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Allan Blair Cancer Centre, Regina, Saskatchewan

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Centre Hospitalier Universitaire de Quebec, Quebec, Not set

Schneider Children's Medical Center of Israel, Petah Tikua, Not set

Starship Children's Hospital, Grafton, Auckland

Christchurch Hospital, Christchurch, Not set

San Jorge Children's Hospital, San Juan, Not set

Swiss Pediatric Oncology Group - Geneva, Geneva, Not set

Conditions: Childhood Lymphocyte-Depleted Classical Hodgkin Lymphoma, Childhood Mixed Cellularity Classical Hodgkin Lymphoma, Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma, Childhood Nodular Sclerosis Classical Hodgkin Lymphoma, Stage I Childhood Hodgkin Lymphoma, Stage II Childhood Hodgkin Lymphoma, Stage III Childhood Hodgkin Lymphoma, Stage IV Childhood Hodgkin Lymphoma

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Surgery in Treating Children With Neuroblastoma

NCT00003119

Completed

RATIONALE: Surgery alone may be effective in treating children with neuroblastoma. PURPOSE: Phase III trial to study the effectiveness of surgery alone in treating children who have neuroblastoma.

Gender:

ALL

Ages:

21 years and below

Trial Updated:

03/09/2017

Locations: University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama +234 locations

University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama

University of South Alabama Cancer Research Institute, Mobile, Alabama

Phoenix Children's Hospital, Phoenix, Arizona

Arizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona

Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas

Southern California Permanente Medical Group, Downey, California

City of Hope Comprehensive Cancer Center, Duarte, California

Rebecca and John Moores UCSD Cancer Center, La Jolla, California

Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma Linda, California

Jonathan Jaques Children's Cancer Center at Miller Children's Hospital, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars-Sinai Comprehensive Cancer Center at Cedars-Sinai Medical Center, Los Angeles, California

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California

Children's Hospital Central California, Madera, California

Children's Hospital and Research Center at Oakland, Oakland, California

Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center, Orange, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital at Stanford University Medical Center, Palo Alto, California

Sutter Cancer Center, Sacramento, California

University of California Davis Cancer Center, Sacramento, California

Kaiser Permanente Medical Center - Sacramento, Sacramento, California

Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego, San Diego, California

Children's Hospital and Health Center, San Diego, San Diego, California

UCSF Comprehensive Cancer Center, San Francisco, California

Santa Barbara Cottage Hospital, Santa Barbara, California

Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California

David Grant Medical Center, Travis Air Force Base, California

Children's Hospital of Denver, Denver, Colorado

Presbyterian - St. Luke's Medical Center, Denver, Colorado

University of Connecticut Comprehensive Cancer Center at University of Connecticut Health Center, Farmington, Connecticut

Yale Comprehensive Cancer Center, New Haven, Connecticut

Alfred I. duPont Hospital for Children, Wilmington, Delaware

Lombardi Cancer Center at Georgetown University Medical Center, Washington, District of Columbia

Children's National Medical Center, Washington, District of Columbia

Broward General Medical Center, Fort Lauderdale, Florida

Children's Hospital of Southwest Florida, Fort Myers, Florida

Shands Cancer Center at the University of Florida Health Science Center, Gainesville, Florida

Joe DiMaggio Children's Hospital at Memorial, Hollywood, Florida

Nemours Children's Clinic, Jacksonville, Florida

Jackson Memorial Hospital, Miami, Florida

Miami Children's Hospital, Miami, Florida

Baptist-South Miami Regional Cancer Program, Miami, Florida

Florida Hospital Cancer Institute, Orlando, Florida

Nemours Children's Clinic-Orlando, Orlando, Florida

Sacred Heart Children's Hospital, Pensacola, Florida

All Children's Hospital, St. Petersburg, Florida

St. Joseph's Children's Hospital, Tampa, Florida

St. Mary's Hospital, West Palm Beach, Florida

AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus, Atlanta, Georgia

MBCCOP-Medical College of Georgia Cancer Center, Augusta, Georgia

Medical Center of Central Georgia, Macon, Georgia

Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center, Savannah, Georgia

Cancer Research Center of Hawaii, Honolulu, Hawaii

MBCCOP - Hawaii, Honolulu, Hawaii

Tripler Army Medical Center, Honolulu, Hawaii

Mountain States Tumor Institute - Boise, Boise, Idaho

University of Chicago Cancer Research Center, Chicago, Illinois

Rush University Medical Center, Chicago, Illinois

University of Illinois Medical Center, Chicago, Illinois

Children's Memorial Hospital - Chicago, Chicago, Illinois

Advocate Hope Children's Hospital, Oak Lawn, Illinois

Lutheran General Cancer Care Center, Park Ridge, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Riley Children Cancer Center at Riley Hospital for Children, Indianapolis, Indiana

St. Vincent Hospitals and Health Care Centers, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

John Stoddard Cancer Center at Iowa Methodist Medical Center, Des Moines, Iowa

Holden Comprehensive Cancer Center at University of Iowa, Iowa City, Iowa

Wesley Medical Center, Wichita, Kansas

Markey Cancer Center at University of Kentucky Chandler Medical Center, Lexington, Kentucky

Kosair Children's Hospital, Louisville, Kentucky

MBCCOP - LSU Health Sciences Center, New Orleans, Louisiana

Tulane Cancer Center at Tulane University Hospital and Clinic, New Orleans, Louisiana

Children's Hospital of New Orleans, New Orleans, Louisiana

Ochsner Clinic Foundation, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Maine Children's Cancer Program, Scarborough, Maine

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore, Maryland

Alvin and Lois Lapidus Cancer Institute at Sinai Hospital, Baltimore, Maryland

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland

Walter Reed Army Medical Center, Silver Spring, Maryland

Floating Hospital for Children, Boston, Massachusetts

Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts

Baystate Regional Cancer Program at Baystate Medical Center, Springfield, Massachusetts

UMASS Memorial Cancer Center - University Campus, Worcester, Massachusetts

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Children's Hospital of Michigan, Detroit, Michigan

Josephine Ford Cancer Center at Henry Ford Health System, Detroit, Michigan

Van Elslander Cancer Center at St. John Hospital and Medical Center, Detroit, Michigan

Hurley Medical Center, Flint, Michigan

Spectrum Health and DeVos Children's Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Breslin Cancer Center at Ingham Regional Medical Center, Lansing, Michigan

CCOP - Beaumont, Royal Oak, Michigan

William Beaumont Hospital - Royal Oak, Royal Oak, Michigan

St. Mary's - Duluth Clinic Cancer Center, Duluth, Minnesota

Children's Hospitals and Clinics - Minneapolis, Minneapolis, Minnesota

Mayo Clinic Cancer Center, Rochester, Minnesota

Children's Hospitals and Clinics - Minnesota, Saint Paul, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

Children's Mercy Hospital, Kansas City, Missouri

Cardinal Glennon Children's Hospital, Saint Louis, Missouri

St. Louis Children's Hospital, Saint Louis, Missouri

Children's Hospital of Omaha, Omaha, Nebraska

UNMC Eppley Cancer Center at the University of Nebraska Medical Center, Omaha, Nebraska

Sunrise Hospital and Medical Center, Las Vegas, Nevada

Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey

Cancer Institute of New Jersey at Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

St. Joseph's Hospital and Medical Center, Paterson, New Jersey

Valerie Fund Children's Center at Atlantic Health, Summit, New Jersey

University of New Mexico Cancer Research and Treatment Center, Albuquerque, New Mexico

Cancer Center of Albany Medical Center, Albany, New York

Albert Einstein Clinical Cancer Center, Bronx, New York

Brooklyn Hospital Center, Brooklyn, New York

SUNY Downstate Medical Center, Brooklyn, New York

Brookdale University Hospital and Medical Center, Brooklyn, New York

Comprehensive Cancer Center at Maimonides Medical Center, Brooklyn, New York

Schneider Children's Hospital, New Hyde Park, New York

Memorial Sloan-Kettering Cancer Center, New York, New York

New York Weill Cornell Cancer Center at Cornell University, New York, New York

Mount Sinai School of Medicine, New York, New York

Herbert Irving Comprehensive Cancer Center at Columbia University, New York, New York

James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester, New York

Long Island Cancer Center at Stony Brook University Hospital, Stony Brook, New York

SUNY Upstate Medical University Hospital, Syracuse, New York

New York Medical College, Valhalla, New York

Mission Hospitals, Asheville, North Carolina

Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill, North Carolina

Blumenthal Cancer Center at Carolinas Medical Center, Charlotte, North Carolina

Presbyterian Healthcare, Charlotte, North Carolina

Duke Comprehensive Cancer Center, Durham, North Carolina

Leo W. Jenkins Cancer Center of University Health Systems of Eastern Carolina, Greenville, North Carolina

Comprehensive Cancer Center at Wake Forest University, Winston-Salem, North Carolina

Dakota Cancer Institute at Innovis Health - Dakota Clinic, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University, Cleveland, Ohio

Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio

Columbus Children's Hospital, Columbus, Ohio

Children's Medical Center - Dayton, Dayton, Ohio

Toledo Children's Hospital, Toledo, Ohio

St. Vincent Mercy Medical Center, Toledo, Ohio

Forum Health-Tod Childrens Hospital, Youngstown, Ohio

Children's Hospital at Oklahoma University Medical Center, Oklahoma City, Oklahoma

CCOP - Oklahoma, Tulsa, Oklahoma

Natalie Warren Bryant Cancer Center, Tulsa, Oklahoma

CCOP - Columbia River Oncology Program, Portland, Oregon

Legacy Emanuel Hospital and Health Center & Children's Hospital, Portland, Oregon

Doernbecher Children's Hospital at Oregon Health & Science University, Portland, Oregon

Geisinger Medical Center, Danville, Pennsylvania

Penn State Cancer Institute at Milton S. Hershey Medical Center, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

St. Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Hollings Cancer Center at Medical University of South Carolina, Charleston, South Carolina

Palmetto Health South Carolina Cancer Center, Columbia, South Carolina

Children's Hospital of Greenville Hospital System, Greenville, South Carolina

Avera Cancer Institute, Sioux Falls, South Dakota

Sioux Valley Hospital at University of South Dakota Medical Center, Sioux Falls, South Dakota

East Tennessee State University Cancer Center at Johnson City Medical Center, Johnson City, Tennessee

East Tennessee Children's Hospital, Knoxville, Tennessee

St. Jude Children's Research Hospital, Memphis, Tennessee

Vanderbilt Children's Hospital, Nashville, Tennessee

Texas Tech University Health Sciences Center School of Medicine, Amarillo, Texas

Children's Hospital of Austin, Austin, Texas

Medical City Dallas Hospital, Dallas, Texas

Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas, Texas

Cook Children's Medical Center - Fort Worth, Fort Worth, Texas

University of Texas Medical Branch, Galveston, Texas

University of Texas - MD Anderson Cancer Center, Houston, Texas

Baylor College of Medicine, Houston, Texas

San Antonio Military Pediatric Cancer and Blood Disorders Center, Lackland Air Force Base, Texas

Covenant Children's Hospital, Lubbock, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

MBCCOP - South Texas Pediatrics, San Antonio, Texas

Methodist Cancer Center at Methodist Specialty and Transplant Hospital, San Antonio, Texas

CCOP - Scott and White Hospital, Temple, Texas

Center for Cancer Prevention and Care at Scott and White Clinic, Temple, Texas

Huntsman Cancer Institute, Salt Lake City, Utah

Vermont Cancer Center at University of Vermont, Burlington, Vermont

Cancer Center at the University of Virginia, Charlottesville, Virginia

Inova Fairfax Hospital, Falls Church, Virginia

Children's Hospital of the King's Daughters, Norfolk, Virginia

Naval Medical Center, Portsmouth, Portsmouth, Virginia

Massey Cancer Center at Virginia Commonwealth University, Richmond, Virginia

Carilion Medical Center for Children, Roanoke, Virginia

Children's Hospital and Regional Medical Center - Seattle, Seattle, Washington

Fred Hutchinson Cancer Research Center, Seattle, Washington

Group Health Central Hospital, Seattle, Washington

Deaconess Medical Center, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

West Virginia University - Robert C. Byrd Health Sciences Center - Charleston Division, Charleston, West Virginia

Cabell Huntington Hospital, Huntington, West Virginia

West Virginia University Hospitals, Morgantown, West Virginia

Bellin Memorial Hospital, Green Bay, Wisconsin

CCOP - St. Vincent Hospital Cancer Center, Green Bay, Green Bay, Wisconsin

St. Vincent Hospital, Green Bay, Wisconsin

Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center, La Crosse, Wisconsin

University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin

Marshfield Clinic, Marshfield, Wisconsin

CCOP - Marshfield Clinic Research Foundation, Marshfield, Wisconsin

Midwest Children's Cancer Center, Milwaukee, Wisconsin

Sydney Children's Hospital, Randwick, New South Wales

Children's Hospital at Westmead, Westmead, New South Wales

Royal Children's Hospital, Brisbane, Queensland

Women's and Children's Hospital, North Adelaide, South Australia

Royal Children's Hospital, Parkville, Victoria

Princess Margaret Hospital for Children, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

Cross Cancer Institute, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Children's Health and Rehabilitation Centre, St. John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Children's Hospital of Western Ontario, London, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

Montreal Children's Hospital at McGill University Health Center, Montreal, Quebec

Hopital Sainte Justine, Montreal, Quebec

Centre de Recherche du Centre Hospitalier de l'Universite Laval, Sainte Foy, Quebec

Allan Blair Cancer Centre at Pasqua Hospital, Regina, Saskatchewan

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Academisch Ziekenhuis Groningen, Groningen, Not set

Starship Children's Health, Auckland, Not set

Puerto Rico Cancer Center at University of Puerto Rico - Medical Sciences Campus, San Juan, Not set

San Jorge Childrens Hospital, Santurce, Not set

Swiss Pediatric Oncology Group Bern, Bern, Not set

Swiss Pediatric Oncology Group Geneva, Geneva, Not set

Swiss Pediatric Oncology Group Lausanne, Lausanne, Not set

Conditions: Neuroblastoma

Learn More ›

Combination Chemotherapy and Radiation Therapy in Treating Patients With Acute Lymphoblastic Leukemia That Has Relapsed in the CNS or Testes

NCT00096135

Completed

RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells. Giving combination chemotherapy together with radiation therapy may kill more cancer cells. PURPOSE: This clinical trial is studying how well giving chemotherapy together with radiation therapy works in treating patients with acute lymphoblastic leukemia that has relapsed in the CNS and/or testes.

Gender:

ALL

Ages:

Between 18 months and 29 years

Trial Updated:

02/14/2017

Locations: UAB Comprehensive Cancer Center, Birmingham, Alabama +152 locations

UAB Comprehensive Cancer Center, Birmingham, Alabama

Phoenix Children's Hospital, Phoenix, Arizona

Arizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona

Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas

Southern California Permanente Medical Group, Downey, California

City of Hope Comprehensive Cancer Center, Duarte, California

Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma Linda, California

Jonathan Jaques Children's Cancer Center at Miller Children's Hospital, Long Beach, California

Childrens Hospital Los Angeles, Los Angeles, California

Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, California

Children's Hospital Central California, Madera, California

Children's Hospital and Research Center Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital at Stanford University Medical Center, Palo Alto, California

Sutter Cancer Center, Sacramento, California

Kaiser Permanente Medical Center - Oakland, Sacramento, California

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California

Children's Hospital Center for Cancer and Blood Disorders, Aurora, Colorado

Presbyterian - St. Luke's Medical Center, Denver, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Alfred I. duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, District of Columbia

Broward General Medical Center Cancer Center, Fort Lauderdale, Florida

Lee Cancer Care of Lee Memorial Health System, Fort Myers, Florida

University of Florida Shands Cancer Center, Gainesville, Florida

Memorial Cancer Institute at Memorial Regional Hospital, Hollywood, Florida

Nemours Children's Clinic, Jacksonville, Florida

University of Miami Sylvester Comprehensive Cancer Center - Miami, Miami, Florida

Miami Children's Hospital, Miami, Florida

Baptist-South Miami Regional Cancer Program, Miami, Florida

Florida Hospital Cancer Institute at Florida Hospital Orlando, Orlando, Florida

M.D. Anderson Cancer Center at Orlando, Orlando, Florida

Nemours Children's Clinic - Orlando, Orlando, Florida

Sacred Heart Cancer Center at Sacred Heart Hospital, Pensacola, Florida

All Children's Hospital, Saint Petersburg, Florida

St. Joseph's Cancer Institute at St. Joseph's Hospital, Tampa, Florida

Kaplan Cancer Center at St. Mary's Medical Center, West Palm Beach, Florida

AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus, Atlanta, Georgia

Cancer Research Center of Hawaii, Honolulu, Hawaii

Mountain States Tumor Institute at St. Luke's Regional Medical Center, Boise, Idaho

University of Illinois Cancer Center, Chicago, Illinois

Cardinal Bernardin Cancer Center at Loyola University Medical Center, Maywood, Illinois

Keyser Family Cancer Center at Advocate Hope Children's Hospital, Oak Lawn, Illinois

Advocate Lutheran General Cancer Care Center, Park Ridge, Illinois

Simmons Cooper Cancer Institute, Springfield, Illinois

Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana

St. Vincent Indianapolis Hospital, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

Holden Comprehensive Cancer Center at University of Iowa, Iowa City, Iowa

Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center, Kansas City, Kansas

Lucille P. Markey Cancer Center at University of Kentucky, Lexington, Kentucky

Kosair Children's Hospital, Louisville, Kentucky

CancerCare of Maine at Eastern Maine Medical Center, Bangor, Maine

Alvin and Lois Lapidus Cancer Institute at Sinai Hospital, Baltimore, Maryland

Floating Hospital for Children at Tufts - New England Medical Center, Boston, Massachusetts

C.S. Mott Children's Hospital at University of Michigan Medical Center, Ann Arbor, Michigan

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan

Hurley Medical Center, Flint, Michigan

Butterworth Hospital at Spectrum Health, Grand Rapids, Michigan

Van Elslander Cancer Center at St. John Hospital and Medical Center, Grosse Pointe Woods, Michigan

CCOP - Kalamazoo, Kalamazoo, Michigan

Breslin Cancer Center at Ingham Regional Medical Center, Lansing, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

Mayo Clinic Cancer Center, Rochester, Minnesota

University of Mississippi Cancer Clinic, Jackson, Mississippi

Ellis Fischel Cancer Center at University of Missouri - Columbia, Columbia, Missouri

Children's Mercy Hospital, Kansas City, Missouri

CCOP - Nevada Cancer Research Foundation, Las Vegas, Nevada

Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

Hackensack University Medical Center Cancer Center, Hackensack, New Jersey

Overlook Hospital, Morristown, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

St. Joseph's Hospital and Medical Center, Paterson, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albert Einstein Cancer Center at Albert Einstein College of Medicine, Bronx, New York

Brooklyn Hospital Center, Brooklyn, New York

Maimonides Cancer Center at Maimonides Medical Center, Brooklyn, New York

Roswell Park Cancer Institute, Buffalo, New York

Winthrop University Hospital, Mineola, New York

Schneider Children's Hospital, New Hyde Park, New York

NYU Cancer Institute at New York University Medical Center, New York, New York

Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, New York, New York

James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester, New York

Stony Brook University Cancer Center, Stony Brook, New York

SUNY Upstate Medical University Hospital, Syracuse, New York

New York Medical College, Valhalla, New York

Blumenthal Cancer Center at Carolinas Medical Center, Charlotte, North Carolina

Presbyterian Cancer Center at Presbyterian Hospital, Charlotte, North Carolina

Duke Comprehensive Cancer Center, Durham, North Carolina

Wake Forest University Comprehensive Cancer Center, Winston-Salem, North Carolina

CCOP - MeritCare Hospital, Fargo, North Dakota

Akron Children's Hospital, Akron, Ohio

Rainbow Babies and Children's Hospital, Cleveland, Ohio

Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's - Dayton, Dayton, Ohio

Medical University of Ohio Cancer Center, Toledo, Ohio

Tod Children's Hospital, Youngstown, Ohio

Oklahoma University Cancer Institute, Oklahoma City, Oklahoma

Legacy Emanuel Hospital and Health Center and Children's Hospital, Portland, Oregon

Knight Cancer Institute at Oregon Health and Science University, Portland, Oregon

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Geisinger Cancer Institute at Geisinger Health, Danville, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

St. Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital Comprehensive Cancer Center, Providence, Rhode Island

Hollings Cancer Center at Medical University of South Carolina, Charleston, South Carolina

Greenville Hospital Cancer Center, Greenville, South Carolina

Sanford Cancer Center at Sanford USD Medical Center, Sioux Falls, South Dakota

T.C. Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Children's Hospital, Knoxville, Tennessee

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee

Texas Tech University Health Sciences Center School of Medicine - Amarillo, Amarillo, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas, Texas

Cook Children's Medical Center - Fort Worth, Fort Worth, Texas

Baylor University Medical Center - Houston, Houston, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

Primary Children's Medical Center, Salt Lake City, Utah

Fletcher Allen Health Care - University Health Center Campus, Burlington, Vermont

Inova Fairfax Hospital, Falls Church, Virginia

Carilion Medical Center for Children at Roanoke Community Hospital, Roanoke, Virginia

Providence Cancer Center at Sacred Heart Medical Center, Spokane, Washington

West Virginia University Health Sciences Center - Charleston, Charleston, West Virginia

Mary Babb Randolph Cancer Center at West Virginia University Hospitals, Morgantown, West Virginia

St. Vincent Hospital Regional Cancer Center, Green Bay, Wisconsin

Gundersen Lutheran Center for Cancer and Blood, La Crosse, Wisconsin

Marshfield Clinic - Marshfield Center, Marshfield, Wisconsin

Midwest Children's Cancer Center at Children's Hospital of Wisconsin, Milwaukee, Wisconsin

Princess Margaret Hospital for Children, Perth, Western Australia

University of Alberta Hospital, Edmonton, Alberta

Children's & Women's Hospital of British Columbia, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Children's Health and Rehabilitation Centre, St. John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Cancer Centre of Southeastern Ontario at Kingston General Hospital, Kingston, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hopital Sainte Justine, Montreal, Quebec

Allan Blair Cancer Centre at Pasqua Hospital, Regina, Saskatchewan

Saskatoon Cancer Centre at the University of Saskatchewan, Saskatoon, Saskatchewan

Centre Hospitalier Universitaire de Quebec, Quebec, Not set

Starship Children's Health, Auckland, Not set

Christchurch Hospital, Christchurch, Not set

Swiss Pediatric Oncology Group Bern, Bern, Not set

Swiss Pediatric Oncology Group Geneva, Geneva, Not set

Swiss Pediatric Oncology Group Lausanne, Lausanne, Not set

Conditions: Leukemia

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Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia

NCT00002744

Completed

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug and giving them in different ways may kill more cancer cells. It is not yet known which regimen of combination chemotherapy is more effective for acute lymphoblastic leukemia PURPOSE: Randomized phase III trial to compare different regimens of combination chemotherapy in treating children who have newly diagnosed acute lymphoblastic leukemia.

Gender:

ALL

Ages:

Between 1 year and 9 years

Trial Updated:

02/07/2017

Locations: Long Beach Memorial Medical Center, Long Beach, California +33 locations

Long Beach Memorial Medical Center, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California

Children's Hospital of Orange County, Orange, California

UCSF Cancer Center and Cancer Research Institute, San Francisco, California

Children's Hospital of Denver, Denver, Colorado

Children's National Medical Center, Washington, District of Columbia

University of Chicago Cancer Research Center, Chicago, Illinois

Indiana University Cancer Center, Indianapolis, Indiana

University of Iowa Hospitals and Clinics, Iowa City, Iowa

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

University of Minnesota Cancer Center, Minneapolis, Minnesota

Mayo Clinic Cancer Center, Rochester, Minnesota

Children's Mercy Hospital - Kansas City, Kansas City, Missouri

University of Nebraska Medical Center, Omaha, Nebraska

Kaplan Cancer Center, New York, New York

Memorial Sloan-Kettering Cancer Center, New York, New York

Herbert Irving Comprehensive Cancer Center, New York, New York

Lineberger Comprehensive Cancer Center, UNC, Chapel Hill, North Carolina

Children's Hospital Medical Center - Cincinnati, Cincinnati, Ohio

Ireland Cancer Center, Cleveland, Ohio

Children's Hospital of Columbus, Columbus, Ohio

Doernbecher Children's Hospital, Portland, Oregon

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania

Vanderbilt Cancer Center, Nashville, Tennessee

University of Texas - MD Anderson Cancer Center, Houston, Texas

Huntsman Cancer Institute, Salt Lake City, Utah

Children's Hospital and Medical Center - Seattle, Seattle, Washington

Fred Hutchinson Cancer Research Center, Seattle, Washington

University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin

Princess Margaret Hospital for Children, Perth, Western Australia

British Columbia Children's Hospital, Vancouver, British Columbia

IWK Grace Health Centre, Halifax, Nova Scotia

Conditions: Leukemia

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Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

NCT00873093

Completed

This pilot, phase II trial studies the side effects of giving bortezomib together with combination chemotherapy and to see how well it works in treating young patients with relapsed acute lymphoblastic leukemia or lymphoblastic lymphoma. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving bor... Read More

Gender:

ALL

Ages:

Between 1 year and 31 years

Trial Updated:

11/30/2016

Locations: Children's Hospital of Alabama, Birmingham, Alabama +170 locations

Children's Hospital of Alabama, Birmingham, Alabama

University of Alabama at Birmingham, Birmingham, Alabama

Phoenix Childrens Hospital, Phoenix, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

Southern California Permanente Medical Group, Downey, California

City of Hope Medical Center, Duarte, California

City of Hope, Duarte, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's Hospital, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars-Sinai Medical Center, Los Angeles, California

Children's Hospital Central California, Madera, California

Children's Hospital and Research Center at Oakland, Oakland, California

Kaiser Permanente-Oakland, Oakland, California

Childrens Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

University of California at Davis Cancer Center, Sacramento, California

Rady Children's Hospital - San Diego, San Diego, California

University of California San Francisco Medical Center-Parnassus, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, District of Columbia

Lombardi Comprehensive Cancer Center at Georgetown University, Washington, District of Columbia

Broward Health Medical Center, Fort Lauderdale, Florida

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

Memorial Healthcare System - Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville South, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Florida Hospital, Orlando, Florida

UF Cancer Center at Orlando Health, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

All Children's Hospital, Saint Petersburg, Florida

Saint Joseph Children's Hospital of Tampa, Tampa, Florida

Saint Mary's Hospital, West Palm Beach, Florida

Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia

Memorial University Medical Center, Savannah, Georgia

University of Hawaii Cancer Center, Honolulu, Hawaii

Saint Luke's Mountain States Tumor Institute, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Southern Illinois University, Springfield, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Saint Vincent Hospital and Health Services, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa Hospitals and Clinics, Iowa City, Iowa

University of Kentucky, Lexington, Kentucky

Kosair Children's Hospital, Louisville, Kentucky

Tulane University Health Sciences Center, New Orleans, Louisiana

Children's Hospital New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Floating Hospital for Children at Tufts Medical Center, Boston, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Saint John Hospital and Medical Center, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Hurley Medical Center, Flint, Michigan

Helen DeVos Children's Hospital at Spectrum Health, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Kalamazoo Center for Medical Studies, Kalamazoo, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

Mayo Clinic, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

Columbia Regional, Columbia, Missouri

The Childrens Mercy Hospital, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Saint John's Mercy Medical Center, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Nevada Cancer Research Foundation CCOP, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Morristown Memorial Hospital, Morristown, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

UMDNJ - Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Overlook Hospital, Summit, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

University of New Mexico, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

Winthrop University Hospital, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

New York University Langone Medical Center, New York, New York

Columbia University Medical Center, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

Mission Hospital-Memorial Campus, Asheville, North Carolina

University of North Carolina, Chapel Hill, North Carolina

Carolinas Medical Center, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Medical Center-Fargo, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

The Toledo Hospital/Toledo Children's Hospital, Toledo, Ohio

Mercy Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Natalie Warren Bryant Cancer Center at Saint Francis, Tulsa, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Legacy Emanuel Hospital and Health Center, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Geisinger Medical Center, Danville, Pennsylvania

Penn State Hershey Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Medical University of South Carolina, Charleston, South Carolina

Palmetto Health Richland, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Greenville Cancer Treatment Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

Vanderbilt-Ingram Cancer Center, Nashville, Tennessee

Texas Tech University Health Science Center-Amarillo, Amarillo, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

Brooke Army Medical Center, Fort Sam Houston, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont, Burlington, Vermont

University of Virginia, Charlottesville, Virginia

Childrens Hospital-King's Daughters, Norfolk, Virginia

Virginia Commonwealth University, Richmond, Virginia

Carilion Clinic Children's Hospital, Roanoke, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

West Virginia University Charleston, Charleston, West Virginia

Saint Vincent Hospital, Green Bay, Wisconsin

University of Wisconsin Hospital and Clinics, Madison, Wisconsin

Midwest Children's Cancer Center, Milwaukee, Wisconsin

Princess Margaret Hospital for Children, Perth, Western Australia

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Child Health Centre, Saint John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Chedoke-McMaster Hospitals, Hamilton, Ontario

Cancer Centre of Southeastern Ontario at Kingston General Hospital, Kingston, Ontario

Children's Hospital, London, Ontario

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

San Jorge Children's Hospital, San Juan, Not set

Conditions: B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Lymphoblastic Lymphoma, T-cell Adult Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic Leukemia

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