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Dexamethasone Treatment Options in Canada
A collection of 294 research studies where Dexamethasone is the interventional treatment. These studies are located in the Canada . Dexamethasone is used for conditions such as Multiple Myeloma, Postoperative Pain and Lymphoma.
157 - 168 of 294
Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Newly Diagnosed, Previously Untreated Multiple Myeloma
Completed
The purpose of the study is to determine whether the addition of Elotuzumab to Lenalidomide/low-dose Dexamethasone will increase the progression free survival (PFS)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/02/2022
Locations: Local Institution - 1628, Birmingham, Alabama +234 locations
Conditions: Multiple Myeloma
Hormone Therapy and Radiation Therapy or Hormone Therapy and Radiation Therapy Followed by Docetaxel and Prednisone in Treating Patients With Localized Prostate Cancer
Completed
RATIONALE: Androgens can cause the growth of prostate cancer cells. Hormone therapy using drugs, such as leuprolide, goserelin, flutamide, or bicalutamide, may fight prostate cancer by lowering the amount of androgens the body makes. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as docetaxel and prednisone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known... Read More
Gender:
MALE
Ages:
Between 18 years and 120 years
Trial Updated:
05/23/2022
Locations: UAB Comprehensive Cancer Center, Birmingham, Alabama +253 locations
Conditions: Prostate Cancer
Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Relapsed or Refractory Multiple Myeloma
Completed
The purpose of the study is to determine whether the addition of Elotuzumab to Lenalidomide/low-dose Dexamethasone will increase the progression free survival (PFS).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2022
Locations: Northwest Alabama Cancer Center, Pc, Muscle Shoals, Alabama +215 locations
Conditions: Lymphoma, Multiple Myeloma
IPACK Study in Total Knee Arthroplasty Patients
Completed
This study proposes to compare current multimodal analgesic treatment for TKA with a new multimodal analgesic regimen to demonstrate decreased opioid requirement, time to rehabilitation, and time to reach hospital discharge.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
04/25/2022
Locations: Toronto Western Hopspital, Toronto, Ontario
Conditions: Knee Replacement Arthroplasty
Mechanical Diagnosis and Treatment and/or Steroid Injections for Lumbar Radiculopathy
Terminated
Aim 1: The primary aim of this study is to test the feasibility of Mechanical Diagnosis and Treatment (MDT) +/- transforaminal epidural steroid injections (TESI) on pain and disability in patients awaiting physiatry consult for lumbar radiculopathy secondary to lumbar disc herniation, compared to usual care within the current healthcare system in Calgary, Alberta, Canada.
Hypothesis: the investigators hypothesise that centralisers treated with MDT and non-centralisers receiving TESIs + MDT will... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/01/2022
Locations: Buenavista Physiotherapy, Calgary, Alberta
Conditions: Sciatica, Lumbosacral Radiculopathy, Lumbar Disc Rupture
Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Orchiopexy Repair
Completed
Surgical intervention to treat undescended testis is a very common pediatric surgical procedure, often performed using an inguinal incision or subscrotal incision approach. Children who undergo orchiopexy can suffer from a significant degree of discomfort postoperatively. The investigators are evaluating the effectiveness of an ultrasound guided caudal-epidural (CE) block to an US guided ilioinguinal/iliohypogastric (IIG/IHG) nerve block in achieving post operative analgesia following a orchiope... Read More
Gender:
MALE
Ages:
Between 6 months and 4 years
Trial Updated:
02/14/2022
Locations: Alberta Children's Hospital, Calgary, Alberta
Conditions: Testicle Undescended, Pain, Postoperative
Study of BTK Inhibitor, Ibrutinib in Combination With Carfilzomib in Subjects With Relapsed and Refractory Multiple Myeloma
Completed
A MULTICENTER PHASE 1/2B STUDY OF THE BRUTON'S TYROSINE KINASE INHIBITOR, IBRUTINIB (PCI-32765), IN COMBINATION WITH CARFILZOMIB (KYPROLIS™) IN SUBJECTS WITH RELAPSED OR RELAPSED AND REFRACTORY MULTIPLE MYELOMA
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/24/2021
Locations: City of Hope, Duarte, California +16 locations
Conditions: Multiple Myeloma
Randomized Study of Preoperative Dexamethasone for Quality of Recovery in VATS Lung Resection Patients
Completed
The proposed study is a randomized, double-blind, placebo-controlled evaluation if a small dose of IV dexamethasone during induction anesthesia in association to pre and postoperative intercostal nerve block, improves quality of recovery of thoracoscopic lung resection patients.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
08/24/2021
Locations: Institut Universitaire de Cardiologie et de Pneumologie de Québec, IUCPQ, Québec, Not set +1 locations
Conditions: Lung Cancer
Daunorubicin, Cytarabine, and Midostaurin in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Unknown
The purpose of this study is to compare the effects, good and/or bad, of a standard chemotherapy regimen for AML that includes the drugs daunorubicin and cytarabine combined with or without midostaurin (also known as PKC412), to find out which is better. This research is being done because it is unknown whether the addition of midostaurin to chemotherapy treatment is better than chemotherapy treatment alone. Midostaurin has been tested in over 400 patients and is being studied in a number of ill... Read More
Gender:
ALL
Ages:
Between 18 years and 59 years
Trial Updated:
08/16/2021
Locations: UAB Comprehensive Cancer Center, Birmingham, Alabama +175 locations
Conditions: Leukemia
Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy
Completed
The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, lidocaine, and gabapentin can help reduce postoperative respiratory depression in the post-anesthesia care unit and ward in children with sleep-disordered breathing undergoing tonsillectomy when compared with traditional opioid-containing techniques. It is expected that this OFA regimen will have a measurable reduction on postoperative respiratory depression... Read More
Gender:
ALL
Ages:
12 years and below
Trial Updated:
08/06/2021
Locations: Royal University Hospital, Saskatoon, Saskatchewan
Conditions: Anesthesia, General Anesthesia, Analgesics, Opioid, Postoperative Complications, Pathologic Processes, Physiologic Effects of Drugs, Narcotics, Analgesics, Sleep Disordered Breathing, Obstructive Sleep Apnea of Child, Tonsillectomy, Respiratory Depression, Dexmedetomidine, Ketamine, Lidocaine, Gabapentin, Pulse Oximetry
A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First- Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)
Terminated
This is a Phase 3, randomized, double-blind, placebo-controlled, multinational, and multicenter study to evaluate the efficacy of rovalpituzumab tesirine as maintenance therapy following first-line platinum-based chemotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2021
Locations: Clearview Cancer Institute /ID# 156699, Huntsville, Alabama +307 locations
Conditions: Small Cell Lung Cancer
Tailoring Treatment for B Cell Non-hodgkin's Lymphoma Based on PET Scan Results Mid Treatment
Unknown
The purpose of this study is to assess whether patients who are likely to fail R-CHOP, as predicted by a mid-treatment PET scan, can have an improved outcome if switched to a standard salvage regimen R-ICE (rituximab, ifosfamide, carboplatin, etoposide).
Patients who have a negative PET scan after 4 cycles of R-CHOP have an excellent prognosis (\>85% chance of cure) and should complete treatment with 6 cycles of standard R-CHOP. Patients who have a positive PET scan after 4 cycles of R-CHOP hav... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/20/2021
Locations: BC Cancer Agency, Vancouver, British Columbia
Conditions: Lymphoma, Non-Hodgkin, Advanced Stage Diffuse Large B-Cell Non-Hodgkin's Lymphoma
157 - 168 of 294