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Paclitaxel Treatment Options in Canada
A collection of 344 research studies where Paclitaxel is the interventional treatment. These studies are located in the Canada . Paclitaxel is used for conditions such as Breast Cancer, Ovarian Cancer and Non-Small Cell Lung Cancer.
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Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49)
Active Not Recruiting
The safety and efficacy of pembrolizumab plus the investigator's choice of chemotherapy will be assessed compared to placebo plus the investigator's choice of chemotherapy in the treatment of chemotherapy-candidate hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-) locally recurrent inoperable or metastatic breast cancer.
The primary hypotheses are that the combination of pembrolizumab and chemotherapy is superior to placebo and chemotherapy in regards to P... Read More
The safety and efficacy of pembrolizumab plus the investigator's choice of chemotherapy will be assessed compared to placebo plus the investigator's choice of chemotherapy in the treatment of chemotherapy-candidate hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-) locally recurrent inoperable or metastatic breast cancer.
The primary hypotheses are that the combination of pembrolizumab and chemotherapy is superior to placebo and chemotherapy in regards to Progression-Free Survival (PFS) in participants with programmed cell death-ligand 1 (PD-L1) combined positive score (CPS) ≥1. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2025
Locations: University of Alabama at Birmingham-Medicine ( Site 0065), Birmingham, Alabama +255 locations
University of Alabama at Birmingham-Medicine ( Site 0065), Birmingham, Alabama
Arizona Oncology Associates-Arizona Oncology ( Site 0049), Tucson, Arizona
Pacific Cancer Care ( Site 0023), Monterey, California
UCSF Medical Center at Mission Bay ( Site 0043), San Francisco, California
Georgetown University Medical Center-Department of Medicine and Oncology ( Site 0026), Washington, District of Columbia
MedStar Washington Hospital Center ( Site 0063), Washington, District of Columbia
Baptist MD Anderson Cancer Center ( Site 0013), Jacksonville, Florida
Miami Cancer Institute at Baptist Health, Inc. ( Site 0070), Miami, Florida
Miami Cancer Institute - Plantation ( Site 0076), Plantation, Florida
University Cancer & Blood Center, LLC ( Site 0032), Athens, Georgia
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 0028), Marietta, Georgia
University of Illinois at Chicago ( Site 0061), Chicago, Illinois
Edward-Elmhurst Healthcare, Elmhurst Hospital-Nancy W. Knowles Cancer Center ( Site 0067), Elmhurst, Illinois
Edward-Elmhurst Healthcare, Edward Hospital-Edward Cancer Center ( Site 0066), Naperville, Illinois
Edward-Elmhurst Healthcare, Edward Hospital - Plainfield-Edward Cancer Center - Plainfield ( Site 00, Plainfield, Illinois
Orchard Healthcare Research Inc. ( Site 0037), Skokie, Illinois
Parkview Research Center at Parkview Regional Medical Center ( Site 0071), Fort Wayne, Indiana
McFarland Clinic, PC ( Site 0041), Ames, Iowa
Louisiana State University Health Sciences Shreveport ( Site 0072), Shreveport, Louisiana
CHRISTUS Highland-Oncology Research ( Site 0073), Shreveport, Louisiana
New England Cancer Specialists ( Site 0007), Scarborough, Maine
Greater Baltimore Medical Center-Medical Oncology/Hematology ( Site 0062), Baltimore, Maryland
MFSMC-HJWCI ( Site 0064), Baltimore, Maryland
MedStar Good Samaritan Hospital-Oncology Research ( Site 0069), Baltimore, Maryland
University of Massachusetts Medical School-Division of Hematology/Oncology ( Site 0052), Worcester, Massachusetts
Henry Ford Hospital ( Site 0003), Detroit, Michigan
Oncology Hematology West, PC dba Nebraska Cancer Specialists ( Site 0009), Omaha, Nebraska
Broome Oncology ( Site 0018), Johnson City, New York
Hematology Oncology Associates of Rockland ( Site 0044), Nyack, New York
Waverly Hematology Oncology ( Site 0015), Cary, North Carolina
Sanford Fargo Medical Center ( Site 0040), Fargo, North Dakota
Providence Portland Medical Center ( Site 0038), Portland, Oregon
Oregon Health and Science University ( Site 0031), Portland, Oregon
St Francis Cancer Center ( Site 0058), Greenville, South Carolina
Sanford Cancer Center ( Site 0021), Sioux Falls, South Dakota
University of Tennessee Medical Center ( Site 0039), Knoxville, Tennessee
Bon Secours St. Francis Medical Center-Oncology Research ( Site 0020), Midlothian, Virginia
Kadlec Clinic Hematology and Oncology ( Site 0055), Kennewick, Washington
Medical Oncology Associates, PS ( Site 0010), Spokane, Washington
Northwest Medical Specialties, PLLC ( Site 0008), Tacoma, Washington
North Star Lodge ( Site 0035), Yakima, Washington
Centro de Oncología e Investigación de Buenos Aires ( Site 0400), Berazategui, Buenos Aires
Hospital Británico de Buenos Aires-Oncology ( Site 0404), Ciudad autónoma de Buenos Aires, Buenos Aires
Instituto de Investigaciones Clínicas Mar del Plata ( Site 0412), Mar del Plata, Buenos Aires
Hospital Aleman-Oncology ( Site 0402), Buenos Aires, Caba
Centro de Educación Médica e Investigaciones Clínicas (CEMIC) ( Site 0403), Buenos Aires, Caba
Sanatorio de La Mujer ( Site 0405), Rosario, Santa Fe
Sanatorio Parque ( Site 0407), Rosario, Santa Fe
Instituto de Oncología de Rosario ( Site 0401), Rosario, Santa Fe
Hospital Italiano de Córdoba ( Site 0409), Cordoba, Not set
Fundación CEMAIC ( Site 0410), Cordoba, Not set
Instituto San Marcos ( Site 0408), San Juan, Not set
Macquarie University-MQ Health Clinical Trials Unit ( Site 2102), Macquarie Park, New South Wales
Westmead Hospital-Department of Medical Oncology ( Site 2101), Westmead, New South Wales
Frankston Hospital-Oncology and Haematology ( Site 2103), Frankston, Victoria
Breast Cancer Research Centre-WA ( Site 2104), Nedlands, Western Australia
Landesklinikum Wiener Neustadt-Innere Medizin, Hämatologie und internistische Onkologie ( Site 1604), Wiener Neustadt, Niederosterreich
Medizinische Universität Graz-Innere Medizin Klin. Abt. Onkologie ( Site 1609), Graz, Steiermark
Medizinische Universitaet Innsbruck ( Site 1602), Innsbruck, Tirol
Medizinische Universität Wien ( Site 1601), Vienna, Wien
Uniklinikum Salzburg-Universitätsklinik für Innere Medizin III der PMU mit Hämatologie, internistis, Salzburg, Not set
Hospital de Câncer de Recife ( Site 0211), Recife, Pernambuco
Instituto de Oncologia Saint Gallen ( Site 0206), Santa Cruz do Sul, Rio Grande Do Sul
Clínica de Oncologia Reichow ( Site 0210), Blumenau, Santa Catarina
YNOVA Pesquisa Clínica ( Site 0203), Florianópolis, Santa Catarina
Instituto Nacional de Câncer - INCA-Pesquisa Clinica HC3 ( Site 0208), Rio de Janeiro, Not set
Instituto de Educação, Pesquisa e Gestão em Saúde ( Site 0202), Rio de Janeiro, Not set
Tom Baker Cancer Center ( Site 0107), Calgary, Alberta
North York General Hospital ( Site 0108), Toronto, Ontario
Princess Margaret Cancer Centre ( Site 0101), Toronto, Ontario
Jewish General Hospital ( Site 0110), Montreal, Quebec
Centre Hospitalier de l'Université de Montréal ( Site 0105), Montréal, Quebec
Hopital Du Saint-Sacrement ( Site 0109), Quebec City, Quebec
Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-centre-du-quebec (, Trois-Rivières, Quebec
Centro Investigación del Cáncer James Lind ( Site 0513), Temuco, Araucania
FALP ( Site 0501), Santiago, Region M. De Santiago
Oncovida ( Site 0514), Santiago, Region M. De Santiago
Clínica RedSalud Vitacura ( Site 0515), Santiago, Region M. De Santiago
Instituto Nacional del Cancer-CR Investigación ( Site 0511), Santiago, Region M. De Santiago
Bradfordhill ( Site 0500), Santiago, Region M. De Santiago
Anhui Cancer Hospital-medical oncology ( Site 2632), Hefei, Anhui
Cancer Hospital Chinese Academy of Medical Science ( Site 2635), Beijing, Beijing
Beijing Cancer hospital-Department of Breast Cancer ( Site 2605), Beijing, Beijing
Beijing Peking Union Medical College Hospital-Medical Oncology ( Site 2610), Beijing, Beijing
The First Affiliated hospital of Xiamen University-Breast Surgery ( Site 2613), Xiamen, Fujian
The First People's Hospital of Foshan-Oncology Department of Breast Cancer ( Site 2620), Foshan, Guangdong
SUN YAT-SEN UNIVERSITY CANCER CENTRE-oncology breast ( Site 2616), Guangzhou, Guangdong
Sun Yat-sen Memorial Hospital, Sun Yat-sen University-Breast Oncology Center ( Site 2641), Guangzhou, Guangdong
Peking University Shenzhen Hospital-Oncology Department ( Site 2601), Shenzhen, Guangdong
Guangxi Medical University Affiliated Tumor Hospital-Oncology Dept. of Breast and Bone Soft Tissue (, Nanning, Guangxi
Henan Cancer Hospital-Galactophore Department ( Site 2615), Zhengzhou, Henan
Wuhan Union Hospital Cancer Center-Cancer Center ( Site 2629), Wuhan, Hubei
Xiangya Hospital Central South University-Breast department ( Site 2621), Changsha, Hunan
Hunan Cancer Hospital ( Site 2608), Changsha, Hunan
Jiangsu provincial people's hospital-Oncology Department ( Site 2607), Nanjing, Jiangsu
The Third Hospital of Nanchang-Oncology Dept ( Site 2628), Nanchang, Jiangxi
Jilin Cancer Hospital-oncology department ( Site 2619), Changchun, Jilin
The First Affiliated Hospital of Xian Jiaotong University wa-Oncology ( Site 2604), Xi'an, Shaanxi
Shandong Cancer Hospital-Breast surgery ( Site 2623), Jinan, Shandong
Fudan University Shanghai Cancer Center-Oncology ( Site 2600), Shanghai, Shanghai
Renji Hospital Shanghai Jiao Tong University School of Medicine-Breast surgery ( Site 2626), Shanghai, Shanghai
West China Hospital Sichuan University-Head and Neck Oncology ( Site 2630), Cheng Du, Sichuan
Tianjin Medical University Cancer Institute and Hospital-Department of Breast Cancer ( Site 2612), Tianjin, Tianjin
Xinjiang Medical University Cancer Hospital - Urumqi-galactophore department ( Site 2624), Urumqi, Xinjiang
Zhejiang Cancer Hospital-Breast Oncology ( Site 2622), Hangzhou, Zhejiang
Taizhou Hospital of Zhejiang Province ( Site 2636), Linhai, Zhejiang
The First Affiliated Hospital of Wenzhou Medical University-Thyroid and breast surgery ( Site 2625), Wenzhou, Zhejiang
Fundación Colombiana de Cancerología Clínica Vida ( Site 0605), Medellín, Antioquia
Instituto de Cancerología-Oncology ( Site 0606), Medellín, Antioquia
Clinica de la Costa S.A.S. ( Site 0601), Barranquilla, Atlantico
Sociedad De Oncologia Y Hematologia Del Cesar-Oncology ( Site 0603), Valledupar, Cesar
Oncomedica S.A.-Oncomedica S.A ( Site 0604), Montería, Cordoba
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia ( Site 0607), Bogota, Distrito Capital De Bogota
Institut Paoli-Calmettes ( Site 0913), Marseille, Bouches-du-Rhone
Centre François Baclesse ( Site 0920), Caen, Calvados
CHU Besançon ( Site 0918), Besançon, Franche-Comte
Institut Claudius Regaud ( Site 0902), Toulouse, Haute-Garonne
Gustave Roussy ( Site 0914), Villejuif, Ile-de-France
Centre de Cancérologie du Grand Montpellier ( Site 0912), Montpellier, Languedoc-Roussillon
Institut de Cancérologie de l'Ouest ( Site 0907), Saint Herblain, Loire-Atlantique
Institut de Cancérologie de l'Ouest ( Site 0915), ANGERS cedex 02, Maine-et-Loire
Centre Oscar Lambret ( Site 0921), Lille, Nord
Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne ( Site 0901), Clermont-Ferrand, Puy-de-Dome
CENTRE LEON BERARD ( Site 0919), Lyon, Rhone-Alpes
Centre de Lutte Contre le Cancer - Centre Henri Becquerel Normandie Rouen ( Site 0904), Rouen, Seine-Maritime
Centre Hospitalier Universitaire de Poitiers-Pôle régional de cancérologie ( Site 0922), Poitiers, Vienne
Institut Curie ( Site 0900), Paris, Not set
Universitaetsklinikum Erlangen-Klinik für Gynäkologie und Geburtshilfe ( Site 1202), Erlangen, Bayern
Gynaekologisches Zentrum Bonn ( Site 1201), Bonn, Nordrhein-Westfalen
Universitaetsklinikum Duesseldorf-Klinik für Frauenheilkunde & Geburtshilfe ( Site 1204), Düsseldorf, Nordrhein-Westfalen
Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung-Klinike für Senologie/ Brustzentrum ( Site 1200, Essen, Nordrhein-Westfalen
Universitaetsklinikum Carl Gustav Carus Dresden-Klinik und Poliklinik für Frauenheilkunde und Gebur, Dresden, Sachsen
Vivantes Klinikum Am Urban-Haematologie und Onkologie ( Site 1203), Berlin, Not set
General Hospital of Athens Laiko-First Department of Internal Medicine ( Site 0305), Athens, Attiki
Alexandra Hospital-ONCOLGOY DEPT. ( Site 0302), Athens, Attiki
Hygeia Hospital-3rd Oncology Department ( Site 0304), Marousi, Attiki
University General Hospital of Heraklion-Internal Medicine-Oncology ( Site 0303), Heraklion, Irakleio
Euromedica General Clinic Thessaloniki-Oncology Unit ( Site 0301), Thessaloniki, Not set
CELAN,S.A ( Site 0151), Guatemala, Not set
Gastrosoluciones ( Site 0156), Guatemala, Not set
INTEGRA Cancer Institute ( Site 0155), Guatemala, Not set
Centro Medico Integral De Cancerología (CEMIC) ( Site 0154), Quetzaltenango, Not set
Bacs-Kiskun Megyei Korhaz-Onkoradiologiai Kozpont ( Site 2804), Kecskemét, Bacs-Kiskun
Pécsi Tudományegyetem Klinikai Központ-Onkoterápiás Intézet ( Site 2807), Pécs, Baranya
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Onkoterapias Klinika ( Site 2805), Szeged, Csongrad
St. James's Hospital ( Site 1530), Dublin, Not set
St. Vincent's University Hospital-Medical Oncology Research Department ( Site 1531), Dublin, Not set
Assuta Ashdod Medical Center ( Site 1703), Ashdod, Not set
Soroka Medical Center-Oncology ( Site 1702), Be'er Sheva, Not set
Bnai Zion Medical Center-Oncology ( Site 1704), Haifa, Not set
Sheba Medical Center-ONCOLOGY ( Site 1700), Ramat Gan, Not set
Sourasky Medical Center-Oncology ( Site 1701), Tel Aviv, Not set
Fondazione Policlinico Universitario Agostino Gemelli-Medical Oncology ( Site 1113), Roma, Lazio
Ospedale San Raffaele-Oncologia Medica ( Site 1110), Milano, Lombardia
Ospedale San Gerardo-ASST Monza-Research Unit Phase 1 ( Site 1115), Monza, Lombardia
Humanitas-U.O di Oncologia medica ed Ematologia ( Site 1114), Rozzano, Milano
Instituto Tumori Giovanni Paolo II-ONCOLOGIA MEDICA ( Site 1112), Bari, Not set
Ospedale Cannizzaro ( Site 1118), Catania, Not set
Istituto Europeo di Oncologia IRCCS-Divisione di Senologia Medica ( Site 1111), Milano, Not set
Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 1116), Napoli, Not set
Istituto Oncologico Veneto IRCCS ( Site 1117), Padova, Not set
Hyogo Medical University Hospital ( Site 2201), Nishinomiya, Hyogo
St. Marianna University School of Medicine Hospital ( Site 2205), Kawasaki, Kanagawa
Kitasato University Hospital ( Site 2204), Sagamihara, Kanagawa
Osaka University Hospital ( Site 2211), Suita, Osaka
Saitama Medical University International Medical Center ( Site 2208), Hidaka-city, Saitama
Tokyo Medical University Hospital ( Site 2206), Shinjuku-ku, Tokyo
Chiba University Hospital ( Site 2212), Chiba, Not set
National Hospital Organization Kyushu Cancer Center ( Site 2209), Fukuoka, Not set
Fukushima Medical University ( Site 2200), Fukushima, Not set
Kumamoto University ( Site 2203), Kumamoto, Not set
St. Luke's International Hospital ( Site 2207), Tokyo, Not set
Juntendo University Hospital ( Site 2210), Tokyo, Not set
National Cancer Center-Center for Breast Cancer ( Site 2404), Goyang-si, Kyonggi-do
Seoul National University Bundang Hospital ( Site 2406), Seongnam, Kyonggi-do
Seoul National University Hospital-Internal Medicine ( Site 2403), Seoul, Not set
Severance Hospital, Yonsei University Health System ( Site 2400), Seoul, Not set
Asan Medical Center ( Site 2402), Seoul, Not set
Samsung Medical Center-Division of Hematology/Oncology ( Site 2401), Seoul, Not set
University Malaya Medical Centre ( Site 2505), Lembah Pantai, Kuala Lumpur
Hospital Pulau Pinang ( Site 2504), George Town, Pulau Pinang
Sarawak General Hospital-Radiotherapy Unit ( Site 2501), Kuching, Sarawak
Hospital Kuala Lumpur-Radiotherapy and Oncology ( Site 2506), Kuala Lumpur, Not set
Pantai Hospital Kuala Lumpur-Cancer Centre ( Site 2503), Kuala Lumpur, Not set
Samadhi Centro Oncológico ( Site 0258), México, Distrito Federal
Hospital Civil Fray Antonio Alcalde-Oncology ( Site 0262), Guadalajara, Jalisco
Filios Alta Medicina ( Site 0253), Monterrey, Nuevo Leon
Centro Estatal de Cancerologia-Investigación ( Site 0256), Chihuahua, Not set
Centro de Investigacion Clinica de Oaxaca ( Site 0252), Oaxaca, Not set
Radboudumc-Medical Oncology ( Site 1360), Nijmegen, Gelderland
Maastricht UMC+-Medical Oncology ( Site 1353), Maastricht, Limburg
Jeroen Bosch Hospital ( Site 1359), Den Bosch, Noord-Brabant
Elisabeth-TweeSteden Ziekenhuis-Internal Medicine ( Site 1357), Tilburg, Noord-Brabant
Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL) ( Site 1351), Amsterdam, Noord-Holland
Meander Medisch Centrum ( Site 1358), Amersfoort, Utrecht
Leids Universitair Medisch Centrum-Medical Oncology ( Site 1356), Leiden, Zuid-Holland
Haaglanden MC - locatie Antoniushove-Medical oncology ( Site 1355), Leidschendam, Zuid-Holland
Franciscus Gasthuis & Vlietland, Locatie Vlietland ( Site 1354), Schiedam, Zuid-Holland
East Avenue Medical Center ( Site 0802), Quezon City, National Capital Region
CARDINAL SANTOS MEDICAL CENTER-Research Room ( Site 0800), San Juan, National Capital Region
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1813), Bydgoszcz, Kujawsko-pomorskie
Pratia MCM Krakow ( Site 1809), Krakow, Malopolskie
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1818), Siedlce, Mazowieckie
Lux med onkologia sp. z o.o. ( Site 1808), Warsaw, Mazowieckie
Luxmed Onkologia sp. z o. o. ( Site 1820), Warszawa, Mazowieckie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworów Piersi i Chirurgii (, Warszawa, Mazowieckie
Wojskowy Instytut Medyczny-Klinika Onkologii ( Site 1803), Warszawa, Mazowieckie
Mazowiecki Szpital Onkologiczny-BREAST CANCER ( Site 1821), Wieliszew, Mazowieckie
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1819), Przemysl, Podkarpackie
Bialostockie Centrum Onkologii-Oddzial Onkologii Klinicznej ( Site 1812), Bialystok, Podlaskie
Narodowy Instytut Onkologii - Oddzial w Gliwicach-Breast Unit ( Site 1811), Gliwice, Slaskie
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 1815), Koszalin, Zachodniopomorskie
Champalimaud Foundation ( Site 1006), Lisbon, Lisboa
Centro Hospitalar Universitário Lisboa Norte, E.P.E. - Hospital de Santa Maria ( Site 1004), Lisbon, Lisboa
UNIDADE LOCAL DE SAUDE DE MATOSINHOS ( Site 1007), Matosinhos, Porto
Centro Hospitalar do Porto - Hospital de Santo António-Oncology Service ( Site 1003), Porto, Not set
Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 1005), Porto, Not set
Cardiomed SRL Cluj-Napoca ( Site 2902), Cluj-Napoca, Cluj
Institutul Oncologic-Day Hospital Unit ( Site 2905), Cluj-Napoca, Cluj
Centrul de Oncologie "Sfântul Nectarie"-Medical Oncology ( Site 2901), Craiova, Dolj
Oncopremium Team-Oncology ( Site 2903), Baia Mare, Maramures
Sigmedical Services SRL ( Site 2904), Suceava, Not set
Arkhangelsk Clinical Oncological Dispensary-Chemotherapy department ( Site 1902), Arkhangelsk, Arkhangel Skaya Oblast
Podolsk Regional Clinical Hospital ( Site 1907), Podolsk, Moskovskaya Oblast
Moscow Clinical Research Center-Chemotherapy department ( Site 1903), Moscow, Moskva
Fed State Budgetary Inst N.N. Blokhin Med Center of Oncology MHRF ( Site 1901), Moscow, Moskva
Central Clinical Hospital of the Presidential Administrative Department ( Site 1904), Moscow, Moskva
Nizhegorodsky Regional Oncology Dispensary-chemotherapy ( Site 1912), Nizhniy Novgorod, Nizhegorodskaya Oblast
Ryazan Regional Clinical Oncology Center-Oncology #1 ( Site 1906), Ryazan, Ryazanskaya Oblast
N.N.Petrov Research Institute of Oncology ( Site 1900), Saint Petersburg, Sankt-Peterburg
St. Petersburg Clinical Hospital of Russian Academy Of Sciences-Medical Oncology ( Site 1905), St. Petersburg, Sankt-Peterburg
Hospital Quiron Barcelona ( Site 1326), Barcelona, Cataluna
HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON ( Site 1333), Madrid, Madrid, Comunidad De
Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 1320), Madrid, Madrid, Comunidad De
HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID-ONCOLOGIA MEDICA ( Site 1323), Pozuelo de Alarcon, Madrid
Fundación Instituto Valenciano de Oncología-Oncologico ( Site 1332), Valencia, Valenciana, Comunitat
Karolinska Universitetssjukhuset Solna-Tema Cancer - ME Bröst- endokrina tumörer och sarkom ( Site 1, Stockholm, Stockholms Lan
Södra Älvsborg Sjukhus ( Site 1406), Borås, Vastra Gotalands Lan
Ege University Medicine of Faculty ( Site 2004), Bornova, Izmir
I.E.U. Medical Point Hastanesi-Oncology ( Site 2016), Izmir, Karsiyaka, Izmir
Baskent University Dr. Turgut Noyan Research and Training Center ( Site 2013), Adana, Not set
Hacettepe Universitesi-oncology hospital ( Site 2000), Ankara, Not set
Memorial Ankara Hastanesi-Medical Oncology ( Site 2002), Ankara, Not set
Gazi Universitesi-Oncology ( Site 2010), Ankara, Not set
ANKARA ŞEHİR HASTANESİ-Medical Oncology ( Site 2014), Ankara, Not set
Akdeniz Universitesi Hastanesi-Medical Oncology ( Site 2009), Antalya, Not set
Istanbul Universitesi Cerrahpasa-Medical Oncology ( Site 2012), Istanbul, Not set
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 2005), Istanbul, Not set
İnönü Üniversitesi Turgut Özal Tıp Merkezi Eğitim ve Araştırma Hastanesi-Medical Oncology Department, Malatya, Not set
The Royal Cornwall Hospital ( Site 1507), Truro, Cornwall
Leicester Royal Infirmary-HOPE Clinical Trials Unit ( Site 1502), Leicester, England
St Bartholomew's Hospital ( Site 1508), London, England
The Christie ( Site 1510), Manchester, England
Blackpool Victoria Hospital ( Site 1503), Blackpool, Lancashire
North West Cancer Centre ( Site 1511), Londonderry, London, City Of
Guy's & St Thomas' NHS Foundation Trust ( Site 1501), London, London, City Of
Conditions: Breast Neoplasms
A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection, 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer, Compared to Nab-paclitaxel+Gemcitabine Treatment
Completed
The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for cancer therapy, namely 5 fluorouracil/leucovorin (5FU/LV) plus oxaliplatin compared to nab-paclitaxel + gemcitabine treatment in improving the overall survival of patients not previously treated for metastatic pancreatic cancer.
The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for cancer therapy, namely 5 fluorouracil/leucovorin (5FU/LV) plus oxaliplatin compared to nab-paclitaxel + gemcitabine treatment in improving the overall survival of patients not previously treated for metastatic pancreatic cancer. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +199 locations
University of Alabama at Birmingham, Birmingham, Alabama
Banner Health- MD Anderson Cancer Center, Gilbert, Arizona
Mayo Clinic - Scottsdale, Phoenix, Arizona
Comprehensive Blood And Cancer Center, Bakersfield, California
University of California- Irvine Health Cancer Cente, Costa Mesa, California
City of Hope National Medical Center, Duarte, California
University of California, Los Angeles (UCLA), Los Angeles, California
St. Jude Hospital Yorba Linda dba St. Joseph Heritage Healthcare, Orange, California
University of California - Irvine Medical Center, Orange, California
Torrance Memorial Physician Network Cancer Care, Redondo Beach, California
Sutter Health Sacramento, Sacramento, California
Presbyterian Intercommunity Hospital (PIH), Whittier, California
UC Health Memorial Hospital, Colorado Springs, Colorado
Rocky Mountain Cancer Center, Denver, Colorado
Mount Sinai Medical Center of Florida, Inc., Miami Beach, Florida
Miami Cancer Institute, Miami, Florida
Florida Cancer Specialists - Fort Myers, Sarasota, Florida
Florida Cancer Specialists - Panhandle, Tallahassee, Florida
Florida Cancer Specialists - St. Petersburg, Tampa, Florida
Florida Cancer Specialists - East, West Palm Beach, Florida
Rush University Medical Center, Chicago, Illinois
Edward Hospital - Elmhurst, Elmhurst, Illinois
Illinois CancerCare - Peoria, Peoria, Illinois
Carle Cancer Center, Urbana, Illinois
Fort Wayne Medical Oncology and Hematology, Fort Wayne, Indiana
Siouxland Hematology - Oncology Associates, LLP, Sioux City, Iowa
University of Kentucky Markey Cancer Center, Lexington, Kentucky
Pikeville Medical Center, Pikeville, Kentucky
Hematology Oncology Clinic, Baton Rouge, Louisiana
Ochsner Clinic Foundation, New Orleans, Louisiana
Willis-Knighton Cancer Center, Shreveport, Louisiana
Maine Center for Cancer Medicine, Scarborough, Maine
Maryland Oncology Hematology, Silver Spring, Maryland
Beth Israel Deaconess, Boston, Massachusetts
Henry Ford Health System, Detroit, Michigan
Cancer and Hematology Centers of Western Michigan, Grand Rapids, Michigan
Health Partners Institute, Minneapolis, Minnesota
Mayo Clinic - Rochester, Rochester, Minnesota
Research Medical Center, Kansas City, Missouri
Frontier Cancer Center, Billings, Montana
Oncology Hematology West P.C. dba Nebraska Cancer Specialists, Omaha, Nebraska
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada
Clinical Research Alliance, Inc, Lake Success, New York
David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York, New York
University of Rochester, Rochester, New York
Stony Brook University Medical Center, Stony Brook, New York
Messino Cancer Center, Asheville, North Carolina
The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solovev Research Institute (OSUCCC - James), Columbus, Ohio
Toledo Clinic Cancer Center, Toledo, Ohio
University of Oklahoma - Health Sciences Center, Oklahoma City, Oklahoma
Oncology Associates of Oregon, Eugene, Oregon
Compass Oncology - Rose Quarter Cancer Center, Portland, Oregon
Kaiser Permanente - Northwest, Portland, Oregon
Oregon Health & Science University (OHSU), Portland, Oregon
University of Pittsburgh Medical Center (UPMC) - Hillman Cancer Center, Pittsburgh, Pennsylvania
Greenville Hospital System, Greenville, South Carolina
Chattanooga Oncology Hematology Care - Tennessee Oncology, Chattanooga, Tennessee
The West Cancer Center, Memphis, Tennessee
Sarah Cannon and HCA Research Institute, Nashville, Tennessee
Texas Oncology - Austin, Austin, Texas
Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas, Texas
The Center for Cancer and Blood Disorders, Fort Worth, Texas
Baylor College of Medicine, Houston, Texas
Houston Methodist Research Institute, Houston, Texas
MD Anderson Cancer Center, Houston, Texas
Oncology Consultants, Houston, Texas
Texas Oncology - Tyler, Tyler, Texas
Texas Oncology - Wichita Falls, Wichita Falls, Texas
Utah Cancer Specialists, Salt Lake City, Utah
Virginia Cancer Specialists, Fairfax, Virginia
Blue Ridge Cancer Care, Wytheville, Virginia
Froedtert Hospital and the Medical College of Wisconsin, Milwaukee, Wisconsin
Bankstown-Lidcombe Hospital, Bankstown, Not set
Monash Medical Centre, Clayton, Not set
Fiona Stanley Hospital, Murdoch, Not set
Sir Charles Gairdner Hospital, Nedlands, Not set
St John of God Subiaco Hospital, Subiaco, Not set
Queen Elizabeth Hospital, Woodville South, Not set
Medizinische Universitaet Graz, Graz, Not set
Ordensklinikum Linz GmbH Barmherzige Schwestern, Linz, Not set
SCRI-CCCIT Gemeinnutzige Gmbh- Gemeinnutzige Salzburger Landeskliniken Betriebsgesmbh, Salzburg, Not set
Medical University of Vienna, Vienna, Not set
Onze-Lieve-Vrouwziekenhuis, Aalst, Not set
ASBL Grand Hôpital de Charleroi (GHdC), Site Notre Dame, Charleroi, Not set
Universitair Ziekenhuis Antwerpen (UZA), Edegem, Not set
University Hospital Gent, Gent, Not set
Hospital centre Jolimont, Haine-Saint-Paul, Not set
University Hospital (UZ) Leuven, Leuven, Not set
University Hospital Mont-Godinne, Yvoir, Not set
Fundação Pio XII - Hospital de Câncer de Barretos, Barretos, Not set
Centro Regional Integrado de Oncologia (CRIO), Ceara, Not set
Instituto de Oncologia do Parana - IOP, Curitiba, Not set
Centro de Pesquisas Oncológicas - CEPON, Florianópolis, Not set
Hospital de Caridade de Ijui, Ijuí, Not set
Clinica Neoplasias Litoral, Itajaí, Not set
Hospital Bruno Born, Lajeado, Not set
Centro de Pesquisas Clinicas de Natal - CPCLIN, Natal, Not set
Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Not set
Instituto Nacional Do Cancer (INCA), Rio de Janeiro, Not set
Instituto COI, Rio De Janeiro, Not set
Instituto Brasileiro de Controle do Cancer - IBCC (Sao Paulo), San Paolo, Not set
CIP Centro Integrado de Pesquisas do Hospital de Base, São José Do Rio Preto, Not set
Hospital Alemão Oswaldo Cruz, São Paulo, Not set
Instituto do Cancer do Estado de São Paulo (ICESP), São Paulo, Not set
Alberta Health Services Cross Cancer Institute, Edmonton, Not set
Queen Elizabeth II Health Sciences Centre, Halifax, Not set
McGill University Faculty of Medicine - Royal Victoria Hospital, Montréal, Not set
Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Not set
Masarykuv onkologicky ustav, Brno, Not set
Fakultni nemocnice Hradec Kralove, Hradec Králové, Not set
University Hospital Olomouc, Department of Oncology, Olomouc, Not set
Thomayerova Nemocnice, Praha, Not set
CHRU de Tours - Hôpital Trousseau, Chambray-lès-Tours, Not set
Centre Oscar Lambret, Lille, Not set
Hôpital Edouard Herriot, Lyon, Not set
Centre Leon Berard, Lyon, Not set
Hopital Prive Jean Mermoz, Lyon, Not set
Centre Antoine-Lacassagne, Nice, Not set
Hopital Saint Louis, Paris, Not set
CHU Bordeaux - Hopital Haut-Leveque, Pessac, Not set
Centre Hospitalier Universitaire de Poitiers - Poitiers University Hospital, Poitiers Cedex, Not set
Strasbourg Oncologie Liberale, Strasbourg, Not set
Charité - Universitaetsmedizin Berlin, Berlin, Not set
St. Josef-Hospital, Bochum, Not set
Klinikum Esslingen GmbH, Esslingen, Not set
Krankenhaus Nordwest, Frankfurt, Not set
Studiengesellschaft BSF, Halle, Not set
Martin Luther Universitat Halle-Wittenberg, Halle, Not set
Facharztzentrum Eppendorf, Hamburg, Not set
Marienkrankenhaus Hamburg, Hamburg, Not set
Asklepios Klinik Altona, Hamburg, Not set
Medizinische Hochschule Hannover, Hannover, Not set
Slk-Kliniken, Heilbronn, Not set
Klinikum Mannheim, Mannheim, Not set
Krankenhaus St. Franziskus - Kliniken Maria Hilf GmbH, Mönchengladbach, Not set
Universitaetsklinikum Tuebingen, Tuebingen, Not set
Universitaetsklinikum Ulm, Ulm, Not set
Agios Savvas Anticancer Hospital, Athens, Not set
General Hospital of Athens - Laiko, Athens, Not set
National and Kapodistrian University of Athens, Athens, Not set
University General Hospital of Ioannina, Ioánnina, Not set
Theagenion Hospital, Thessaloníki, Not set
Dél-pesti Centrumkórház - Szent László Kórház telephely, Budapest, Not set
Országos Onkológiai Intézet, Budapest, Not set
Semmelweis Egyetem Belgyógyászati és Hematológiai Klinika, Budapest, Not set
Debreceni Egyetem Klinikai Kozpont, Debrecen, Not set
Somogy Megyei Kaposi Mor Oktato Korhaz, Kaposvár, Not set
Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház-Rendelointézet, Szolnok, Not set
Soroka Medical Center, Beer Sheva, Not set
Rambam Health Care Campus, Haifa, Not set
Policlinico S. Orsola-Malpighi, Bologna, Not set
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori, Meldola, Not set
Istituto Europeo di Oncologia, Milano, Not set
Azienda Ospedaliero-Universitaria di Modena, Modena, Not set
AUSL di Piacenza-Ospedale Guglielmo Da Saliceto, Piacenza, Not set
Azienda Ospedaliero Universitaria Pisana, Pisa, Not set
AOU Ospedali Riuniti di Ancona, Torrette, Not set
Azienda Ospedaliera - Universitaria Integrata di Verona - Ospedale Borgo Roma, Verona, Not set
Inje University Haeundae Paik Hospital, Busan, Not set
National Cancer Center, Goyang-si, Not set
CHA Bundang Medical Center, Gyeonggi-do, Not set
Asan Medical Center, Seoul, Not set
Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
Hospital de Braga, Braga, Not set
Centro Hospitalar Universitario de Lisboa Norte - Hospital de Santa Maria, Lisboa, Not set
Champalimaud Cancer Center, Lisbon, Not set
Unidade Local de Saude Matosinhos E.P.E. Hospital Pedro Hispano, Senhora da Hora, Not set
Centro Hospitalar de Vila Nova de Gaia/Espinho EPE, Vila Nova de Gaia, Not set
Evimed LLC, Chelyabinsk, Not set
Limited Liability Company- Clinica Druzhkovyh, Kazan, Not set
Kursk Regional Clinical Oncology Dispensary, Kursk, Not set
Main Military Clinical Hospital named after N.N. Burdenko, Moscow, Not set
Volga District Medical Centre, Novgorod, Not set
Federal State Budgetary Institution - Russian Scientific Center of Radiology and Surgical Technologies n.a. academician A.M.Granov, Saint-Petersburg, Not set
Hospital General Universitario de Elche, Alicante, Not set
Hospital Universitario de Badajoz, Badajoz, Not set
Hospital Germans Trias i Pujol, Badalona, Not set
Hospital Quironsalud Barcelona, Barcelona, Not set
Hospital de la Santa Creu i Sant Pau Barcelona, Barcelona, Not set
Hospital Vall D Hebron, Barcelona, Not set
Hospital Clinic Barcelona, Barcelona, Not set
Corporacio Sanitaria Parc Tauli - Hospital de Sabadell, Barcelona, Not set
Institut Catala d'Oncologia - L'Hospitalet, Barcelona, Not set
Complejo Hospitalario Universitario de Granada - Hospital Universitario Virgen de las Nieves, Granada, Not set
Hospital General Universitario Gregorio Marañon, Madrid, Not set
Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Centro Integral Oncologico Clara Campal, Madrid, Not set
Hospital Regional Universitario de Malaga, Málaga, Not set
Complejo Hospitalario de Navarra, Pamplona, Not set
Hospital Universitario Marques de Valdecilla, Santander, Not set
Hospital Universitario Miguel Servet, Zaragoza, Not set
Guy's and St. Thomas' NHS Foundation Trust, London, Not set
Royal Marsden Foundation Trust, London, Not set
Royal Marsden Foundation Trust, London, Not set
Imperial College Healthcare NHS Trust, London, Not set
Cancer Research UK - Christie Hospital Foundation NHS Trust - Dept of Medical Oncology, Manchester, Not set
Nottingham City Hospital, Nottingham, Not set
Conditions: Metastatic Adenocarcinoma of the Pancreas
Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Versus Chemotherapy for Endometrial Carcinoma (ENGOT-en9 / MK-7902-001)
Completed
The purpose of this study is to compare the efficacy of pembrolizumab + lenvatinib to chemotherapy in female participants with Stage III, IV, or recurrent endometrial carcinoma. It is hypothesized that the combination of pembrolizumab + lenvatinib will be superior to chemotherapy for progression-free survival (PFS) per Response Evaluation Criteria In Solid Tumors version 1.1 (RECIST 1.1) by blinded independent central review (BICR). It is also hypothesized that the combination of pembrolizumab +... Read More
The purpose of this study is to compare the efficacy of pembrolizumab + lenvatinib to chemotherapy in female participants with Stage III, IV, or recurrent endometrial carcinoma. It is hypothesized that the combination of pembrolizumab + lenvatinib will be superior to chemotherapy for progression-free survival (PFS) per Response Evaluation Criteria In Solid Tumors version 1.1 (RECIST 1.1) by blinded independent central review (BICR). It is also hypothesized that the combination of pembrolizumab + lenvatinib will be superior to chemotherapy for overall survival (OS).
As of Amendment 7 eligible participants on study completion will be able to transition to an extension study, if available, in which they can continue to receive pembrolizumab monotherapy, lenvatinib monotherapy, or a combination of both pembrolizumab and lenvatinib as received in the parent study. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: University of South Alabama, Mitchell Cancer Institute ( Site 0245), Mobile, Alabama +194 locations
University of South Alabama, Mitchell Cancer Institute ( Site 0245), Mobile, Alabama
Arizona Oncology Associates PC- HOPE ( Site 8005), Tucson, Arizona
UCLA Hematology and Oncology Clinic (Westwood) ( Site 0233), Los Angeles, California
University of Colorado Cancer Center ( Site 0204), Aurora, Colorado
Smilow Cancer Hospital at Yale New Haven ( Site 0202), New Haven, Connecticut
University of Miami Health System ( Site 0249), Miami, Florida
Georgia Cancer Center at Augusta University ( Site 0222), Augusta, Georgia
Women's Cancer Care ( Site 0208), Covington, Louisiana
Maine Medical Partners ( Site 0217), Scarborough, Maine
Minnesota Oncology Hematology, PA ( Site 8003), Minneapolis, Minnesota
Memorial Sloan-Kettering Cancer Center At Basking Ridge ( Site 0268), Basking Ridge, New Jersey
John Theurer Cancer Center at Hackensack University Med Ctr ( Site 0226), Hackensack, New Jersey
Memorial Sloan Kettering Cancer Center- Monmouth ( Site 0273), Middletown, New Jersey
MSKCC-Bergen ( Site 0276), Montvale, New Jersey
Holy Name Medical Center ( Site 0235), Teaneck, New Jersey
Memorial Sloan-Kettering Cancer Center at Commack ( Site 0267), Commack, New York
Memorial Sloan Kettering Cancer Center - West Harrison ( Site 0274), Harrison, New York
The Blavatnik Family- Chelsea Medical Center at Mount Sinai ( Site 0206), New York, New York
Memorial Sloan Kettering Cancer Center ( Site 0246), New York, New York
University of Rochester ( Site 0238), Rochester, New York
Memorial Sloan Kettering Cancer Center - Nassau ( Site 0275), Uniondale, New York
University of North Carolina- Chapel Hill ( Site 0254), Chapel Hill, North Carolina
Roger Maris Cancer Center ( Site 0277), Fargo, North Dakota
Willamette Valley Cancer Institute and Research Center ( Site 8004), Eugene, Oregon
Sanford Cancer Center Oncology Clinic ( Site 0205), Sioux Falls, South Dakota
Parkland Health & Hospital System ( Site 0272), Dallas, Texas
University of Texas Southwestern Medical Center ( Site 0264), Dallas, Texas
Texas Oncology-The Woodlands ( Site 8000), The Woodlands, Texas
Legacy Salmon Creek Medical Center ( Site 0253), Vancouver, Washington
IDIM Instituto de Diagnostico e Investigaciones Metabolicas ( Site 2607), Caba, Buenos Aires
Hospital Italiano de La Plata ( Site 2601), La Plata, Buenos Aires
Instituto de Investigaciones Clinicas Mar del Plata ( Site 2606), Mar del Plata, Buenos Aires
Hospital Aleman ( Site 2600), Buenos Aires, Not set
Hospital Italiano de Buenos Aires ( Site 2603), Buenos Aires, Not set
Centro Oncologico Riojano Integral ( Site 2605), La Rioja, Not set
Chris OBrien Lifehouse ( Site 1605), Camperdown, New South Wales
Prince of Wales Hospital [Australia] ( Site 1603), Randwick, New South Wales
Royal North Shore Hospital ( Site 1600), St Leonards, New South Wales
The Crown Princess Mary Cancer Centre - Westmead Hospital ( Site 1602), Westmead, New South Wales
Mater Misericordiae Ltd ( Site 1608), South Brisbane, Queensland
Monash Health ( Site 1606), Clayton, Victoria
Epworth Freemasons Hospital ( Site 1609), Melbourne, Victoria
Sir Charles Gairdner Hospital ( Site 1604), Nedlands, Western Australia
Universitatsklinik fuer Frauenheilkunde und Geburtshilfe ( Site 3301), Graz, Steiermark
Medizinische Universitat Innsbruck ( Site 3302), Innsbruck, Tirol
Medizinische Universitat Wien ( Site 3300), Vienna, Wien
UZA University Hospital Antwerp ( Site 3204), Edegem, Antwerpen
UZ Leuven ( Site 3200), Leuven, Antwerpen
Cliniques Universitaires Saint-Luc ( Site 3203), Brussels, Bruxelles-Capitale, Region De
AZ Maria Middelares Gent ( Site 3202), Gent, Oost-Vlaanderen
AZ Delta ( Site 3206), Roeselare, West-Vlaanderen
Instituto do Cancer do Ceara ( Site 2703), Fortaleza, Ceara
Hospital Araujo Jorge Associacao de Combate ao Cancer de Goias ( Site 2702), Goiania, Goias
Faculdade de Medicina da Universidade Federal de Minas Gerais ( Site 2708), Belo Horizonte, Minas Gerais
Hospital de Caridade de Ijui ( Site 2712), Ijui, Rio Grande Do Sul
Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da Pucrs ( Site 2701), Porto Alegre, Rio Grande Do Sul
Hospital de Base de Sao Jose de Rio Preto ( Site 2704), Sao Jose do Rio Preto, Sao Paulo
Instituto Nacional do Cancer II ( Site 2707), Rio de Janeiro, Not set
Clinica de Pesquisas e Ctro de Estudos Onc. Ginecol. e Mamaria Ltda ( Site 2706), Sao Paulo, Not set
Real e Benemerita Associacao Portuguesa de Beneficencia ( Site 2713), Sao Paulo, Not set
A.C. Camargo Cancer Center ( Site 2705), Sao Paulo, Not set
Cross Cancer Institute ( Site 0408), Edmonton, Alberta
BC Cancer-Kelowna - Sindi Ahluwalia Hawkins Centre ( Site 0402), Kelowna, British Columbia
BC Cancer-Vancouver Center ( Site 0412), Vancouver, British Columbia
Juravinski Cancer Centre ( Site 0406), Hamilton, Ontario
Kingston Health Sciences Centre ( Site 0401), Kingston, Ontario
The Credit Valley Hospital ( Site 0403), Mississauga, Ontario
Sunnybrook Research Institute ( Site 0410), Toronto, Ontario
Princess Margaret Cancer Centre ( Site 0409), Toronto, Ontario
CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont ( Site 0414), Montreal, Quebec
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0411), Montreal, Quebec
McGill University Health Centre ( Site 0404), Montreal, Quebec
CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 0417), Sherbrooke, Quebec
Anhui Provincial Cancer Hospital ( Site 2509), Hefei, Anhui
Beijing Obstetrics and Gynecology Hospital Capital Medical University ( Site 2505), Beijing, Beijing
Peking Union Medical College Hospital ( Site 2501), Beijing, Beijing
Beijing Cancer Hospital ( Site 2504), Beijing, Beijing
Chongqing Cancer Hospital ( Site 2513), Chongqing, Chongqing
The First Affiliated Hospital.Sun Yat-sen University ( Site 2507), Guangzhou, Guangdong
Guang Xi Tumour Hospital, Department of Chemotherapy ( Site 2517), Nanning, Guangxi
Hubei Cancer Hospital ( Site 2510), Wuhan, Hubei
Xiangya Hospital Central-South University ( Site 2512), Changsha, Hunan
Nanjing Maternity and Child Health Care Hospital ( Site 2508), Nanjing, Jiangsu
The first affiliated Hospital of Xi an Jiaotong University ( Site 2502), XI An, Shaanxi
Fudan University Shanghai Cancer Center ( Site 2500), Shanghai, Shanghai
Obstetrics and Gynecology Hosp. Fudan University ( Site 2503), Shanghai, Shanghai
The First Affiliated Hospital of Xinjiang Medical University ( Site 2515), Urumqi, Xinjiang
Women s Hospital School of Medicine Zhejiang University ( Site 2511), Hangzhou, Zhejiang
Zhejiang Cancer Hospital ( Site 2506), Hangzhou, Zhejiang
Universitaetsmedizin Mannheim. Klinik fuer Kinder und Jugendmedizin ( Site 0622), Mannheim, Baden-Wurttemberg
Universitaetsklinikum Muenster ( Site 0615), Muenster, Baden-Wurttemberg
Caritas-Krankenhaus St. Josef Regensburg ( Site 0613), Regensburg, Bayern
HELIOS Dr. Horst Schmidt Kliniken Wiesbaden ( Site 0623), Wiesbaden, Hessen
Universitaetsklinikum Essen ( Site 0616), Essen, Nordrhein-Westfalen
Universitaetsklinikum Jena ( Site 0612), Jena, Thuringen
Charite Universitaetsmedizin Berlin ( Site 0609), Berlin, Not set
Cork University Hospital ( Site 1400), Cork, Not set
St James Hospital ( Site 1401), Dublin, Not set
Meir Medical Center ( Site 0702), Kfar-Saba, Central
Edith Wolfson Medical Center ( Site 0703), Holon, Tell Abib
Rambam Medical Center ( Site 0700), Haifa, Not set
Chaim Sheba Medical Center ( Site 0707), Ramat Gan, Not set
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori ( Site 0800), Meldola, Emilia-Romagna
Policlinico Universitario Agostino Gemelli ( Site 0805), Rome, Roma
Ospedale dell Angelo ( Site 0810), Mestre, Venezia
Medical Oncology Ospedale San Donato ( Site 0812), Arezzo, Not set
IRCCS Giovanni Paolo II. Ospedale Oncologico ( Site 0801), Bari, Not set
Ospedale Policlinico S. Orsola-Malpighi ( Site 0803), Bologna, Not set
Ospedale Antonio Perrino ( Site 0806), Brindisi, Not set
Azienda Ospedaliera per l Emergenza Cannizzaro ( Site 0807), Catania, Not set
Istituto Nazionale Tumori Fondazione Pascale ( Site 0808), Napoli, Not set
Ehime University Hospital ( Site 2413), Toon, Ehime
Kurume University Hospital ( Site 2403), Kurume, Fukuoka
Gunma Prefectural Cancer Center ( Site 2404), Ota, Gunma
National Hospital Organization Hokkaido Cancer Center ( Site 2408), Sapporo, Hokkaido
Hyogo Cancer Center ( Site 2414), Akashi, Hyogo
Nippon Medical School Musashi Kosugi Hospital ( Site 2417), Kawasaki, Kanagawa
St. Marianna University School of Medicine Hospital ( Site 2416), Kawasaki, Kanagawa
University of the Ryukyus Hospital ( Site 2412), Nakagami-gun, Okinawa
Saitama Medical University International Medical Center ( Site 2410), Hidaka, Saitama
Saitama Cancer Center ( Site 2406), Kitaadachi-gun, Saitama
National Defense Medical College Hospital ( Site 2418), Tokorozawa, Saitama
Kyorin University Hospital ( Site 2402), Mitaka, Tokyo
National Hospital Organization Kyushu Cancer Center ( Site 2405), Fukuoka, Not set
Niigata Cancer Center Hospital ( Site 2415), Niigata, Not set
Osaka International Cancer Institute ( Site 2409), Osaka, Not set
The Cancer Institute Hospital of JFCR ( Site 2401), Tokyo, Not set
Showa University Hospital ( Site 2419), Tokyo, Not set
Keio University Hospital ( Site 2411), Tokyo, Not set
Seoul National University Bundang Hospital ( Site 1802), Seongnam-si, Kyonggi-do
Seoul National University Hospital ( Site 1801), Seoul, Not set
Severance Hospital Yonsei University Health System ( Site 1804), Seoul, Not set
Asan Medical Center ( Site 1800), Seoul, Not set
Samsung Medical Center ( Site 1803), Seoul, Not set
Hospital San Lucas Cardiologica del Sureste ( Site 3103), Tuxtla Gutierrez, Chiapas
I CAN Oncology SA de SV ( Site 3102), Monterrey, Nuevo Leon
Centro Estatal de Cancerologia de Chihuahua ( Site 3101), Chihuahua, Not set
Consultorio Dentro de la Torre Medica Dalinde Oncologia Medica ( Site 3108), Ciudad de Mexico, Not set
Centro de Investigacion Clinica Gramel ( Site 3107), Mexico City, Not set
Centro Oncologico Internacional. SEDNA ( Site 3106), Mexico City, Not set
Samodzielny Publiczny Szpital Kliniczny Nr 1 w Lublinie ( Site 1008), Lublin, Dolnoslaskie
Instytut Centrum Zdrowia Matki Polki ( Site 1020), Lodz, Lodzkie
Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie ( Site 1019), Krakow, Malopolskie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 1009), Warsaw, Mazowieckie
Szpital Kliniczny im Ks Anny Mazowieckiej ( Site 1011), Warszawa, Mazowieckie
Bialostockie Centrum Onkologii ( Site 1005), Bialystok, Podlaskie
Centrum Onkologii Instytut im. MSC Oddział w Gliwicach ( Site 1017), Gliwice, Slaskie
Wielkopolskie Centrum Onkologii im.M.Sklodowskiej-Curie ( Site 1004), Poznan, Wielkopolskie
Krasnoyarsk Regional Clinical oncology dispensary ( Site 1118), Krasnoyarsk, Krasnoyarskiy Kray
Russian Oncological Research Center n.a. N.N.Blokhin of MoH ( Site 1100), Moscow, Moskva
FSBI-FRCC of Special Types Med. Care and Technologies FMBA of Russia ( Site 1102), Moscow, Moskva
Medical Rehabilitation Center ( Site 1101), Moscow, Moskva
Samara Regional Clinical Oncology Center ( Site 1117), Samara, Samarskaya Oblast
St.Petersburg Clinical Hospital RAS ( Site 1124), Saint Petersburg, Sankt-Peterburg
SPb SBHI City Clinical Oncological Dispensary ( Site 1104), Saint Petersburg, Sankt-Peterburg
Railway Hospital of OJSC ( Site 1122), Saint-Petersburg, Sankt-Peterburg
National Medical Research Center of Oncology N.A. N.N. Petrov ( Site 1103), Saint-Petersburg, Sankt-Peterburg
Republican Clinical Oncology Dispensary of Tatarstan MoH ( Site 1108), Kazan, Tatarstan, Respublika
Siberian State Medical University ( Site 1121), Tomsk, Tomskaya Oblast
Institut Catala d Oncologia Badalona ( Site 1201), Badalona, Barcelona
Complejo Hospitalario Universitario A Coruna. CHUAC ( Site 1202), A Coruna, La Coruna
Instituto Valenciano de Oncologia - IVO ( Site 1205), Valencia, Valenciana, Comunitat
Hospital General Universitario de Valencia ( Site 1203), Valencia, Valenciana, Comunitat
Parc de Salut Mar ( Site 1200), Barcelona, Not set
Hospital Universitario Reina Sofia ( Site 1207), Cordoba, Not set
Hospital Clinico San Carlos ( Site 1209), Madrid, Not set
Hospital Materno Infantil [Malaga, Spain] ( Site 1208), Malaga, Not set
China Medical University Hospital ( Site 1903), Taichung, Not set
Taichung Veterans General Hospital ( Site 1902), Taichung, Not set
National Taiwan University Hospital ( Site 1904), Taipei, Not set
Taipei Veterans General Hospital ( Site 1900), Taipei, Not set
Linkou Chang Gung Memorial Hospital ( Site 1901), Taoyuan, Not set
Baskent Universitesi Adana Uygulama ve Arastirma Hastanesi ( Site 1303), Adana, Not set
Cukurova Uni. Tip Fakultesi ( Site 1302), Adana, Not set
Gazi Universitesi Tip Fakultesi ( Site 1308), Ankara, Not set
Baskent Universitesi Ankara Hastanesi ( Site 1300), Ankara, Not set
Akdeniz Universitesi Tıp Fakultesi ( Site 1301), Antalya, Not set
Uludag Universitesi Tip Fakultesi ( Site 1307), Bursa, Not set
Clinical oncology dispensary of Dnipro ( Site 1512), Dnipro, Dnipropetrovska Oblast
City Clinical Hosp.4 of DCC ( Site 1501), Dnipro, Dnipropetrovska Oblast
MI Precarpathian Clinical Oncology Center ( Site 1503), Ivano-Frankivsk, Ivano-Frankivska Oblast
Grigoriev Institute for medical Radiology NAMS of Ukraine ( Site 1511), Kharkiv, Kharkivska Oblast
Communal non profit enterprise Regional Clinical Oncology Center ( Site 1509), Kharkiv, Kharkivska Oblast
Khmelnitskiy Regional Onkology Dispensary ( Site 1513), Khmelnitskiy, Khmelnytska Oblast
Medical Center Asklepion LLC ( Site 1514), Khodosivka, Kyivska Oblast
National Cancer Institute of the MoH of Ukraine ( Site 1510), Kyiv, Kyivska Oblast
Medical and Diagnostic Centre LLC Dobryi Prognoz ( Site 1507), Kyiv, Kyivska Oblast
MI Odessa Regional Oncological Centre ( Site 1504), Odesa, Odeska Oblast
Kyiv City Clinical Oncology Centre ( Site 1505), Kyiv, Not set
Western General Hospital ( Site 1411), Edinburgh, Edinburgh, City Of
UCLH NHS Foundation Trust ( Site 1405), London, London, City Of
Mount Vernon Cancer Centre ( Site 1409), Northwood, London, City Of
Churchill Hospital ( Site 1406), Oxford, Oxfordshire
The James Cook University Hospital ( Site 1403), Middlesbrough, Not set
Northern Centre for Cancer Care ( Site 1408), Newcastle Upon Tyne, Not set
Conditions: Endometrial Neoplasms
A Phase 3 Randomized, Placebo-controlled Trial of Carboplatin and Paclitaxel With or Without Veliparib (ABT-888) in HER2-negative Metastatic or Locally Advanced Unresectable BRCA-associated Breast Cancer
Completed
The primary objective of the study is to assess the progression-free survival (PFS) of veliparib in combination with carboplatin and paclitaxel (C/P) compared to placebo plus C/P in participants with a Breast Cancer Gene 1 or 2 (BRCA1; BRCA2) mutation in Human Epidermal Growth Factor Receptor 2 (HER2)-negative metastatic or locally advanced unresectable breast cancer. The secondary objectives of the study are to assess overall survival (OS), clinical benefit rate (CBR) through the end of Week 24... Read More
The primary objective of the study is to assess the progression-free survival (PFS) of veliparib in combination with carboplatin and paclitaxel (C/P) compared to placebo plus C/P in participants with a Breast Cancer Gene 1 or 2 (BRCA1; BRCA2) mutation in Human Epidermal Growth Factor Receptor 2 (HER2)-negative metastatic or locally advanced unresectable breast cancer. The secondary objectives of the study are to assess overall survival (OS), clinical benefit rate (CBR) through the end of Week 24, objective response rate (ORR) and PFS on subsequent therapy (PFS2) in participants treated with veliparib in combination with C/P versus placebo in combination with C/P. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Banner MD Anderson Cancer Ctr /ID# 125011, Gilbert, Arizona +218 locations
Banner MD Anderson Cancer Ctr /ID# 125011, Gilbert, Arizona
University of Arkansas for Medical Sciences /ID# 124992, Little Rock, Arkansas
City of Hope /ID# 127117, Duarte, California
California Cancer Associates for Research & Excellence (cCARE) /ID# 136078, Fresno, California
Moores Cancer Center at UC San Diego /ID# 124991, La Jolla, California
Hematology and Oncology Assoc /ID# 130058, Newport Beach, California
Cancer Research Collaboration /ID# 128860, Santa Ana, California
Icri /Id# 128520, Whittier, California
Univ of Colorado Cancer Center /ID# 124983, Aurora, Colorado
Saint Joseph Hospital /ID# 131768, Denver, Colorado
Norwalk Hospital /ID# 133509, Norwalk, Connecticut
Lynn Cancer Institute, Boca /ID# 125013, Boca Raton, Florida
Holy Cross Hospital /ID# 125012, Fort Lauderdale, Florida
Sacred Heart Hospital /ID# 128279, Pensacola, Florida
Moffitt Cancer Center /ID# 124990, Tampa, Florida
Florida Cancer Specialists - East /ID# 125007, West Palm Beach, Florida
Emory Midtown Infectious Disease Clinic /ID# 133192, Atlanta, Georgia
The Cancer Ctr at DeKalb Med C /ID# 125024, Decatur, Georgia
University of Illinois - Chicago /ID# 127576, Chicago, Illinois
NorthShore University HealthSystem /ID# 124996, Evanston, Illinois
Midwestern Regional CTC /ID# 124986, Zion, Illinois
McFarland Clinic, PC /ID# 129904, Ames, Iowa
Johns Hopkins University /ID# 125015, Baltimore, Maryland
Baystate Medical Center /ID# 139461, Springfield, Massachusetts
UMass Chan Medical School /ID# 129067, Worcester, Massachusetts
Henry Ford Health System /ID# 134497, Detroit, Michigan
Spectrum Health Medical Group /ID# 133568, Grand Rapids, Michigan
Spectrum Health Medical Group /ID# 148471, Grand Rapids, Michigan
William Beaumont Hospital /ID# 125019, Royal Oak, Michigan
Univ of Mississippi Med Ctr,US /ID# 131352, Jackson, Mississippi
St. Lukes Cancer Institute /ID# 125023, Kansas City, Missouri
Washington University-School of Medicine /ID# 127575, Saint Louis, Missouri
Nebraska Hematology Oncology /ID# 132711, Lincoln, Nebraska
Rutgers Cancer Institute of New Jersey /ID# 125017, New Brunswick, New Jersey
University of New Mexico /ID# 125349, Albuquerque, New Mexico
Beth Israel Medical Center /ID# 125001, New York, New York
Mount Sinai St. Luke's /ID# 125003, New York, New York
Mission Cancer Center /ID# 134248, Asheville, North Carolina
Duke Cancer Center /ID# 124999, Durham, North Carolina
The Ohio State University /ID# 125022, Columbus, Ohio
University of Toledo /ID# 134849, Toledo, Ohio
Oregon Health and Science University /ID# 134229, Portland, Oregon
Lehigh Valley Health Network /ID# 130059, Allentown, Pennsylvania
Lehigh Valley Hosp/Muhlenberg /ID# 130277, Bethlehem, Pennsylvania
Penn State University and Milton S. Hershey Medical Center /ID# 124997, Hershey, Pennsylvania
Allegheny General Hospital /ID# 135094, Pittsburgh, Pennsylvania
University of Pittsburgh MC /ID# 125005, Pittsburgh, Pennsylvania
Texas Health Physicians Group /ID# 137740, Arlington, Texas
University of Texas Southwestern Medical Center /ID# 124989, Dallas, Texas
University of Texas MD Anderson Cancer Center /ID# 125353, Houston, Texas
University of Vermont Medical Center /ID# 125350, Burlington, Vermont
Swedish Cancer Institute - Issaquah /ID# 131534, Issaquah, Washington
Swedish Cancer Institute - Edmonds /ID# 131549, Seattle, Washington
Swedish Medical Center /ID# 125021, Seattle, Washington
Swedish Cancer Insititute - Ballard /ID# 131548, Seattle, Washington
Northwest Medical Specialties - Tacoma /ID# 125344, Tacoma, Washington
COIBA Centro de Oncologia e Investigacion de Buenos Aires /ID# 124839, Berazategui, Buenos Aires
Clinica Pergamino /ID# 127158, Pergamino, Buenos Aires
Instituto de Oncoloia de Rosario /ID# 127157, Rosario, Santa Fe
Centro Oncologico Riojano Integral /ID# 127938, La Rioja, Not set
St George Hospital /ID# 129416, Kogarah, New South Wales
Duplicate_The Prince of Wales Hospital /ID# 124845, Randwick, New South Wales
Southern Medical Day Care Centre /ID# 124844, Wollongong, New South Wales
Townsville University Hospital /ID# 126731, Douglas, Queensland
Duplicate_Flinders Centre for Innovation /ID# 127535, Bedford Park, South Australia
Royal Hobart Hospital /ID# 124849, Hobart, Tasmania
The Royal Melbourne Hospital /ID# 124846, Parkville, Victoria
Hollywood Private Hospital /ID# 124843, Nedlands, Western Australia
Ordensklinikum Linz GmbH Elisabethinen /ID# 126185, Linz, Oberoesterreich
Medizinische Universitaet Graz /ID# 126450, Graz, Steiermark
Medizinische Universitaet Wien /ID# 126184, Vienna, Wien
Landeskrankenhaus Salzburg-Universitätsklinikum der PMU (LKH) /ID# 126449, Salzburg, Not set
Bobruysk Interdistrict Onco. /ID# 137729, Bobruisk, Not set
State Institution Republican Scientific Practical Center of Oncology and Medical /ID# 125223, Minsk, Not set
Duplicate_Mogilev Reg Clin Oncology Dis /ID# 137728, Mogilev, Not set
Vitebsk Regional Clinical Oncology Dispensary /ID# 125219, Vitebsk, Not set
Universitair Ziekenhuis Antwerpen /ID# 124977, Edegem, Antwerpen
UCL Saint-Luc /ID# 124976, Woluwe-Saint-Lambert, Bruxelles-Capitale
Grand Hôpital de Charleroi /ID# 124981, Charleroi, Hainaut
Universitair Ziekenhuis Leuven /ID# 124980, Leuven, Vlaams-Brabant
Duplicate_AZ St-Jan Brugge-Oostende AV /ID# 124975, Brugge, West-Vlaanderen
ZNA Middelheim /ID# 124978, Antwerp, Not set
CHU UCL Namur - Sainte Elisabeth /ID# 124979, Namur, Not set
Duplicate_Sunnybrook Health Sciences Ctr /ID# 124882, Toronto, Ontario
Duplicate_Jewish General Hospital /ID# 124880, Montreal, Quebec
CHUM - Notre-Dame Hospital /ID# 124879, Montréal, Quebec
Duplicate_CHUQ-Hospital St. Sacrement /ID# 124881, Quebec City, Quebec
Hospital Clinico Vina del Mar /ID# 130100, Vina Del Mar, Valparaíso
Hospital Clinico Vina del Mar /ID# 148502, Vina Del Mar, Valparaíso
Instituto Nacional del Cancer /ID# 129343, Santiago, Not set
ICOS - Inst Clinic Oncology /ID# 125236, Temuco, Not set
Hospital Pablo Tobon Uribe /ID# 126657, Medellín, Antioquia
Instituto Medico de Alta Tecnologia Oncomédica S.A /ID# 129211, Monteria, Cordoba
Administradora del Country_S.A-Clinica Del Country /ID# 125255, Bogota, Cundinamarca
Hospital Univ San Ignacio /ID# 126655, Bogota, Cundinamarca
Centro Medico Imbanaco de Cali /ID# 126656, Cali, Not set
Fakultni Nemocnice Brno /ID# 128176, Brno, Not set
Masarykuv onkologicky ustav /ID# 124886, Brno, Not set
Duplicate_FN Hradec Kralove /ID# 127080, Hradec Kralove, Not set
Fakultni nemocnice Olomouc /ID# 124885, Olomouc, Not set
Vseobecna fakultni nemocnice v Praze /ID# 124887, Praha, Not set
Rigshospitalet /ID# 124891, Copenhagen Ø, Hovedstaden
Sygehus Lillebælt, Vejle /ID# 124892, Vejle, Syddanmark
East Tallinn Central Hospital /ID# 126475, Kesklinna Linnaosa, Harjumaa
Docrates Cancer Center /ID# 124896, Helsinki, Not set
Duplicate_Helsinki Univ Central Hospital /ID# 124897, Helsinki, Not set
Duplicate_Tampere University Hospital /ID# 124898, Tampere, Not set
Vaasa Central Hospital /ID# 132548, Vaasa, Not set
Institut Paoli-Calmettes /ID# 124903, Marseille, Bouches-du-Rhone
Institut Curie /ID# 124902, Paris CEDEX 05, Ile-de-France
Institut de Cancérologie de l'Ouest René Gauducheau /ID# 137726, St Herblain CEDEX, Loire-Atlantique
Institut Curie - site CLCC René Huguenin /ID# 124904, Saint-cloud, Not set
Universitaetsklinik Heidelberg /ID# 126664, Heidelberg, Baden-Wuerttemberg
Universitaetsklinimum Tuebingen /ID# 129968, Tubingen, Baden-Wuerttemberg
Universitaetsklinikum Ulm /ID# 135230, Ulm, Baden-Wuerttemberg
Universitaetsklinikum Koeln /ID# 126905, Köln, Nordrhein-Westfalen
Universitaetsklinikum Carl Gustav Carus an der TU Dresden /ID# 127180, Dresden, Not set
Klinikum rechts der Isar - Technische Universitaet Muenchen /ID# 125256, Munich, Not set
Sana Klinikum Offenbach /ID# 126733, Offenbach am Main, Not set
Semmelweis Egyetem /ID# 132485, Budapest, Not set
Pecsi Tudomanyegyetem Klinikai Kozpont /ID# 125259, Pecs, Not set
Jasz-Nagykun-Szolnok Megyei Hetenyi Geza Korhaz /ID# 124911, Szolnok, Not set
Duplicate_Zala Megyei Korhaz /ID# 131341, Zalaegerszeg, Not set
The Chaim Sheba Medical Center /ID# 124918, Ramat Gan, Tel-Aviv
Tel Aviv Sourasky Medical Center /ID# 130276, Tel Aviv-Yafo, Tel-Aviv
Duplicate_Soroka University Medical Center /ID# 124917, Be'er Sheva, Not set
Assaf Harofeh Medical Center /ID# 124915, Be'Er Ya'Akov, Not set
Rambam Health Care Campus /ID# 124916, Haifa, Not set
Shaare Zedek Medical Center /ID# 130275, Jerusalem, Not set
Gastroenterology Institute, Division of Medicine /ID# 124919, Jerusalem, Not set
Kaplan Medical Center /ID# 124914, Rehovot, Not set
Ospedale San Raffaele IRCCS /ID# 125261, Milan, Lombardia
IEO -Istituto Europeo di Oncologia /ID# 125260, Milan, Milano
IRCCS Ospedale Sacro Cuore Don Calabria /ID# 125262, Negrar, Verona
Centro di Riferimento Oncologico /ID# 126738, Aviano, Not set
Grande Ospedale Metropolitano Bianchi Melacrino Morelli /ID# 125263, Reggio Calabria, Not set
National Cancer Center /ID# 125602, Goyang, Gyeonggido
Yonsei University Health System Severance Hospital /ID# 125599, Seoul, Seoul Teugbyeolsi
Korea University Anam Hospital /ID# 128968, Seoul, Not set
Seoul National University Hospital /ID# 125600, Seoul, Not set
Asan Medical Center /ID# 125601, Seoul, Not set
Samsung Medical Center /ID# 125598, Seoul, Not set
Pauls Stradins Clinical University Hospital /ID# 125264, Riga, Not set
Riga East Clinical University Hospital /ID# 125265, Riga, Not set
Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 125266, Kaunas, Not set
National Cancer Institute /ID# 125267, Vilnius, Not set
Centro de Estudios Clínicos Especializados /ID# 128680, Mérida, Yucatan
Centro Oncologico de Chihuahua /ID# 128679, Chihuahua, Not set
Instituto Nacional de Cancerología INCAN /ID# 128676, Ciudad de Mexico, Not set
Erasmus Medisch Centrum /ID# 124935, Rotterdam, Zuid-Holland
Universitair Medisch Centrum Groningen /ID# 129069, Groningen, Not set
Maastricht Universitair Medisch Centrum /ID# 129068, Maastricht, Not set
Haukeland University Hospital /ID# 150177, Bergen, Hordaland
Wojewodzki Szpital Specjalistyczny /ID# 127258, Wroclaw, Dolnoslaskie
Centrum Onkologii Lukaszczyka /ID# 124938, Bydgoszcz, Kujawsko-pomorskie
Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopern /ID# 126999, Lodz, Lodzkie
MRUK-MED I Spolka z ograniczona odpowiedzialnoscia /ID# 124939, Rzeszow, Podkarpackie
Wojewodzki Szpital Zespolony /ID# 126998, Elblag, Warminsko-mazurskie
Centro Hospitalar de Vila Nova de Gaia/Espinho, EPE /ID# 126510, Vila Nova De Gaia, Porto
Centro Hospitalar Universitário do Algarve, EPE - Hospital Faro /ID# 125298, Faro, Not set
Centro Hospitalar Universitário de Lisboa Norte, EPE - Hospital de Santa Maria /ID# 125299, Lisboa, Not set
Unidade Local de Saúde de Matosinhos, EPE /ID# 126511, Matosinhos, Not set
IPO Porto FG, EPE /ID# 125297, Porto, Not set
Centro Hospitalar Universitario de Sao Joao, EPE /ID# 126508, Porto, Not set
Ad-Vance Medical Research, LLC /ID# 126043, Ponce, Not set
San Juan Municipal Hospital /ID# 124695, San Juan, Not set
S.C. Centrul de Oncologie Sf. Nectarie S.R.L. /ID# 124948, Craiova, Dolj
Duplicate_lnstitutul Oncologic Prof Dr Alexandru Trestioreanu /ID# 124943, Bucharest, Not set
Spitalul Clinic Judetean de Urgenta Cluj -Napoca /ID# 124945, Cluj-Napoca, Not set
Oncomed SRL /ID# 127598, Timisoara, Not set
Sverdlovsk Regional Oncology Dispensary /ID# 130950, Yekaterinburg, Sverdlovskaya Oblast
Regional Oncology Dispensary /ID# 125936, Kursk, Tatarstan, Respublika
Duplicate_archangel Clinical Oncology /ID# 126031, Arkhangelsk, Not set
Altay Regional Oncological Dispesary /ID# 127160, Barnaul, Not set
Belgorod Oncology Dispensary /ID# 129315, Belgorod, Not set
Duplicate_Saratov State Medical University n.s. Chernyshevskiy /ID# 139395, Saratov, Not set
LLC BioEq Ltd. /ID# 134529, St. Petersburg, Not set
Siberian State Medical University /ID# 127161, Tomsk, Not set
Volgograd Regional Clinical Oncology Dispensary /ID# 124952, Volzhsky, Not set
National University Hospital /ID# 125315, Singapore, Not set
Johns Hopkins Singapore IMC /ID# 125316, Singapore, Not set
GVI Oncology /ID# 125321, Gqeberha, Eastern Cape
University of Free State, Universitas Annex (National Hospital Grounds) /ID# 128499, Bloemfontein, Free State
Wits Clinical Research Site /ID# 125317, Johannesburg, Gauteng
Medical Oncology Ctr Rosebank /ID# 125322, Johannesburg, Gauteng
Sandton Oncology Medical Group PTY Ltd /ID# 125323, Johannesburg, Gauteng
Mary Potter Oncology Centre /ID# 133269, Pretoria, Gauteng
The Oncology Centre /ID# 126104, Durban, Kwazulu-Natal
Netcare Oncology Intervent Ctr /ID# 125320, Cape Town, Western Cape
Cancercare Outeniqua Oncology Centre /ID# 125319, George, Western Cape
Hospital Santa Creu i Sant Pau /ID# 124963, Barcelona, Not set
Hospital General Universitario Gregorio Maranon /ID# 124962, Madrid, Not set
Hospital Universitario HM Sanchinarro /ID# 124960, Madrid, Not set
Hospital Universitario Virgen de la Victoria /ID# 124961, Malaga, Not set
Hospital Clinico Universitario de Valencia /ID# 124959, Valencia, Not set
Skane University hospital /ID# 124966, Malmo, Skane Lan
Norrlands University hospital /ID# 124967, Umea, Vasterbottens Lan
Sahlgrenska University Hospital /ID# 124965, Gothenburg, Vastra Gotalands Lan
Linkoping University Hospital /ID# 126795, Linkoping, Not set
Duplicate_Karolinska Univ Sjukhuset /ID# 124964, Solna, Not set
Uppsala University Hospital /ID# 126512, Uppsala, Not set
Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 125575, Kaohsiung, Not set
National Taiwan University Hospital /ID# 125324, Taipei City, Not set
Hacettepe University Faculty of Medicine /ID# 125336, Ankara, Not set
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi /ID# 125337, Ankara, Not set
Duplicate_Akdeniz University Medical Fac /ID# 125339, Antalya, Not set
Bezmi Alem Univ Med Fac Hosp /ID# 127901, Istanbul, Not set
Istanbul University Istanbul Medical Faculty /ID# 145144, Istanbul, Not set
Municipal Non-Profit Enterprise City Clinical Hospital No.4 of Dnipro City Counc /ID# 124968, Dnipro, Not set
Donetsk Regional Antitumor Ctr /ID# 124970, Donetsk, Not set
Communal non-profit enterprise Regional Center of Oncology /ID# 124972, Kharkiv, Not set
Lviv Oncological Regional Therapeutical and Diagnostic Centre /ID# 124974, Lviv, Not set
Poltava Regional Clinical Oncology Centre of Poltava Regional Council /ID# 124969, Poltava, Not set
Zaporizhzhia Med. Academy MOH /ID# 129800, Zaporizhia, Not set
ME Kryviy Rih Oncology Dispensary /ID# 129806, Кривий Ріг, Not set
University Hospitals Bristol /ID# 128343, Bristol, Bristol, City Of
Hull University Teaching Hospitals NHS Trust /ID# 133030, Hull, East Riding Of Yorkshire
Nottingham University Hospitals NHS Trust /ID# 125340, Nottingham, Nottinghamshire
University Hospitals Birmingham NHS Foundation Trust /ID# 125342, Birmingham, Not set
Conditions: Metastatic Breast Cancer
The BURAN Study of Buparlisib in Patients With Recurrent or Metastatic HNSCC
Active Not Recruiting
The BURAN study is a randomized, open-label phase III study to assess the treatment effect of once-daily buparlisib in combination with weekly paclitaxel compared to weekly paclitaxel alone in patients with refractory, recurrent, or metastatic head and neck squamous cell carcinoma (HNSCC) that have progressed after prior anti PD 1/anti PD L1 monotherapy; prior anti PD 1/anti PD L1 therapy in combination with platinum-based therapy; or after sequential treatment of anti PD 1/anti PD L1 therapy, e... Read More
The BURAN study is a randomized, open-label phase III study to assess the treatment effect of once-daily buparlisib in combination with weekly paclitaxel compared to weekly paclitaxel alone in patients with refractory, recurrent, or metastatic head and neck squamous cell carcinoma (HNSCC) that have progressed after prior anti PD 1/anti PD L1 monotherapy; prior anti PD 1/anti PD L1 therapy in combination with platinum-based therapy; or after sequential treatment of anti PD 1/anti PD L1 therapy, either prior to or post, platinum-based therapy. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: City of Hope, Duarte, California +161 locations
City of Hope, Duarte, California
Yale University, Yale Cancer Center, New Haven, Connecticut
Moffitt Cancer Center, Tampa, Florida
Emory University, Atlanta, Georgia
Northwestern University, Chicago, Illinois
University of Kentucky, Lexington, Kentucky
Norton Cancer Institute, Louisville, Kentucky
University of Michigan, Ann Arbor, Michigan
Karmanos Cancer Institute, Detroit, Michigan
Henry Ford Health System, Detroit, Michigan
Washington University School of Medicine, Saint Louis, Missouri
Montefiore Medical Center, Bronx, New York
NYU Langone, New York, New York
Stony Brook University Medical Center, Stony Brook, New York
Duke University Medical Center, Durham, North Carolina
University of Cincinnati Cancer Center, Cincinnati, Ohio
Fox Chase Cancer Center, Philadelphia, Pennsylvania
UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania
Hollings Cancer Center, Charleston, South Carolina
West Cancer Center, Germantown, Tennessee
Hope Cancer Center, UT Health East Texas, Tyler, Texas
Fundacion Cenit para la Investigacion en Neurociencias, Buenos Aires, Not set
Centro de Investigacion Pergamino SA - Clinica Pergamino S.A., Buenos Aires, Not set
Instituto de Investigaciones Metabólicas (IDIM) // Instituto de Investigaciones Metabólicas S.A., Ciudad Autonoma de Buenos Aire, Not set
IONC SRL- Instituto Oncológico de Córdoba, Córdoba, Not set
Fundacion CORI para la Investigacion y Prevencion del Cáncer, La Rioja, Not set
Centro para la Atencion Integral del Paciente Oncologico - CAIPO, Tucuman, Not set
Princess Alexandra Hospital, Brisbane, Not set
Universitair Ziekenhuis Gent UZ Gent, Ghent, Not set
Universitair Ziekenhuis Brussel, Jette, Not set
Clinique CHC MontLégia, Liege, Not set
Clinique Saint-Pierre dOttignies CSPO, Ottignies, Not set
CHUM, Montreal, Not set
CancerCare Manitoba, Winnipeg, Not set
Beijing Tongren Hospital, Beijing, Not set
The First Affiliated Hospital of Bengbu Medical College, Bengbu, Not set
Hunan Cancer Hospital, Changsha, Not set
Xiangya Hospital Central South University, Changsha, Not set
Sichuan Cancer Hospital, Chengdu, Not set
Affiliated Cancer Hospital of Chongqing University, Chongqing, Not set
The First Affiliated Hospital of CQMU, Chongqing, Not set
Sun Yat-sen University Cancer Center, Guangzhou, Not set
Affiliated Cancer Hospital of Guangzhou Medical University, Guangzhou, Not set
Zhejiang Cancer Hospital, Hangzhou, Not set
Anhui Provincial Cancer Hospital, Hefei, Not set
Shandong Provincial Tumor Hospital, Jinan, Not set
Yunnan Cancer Hospital, Kunming, Not set
Cancer Hospital affiliated to Guangxi Medical University, Naning, Not set
Shanghai Dongfang Hospital, Shanghai, Not set
Tianjin Cancer Hospital, Tianjin, Not set
Henan Cancer Hospital, Zhengzhou, Not set
The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Not set
Centre hospitalier Universitaire de Bordeaux, Bordeaux, Not set
Centre Franois Baclesse, Caen, Not set
Centre Leon Berard, Lyon, Not set
Hopital de la Timone, Marseille, Not set
Institut regional du Cancer de Montpellier, Montpellier, Not set
LHopital prive du Confluent Nantes, Nantes, Not set
Clinique Hartmann, Neuilly Sur Seine, Not set
Hôpital St-Louis, Paris, Not set
Hopital La Pitie Salpetriere, Paris, Not set
Hopital Tenon, Paris, Not set
CHP Saint-Grégoire, Saint-Grégoire, Not set
Institut de cancerologie de Lorraine, Vandœuvre-lès-Nancy, Not set
Uniklinik RWTH Aachen, Aachen, Not set
Universitaetsklinikum Bonn, Bonn, Not set
University Hospital Essen, Essen, Not set
Franziskus Hospital, Georgsmarienhütte, Not set
HNO-Klinik des Universitats-Klinikums Giessen, Giessen, Not set
Universitatsmedizin Greifswald - KoR, Greifswald, Not set
Universitatsklinikum Hamburg Eppendorf, Hamburg, Not set
Marienkrankenhaus Hamburg, Hamburg, Not set
Hannover Medical School, Hannover, Not set
Universitatsklinikum Leipzig, Leipzig, Not set
UNIVERSITÄTSMEDIZIN Mainz III. Klinik/Poliklinik, Mainz, Not set
Queen Mary Hospital, Hong Kong, Not set
Orszagos Onkologiai Intezet, Budapest, Not set
University of Pecs Department of Oncotherapy, Pécs, Not set
Tolna Megyei Balassa Janos Korhaz, Szekszárd, Not set
Azienda Ospedaliera Universitaria S.Orsola-Malpighi, Bologna, Not set
ASST Spedali Civili Brescia, Brescia, Not set
Istituto di Candiolo IRCCS, Candiolo, Not set
IRCCS - Istituto Scientifico Romagnolo per la Cura e lo Studio dei Tumori, Cesena, Not set
A.O. S. Croce e Carle, Cuneo, Not set
Azienda Ospedaliero Universitaria Careggi - Firenze, Firenze, Not set
Azienda Ospedaliera San Paolo Polo Universitario, Milano, Not set
Istituto Nazionale dei Tumori, Milan, Not set
INT IRCCS Fondazione G.Pascale, Napoli, Not set
A.O.U. "Maggiore della Carita"- S.C.D.U Oncologiac, Novara, Not set
Azienda Ospedaliero Universitaria Policlinico "Paolo Giaccone" U.O.C. Oncologia Medica, Palermo, Not set
Azienda Ospedaliero Universitaria di Parma, Parma, Not set
IRCCS Maugeri Pavia, Pavia, Not set
IRCCS Istituto Clinico Humanitas, Rozzano, Not set
AOU San Giovanni di Dio e Ruggi D'Aragona, Università degli Studi di Salerno, Salerno, Not set
Azienda Ospedaliera Universitaria Senese Policlinico Le Scotte, Siena, Not set
ASST Valtellina e Alto Lario - UOC Oncologia Medica Ospedale di Sondrio, Sondrio, Not set
AO Card. G. Panico, Tricase, Not set
Azienda Sanitaria Universitaria Integrata di Udine, Udine, Not set
Azienda Ospedaliera Universitaria Integrata Verona, Verona, Not set
Hyogo Cancer Center, Akashi-shi, Not set
National Cancer Center Hospital, Chuo Ku, Not set
Kyushu University Hospital, Fukuoka shi, Not set
Saitama Medical University International Medical Center, Hidaka, Not set
Kagawa University Hospital, Kita-gun, Not set
Kobe University Hospital, Kobe, Not set
The Cancer Institute Hospital of JFCR, Koto-Ku, Not set
National Hospital Organization Shikoku Cancer Center, Matsuyama, Not set
Aichi Cancer Center, Nagoya, Not set
Kindai University Hospital, Osaka Sayama-shi, Not set
Hokkaido University Hospital, Sapporo, Not set
National University Corporation Tohoku University, Tohoku University Hospital, Sendai, Not set
Showa University Hospital, Shinagawa-Ku, Not set
Shizuoka Cancer Center, Shizuoka, Not set
Kosin University Gospel Hospital, Busan, Not set
Gachon University Gil Medical Center, Incheon, Not set
Seoul National University Bundang Hospital, Seongnam-si, Not set
Korea University Anam Hospital, Seoul, Not set
Asan Medical Center, Seoul, Not set
The Catholic University of Korea Seoul ST. Mary's Hospital, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
Ajou University Hospital, Suwon-si, Not set
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie, Gliwice, Not set
Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie, Warszawa, Not set
Fundacion Oncologico de Galicia Jos Antonio Quiroga y Pieyro, A Coruña, Not set
Institut Catala d Oncologia Badalona, Badalona, Not set
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
Vall dHebron Institute of Oncology (VHIO), Barcelona, Not set
Hospital Clinic Barcelona, Barcelona, Not set
Hospital Universitario de Burgos, Burgos, Not set
Hospital Reina Sofia, Córdoba, Not set
Hospital Duran i Reynals - Institut Catala dOncologia ICO, Hospitalet de Llobregat, Not set
Complejo Hospitalario de Jaen, Jaén, Not set
Hospital Universitario Severo Ochoa, Leganés, Not set
Hospital Universitario Lucus Augusti, Lugo, Not set
Clinica Universidad de Navarra, Madrid, Not set
Hospital Universitario Ramon y Cajal, Madrid, Not set
Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Hospital Clinico Universitario Virgen de la Arrixaca, Madrid, Not set
Hospital General Universitario Gregorio Maran, Madrid, Not set
Hospital Puerta de Hierro- Majadahonda, Majadahonda, Not set
Hospital Regional de Malaga, Málaga, Not set
Hospital de Navarra, Pamplona, Not set
Hospital Universitario Marques de Valdecilla, Santander, Not set
Hospital Universitario Santiago de Compostela, Santiago De Compostela, Not set
Valme Hospital Medical Oncology Department, Sevilla, Not set
Instituto Valenciano de Oncologia, Valencia, Not set
Hospital Clinico Universitario Valencia - INCLIVA, Valencia, Not set
Hospital Universitario Miguel Servet, Zaragoza, Not set
Changhua Christian Hospital, Changhua, Not set
Chang Gung Memorial Hospital-KaohSiung, Kaohsiung, Not set
Taichung Veterans General Hospital, Taichung, Not set
National Cheng Kung University Hospital, Tainan, Not set
Chi Mei Medical Center Liouying, Tainan, Not set
Taipei Veterans General Hospital, Taipei, Not set
Chang Gung Memorial Hospital-LinKou, Taoyuan, Not set
Edinburgh Cancer Center, Edinburgh, Not set
Beatson Oncology Centre, Glasgow, Not set
University College London Hospitals, London, Not set
The Royal Marsden NHS Foundation Trust, London, Not set
The Royal Marsden NHS Foundation Trust - Sutton, Sutton, Not set
Conditions: Head and Neck Cancer
A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer
Active Not Recruiting
DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with other anti-cancer agents in patients with HER2-positive Metastatic Breast Cancer
DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with other anti-cancer agents in patients with HER2-positive Metastatic Breast Cancer Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: Research Site, Fort Myers, Florida +71 locations
Research Site, Fort Myers, Florida
Research Site, Saint Petersburg, Florida
Research Site, Commack, New York
Research Site, Harrison, New York
Research Site, New York, New York
Research Site, New York, New York
Research Site, Columbus, Ohio
Research Site, Nashville, Tennessee
Research Site, Fort Worth, Texas
Research Site, Fairfax, Virginia
Research Site, Melbourne, Not set
Research Site, Barretos, Not set
Research Site, Belo Horizonte, Not set
Research Site, Natal, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Rio de Janeiro, Not set
Research Site, Sao Paulo, Not set
Research Site, Sao Paulo, Not set
Research Site, Sorocaba, Not set
Research Site, Montreal, Quebec
Research Site, Quebec, Not set
Research Site, Toronto, Not set
Research Site, Villejuif Cedex, Not set
Research Site, München, Not set
Research Site, Würzburg, Not set
Research Site, Delhi, Not set
Research Site, Gurgaon, Not set
Research Site, Madurai, Not set
Research Site, Mumbai, Not set
Research Site, Bologna, Not set
Research Site, Milan, Not set
Research Site, Napoli, Not set
Research Site, Rome, Not set
Research Site, Busan-si, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Bydgoszcz, Not set
Research Site, Koszalin, Not set
Research Site, Lublin, Not set
Research Site, Łódź, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Saint Petersburg, Not set
Research Site, Sankt-Peterburg, Not set
Research Site, Sankt-Peterburg, Not set
Research Site, Barcelona, Not set
Research Site, L'Hospitalet de Llobregat, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Sevilla, Not set
Research Site, Hualien, Not set
Research Site, Tainan, Not set
Research Site, Taipei City, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taoyuan City, Not set
Research Site, Ankara, Not set
Research Site, Edirne, Not set
Research Site, Istanbul, Not set
Research Site, Istanbul, Not set
Research Site, Izmir, Not set
Research Site, Buckhurst Hill, Not set
Conditions: Metastatic Breast Cancer
Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected
Active Not Recruiting
The objective of this study is to assess the efficacy and safety of the combination of alpelisib and olaparib compared with single agent cytotoxic chemotherapy in patients with platinum resistant or refractory high-grade serous ovarian cancer, with no germline BRCA mutation detected.
The objective of this study is to assess the efficacy and safety of the combination of alpelisib and olaparib compared with single agent cytotoxic chemotherapy in patients with platinum resistant or refractory high-grade serous ovarian cancer, with no germline BRCA mutation detected. Read Less
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
02/10/2025
Locations: Arizona Oncology Associates, Phoenix, Arizona +92 locations
Arizona Oncology Associates, Phoenix, Arizona
HonorHealth, Phoenix, Arizona
Florida Cancer Specialists, Fort Myers, Florida
Florida Cancer Specialists, West Palm Beach, Florida
Maryland Oncology Hematology P A, Silver Spring, Maryland
Massachusetts General Hospital, Boston, Massachusetts
Dana Farber Cancer Institute, Boston, Massachusetts
Memorial Sloan Kettering Cancer Ctr, New York, New York
Oncology Hematology Care Inc, Cincinnati, Ohio
University Of Cincinnati, Cincinnati, Ohio
Avera Cancer Institute, Sioux Falls, South Dakota
Sarah Cannon Research Institute, Nashville, Tennessee
Texas Oncology P A, Bedford, Texas
Texas Oncology, Dallas, Texas
Texas Oncology P A, San Antonio, Texas
Texas Oncology Northeast Texas, Tyler, Texas
Novartis Investigative Site, Caba, Buenos Aires
Novartis Investigative Site, Ciudad Autonoma de Bs As, Buenos Aires
Novartis Investigative Site, Buenos Aires, Not set
Novartis Investigative Site, Bedford Park, South Australia
Novartis Investigative Site, Shepparton, Victoria
Novartis Investigative Site, Sydney, Not set
Novartis Investigative Site, Innsbruck, Tyrol
Novartis Investigative Site, Graz, Not set
Novartis Investigative Site, Bruxelles, Not set
Novartis Investigative Site, Leuven, Not set
Novartis Investigative Site, Namur, Not set
Novartis Investigative Site, Belo Horizonte, Minas Gerais
Novartis Investigative Site, Sao Paulo, SP
Novartis Investigative Site, Calgary, Alberta
Novartis Investigative Site, Vancouver, British Columbia
Novartis Investigative Site, London, Ontario
Novartis Investigative Site, Toronto, Ontario
Novartis Investigative Site, Chengdu, Sichuan
Novartis Investigative Site, Beijing, Not set
Novartis Investigative Site, Jinan, Not set
Novartis Investigative Site, Shanghai, Not set
Novartis Investigative Site, Tianjin, Not set
Novartis Investigative Site, Novy Jicin, Czech Republic
Novartis Investigative Site, Ostrava, Poruba
Novartis Investigative Site, Praha, Not set
Novartis Investigative Site, Herlev, Not set
Novartis Investigative Site, Odense C, Not set
Novartis Investigative Site, Kuopio, Not set
Novartis Investigative Site, Tampere, Not set
Novartis Investigative Site, Turku, Not set
Novartis Investigative Site, Besancon Cedex, Not set
Novartis Investigative Site, Lyon, Not set
Novartis Investigative Site, Paris, Not set
Novartis Investigative Site, Pierre Benite, Not set
Novartis Investigative Site, Villejuif, Not set
Novartis Investigative Site, Mannheim, Baden Wuerttemberg
Novartis Investigative Site, Berlin, Not set
Novartis Investigative Site, Dresden, Not set
Novartis Investigative Site, Essen, Not set
Novartis Investigative Site, Bologna, BO
Novartis Investigative Site, Firenze, FI
Novartis Investigative Site, Milano, MI
Novartis Investigative Site, Milano, MI
Novartis Investigative Site, Roma, RM
Novartis Investigative Site, Vicenza, VI
Novartis Investigative Site, Napoli, Not set
Novartis Investigative Site, Seoul, Not set
Novartis Investigative Site, Seoul, Not set
Novartis Investigative Site, Kota Kinabalu, Sabah
Novartis Investigative Site, Kuching, Sarawak
Novartis Investigative Site, Kuala Lumpur, Wilayah Persekutuan
Novartis Investigative Site, Kuala Lumpur, Not set
Novartis Investigative Site, Monterrey, Nuevo Leon
Novartis Investigative Site, Ciudad de Mexico, Not set
Novartis Investigative Site, Eindhoven, Not set
Novartis Investigative Site, Loures, Not set
Novartis Investigative Site, Porto, Not set
Novartis Investigative Site, Arkhangelsk, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Bratislava, Slovak Republic
Novartis Investigative Site, Cordoba, Andalucia
Novartis Investigative Site, Barcelona, Catalunya
Novartis Investigative Site, Barcelona, Catalunya
Novartis Investigative Site, Valencia, Comunidad Valenciana
Novartis Investigative Site, Pamplona, Navarra
Novartis Investigative Site, Madrid, Not set
Novartis Investigative Site, Taichung, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Adana, Not set
Novartis Investigative Site, Ankara, Not set
Novartis Investigative Site, Ankara, Not set
Novartis Investigative Site, Izmir, Not set
Novartis Investigative Site, Glasgow, Not set
Novartis Investigative Site, London, Not set
Novartis Investigative Site, Manchester, Not set
Conditions: Ovarian Cancer
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer
Active Not Recruiting
A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.
A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer. Read Less
Gender:
FEMALE
Ages:
Between 18 years and 150 years
Trial Updated:
02/10/2025
Locations: Research Site, Tucson, Arizona +201 locations
Research Site, Tucson, Arizona
Research Site, Concord, California
Research Site, La Jolla, California
Research Site, San Francisco, California
Research Site, Santa Barbara, California
Research Site, Aurora, Colorado
Research Site, Fort Lauderdale, Florida
Research Site, Tampa, Florida
Research Site, Savannah, Georgia
Research Site, Honolulu, Hawaii
Research Site, Arlington Heights, Illinois
Research Site, Chicago, Illinois
Research Site, Indianapolis, Indiana
Research Site, Louisville, Kentucky
Research Site, Baton Rouge, Louisiana
Research Site, Boston, Massachusetts
Research Site, Saint Paul, Minnesota
Research Site, Jackson, Mississippi
Research Site, Lebanon, New Hampshire
Research Site, Camden, New Jersey
Research Site, Paramus, New Jersey
Research Site, New York, New York
Research Site, New York, New York
Research Site, Pinehurst, North Carolina
Research Site, Cleveland, Ohio
Research Site, Cleveland, Ohio
Research Site, Dayton, Ohio
Research Site, Oklahoma City, Oklahoma
Research Site, Tulsa, Oklahoma
Research Site, Eugene, Oregon
Research Site, Tigard, Oregon
Research Site, Pittsburgh, Pennsylvania
Research Site, Providence, Rhode Island
Research Site, Sioux Falls, South Dakota
Research Site, Chattanooga, Tennessee
Research Site, Germantown, Tennessee
Research Site, Knoxville, Tennessee
Research Site, Bedford, Texas
Research Site, Dallas, Texas
Research Site, Houston, Texas
Research Site, San Antonio, Texas
Research Site, Sugar Land, Texas
Research Site, Tyler, Texas
Research Site, Webster, Texas
Research Site, Fairfax, Virginia
Research Site, Norfolk, Virginia
Research Site, Seattle, Washington
Research Site, Morgantown, West Virginia
Research Site, Madison, Wisconsin
Research Site, Milwaukee, Wisconsin
Research Site, Clayton, Not set
Research Site, Malvern, Not set
Research Site, Melbourne, Not set
Research Site, Nedlands, Not set
Research Site, Sydney, Not set
Research Site, Bruges, Not set
Research Site, Bruxelles, Not set
Research Site, Charleroi, Not set
Research Site, Gent, Not set
Research Site, Hasselt, Not set
Research Site, Kortrijk, Not set
Research Site, Leuven, Not set
Research Site, Libramont-Chevigny, Not set
Research Site, Liège, Not set
Research Site, Belo Horizonte, Not set
Research Site, Belo Horizonte, Not set
Research Site, Curitiba, Not set
Research Site, Passo Fundo, Not set
Research Site, Pelotas, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Rio de Janeiro, Not set
Research Site, Sao Paulo, Not set
Research Site, Sao Paulo, Not set
Research Site, São José do Rio Preto, Not set
Research Site, Calgary, Alberta
Research Site, Toronto, Ontario
Research Site, Toronto, Ontario
Research Site, Montreal, Quebec
Research Site, Montreal, Quebec
Research Site, Montreal, Quebec
Research Site, Montreal, Quebec
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Changchun, Not set
Research Site, Changchun, Not set
Research Site, Changsha, Not set
Research Site, Changsha, Not set
Research Site, Chengdu, Not set
Research Site, Chongqing, Not set
Research Site, Chongqing, Not set
Research Site, Dalian, Not set
Research Site, Dalian, Not set
Research Site, Guangdong, Not set
Research Site, Guangzhou, Not set
Research Site, Haikou, Not set
Research Site, Harbin, Not set
Research Site, Hefei, Not set
Research Site, Nanning, Not set
Research Site, Shanghai, Not set
Research Site, Shenyang, Not set
Research Site, Taiyuan, Not set
Research Site, Tianjin, Not set
Research Site, Wuhan, Not set
Research Site, Wuhan, Not set
Research Site, Zhanjiang, Not set
Research Site, Zhengzhou, Not set
Research Site, Zhengzhou, Not set
Research Site, Barranquilla, Not set
Research Site, Bogota, Not set
Research Site, Bogota, Not set
Research Site, Bogota, Not set
Research Site, Cali, Not set
Research Site, Medellin, Not set
Research Site, Medellín, Not set
Research Site, Monteria, Not set
Research Site, Pereira, Not set
Research Site, Tallinn, Not set
Research Site, Tartu, Not set
Research Site, Bonn, Not set
Research Site, Chemnitz, Not set
Research Site, Dresden, Not set
Research Site, Leipzig, Not set
Research Site, Athens, Not set
Research Site, Chaidari, Not set
Research Site, Thessaloniki, Not set
Research Site, HKG, Not set
Research Site, Hong Kong, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Debrecen, Not set
Research Site, Győr, Not set
Research Site, Szolnok, Not set
Research Site, Hisar, Not set
Research Site, Mumbai, Not set
Research Site, Be'er Ya'akov, Not set
Research Site, Hadera, Not set
Research Site, Jerusalem, Not set
Research Site, Nahariya, Not set
Research Site, Tel Aviv, Not set
Research Site, Chuo-ku, Not set
Research Site, Kashiwa-shi, Not set
Research Site, Koto-ku, Not set
Research Site, Kurume-shi, Not set
Research Site, Kyoto-shi, Not set
Research Site, Matsuyama-shi, Not set
Research Site, Minato-ku, Not set
Research Site, Nagoya-shi, Not set
Research Site, Nakagami-gun, Not set
Research Site, Niigata-shi, Not set
Research Site, Osaka-shi, Not set
Research Site, Osaka, Not set
Research Site, Sapporo-shi, Not set
Research Site, Shinjuku-ku, Not set
Research Site, Sunto-gun, Not set
Research Site, Toon-Shi, Not set
Research Site, Tsu-shi, Not set
Research Site, Yokohama-shi, Not set
Research Site, Goyang-si, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Suwon, Not set
Research Site, Yangsan-si, Not set
Research Site, Kaunas, Not set
Research Site, Vilnius, Not set
Research Site, Vilnius, Not set
Research Site, Aguascalientes, Not set
Research Site, Mexico, Not set
Research Site, Monterrey, Not set
Research Site, Oaxaca, Not set
Research Site, Queretaro, Not set
Research Site, San Luis Potosi, Not set
Research Site, Veracruz, Not set
Research Site, Gdansk, Not set
Research Site, Lublin, Not set
Research Site, Olsztyn, Not set
Research Site, Olsztyn, Not set
Research Site, Łódź, Not set
Research Site, Anzorey, Not set
Research Site, Kazan, Tatarstan, Not set
Research Site, Krasnodar, Not set
Research Site, Moscow, Not set
Research Site, Moscow, Not set
Research Site, Saransk, Not set
Research Site, Sochi, Not set
Research Site, St. Petersburg, Not set
Research Site, Singapore, Not set
Research Site, Singapore, Not set
Research Site, Singapore, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, El Palmar, Not set
Research Site, Girona, Not set
Research Site, Jaén, Not set
Research Site, Madrid, Not set
Research Site, Mallorca, Not set
Conditions: Endometrial Neoplasms
Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients
Active Not Recruiting
This is a Phase III randomised, double-blind, multi-centre study to evaluate the efficacy and safety of durvalumab in combination with standard of care platinum based chemotherapy and bevacizumab followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian cancer.
This is a Phase III randomised, double-blind, multi-centre study to evaluate the efficacy and safety of durvalumab in combination with standard of care platinum based chemotherapy and bevacizumab followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian cancer. Read Less
Gender:
FEMALE
Ages:
Between 18 years and 130 years
Trial Updated:
01/28/2025
Locations: Research Site, Foothill Ranch, California +213 locations
Research Site, Foothill Ranch, California
Research Site, Los Angeles, California
Research Site, Orange, California
Research Site, San Francisco, California
Research Site, Tampa, Florida
Research Site, Augusta, Georgia
Research Site, Hinsdale, Illinois
Research Site, Indianapolis, Indiana
Research Site, Towson, Maryland
Research Site, Detroit, Michigan
Research Site, Springfield, Missouri
Research Site, Middletown, New Jersey
Research Site, Montvale, New Jersey
Research Site, Albany, New York
Research Site, New York, New York
Research Site, Uniondale, New York
Research Site, Durham, North Carolina
Research Site, Cleveland, Ohio
Research Site, Dayton, Ohio
Research Site, Hilliard, Ohio
Research Site, Tulsa, Oklahoma
Research Site, Lancaster, Pennsylvania
Research Site, Philadelphia, Pennsylvania
Research Site, Philadelphia, Pennsylvania
Research Site, Pittsburgh, Pennsylvania
Research Site, Salt Lake City, Utah
Research Site, Graz, Not set
Research Site, Innsbruck, Not set
Research Site, Linz, Not set
Research Site, Wien, Not set
Research Site, Aalst, Not set
Research Site, Leuven, Not set
Research Site, Namur, Not set
Research Site, Oostende, Not set
Research Site, Sint-Niklaas, Not set
Research Site, Barretos, Not set
Research Site, Florianópolis, Not set
Research Site, Fortaleza, Not set
Research Site, Londrina, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Rio de Janeiro, Not set
Research Site, Sao Paulo, Not set
Research Site, São Paulo, Not set
Research Site, Burgas, Not set
Research Site, Plovdiv, Not set
Research Site, Sofia, Not set
Research Site, Varna, Not set
Research Site, Calgary, Alberta
Research Site, Barrie, Ontario
Research Site, Sudbury, Ontario
Research Site, Toronto, Ontario
Research Site, Montreal, Quebec
Research Site, Montreal, Quebec
Research Site, Montreal, Quebec
Research Site, Rimouski, Quebec
Research Site, Quebec, Not set
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Bengbu, Not set
Research Site, Changchun, Not set
Research Site, Changsha, Not set
Research Site, Changsha, Not set
Research Site, Chengdu, Not set
Research Site, Chongqing, Not set
Research Site, Dalian, Not set
Research Site, Guangzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Harbin, Not set
Research Site, Hefei, Not set
Research Site, Jinhua, Not set
Research Site, Kunming, Not set
Research Site, Lanzhou, Not set
Research Site, Luzhou, Not set
Research Site, Nan Chong, Not set
Research Site, Nanjing, Not set
Research Site, Nanning, Not set
Research Site, Nantong, Not set
Research Site, Shanghai, Not set
Research Site, Shanghai, Not set
Research Site, Wuhan, Not set
Research Site, Wuhan, Not set
Research Site, Xi'an, Not set
Research Site, Zhengzhou, Not set
Research Site, Zhengzhou, Not set
Research Site, Zhuhai, Not set
Research Site, Aalborg, Not set
Research Site, Aarhus N, Not set
Research Site, Odense, Not set
Research Site, Roskilde, Not set
Research Site, Vejle, Not set
Research Site, Kuopio, Not set
Research Site, Oulu, Not set
Research Site, Turku, Not set
Research Site, Besançon, Not set
Research Site, Bordeaux, Not set
Research Site, Limoges Cedex, Not set
Research Site, Lyon Cedex 08, Not set
Research Site, Marseille, Not set
Research Site, Nantes, Not set
Research Site, Paris Cedex 14, Not set
Research Site, Paris, Not set
Research Site, Paris, Not set
Research Site, Saint Herblain Cedex, Not set
Research Site, Vandoeuvre les Nancy, Not set
Research Site, Bad Homburg, Not set
Research Site, Berlin, Not set
Research Site, Bielefeld, Not set
Research Site, Bonn, Not set
Research Site, Brandenburg, Not set
Research Site, Dresden, Not set
Research Site, Düsseldorf, Not set
Research Site, Essen, Not set
Research Site, Essen, Not set
Research Site, Esslingen am Neckar, Not set
Research Site, Frankfurt, Not set
Research Site, Freiburg, Not set
Research Site, Fürth, Not set
Research Site, Greifswald, Not set
Research Site, Gütersloh, Not set
Research Site, Hamburg, Not set
Research Site, Hamburg, Not set
Research Site, Hamburg, Not set
Research Site, Hannover, Not set
Research Site, Hannover, Not set
Research Site, Jena, Not set
Research Site, Karlsruhe, Not set
Research Site, Karlsruhe, Not set
Research Site, Kassel, Not set
Research Site, Kiel, Not set
Research Site, Köln, Not set
Research Site, Leipzig, Not set
Research Site, Ludwigsburg, Not set
Research Site, Lübeck, Not set
Research Site, Mainz, Not set
Research Site, Mannheim, Not set
Research Site, München, Not set
Research Site, Offenbach am Main, Not set
Research Site, Oldenburg, Not set
Research Site, Rosenheim, Not set
Research Site, Rostock, Not set
Research Site, Saalfeld, Not set
Research Site, Schweinfurt, Not set
Research Site, Tübingen, Not set
Research Site, Ulm, Not set
Research Site, Worms, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Debrecen, Not set
Research Site, Győr, Not set
Research Site, Kaposvár, Not set
Research Site, Szeged, Not set
Research Site, Zalaegerszeg, Not set
Research Site, Brescia, Not set
Research Site, Lecce, Not set
Research Site, Lecco, Not set
Research Site, Milano, Not set
Research Site, Milano, Not set
Research Site, Mirano, Not set
Research Site, Napoli, Not set
Research Site, Reggio Calabria, Not set
Research Site, Reggio Emilia, Not set
Research Site, Roma, Not set
Research Site, Torino, Not set
Research Site, Torino, Not set
Research Site, Fukuoka-shi, Not set
Research Site, Kashiwa-shi, Not set
Research Site, Kobe-shi, Not set
Research Site, Koto-ku, Not set
Research Site, Kurume-shi, Not set
Research Site, Kyoto-shi, Not set
Research Site, Minato-ku, Not set
Research Site, Nagoya-shi, Not set
Research Site, Niigata-shi, Not set
Research Site, Okayama-shi, Not set
Research Site, Sapporo-shi, Not set
Research Site, Sendai-shi, Not set
Research Site, Shinjuku-ku, Not set
Research Site, Sunto-gun, Not set
Research Site, Toyoake-shi, Not set
Research Site, Goyang-si, Not set
Research Site, Seongnam-si, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Suwon-si, Not set
Research Site, Bellavista, Not set
Research Site, La Libertad, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, San Isidro, Not set
Research Site, Gdynia, Not set
Research Site, Szczecin, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Łódź, Not set
Research Site, Floresti, Not set
Research Site, Córdoba, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Terrassa(Barcelona), Not set
Research Site, Vigo, Not set
Research Site, Adana, Not set
Research Site, Ankara, Not set
Research Site, Ankara, Not set
Research Site, Istanbul, Not set
Research Site, Istanbul, Not set
Research Site, Izmir, Not set
Conditions: Advanced Ovarian Cancer
CHemotherapy and Stool Transplant in PDAC (CHASe-PDAC)
Recruiting
To confirm the safety of combining oral fecal microbiota transplantation (FMT) with gemcitabine and nab-paclitaxel chemotherapy as first line treatment in patients with unresectable or metastatic pancreatic ductal adenocarcinoma.
To confirm the safety of combining oral fecal microbiota transplantation (FMT) with gemcitabine and nab-paclitaxel chemotherapy as first line treatment in patients with unresectable or metastatic pancreatic ductal adenocarcinoma. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2025
Locations: Verspeeten Family Cancer Centre (formerly known as the London Regional Cancer Program) London Health Sciences Centre, London, Ontario
Verspeeten Family Cancer Centre (formerly known as the London Regional Cancer Program) London Health Sciences Centre, London, Ontario
Conditions: Unresectable or Metastatic Advanced Pancreatic Ductal Adenocarcinoma
Avelumab in First-line NSCLC (JAVELIN Lung 100)
Completed
The purpose of this study was to demonstrate superiority with regard to Overall Survival (OS) or Progression Free Survival (PFS) of avelumab versus platinum-based doublet, based on an Independent Review Committee assessment, in Non-small cell lung cancer (NSCLC) participants with Programmed death ligand 1+ (PD-L1+) tumors.
The purpose of this study was to demonstrate superiority with regard to Overall Survival (OS) or Progression Free Survival (PFS) of avelumab versus platinum-based doublet, based on an Independent Review Committee assessment, in Non-small cell lung cancer (NSCLC) participants with Programmed death ligand 1+ (PD-L1+) tumors. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/20/2025
Locations: Clearview Cancer Institute, Huntsville, Alabama +348 locations
Clearview Cancer Institute, Huntsville, Alabama
Arizona Center for Cancer Care, Surprise, Arizona
Sharp Memorial Hospital, San Diego, California
University Cancer Institute, Boynton Beach, Florida
South Georgia Medical Center, Valdosta, Georgia
Christus Cancer Treatment Center, Shreveport, Louisiana
Henry Ford Hospital, Detroit, Michigan
St. Vincent Frontier Cancer Center, Billings, Montana
Nevada Cancer Research Foundation, Las Vegas, Nevada
San Juan Oncology Associates, Farmington, New Mexico
Novant Health Oncology Specialists, Kernersville, North Carolina
Mercy Research, Oklahoma City, Oklahoma
Kaiser Permanente Northwest, Portland, Oregon
Lancaster Cancer Center, Lancaster, Pennsylvania
Cookeville Regional Medical Center, Cookeville, Tennessee
Thompson Cancer Survival Center, Knoxville, Tennessee
Coastal Bend Cancer Center, Corpus Christi, Texas
Oncology Consultants, P.A., Houston, Texas
University of Vermont Medical Center, Burlington, Vermont
Northwest Medical Specialties, PLLC, Tacoma, Washington
Cheyenne Regional Medical Center, Cheyenne, Wyoming
Albury Wodonga Regional Cancer Centre, Albury, New South Wales
Coffs Harbour Health Campus, Coffs Harbour, New South Wales
St George Private Hospital, Kogarah, New South Wales
Lismore Base Hospital, Lismore, New South Wales
Orange Health Service, Orange, New South Wales
Royal North Shore Hospital, St Leonards, New South Wales
Calvary Mater Newcastle, Waratah, New South Wales
Gallipoli Medical Research Foundation Ltd, Greenslopes, Queensland
Gold Coast University Hospital, Southport, Queensland
The Queen Elizabeth Hospital, Woodville South, South Australia
Ballarat Base Hospital, Ballarat, Victoria
Bendigo Hospital, Bendigo, Victoria
South West Healthcare, Warrnambool, Victoria
Fiona Stanley Hospital, Murdoch, Western Australia
ZNA Middelheim, Antwerpen, Not set
A.Z. Klina, Brasschaat, Not set
CHU Ambroise Paré, Mons, Not set
NOB - Núcleo de Oncologia da Bahia, Salvador, Bahia
CRIO - Centro Regional Integrado de Oncologia, Fortaleza, Ceará
CEBROM - Centro Brasileiro de Radioterapia, Oncologia e Mastologia, Goiânia, Goiás
Hospital Erasto Gaertner - Liga Paranaense de Combate ao Câncer, Curitiba, Paraná
Hospital de Caridade de Ijuí, Ijuí, Rio Grande Do Sul
Hospital Bruno Born, Lajeado, Rio Grande Do Sul
Hospital São Vicente de Paulo, Passo Fundo, Rio Grande Do Sul
Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul
IMV-Pesquisa Cardiologica Sociedade Simples - HMD - COR, Porto Alegre, Rio Grande Do Sul
Hospital São Lucas da PUCRS, Porto Alegre, Rio Grande Do Sul
Hospital Nossa Senhora da Conceição, Porto Alegre, Rio Grande Do Sul
CEPON - Centro de Pesquisas Oncológicas de Santa Catarina, Florianópolis, Santa Catarina
Clínica de Neoplasias Litoral Ltda., Itajaí, Santa Catarina
Hospital de Câncer de Barretos - Fundação Pio XII, Barretos, Sao Paulo
Fundação Doutor Amaral Carvalho, Jaú, Sao Paulo
CEPHO - Centro de Estudos e Pesquisas em Hematologia e Oncologia, Santo Andre, Sao Paulo
Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto, Sao Paulo
ICESP - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira, São Paulo, Sao Paulo
IBCC - Instituto Brasileiro de Controle do Câncer, São Paulo, Sao Paulo
INCA - Instituto Nacional de Câncer, Rio de Janeiro, Not set
Complex Oncological Center - Ruse, EODD, Ruse, Not set
MHAT for women's health - Nadezhda, OOD, Sofia, Not set
UMHAT "Sv. Ivan Rilski", EAD, Sofia, Not set
Shato, Ead, Sofia, Not set
The Moncton Hospital, Moncton, New Brunswick
Mount Sinai Hospital, Toronto, Ontario
FALP - Fundación Arturo López Pérez, Santiago, Not set
Clinica Santa Maria, Santiago, Not set
IRAM - Instituto de Radio Medicina, Santiago, Not set
Hospital Militar de Santiago, Santiago, Not set
Hospital Clínico San Borja Arriaran, Santiago, Not set
Hospital Clínico Universidad de Chile, Santiago, Not set
Hospital Clinico Viña del Mar, Viña del Mar, Not set
Centro de Investigaciones Clinicas Viña del Mar, Viña del Mar, Not set
Beijing Cancer Hospital, Beijing, Beijing
Guangdong General Hospital, Guangzhou, Guangdong
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang
Liaoning Cancer Hospital & Institute, Shenyang, Liaoning
Linyi Cancer Hospital, Linyi, Shandong
Administradora Country S.A., Bogotá, Not set
Fundación Oftalmológica de Santander - FOSCAL, Floridablanca, Not set
Hospital Pablo Tobón Uribe, Medellín, Not set
IPS IMAT- Instituto Medico de Alta Tecnologia - Oncomedica S.A., Monteria, Not set
University Clinic for Pulmonary Diseases, Zagreb, Not set
University Hospital Centre "Sestre Milosrdnice", Zagreb, Not set
Bank of Cyprus Oncology Center, Nicosia, Not set
Krajska nemocnice Liberec, a.s., Liberec, Not set
Nemocnice Na Plesi s.r.o., Nova Ves pod Plesi, Not set
Fakultni nemocnice Olomouc, Olomouc, Not set
Vitkovicka nemocnice a.s, Ostrava - Vitkovice, Not set
Thomayerova nemocnice, Praha 4 - Krc, Not set
Krajska zdravotni, a.s. - Masarykova nemocnice v Usti nad Labem, o.z., Usti nad Labem, Not set
Herning Sygehus, Herning, Not set
Roskilde Sygehus, Roskilde, Not set
North Estonia Medical Centre Foundation, Tallinn, Not set
Centre Antoine Lacassagne, Nice cedex 02, Alpes Maritimes
CHU de Strasbourg - Nouvel Hôpital Civil, Strasbourg, Bas Rhin
Hôpital Nord - AP-HM Marseille#, Marseille cedex 20, Bouches-du-Rhône
Hôpital privé Clairval, Marseille, Bouches-du-Rhône
CHU Besançon - Hôpital Jean Minjoz, Besancon Cedex, Doubs
CHU Brest - Hôpital Morvan, Brest Cedex, Finistere
Groupe Hospitalier Sud - Hôpital Haut-Lévêque, Pessac, Gironde
CHU Angers - Hôpital Hôtel Dieu#, Angers Cedex 9, Maine Et Loire
Hôpital Cochin, Paris cedex 14, Paris
Centre Hospitalier de la Côte Basque, Bayonne, Pyrenees Atlantiques
Centre Hospitalier de la Croix Rousse, Lyon cedex 04, Rhone
Clinique Victor Hugo - Centre Jean Bernard, Le Mans Cedex 02, Sarthe
Institut Sainte Catherine, Avignon Cedex 9, Vaculuse
Centre Hospitalier Intercommunal de Créteil, Creteil cedex, Val De Marne
Hôpital Saint-Louis - Paris, Paris Cedex 10, Not set
Universitaetsklinikum Heidelberg, Heidelberg, Baden Wuerttemberg
LungenClinic Grosshansdorf GmbH, Grosshansdorf, Schleswig Holstein
251 General Air Force Hospital, Athens, Not set
General Hospital of Athens of Chest Diseases "SOTIRIA", Athens, Not set
University General Hospital "Attikon", Athens, Not set
General Oncology Hospital of Kifissia " Agioi Anargyroi", Athens, Not set
Metropolitan General Hospital, Athens, Not set
University General Hospital of Heraklion, Heraklion, Not set
University General Hospital of Patra, Patras, Not set
Euromedica General Clinic Thessaloniki, Thessaloniki, Not set
Orszagos Koranyi Pulmonologiai Intezet, Budapest, Not set
Orszagos Onkologiai Intezet, Budapest, Not set
Semmelweis Egyetem, Budapest, Not set
Orszagos Koranyi Pulmonologiai Intezet, Budapest, Not set
Csongrad Megyei Mellkasi Betegsegek Szakkorhaza, Deszk, Not set
Petz Aladar Megyei Oktato Korhaz, Györ, Not set
Borsod-Abauj-Zemplen Megyei Kozponti Korhaz es Egyetemi Oktatokorhaz, Miskolc, Not set
SzSzB Megyei Korhazak es Egyetemi Oktatokorhaz, Nyiregyhaza, Not set
Tolna Megyei Balassa Janos Korhaz, Szekszard, Not set
Tudogyogyintezet Torokbalint, Torokbalint, Not set
Zala Megyei Szent Rafael Korhaz, Zalaegerszeg, Not set
Cork University Hospital, Cork, Not set
Soroka University Medical Center, Beer Sheva, Not set
Rambam Health Care Center, Haifa, Not set
Hadassah University Hospital - Ein Kerem, Jerusalem, Not set
Sapir Medical Center, Meir Hospital, Kfar-Saba, Not set
Rabin Medical Center-Beilinson Campus, Petach Tikva, Not set
Chaim Sheba Medical Center, Ramat Gan, Not set
Kaplan Medical Center, Rechovot, Not set
Assaf Harofeh, Rishon Lezion, Not set
Tel Aviv Sourasky Medical Center, Tel Aviv, Not set
Ospedale Mater Salutis, Legnago, Verona
Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Not set
Presidio Ospedaliero Garibaldi Nesima, Catania, Not set
Azienda Ospedaliero Universitaria San Martino, Genova, Not set
Seconda Università degli Studi di Napoli, Napoli, Not set
Azienda Ospedaliero Universitaria di Parma, Parma, Not set
Azienda Ospedaliero Universitaria Pisana, Pisa, Not set
National Cancer Center Hospital East, Kashiwa-shi, Chiba-Ken
Kurume University Hospital, Kurume-shi, Fukuoka-Ken
NHO Hokkaido Cancer Center, Sapporo-shi, Hokkaido
Institute of Biomedical Research and Innovation Hospital, Kobe-shi, Hyogo-Ken
Kobe City Hospital Organization Kobe City Medical Center General Hospital, Kobe-shi, Hyogo-Ken
Yokohama Municipal Citizen's Hospital, Yokohama-shi, Kanagawa-Ken
Kanagawa Cancer Center, Yokohama-shi, Kanagawa-Ken
Kansai Medical University Hospital, Hirakata-shi, Osaka-Fu
Osaka Medical College Hospital, Takatsuki-shi, Osaka-Fu
National Cancer Center Hospital, Chuo-ku, Tokyo-To
Tokyo Medical University Hospital, Shinjuku-ku, Tokyo-To
Toyama University Hospital, Toyama-shi, Toyama-Ken
Kobe City Hospital Organization Kobe City Medical Center General Hospital, Kobe-shi, Not set
Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do
Yonsei University Wonju Severance Christian Hospital, Wonju-si, Gangwon-do
Inje University Haeundae Paik Hospital, Busan, Gyeonggi-do
National Cancer Center, Goyang-si, Gyeonggi-do
CHA Bundang Medical Center, CHA University, Seongnam-si, Gyeonggi-do
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do
The Catholic University of Korea, St. Vincent's Hospital, Suwon-si, Gyeonggi-do
Ajou University Hospital, Suwon-si, Gyeonggi-do
Kyungpook National University Chilgok Hospital, Daegu, Not set
Gachon University Gil Medical Center, Incheon, Not set
Korea University Anam Hospital, Seoul, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital, Yonsei University, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Not set
The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
Ulsan University Hospital, Ulsan, Not set
American University of Beirut Medical Center, Beirut, Not set
Rafik Hariri University Hospital, Beirut, Not set
Hotel Dieu de France Hospital, Beirut, Not set
Mount Lebanon Hospital, Beirut, Not set
Hammoud Hospital University Medical Center, Saida, Not set
Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, Not set
Martini Ziekenhuis, Groningen, Not set
Westfriesgasthuis - PARENT, Hoorn, Not set
ETZ Elisabeth, Tilburg, Not set
Auckland City Hospital, Auckland, Not set
Dunedin Public Hospital, Dunedin, Not set
Waikato Hospital, Hamilton, Not set
Palmerston North Hospital, Palmerston North, Not set
Tauranga Hospital, Tauranga, Not set
Wellington Hospital, Wellington, Not set
Instituto Nacional de Enfermedades Neoplásicas, Lima, Not set
Clinica Internacional Sede San Borja, Lima, Not set
Oncosalud, Lima, Not set
Centrum Terapii Wspolczesnej J.M. Jasnorzewska sp. komandytowo-akcyjna, Lodz, Not set
Instytut MSF Sp. o.o, Lodz, Not set
Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Łodzi, Lodz, Not set
KO-MED Centra Kliniczne Lublin II, Lublin, Not set
SSZZOZ im. Dr Teodora Dunina w Rudce, Mrozy, Not set
SP Zespol Gruzlicy i Chorob Pluc w Olsztynie, Olsztyn, Not set
Mazowieckie Centrum Leczenia Chorob Pluc i Gruzlicy, Otwock, Not set
Szpital Kliniczny Przemienienia Panskiego Uniwersytetu Medycznego im. Karola Marcinkowskiego, Poznan, Not set
Izerskie Centrum Pulmonologii i Chemioterapii "IZER-MED" Spolka z o.o., Szklarska Poręba, Not set
Centrum Onkologii-Instytut im. M. Sklodowskiej Curie, Warszawa, Not set
Mazowiecki Szpital Onkologiczny, Wieliszew, Not set
Hospital Garcia de Orta, EPE, Almada, Not set
Hospital Professor Doutor Fernando Fonseca, E.P.E., Amadora-Lisbon, Not set
Centro Hospitalar De Coimbra-CHUC, Coimbra, Not set
Centro Hospitalar e Universitário de Coimbra, E.P.E (CHC), Coimbra, Not set
Centro Hospitalar de Lisboa Norte, E.P.E. - Hospital Pulido Valente, Lisboa, Not set
Centro Hospitalar de Lisboa Central, E.P.E. - Hospital de Santo António dos Capuchos, Lisboa, Not set
Centro Hospitalar do Porto, E.P.E. - Hospital de Santo António, Porto, Not set
Hospital CUF Porto, Porto, Not set
Instituto Português de Oncologia do Porto Francisco Gentil, EPE, Porto, Not set
Centro Hospitalar de São João, E.P.E., Porto, Not set
Centro Hospitalar de Entre o Douro e Vouga, E.P.E - Hospital de São Sebastião, Santa Maria da Feira, Not set
Centro Hospitalar Vila Nova de Gaia/Espinho, E.P.E, Vila Nova de Gaia, Not set
Spitalul Judetean de Urgenta "Dr. Constantin Opris" Baia Mare, Baia Mare, Not set
S.C Policlinica de Diagnostic Rapid S.A, Brasov, Not set
Institutul Oncologic "Prof. Dr. Al. Trestioreanu", Bucuresti, Not set
Spitalul Clinic Coltea, Bucuresti, Not set
S.C Gral Medical S.R.L, Bucuresti, Not set
Institutul Oncologic "Prof. Dr. Ion Chiricuta" Cluj Napoca, Cluj Napoca, Not set
S.C Medisprof S.R.L, Cluj-Napoca, Not set
Spitalul Militar de Urgenta "Dr.Constantin Papilian"Cluj -Napoca, Cluj-Napoca, Not set
S.C Radiotherapy Center Cluj S.R.L, Comuna Floresti, Not set
Spitalul Clinic Judetean de Urgenta "Sf. Apostol Andrei" Constanta, Constanta, Not set
S.C Centrul de Oncologie Sf. Nectarie S.R.L, Craiova, Not set
Institutul Regional de Oncologie Iasi, Iasi, Not set
S.C Pelican Impex S.R.L, Oradea, Not set
Spitalul Clinic Municipal "Dr. Gavril Curteanu" Oradea, Oradea, Not set
Spitalul Judetean de Urgenta "Sf. Ioan cel Nou" Suceava, Suceava, Not set
S.C Oncocenter Oncologie Clinica S.R.L, Timisoara, Not set
S.C Oncomed S.R.L, Timisoara, Not set
SBIH of Arkhangelsk region "Arkhangelsk Clinical Oncological Dispensary", Arkhangelsk, Not set
LLC Evimed, Chelyabinsk, Not set
Chelyabinsk Regional Oncology Dispensary, Chelyabinsk, Not set
Irkutsk Regional Oncology Dispensary, Irkutsk, Not set
RBIH "Ivanovo Regional Oncological Dispensary", Ivanovo, Not set
SBHI of Kaluga Region "Kaluga regional clinical oncology dispensary", Kaluga, Not set
SAIH "Republican Clinical Oncological Dispensary of the Ministry of Healthcare of Republic Tatarstan, Kazan, Not set
Kemerovo SPI Regional Clinical Oncology Dispensary, Kemerovo, Not set
SBHI "Krasnoyarsk Regional Oncology Dispensary n.a. A.I. Kryzhanovsky", Krasnoyarsk, Not set
RBIH "Kursk regional clinical oncology dispensary" of Kursk Region Healthcare Committee, Kursk, Not set
FSBSI "Russian Oncological Scientific Center n.a. N.N. Blokhin", Moscow, Not set
Murmansk Regional Clinical Hospital named after Bayandin, Murmansk, Not set
SBHI of Novosibirsk region "Novosibirsk Regional Oncological Dispensary", Novosibirsk, Not set
SBIH of Stavropol territory "Pyatigorsk Oncological Dispensary", Pyatigorsk, Not set
SBIH "Leningrad Regional Oncological Dispensary", Saint-Petersburg, Not set
"Bio Eq" LLC, Saint-Petersburg, Not set
FBI "Scientific Research Institute of Oncology n. a. N. N. Petrov", Saint-Petersburg, Not set
SBIH "Samara Regional Clinical Oncological Dispensary", Samara, Not set
SBIH "Oncological Dispensary # 2" of the MoH of Krasnodar territory, Sochi, Not set
FSBHI Clinical research institute of phthisiopulmonology, St. Petersburg, Not set
Tomsk Research Instutite of Oncology, Tomsk, Not set
BHI of Omsk region "Clinical Oncology Dispensary", Tomsk, Not set
Medicinskiy gorod, Tyumen, Not set
SBIH of Yaroslavl region "Regional Clinical Oncological Hospital", Yaroslavl, Not set
Clinical Center of Serbia, Belgrade, Not set
Institute of Oncology and Radiology of Serbia, Belgrade, Not set
Military Medical Academy, Belgrade, Not set
Clinical Center Bezanijska Kosa, Belgrade, Not set
Clinical Center Nis, Pulmonary Diseases Clinic, Gornji Matejevac, Not set
Clinical Center Kragujevac, Kragujevac, Not set
Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Not set
National University Cancer Institute, Singapore, Not set
National Cancer Centre, Singapore, Not set
Tan Tock Seng Hospital, Singapore, Not set
Nemocnica s poliklinikou Sv. Jakuba, n.o. Bardejov, Bardejov, Not set
Univerzitna nemocnica Bratislava, Nemocnica Ruzinov, Bratislava, Not set
Emery Clinical Services, Alberton, Gauteng
University of Pretoria Oncology Department, Pretoria, Gauteng
Johese Clinical Research, Pretoria, Gauteng
Cape Town Oncology Trials Pty Ltd, Cape Town, Western Cape
Hospital de Mataro, Mataro, Barcelona
Hospital Universitario Mutua de Terrassa, Terrassa, Barcelona
Hospital Universitario Donostia, San Sebastian, Guipuzcoa
Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, La Coruña
Complejo Hospitalario Universitario de Vigo, Vigo, Pontevedra
Specialist, Barcelona, Not set
Hospital Universitari Quiron Dexeus, Barcelona, Not set
Hospital Universitari Vall d'Hebron, Barcelona, Not set
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
ICO Girona - Hospital Universitari de Girona Dr. Josep Trueta, Girona, Not set
Hospital General Universitario Gregorio Marañon, Madrid, Not set
MD Anderson Cancer Centre, Madrid, Not set
Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Hospital Regional Universitario de Malaga, Málaga, Not set
Hospital Quiron Sagrado Corazon, Sevilla, Not set
Hospital Universitario Virgen del Rocio, Sevilla, Not set
Hospital Txagorritxu, Vitoria, Not set
Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Not set
China Medical University Hospital, Taichung, Not set
Taichung Veterans General Hospital, Taichung, Not set
National Taiwan University Hospital, Taipei, Not set
Taipei Veterans General Hospital, Taipei, Not set
Tri-Service General Hospital, Taipei, Not set
Chang Gung Memorial Hospital, Linkou, Taoyuan County, Not set
King Chulalongkorn Memorial Hospital, Patumwan, Bangkok
Rajavithi Hospital, Rajathevee, Bangkok
Maharaj Nakorn Chiang Mai Hospital, Muang, Chiang Mai
Srinagarind Hospital, Muang, Khon Kaen
Naresuan University Hospital, Muang, Phitsanulok
Songklanagarind Hospital, Hat Yai, Songkhla
Siriraj Hospital, Bangkok, Not set
Acibadem Adana Hospital, Adana, Not set
Baskent University Adana Application and Research Center, Adana, Not set
Adana Numune Training and Research Hospital, Adana, Not set
Cukurova University Medical Faculty, Adana, Not set
Adana City Hospital, Adana, Not set
Ankara University Medical Faculty, Ankara, Not set
Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Not set
Hacettepe University Medical Faculty, Ankara, Not set
Memorial Antalya Hastanesi, Antalya, Not set
Okmeydani Research and Training Hospital, Istanbul, Not set
Istanbul University Cerrahpasa Medical Faculty, Istanbul, Not set
Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital, Istanbul, Not set
Medipol University Medical Faculty, Istanbul, Not set
Kartal Lutfi Kirdar Research and Training Hospital, Istanbul, Not set
Ege University Medical Faculty, Izmir, Not set
Inonu Uni. Med. Fac., Malatya, Not set
Mersin University Medical Faculty, Mersin, Not set
Sakarya Traning and Research Hospital, Sakarya, Not set
Namik Kemal University, Tekirdag, Not set
CI Chernivtsi RC Oncological Dispensary Bukovinian SMU Ch of Oncology and Radiology, Chernivtsi, Not set
CI Dnipropetrovsk CMCH #4 of Dnipropetrovsk RC Dept of Chemotherapy SI Dnipropetrovsk MA of MOHU, Dnipro, Not set
CI Transcarpathian Cl Onc Center Dep of Surgery#1 SHEI Ivano-Frankivsk NMU, Ivano-Frankivsk, Not set
SI S.P.Grygoriev Institute of Medical Radiology of NAMSU, Kharkiv, Not set
Communal Non-profit Enterprise Regional Center of Oncology, Kharkiv, Not set
Kherson Regional Oncologic Dispensary, Kherson, Not set
Treatment-Diagnostic Center of Private Enterprise of PPC Atsynus, Kropyvnytskyi, Not set
CI Kryvyi Rih Oncological Dispensary of DRC, Kryvyi Rih, Dnipropetrovsk Region, Not set
Kyiv City Clinical Oncological Center, Kyiv, Not set
Treatment-Prevention Institution Volyn Regional Oncological Dispensary, Lutsk, Not set
Lviv State Oncological Regional Treatment and Diagnostic Center, Lviv, Not set
Odesa Regional Oncologic Dispensary, Odesa, Not set
RCI Sumy Regional Clinical Oncological Dispensary, Sumy, Not set
CCCH City Oncological Center SHEI Uzhgorod NU, Uzhgorod, Not set
Podilskyi Regional Oncological Center, Vinnytsia, Not set
Vinnytsia Regional Clinical Oncological Dispensary, Vinnytsia, Not set
Southend University Hospital, Westcliff on Sea, Essex
Cheltenham General Hospital, Cheltenham, Gloucestershire
Chelsea and Westminster Hospital, London, Greater London
Mount Vernon Hospital, Stevenage, Hertfordshire
The Clatterbridge Cancer Centre, Wirral, Merseyside
Royal Stoke University Hospital, Stoke on Trent, Staffordshire
Conditions: First Line Non-Small Cell Lung Cancer
A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors
Active Not Recruiting
An open-label, dose-escalation (Part 1), dose-expansion (Part 2) study to assess the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-155 alone and in combination with paclitaxel or docetaxel.
In Part 1 (dose escalation), participants will receive escalating doses of ABBV-155 monotherapy (Part 1a) or ABBV-155 in combination with paclitaxel or docetaxel (Part 1b).
In Part 2 (dose expansion), participants will receive ABBV-155 monotherapy or in combination therapy. The ABBV-155 mo... Read More
An open-label, dose-escalation (Part 1), dose-expansion (Part 2) study to assess the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-155 alone and in combination with paclitaxel or docetaxel.
In Part 1 (dose escalation), participants will receive escalating doses of ABBV-155 monotherapy (Part 1a) or ABBV-155 in combination with paclitaxel or docetaxel (Part 1b).
In Part 2 (dose expansion), participants will receive ABBV-155 monotherapy or in combination therapy. The ABBV-155 monotherapy cohort will enroll participants with relapsed or refractory (R/R) small cell lung cancer (SCLC) (Part 2a); the ABBV-155 plus a taxane (paclitaxel or docetaxel) combination cohort will enroll participants with R/R non-small cell lung cancer (NSCLC) and breast cancer (Part 2b). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2025
Locations: University of Alabama at Birmingham - Main /ID# 214024, Birmingham, Alabama +39 locations
University of Alabama at Birmingham - Main /ID# 214024, Birmingham, Alabama
Highlands Oncology Group, PA /ID# 201568, Springdale, Arkansas
UC Irvine Medical Center - Chao Family Comprehensive Cancer Center /ID# 206105, Orange, California
Duplicate_Cedars-Sinai Medical Center-West Hollywood /ID# 204267, West Hollywood, California
Univ of Colorado Cancer Center /ID# 208365, Aurora, Colorado
Yale University, Yale Cancer Center /ID# 201542, New Haven, Connecticut
AdventHealth Orlando /ID# 227242, Orlando, Florida
Northwestern University Feinberg School of Medicine /ID# 201563, Chicago, Illinois
Johns Hopkins Bayview Med Cnt /ID# 215095, Baltimore, Maryland
Johns Hopkins Hospital /ID# 201320, Baltimore, Maryland
Dana-Farber Cancer Institute /ID# 201564, Boston, Massachusetts
Duplicate_Henry Ford Hospital /ID# 226852, Detroit, Michigan
Northwell Health - Marcus Ave /ID# 204376, New Hyde Park, New York
Carolina BioOncology Institute /ID# 201577, Huntersville, North Carolina
Univ Hosp Cleveland /ID# 201567, Cleveland, Ohio
University of Oklahoma, Stephenson Cancer Center /ID# 206820, Oklahoma City, Oklahoma
Lifespan Cancer Institute at Rhode Island Hospital /ID# 204256, Providence, Rhode Island
Vanderbilt Ingram Cancer Center /ID# 201575, Nashville, Tennessee
Mary Crowley Cancer Research /ID# 214168, Dallas, Texas
MD Anderson Cancer Center /ID# 201558, Houston, Texas
NEXT Oncology /ID# 204893, San Antonio, Texas
Peter MacCallum Cancer Center /ID# 241676, Melbourne, New South Wales
Cross Cancer Institute /ID# 213838, Edmonton, Alberta
University Health Network_Princess Margaret Cancer Centre /ID# 204539, Toronto, Ontario
Rambam Health Care Campus /ID# 230813, Haifa, H_efa
The Chaim Sheba Medical Center /ID# 230812, Ramat Gan, Tel-Aviv
National Cancer Center Hospital East /ID# 215130, Kashiwa-shi, Chiba
National Cancer Center Hospital /ID# 215003, Chuo-ku, Tokyo
National Cancer Center /ID# 241095, Goyang-si, Gyeonggido
Yonsei University Health System Severance Hospital /ID# 240648, Seoul, Not set
Maastricht Universitair Medisch Centrum /ID# 225220, Maastricht, Limburg
Antoni van Leeuwenhoek /ID# 222260, Amsterdam, Noord-Holland
Erasmus Medisch Centrum /ID# 222341, Rotterdam, Zuid-Holland
Universitair Medisch Centrum Utrecht /ID# 222357, Utrecht, Not set
Pan American Center for Oncology Trials, LLC /ID# 232128, Rio Piedras, Not set
Hospital Universitario Fundacion Jimenez Diaz /ID# 239997, Madrid, Not set
Hospital Universitario 12 de Octubre /ID# 239999, Madrid, Not set
National Taiwan University Hospital /ID# 205673, Taipei City, Taipei
China Medical University Hospital /ID# 214062, Taichung, Not set
National Cheng Kung University Hospital /ID# 206304, Tainan, Not set
Conditions: Advanced Solid Tumors
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