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All Clinical Trials in Canada
A listing of 3904 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
985 - 996 of 3904
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A Study of Lebrikizumab (LY3650150) in Adult Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
Recruiting
The main purpose of this study is to evaluate the efficacy and safety of lebrikizumab in adult participants with chronic rhinosinusitis and nasal polyps treated with intranasal corticosteroids. The study will last about 18 months.
The main purpose of this study is to evaluate the efficacy and safety of lebrikizumab in adult participants with chronic rhinosinusitis and nasal polyps treated with intranasal corticosteroids. The study will last about 18 months. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/15/2025
Locations: AllerVie Clinical Research, Birmingham, Alabama +157 locations
AllerVie Clinical Research, Birmingham, Alabama
University of Alabama at Birmingham, Birmingham, Alabama
Keck Medicine of USC, Arcadia, California
University of California, Irvine, Irvine, California
DaVinci Research LLC, Roseville, California
Breathe Clear Institute, Torrance, California
Colorado ENT & Allergy, Colorado Springs, Colorado
Orlando ENT & Allergy, Orlando, Florida
NuLine Clinical Trial Center, Pompano Beach, Florida
University of South Florida, Tampa, Florida
Treasure Valley Medical Research, Boise, Idaho
Chicago ENT, Chicago, Illinois
South Louisiana Ear, Nose, Throat & Facial Plastic Surgery - PPDS, Mandeville, Louisiana
Chesapeake Clinical Research, Inc., White Marsh, Maryland
Brigham and Women's Hospital, Boston, Massachusetts
University of Missouri, Columbia, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Madison ENT & Facial Plastic Surgery, New York, New York
UCMC, Cincinnati, Ohio
Optimed Research, LTD, Columbus, Ohio
Specialty Physician Associates, Bethlehem, Pennsylvania
Medical University of South Carolina- Department of Otolaryngology and Head and Neck Surgery, Charleston, South Carolina
UT Southwestern Medical Center, Dallas, Texas
University of Texas Physicians Department of Otorhinolaryngology Clinc, Houston, Texas
Ear Nose and Throat Associates of Texas PA, McKinney, Texas
Alamo ENT Associates, San Antonio, Texas
Eastern Virginia Medical School, Norfolk, Virginia
Richmond Ear Nose and Throat, Richmond, Virginia
The Medical College of Wisconsin, Milwaukee, Wisconsin
UZ Gent, Gent, Oost-Vlaanderen
Pneumocare, Erpent, Not set
Cliniques Universitaires Saint-Luc Avenue Hippocrate 10, Sint-Lambrechts-Woluwe, Not set
Multiprofile Hospital For Active Treatment Dr Tota Venkova A, Gabrovo, Not set
Medical Center Medconsult Pleven OOD, Pleven, Not set
Diagnostic-Consultative Centre Ascendent EOOD, Sofia, Not set
Military Medical Academy - Multiprofile Hospital for Active Treatment - Sofia,, Sofia, Not set
University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna, Sofia, Not set
Multiprofile Hospital for Active treatment Trakia EOOD, Zagora, Not set
St. Joseph's Hospital, Ontario, Not set
CSAC, Québec, Not set
The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui
Peking University Third Hospital, Beijing, Beijing
Beijing Hospital, Beijing, Beijing
The First Affiliated Hospital Of Fujian Medical University, FuZhou, Fujian
The People's Hospital of Guangxi Zhuang Autonomous Region, Nan Ning, Guang XI
Hainan General Hospital, Haikou, Hainan
Renmin Hospital of Wuhan University, Wu Han, Hubei
Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei
Huai'an First People's Hospital, Huai'an, Jiangsu
The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu
The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi
Shengjing Hospital of China Medical University, Shenyang, Liaoning
First People's Hospital of Yinchuan, Yinchuan Shi, Ningxia
The First Hospital of Shanxi Medical University, Taiyuan, Shanxi
Sichuan Provincial People's Hospital, Chengdu, Sichuan
Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang
Beijing Tongren Hospital, Beijing, Not set
The Third Xiangya Hospital of Central South University, Changsha City, Not set
The First People's Hospital of Foshan, Foshan, Not set
Shenzhen Second People's Hospital, Guangdong, Not set
Hangzhou First People's Hospital, Hangzhou City, Not set
The first Affilliated Hospital Shandong First Medical University, Shandong, Not set
Tongji Hospital of Tongji University, Shanghai, Not set
Tianjin People's Hospital, Tianjin, Not set
Tonghua Central Hospital, Tonghua City, Not set
The 2nd Affiliated Hospital of Wenzhou Medical University, Wenzhou Avenue, Not set
Aalborg Universitetshospital Medicinerhuset Lungemedicinsk Forskningsenhed, Aalborg, Not set
Aarhus University Hospital, Dept. of Ear-Nose-Throat, Aarhus, Not set
Bispebjerg Hospital Department of Respiratory Medicine, Copenhagen, Not set
Sjællands Universitets Hospital, Køge, Not set
Universitätsklinikum Schleswig-Holstein, Lübeck, Schleswig-Holstein
Charite-Universitatsmedizin Berlin, Berlin, Not set
HNO Zentrum am Kudamm, Berlin, Not set
Praxis für HNO und Allergologie, Dresden, Not set
Universitätsklinikum Carl Gustav Carus an der TU Dresden, Dresden, Not set
IKF Pneumologie, Frankfurt am Main, Not set
Universitätsklinikum Jena, Jena, Not set
HNO Praxis, Sachsen, Not set
Ospedale San Raffaele, Milano, Lombardia
AOU Careggi- University of Florence, Florence, Not set
AOU Federico II Via Pansini, Napoli, Not set
Azienda Ospedaliera Di Padova, Padova, Not set
Azienda Ospedaliero Universitaria Pisana - Stabilimento Santa Chiara, Pisa, Not set
Fondazione Policlinico A. Gemelli IRCCS, Rome, Not set
ASST Brianza - Vimercate Hospital, Vimercate, Not set
Kimitsu Chuo Hospital, Kisarazu, Chiba
1-8-1, Kishinoura, Kitakyushu, Fukuoka
Mie University Hospital, Tsu, Mie
Osaka Habikino Medical Center, Habikino-shi, Osaka
Kansai Medical University Hospital, Hirakata, Osaka
Kansai Electric Power Hospital, Osaka-shi, Osaka
Kyosai Hospital, Minami-Alps, Yamanashi
University of Yamanashi Hospital, Chuo, Yamanshi
Toyota Memorial Hospital, Aichi, Not set
Clinic Kashiwanoha, Chiba, Not set
University of Fukui Hospital, Fukui, Not set
Saiseikai Fukuoka General Hospital, Fukuoak, Not set
Matsuda Hospital, Fukuoka, Not set
Kyushu University Hospital, Fukuoka, Not set
Hyogo Medical University Hospital, Hyogo, Not set
Takarazuka City Hospital, Hyogo, Not set
Ibaraki Prefectural Central Hospital, Ibaraki, Not set
Kagoshima Kouseiren Hospital, Kagoshima, Not set
Yokohama City Minato Red Cross Hospital, Kanagawa, Not set
Odawara Municipal Hospital, Kanagawa, Not set
3-54-2, Kotohirahommachi, Kumamoto, Not set
Tohoku Medical and Pharmaceutical University Hospital, Miyagi, Not set
Ritsuzankai Iida Hospital, Nagano, Not set
Asahioka, 1-24, Niigata, Not set
Niigata University Medical & Dental Hospital, Niigata, Not set
Japan Community Health care Organization Osaka Hospital, Osaka, Not set
8-2 Otemachi, Shizuoka, Not set
Toho University Ohashi Medical Center, Tokyo, Not set
Nihon University Itabashi Hospital, Tokyo, Not set
JCHO Shimonoseki Medical center, Yamaguchi, Not set
Seoul National University Bundang Hospital, Seongnam-si, Geonggi-do
Ajou University Hospital, Suwon, Gyeonggi-do
Pusan National University Hospital, Pusan, Korea
Korea University Anam Hospital, Seoul, Seoul-teukbyeolsi [Seoul]
Inje University Haeundae Paik Hospital, Busan, Not set
CHA Bundang Medical Center, Gyeonggi-do, Not set
SNUH - Seoul National University Hospital, Seoul, Not set
The Catholic University of Korea, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
SMG-SNU Boramae Medical Center, Seoul, Not set
Niepubliczny Zakład Opieki Zdrowotnej E-Vita, Białystok, Not set
Centrum Medyczne Angelius Provita, Katowice, Not set
B&R Clinical Sp. z o.o, Kielce, Not set
Centrum Medyczne All-Med, Krakow, Not set
Centrum Medyczne Promed ul. Olszańska 5G, Krakow, Not set
Specjalistyczny Niepubliczny Zakład Opieki Zdrowotnej Alergologia Plus Ośrodek Diagnostyki, Poznań, Not set
Centrum Medyczne Biotamed Morawska Barbara, Wieliczka, Not set
EMC INSTYTUT MEDYCZNY S.A. Przychodnia, Wroclaw, Not set
Centrum Medyczne Oporów, Wroclaw, Not set
Centrum Medyczne Pratia Katowice, Katowice, Śląskie
Centrul Medical Unirea SRL, Brasov, Not set
Centrul Medical De Diagnostic Si Tratament Ambulator Neomed S.R.L, Brasov, Not set
Centrul Medical De Diagnostic Si Tratament Ambulator Neomed S.R.L, Brasov, Not set
Euroclinic Hospital SA, Bucharest, Not set
Delta Health Care S.R.L, Bucuresti, Not set
Cardiomed S.R.L, Cluj-Napoca, Not set
Centrul de Excelenta in Rinologie S.R.L, Dolj, Not set
Hospital Universitario Virgen de la Macarena Avenida Dr. Fedriani, Andalucia, Not set
Centro Médico Teknon, Barcelona, Not set
Hospital Universitario de Jerez, Cadiz, Not set
Hospital Clínico Universitario de Santiago, Galícia, Not set
FutureMeds DKF, Madrid, Not set
Hospital Universitario Fundación Jiménez Díaz, Madrid, Not set
Clinica Universidad de Navarra, Pamplona, Not set
Taipei Medical University Shuang Ho Hospital, New Taipei, Not set
National Taiwan University Hospital, Taipei, Not set
Stepping Hill Hospital, Stockport, Cheshire
Charing Cross Hospital, Chelsea, London
Bristol Royal Infirmary University Hospitals, Bristol, Not set
James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, Not set
Royal Berkshire NHS Foundation Trust, London, Not set
Guys and St Thomas' NHS Foundation Trust, London, Not set
Newcastle upon Tyne Hospitals NHSFT Freeman Hospital, Newcastle upon Tyne, Not set
Conditions: Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Anesthesia Clinical Practice During Labour Neuraxial Analgesia
Recruiting
The goal of this observational study is to evaluate the communication between the anesthesiologist and the patient prior the initiation and during the administration of the labor neuraxial analgesia.
The investigators hypothesize that there will be differences among anesthesiologists during the informed consent process and communication during the procedure, specifically, how the anesthesiologists describe the technical aspects of the procedure, alternatives, risks, complications, and expected... Read More
The goal of this observational study is to evaluate the communication between the anesthesiologist and the patient prior the initiation and during the administration of the labor neuraxial analgesia.
The investigators hypothesize that there will be differences among anesthesiologists during the informed consent process and communication during the procedure, specifically, how the anesthesiologists describe the technical aspects of the procedure, alternatives, risks, complications, and expected effects of labour neuraxial analgesia.
The anesthesiologists will be observed during a routine labor neuraxial analgesia procedure for healthy uncomplicated patients. Read Less
Gender:
ALL
Ages:
All
Trial Updated:
07/15/2025
Locations: Department of Anesthesia at BC Women's Hospital, University of British Columbia., Vancouver, British Columbia
Department of Anesthesia at BC Women's Hospital, University of British Columbia., Vancouver, British Columbia
Conditions: Labor Analgesia
Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions
Recruiting
This is a multicenter retrospective comparative cohort study. The index surgery for this study is primary or revision long-segment posterior thoracolumbar (TL) instrumented fusion using either a supplementary rod construct or a dual-rod construct. Eligible patients who already had index surgery, will be identified for enrollment through a review of medical records of the participating surgeons at the study sites.
This is a multicenter retrospective comparative cohort study. The index surgery for this study is primary or revision long-segment posterior thoracolumbar (TL) instrumented fusion using either a supplementary rod construct or a dual-rod construct. Eligible patients who already had index surgery, will be identified for enrollment through a review of medical records of the participating surgeons at the study sites. Read Less
Gender:
ALL
Ages:
45 years and above
Trial Updated:
07/15/2025
Locations: Stanford Spine Clinic, Redwood City, California +15 locations
Stanford Spine Clinic, Redwood City, California
University of California, Sacramento, California
UCSF Spine Center, San Francisco, California
John Hopkis Hospital, Baltimore, Maryland
University of Minnesota Medical Center, Minneapolis, Minnesota
Washington University in St. Louis, School of Medicine, Saint Louis, Missouri
Columbia University / NYP Och Spine Hospital, New York, New York
University of Virginia, Charlottesville, Virginia
University of Calgary Spine, Calgary, Not set
University of Toronto, Toronto, Not set
Duchess of Kent Children's Hospital, Hong Kong, Not set
Kothari Medical Centre, Kolkata, Not set
Hamamatsu University School of Medicine, Hamamatsu, Not set
University of Tokyo, Tokyo, Not set
Hospital Vall d´Hebron, Barcelona, Not set
Acibadem Maslak Hospital, Istanbul, Not set
Conditions: Spinal Fusion
Adapting and Piloting Acceptance and Commitment Therapy (ACT) for Severe Premenstrual Mood Symptoms
Recruiting
In the weeks prior to menstruation, many individuals experience mood and physical symptoms that negatively impact their quality of life and functioning. Approximately 5% of women and menstruating individuals have such severe symptoms that they meet criteria for Premenstrual Dysphoric Disorder (PMDD). Further, of those with underlying mood disorders (i.e., depression, bipolar disorder) about 60% have cyclical worsening of symptoms classified as premenstrual exacerbation (PME). Both PMDD and PME a... Read More
In the weeks prior to menstruation, many individuals experience mood and physical symptoms that negatively impact their quality of life and functioning. Approximately 5% of women and menstruating individuals have such severe symptoms that they meet criteria for Premenstrual Dysphoric Disorder (PMDD). Further, of those with underlying mood disorders (i.e., depression, bipolar disorder) about 60% have cyclical worsening of symptoms classified as premenstrual exacerbation (PME). Both PMDD and PME are associated with significant impairment, yet limited effective options exist to treat these conditions. In this project, the investigators will adapt and evaluate an Acceptance and Commitment Therapy (ACT) group for PMDD and PME, entitled ACT-Premenstrual (ACT-PM), delivered virtually to maximize accessibility. The investigators will examine whether ACT-PM is feasible to deliver and whether it is acceptable to group participants and those facilitating the group. The study will lay the groundwork for future research to determine if the group is effective. If effective, the intervention could be scaled up to improve quality of life and outcomes for individuals suffering from PMDD and PME. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/14/2025
Locations: Women's College Hospital, Toronto, Ontario +1 locations
Women's College Hospital, Toronto, Ontario
Women's College Hospital, Toronto, Ontario
Conditions: Premenstrual Dysphoric Disorder, Premenstrual Exacerbation of Mood Disorder
A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
Recruiting
This study is conducted to confirm whether etavopivat works well at reducing the number of Vaso-occlusive crisis VOCs (sickle cell pain crises) caused by obstructions in blood vessels in adults and adolescents living with sickle cell disease. The study will also evaluate how well etavopivat can reduce the damage to different organs, improve your exercise tolerance and reduce fatigue in people with sickle cell disease.The participants will either get etavopivat or placebo. Which treatment the par... Read More
This study is conducted to confirm whether etavopivat works well at reducing the number of Vaso-occlusive crisis VOCs (sickle cell pain crises) caused by obstructions in blood vessels in adults and adolescents living with sickle cell disease. The study will also evaluate how well etavopivat can reduce the damage to different organs, improve your exercise tolerance and reduce fatigue in people with sickle cell disease.The participants will either get etavopivat or placebo. Which treatment the participants will get is decided by chance. Etavopivat is a new medicine and is currently being tested in other studies in addition to this one. The study will last for about 2 years. Read Less
Gender:
ALL
Ages:
12 years and above
Trial Updated:
07/14/2025
Locations: Uni of Alabama at Birmingham, Birmingham, Alabama +160 locations
Uni of Alabama at Birmingham, Birmingham, Alabama
Univer South Alabama Ped/Onc, Mobile, Alabama
Phoenix Children's Hsptl, Phoenix, Arizona
Arkansas Children's Hospital, Little Rock, Arkansas
Children's Hospital Los Angeles - Endocrinology, Los Angeles, California
UCLA Health, Los Angeles, California
Valley Children's Hospital, Madera, California
University Of California Irvine, Orange, California
Stanford University_Palo Alto, Palo Alto, California
Harbor-UCLA Medical Center, Torrance, California
Clinical and Transl Res Center, Aurora, Colorado
Nemours/AI duPont Hosp-Chld, Wilmington, Delaware
Childrens National Medical Ctr, Washington, District of Columbia
MedStar Hlth Res Institute, Washington, District of Columbia
Memorial Healthcare, Hollywood, Florida
Children's Healthcare Atlanta, Atlanta, Georgia
Childrens Hospital of Chicago, Chicago, Illinois
Univer Of Illinois at Chicago, Chicago, Illinois
Children's Hosp-New Orleans, New Orleans, Louisiana
Boston Children's Hospital, Boston, Massachusetts
Boston Medical Center, Boston, Massachusetts
Henry Ford Hospital_Detroit, Detroit, Michigan
University of Minnesota, Minneapolis, Minnesota
Washington University-St.Louis, Saint Louis, Missouri
Children's Nebraska, Omaha, Nebraska
Cure 4 the Kids Foundation, Las Vegas, Nevada
Newark Beth Israel Medical Center, Newark, New Jersey
Jacobi Medical Center, Bronx, New York
Montefiore Medical Ctr, Bronx, New York
NYC Health+Hospitals, Brooklyn, New York
Interfaith Medical Center, Brooklyn, New York
Northwell Health, Mount Kisco, New York
Cohen Children's Medical Ctr, Queens, New York
Duke Comprehen Sickle Cell, Durham, North Carolina
Duke University Medical Center, Durham, North Carolina
East Carolina Univ-Greenville, Greenville, North Carolina
Atrium Health-Wake Forest Bapt, Winston-Salem, North Carolina
Univ Hosp Cleveland Med Ctr, Cleveland, Ohio
Ohio State Univ Wexner Med Ctr, Columbus, Ohio
Univ of OK Health Sciences Ctr, Oklahoma City, Oklahoma
Children's Hosptl Philadelphia, Philadelphia, Pennsylvania
St Christopher Hosp for Child, Philadelphia, Pennsylvania
Methodist University Hospital, Memphis, Tennessee
St. Jude Children's Res Hosp, Memphis, Tennessee
UT Health University of Texas, Houston, Texas
Inova Health System, Fairfax, Virginia
Children's Hsptl Of The Kings, Norfolk, Virginia
Virginia Comm Univ Medical Ctr, Richmond, Virginia
Mary Bridge Children's Health, Tacoma, Washington
Mary Bridge Children's Health, Tacoma, Washington
Royal Prince Alfred Hospital, Camperdown, New South Wales
Prince of Wales Hospital - Department of Haematology, Randwick, New South Wales
Monash Health, Clayton, Victoria
Fiona Stanley Hospital - Haemophilia and Haemostasis Centre, Murdoch, Western Australia
CHU Saint-Pierre - UMC Sint-Pieter, Bruxelles, Not set
CHU - UVC Brugmann, Bruxelles, Not set
HUB - Hôpital Erasme, Bruxelles, Not set
UZ Antwerpen - UZA - Haematology, Edegem, Not set
UZ Antwerpen - UZA - Kinderhemato-Oncologie, Edegem, Not set
UZ Leuven - Kindergeneeskunde, Leuven, Not set
MultiHemo - Grupo Oncoclínicas, Recife, Pernambuco
HC da FMUSP Hospital das Clínicas São Paulo, São Paulo, SP
Hemocentro UNICAMP, Distrito De Barão Geraldo - Campinas, São Paulo
Fundação Hemocentro de Ribeirão Preto, Ribeirão Preto, São
Hemorio-Fundarj, Rio de Janeiro, Not set
Hospital Samaritano Higienópolis - Instituto de Conhecimento Ensino e Pesquisa (ICEP), São Paulo, Not set
Foothills Med Ctr-Univ Calgary, Calgary, Alberta
Stollery Children's Hospital, Edmonton, Alberta
University of Alberta_Edmonton, Edmonton, Alberta
BC Children's Hospital, Vancouver, British Columbia
LHSC - Victoria Hospital, London, Ontario
UHN-Toronto General Hospital, Toronto, Ontario
University of Toronto, Toronto, Ontario
CHUM-Hosp de Univ Montreal, Montreal, Quebec
Montreal Children's Hospital, Montreal, Quebec
Hospital Pablo Tobon Uribe, Medellin, Antioquia
Clinica de la Costa, Barranquilla, Atlántico
Sociedad de Oncología y Hematología del Cesar SAS (SOHEC), Valledupar, Cesar
Clínica IMAT Oncomedica Auna S.A.S., Monteria, Córdoba
Centro de investigaciones clínicas, fudación valle del lili, Cali, Valle Del Cauca
Sociedad de Oncología y Hematología del Cesar SAS (SOHEC), Antioquia, Not set
Centro de investigaciones clínicas, fudación valle del lili, Cali, Not set
Clínica IMAT Oncomedica Auna S.A.S., Monteria, Not set
Ap-Hp-Hopital Avicenne, Bobigny, Not set
Centre Hospitalier Universitaire de Bordeaux-Hopital Pellegrin, Bordeaux, Not set
Ap-Hp-Hopital Henri Mondor, Créteil, Not set
Centre Hospitalier Universitaire Grenoble Alpes-Site Nord Michallon-1, Grenoble cedex 9, Not set
Hospices Civils de Lyon-Hopital Edouard Herriot, Lyon Cedex 03, Not set
Ap-Hp-Hopital Necker-1, Paris, Not set
Ap-Hp-Hopital Robert Debre, Paris, Not set
Centre Hospitalier Universitaire de Rouen-Hopital Charles Nicolle, Rouen cedex, Not set
Agogo Presbyterian Hospital, Ghana, Agogo, Not set
Kintampo Health Research Centre (KHRC), Kintampo, Ghana, Kintampo, Not set
Navrongo Health Research Centre, Ghana, Navrongo, Not set
"Laiko" General Hospital of Athens, Athens, Not set
Childrens' Hospital of Athens "Agia Sofia", Athens, Not set
Hippokration Hospital, Athens, Not set
University General Hospital Of Ioannina, Ioannina, Not set
"AHEPA" University General Hospital of Thessaloniki, Thessaloniki, Not set
Gauhati Medical College and Hospital, Guwahati, Assam
All India Institute of Medical Sciences (AIIMS), Raipur, Raipur, Chhattisgarh
Zydus Medical College & Hospital, Dahod, Gujarat
Nirmal Hospital Pvt. Ltd., Surat, Gujarat
SSG Hospital, Baroda, Vadodara, Gujarat
HOCC Haemato Oncology Care Centre, Vadodara, Gujarat
JSS Hospital, Mysore, Mysuru, Karnataka
Government Medical College, Kozhikode, Kozhikode, Kerala
Arihant Multispeciality Hospital, Nagpur, Maharashtra
IMS and SUM Hospital, Bhubaneswar, Orissa
RNT Medical College, Udaipur, Rajasthan
NIZAM'S Institute of Medical Sciences, Hyderabad, Telangana
Post Graduate Institute of Child Health, Noida, Uttar Pradesh
All India Institute of Medical Sciences_New Dehli, New Delhi, Not set
Azienda Ospedaliera Universitaria San Luigi Gonzaga, Orbassano, Torino
ASST Civili di Brescia, Brescia, Not set
ARNAS (Azienda Ospedaliera di Rilievo Nazionale di Alta Specializzazione) Ospedale Garibaldi, Catania, Not set
A.O. Universitaria di Modena, Modena, Not set
Fondazione IRCCS San Gerardo dei Tintori, Monza, Not set
A.O.U. Università Studi della Campania "Luigi Vanvitelli", Naples, Not set
Azienda Ospedale Universita Padova, Padova, Not set
Azienda Ospedaliera Ospedali Riuniti Villa Sofia - Cervello, Palermo, Not set
Policlinico GB Rossi, Verona, Not set
Ahero Clinical Trials Unit, Kisumu, Kenya, Kisumu, Not set
Gertrude's Children's Hospital, Nairobi, Nairobi, Not set
KEMRI Siaya Clinical Research Annex Siaya County Referral Hospital, Siaya, Siaya, Not set
International Cancer Institute (ICI), Uasin Gishu County, Not set
American University of Beirut Medical Centre, Hamra, Not set
Hospital Nini, Tripoli, Not set
Amsterdam UMC Lokatie VUMC, Amsterdam, Not set
Haga Ziekenhuis, Den Haag, Not set
Erasmus MC, Rotterdam, Not set
UMC Utrecht, Van Creveldkliniek, Utrecht, Not set
University College Hospital Paediatric Haematology and Oncology Unit, Ibadan, Ibadan, Oyo State
Centre for Sickle Cell Disease Research and Training University of Abuja (CESRTA), Abuja, Abuja, Not set
University of Nigeria Teaching Hospital, Enugu, Enugu, Not set
Lagos University Teaching Hospital, Lagos, Lagos, Not set
The Royal Hospital, Muscat, Not set
Sultan Qaboos University Hospital, Muscat, Not set
King Abdulaziz Hospital-Al Ahsa-National Guard, Al Ahsa, Not set
National Guard Hospital Dammam, Dhahran, Not set
King Faisal Specialist Hospital & Research Centre, Riyadh, Riyadh, Not set
Hospital Vall d'Hebron, Barcelona, Not set
Hospital Gregorio Marañón, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Hospital Universitario Virgen del Rocío, Sevilla, Not set
Acibadem Adana Hastanesi, Adana, Not set
Baskent Universitesi Adana, Adana, Not set
Cukurova University Medical Faculty, Adana, Not set
Hacettepe University Hematology, Ankara, Not set
Mersin University Medical Faculty Pediatric Hematology, Mersin, Not set
Mersin University Medical Faculty Pediatric Hematology, Mersin, Not set
VM Medical Park Mersin Hospital, Mersin, Not set
Jinja Regional Referral Hospital Children's Ward, Jinja, Not set
Makerere University College of Health Sciences, Kampala, Not set
Joint Clinical Research Centre (JCRC), Kampala, Not set
Addenbrooke's Hospital, Cambridge, Not set
Whittington Hospital, London, Not set
Guy's Hospital, London, Not set
Kings College Hospital, London, Not set
Kings College Hospital, London, Not set
Imperial College London, London, Not set
Conditions: Sickle Cell Disease
A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-PD1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma
Recruiting
This study is researching an experimental drug called REGN3767, also known as fianlimab (R3767), when combined with another medication called cemiplimab (each individually called a "study drug" or called "study drugs" when combined) compared with cemiplimab alone. These types of immunotherapy study drugs are collectively known as immune checkpoint inhibitors. Immunotherapies are treatments that use the immune system to recognize and kill cancer cells. The study is focused on participants with a... Read More
This study is researching an experimental drug called REGN3767, also known as fianlimab (R3767), when combined with another medication called cemiplimab (each individually called a "study drug" or called "study drugs" when combined) compared with cemiplimab alone. These types of immunotherapy study drugs are collectively known as immune checkpoint inhibitors. Immunotherapies are treatments that use the immune system to recognize and kill cancer cells. The study is focused on participants with a type of skin cancer known as melanoma.
The objective of this study is to see if the combination of fianlimab and cemiplimab is an effective treatment compared to cemiplimab in participants with high-risk, resectable melanoma. Participants will receive treatment before surgery, undergo resection, and then will have the option to continue treatment after resection.
The study is looking at several other research questions, including:
* What side effects may happen from receiving the study drug(s).
* How much study drug(s) is in the blood at different times.
* Whether the body makes antibodies against the study drug(s) (which could make the drug less effective or could lead to side effects). Antibodies are proteins that are naturally found in the blood stream that fight infections.
* How administering the study drugs might improve quality of life. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/14/2025
Locations: UC San Diego, La Jolla, California +49 locations
UC San Diego, La Jolla, California
Usc Norris Comprehensive Cancer Center, Los Angeles, California
Hoag Family Cancer Institute, Newport Beach, California
California Pacific Medical Center Research Institute, San Francisco, California
University of California San Francisco (UCSF), San Francisco, California
St John's Cancer Institute, Santa Monica, California
Hartford Hospital, Hartford, Connecticut
Emory Healthcare, Emory Clinic, Atlanta, Georgia
NorthShore University HealthSystem, Evanston, Illinois
University of Massachusetts Chan Medical School, Worcester, Massachusetts
Washington University School of Medicine, Saint Louis, Missouri
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Northwell Health Cancer Institute, Lake Success, New York
Duke Cancer Institute, University Hospital, Durham, North Carolina
Seidman Cancer Center, Cleveland, Ohio
Cleveland Clinic Foundation, Cleveland, Ohio
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
University of Tennessee Medical Center, Knoxville, Tennessee
University of Texas MD Anderson Cancer Center, Houston, Texas
University of Virginia, Charlottesville, Virginia
Lismore Base Hospital, Lismore, New South Wales
Westmead Hospital, Westmead, New South Wales
Melanoma Institute of Australia, Wollstonecraft, New South Wales
Hervey Bay Hospital, Hervey Bay, Queensland
The Queen Elizabeth Hospital, Woodville, South Australia
Eastern Health, Box Hill, Victoria
Peter MacCallum Cancer Centre, Melbourne, Victoria
One Clinical Research at Hollywood Private Hospital, Nedlands, Western Australia
Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal, Quebec
CHU de Quebec - Universite Laval, Quebec City, Quebec
CHU-Dijon, Dijon, Burgundy
CHRU de Tours, Tours, Centre Val De Loire
Chu De Bordeaux, Bordeaux, Gironde
Saint Louis Hospital, Paris, Ile De France
Gustave Roussy, Villejuif, Ile De France
Centre Francois Baclesse, Caen, Normandy
Hopital Ambroise Pare, Boulogne, Not set
CHU Estaing, Clermont Ferrand, Not set
Regional University Hospital of Lille 2208, Lille, Not set
Hopital Timone, Marseille, Not set
Centre Hospitalier Universitaire De Nice Hopital De L Archet, Nice, Not set
University Hospital Giessen, Giessen, Hessen
Universitatsklinikum Leipzig, AoR, Leipzig, Saxony
Charite University Medicine, Berlin, Not set
Azienda Ospedaliero-Universitaria Ferrara, Cona, Ferrara
U.O. Oncologia Medica 2 Universitaria, Azienda Ospedaliero Universitaria Pisana, Pisa, Not set
Instituto Oncologico Dr Rosell, Barcelona, Catalunya
Vall d'Hebron Hospital, Barcelona, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
Hospital Clinico Universitario de Salamanca, Salamanca, Not set
Conditions: Melanoma
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-small Cell Lung Cancer
Recruiting
This phase III trial compares the effect of adding stereotactic body radiation therapy (SBRT) to the usual treatment (conventional image guided radiation therapy \[IGRT\] and chemotherapy followed by immunotherapy with durvalumab or osimertinib) versus the usual treatment alone in treating patients with non-small cell lung cancer that has spread to nearby tissue or lymph nodes (locally advanced) and cannot be treated by surgery (inoperable). SBRT uses special equipment to position a patient and... Read More
This phase III trial compares the effect of adding stereotactic body radiation therapy (SBRT) to the usual treatment (conventional image guided radiation therapy \[IGRT\] and chemotherapy followed by immunotherapy with durvalumab or osimertinib) versus the usual treatment alone in treating patients with non-small cell lung cancer that has spread to nearby tissue or lymph nodes (locally advanced) and cannot be treated by surgery (inoperable). SBRT uses special equipment to position a patient and deliver radiation to tumors with high precision. This method may kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue. IGRT is a type of radiation that uses a computer to create a picture of the tumor, to help guide the radiation beam during therapy, making it more accurate and causing less damage to healthy tissue. Usual chemotherapy used in this trial consists of combinations of the following drugs: cisplatin, carboplatin, paclitaxel, nab-paclitaxel, pemetrexed, and etoposide. Cisplatin and carboplatin are in a class of medications known as platinum-containing compounds. Cisplatin works by killing, stopping, or slowing the growth of tumor cells. Carboplatin works in a way similar to the anticancer drug cisplatin but may be better tolerated than cisplatin. Carboplatin works by killing, stopping, or slowing the growth of tumor cells as well. Paclitaxel is in a class of medications called antimicrotubule agents. It works by stopping the growth and spread of tumor cells. Nab-paclitaxel is an albumin-stabilized nanoparticle formulation of paclitaxel which may have fewer side effects and work better than other forms of paclitaxel. Pemetrexed is in a class of medications called antifolate antineoplastic agents. It works by blocking the action of a certain substance in the body that may help tumor cells multiply. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and deoxyribonucleic acid (DNA) repair and may kill tumor cells. Immunotherapy with durvalumab, may induce changes in the body's immune system and may interfere with the ability of tumor cells to grow and spread. Osimertinib is in a class of medications called kinase inhibitors. It works by blocking the action of a protein called EGFR that signals cancer cells to multiply. This helps slow or stop the spread of tumor cells. Adding SBRT to the usual treatment of IGRT with chemotherapy and immunotherapy may be more effective at treating patients with locally-advanced non-small cell lung cancer than giving the usual treatment alone. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/14/2025
Locations: Kingman Regional Medical Center, Kingman, Arizona +413 locations
Kingman Regional Medical Center, Kingman, Arizona
Cancer Center at Saint Joseph's, Phoenix, Arizona
Mayo Clinic Hospital in Arizona, Phoenix, Arizona
Banner University Medical Center - Tucson, Tucson, Arizona
University of Arizona Cancer Center-North Campus, Tucson, Arizona
University of Arkansas for Medical Sciences, Little Rock, Arkansas
AIS Cancer Center at San Joaquin Community Hospital, Bakersfield, California
Mills-Peninsula Medical Center, Burlingame, California
Palo Alto Medical Foundation-Fremont, Fremont, California
Los Angeles General Medical Center, Los Angeles, California
USC / Norris Comprehensive Cancer Center, Los Angeles, California
Fremont - Rideout Cancer Center, Marysville, California
Memorial Medical Center, Modesto, California
Palo Alto Medical Foundation-Camino Division, Mountain View, California
Palo Alto Medical Foundation Health Care, Palo Alto, California
Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California
Sutter Roseville Medical Center, Roseville, California
Sutter Medical Center Sacramento, Sacramento, California
California Pacific Medical Center-Pacific Campus, San Francisco, California
Mills Health Center, San Mateo, California
Sutter Pacific Medical Foundation, Santa Rosa, California
Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California
Sutter Solano Medical Center/Cancer Center, Vallejo, California
UCHealth University of Colorado Hospital, Aurora, Colorado
Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado
UCHealth Memorial Hospital Central, Colorado Springs, Colorado
Memorial Hospital North, Colorado Springs, Colorado
UCHealth - Cherry Creek, Denver, Colorado
Poudre Valley Hospital, Fort Collins, Colorado
Cancer Care and Hematology-Fort Collins, Fort Collins, Colorado
UCHealth Greeley Hospital, Greeley, Colorado
UCHealth Highlands Ranch Hospital, Highlands Ranch, Colorado
UCHealth Lone Tree Health Center, Lone Tree, Colorado
Medical Center of the Rockies, Loveland, Colorado
Beebe Medical Center, Lewes, Delaware
Beebe South Coastal Health Campus, Millville, Delaware
Helen F Graham Cancer Center, Newark, Delaware
Medical Oncology Hematology Consultants PA, Newark, Delaware
Christiana Care Health System-Christiana Hospital, Newark, Delaware
Beebe Health Campus, Rehoboth Beach, Delaware
Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware
Morton Plant Hospital, Clearwater, Florida
Halifax Health Medical Center-Centers for Oncology, Daytona Beach, Florida
Mayo Clinic in Florida, Jacksonville, Florida
Jupiter Medical Center, Jupiter, Florida
Orlando Health Cancer Institute, Orlando, Florida
Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida
Winter Haven Hospital, Winter Haven, Florida
Grady Health System, Atlanta, Georgia
Emory Proton Therapy Center, Atlanta, Georgia
Emory University Hospital Midtown, Atlanta, Georgia
Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia
Emory Saint Joseph's Hospital, Atlanta, Georgia
Augusta University Medical Center, Augusta, Georgia
WellStar Cobb Hospital, Austell, Georgia
Hamilton Medical Center - Peeples Cancer Institute, Dalton, Georgia
Wellstar Kennestone Hospital, Marietta, Georgia
CTCA at Southeastern Regional Medical Center, Newnan, Georgia
Hawaii Cancer Care - Westridge, 'Aiea, Hawaii
Pali Momi Medical Center, 'Aiea, Hawaii
Hawaii Cancer Care Inc - Waterfront Plaza, Honolulu, Hawaii
Queen's Cancer Cenrer - POB I, Honolulu, Hawaii
Queen's Medical Center, Honolulu, Hawaii
Straub Clinic and Hospital, Honolulu, Hawaii
University of Hawaii Cancer Center, Honolulu, Hawaii
Kuakini Medical Center, Honolulu, Hawaii
Queen's Cancer Center - Kuakini, Honolulu, Hawaii
The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii
Alton Memorial Hospital, Alton, Illinois
Rush - Copley Medical Center, Aurora, Illinois
Advocate Outpatient Center - Aurora, Aurora, Illinois
Advocate Good Shepherd Hospital, Barrington, Illinois
OSF Saint Joseph Medical Center, Bloomington, Illinois
Illinois CancerCare-Bloomington, Bloomington, Illinois
Illinois CancerCare-Canton, Canton, Illinois
Illinois CancerCare-Carthage, Carthage, Illinois
Centralia Oncology Clinic, Centralia, Illinois
Northwestern University, Chicago, Illinois
Advocate Illinois Masonic Medical Center, Chicago, Illinois
AMG Crystal Lake - Oncology, Crystal Lake, Illinois
Carle at The Riverfront, Danville, Illinois
Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois
Decatur Memorial Hospital, Decatur, Illinois
Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois
Advocate Good Samaritan Hospital, Downers Grove, Illinois
Carle Physician Group-Effingham, Effingham, Illinois
Crossroads Cancer Center, Effingham, Illinois
Advocate Sherman Hospital, Elgin, Illinois
Illinois CancerCare-Eureka, Eureka, Illinois
Illinois CancerCare-Galesburg, Galesburg, Illinois
Northwestern Medicine Cancer Center Delnor, Geneva, Illinois
Advocate South Suburban Hospital, Hazel Crest, Illinois
Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois
AMG Libertyville - Oncology, Libertyville, Illinois
Condell Memorial Hospital, Libertyville, Illinois
Illinois CancerCare-Macomb, Macomb, Illinois
Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois
Cancer Care Center of O'Fallon, O'Fallon, Illinois
HSHS Saint Elizabeth's Hospital, O'Fallon, Illinois
Advocate Christ Medical Center, Oak Lawn, Illinois
Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois
Advocate High Tech Medical Park, Palos Heights, Illinois
Advocate Lutheran General Hospital, Park Ridge, Illinois
Illinois CancerCare-Pekin, Pekin, Illinois
Illinois CancerCare-Peoria, Peoria, Illinois
OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Peoria, Illinois
Methodist Medical Center of Illinois, Peoria, Illinois
OSF Saint Francis Medical Center, Peoria, Illinois
Illinois CancerCare-Peru, Peru, Illinois
Illinois CancerCare-Princeton, Princeton, Illinois
UW Health Carbone Cancer Center Rockford, Rockford, Illinois
Memorial Hospital East, Shiloh, Illinois
Southern Illinois University School of Medicine, Springfield, Illinois
Springfield Clinic, Springfield, Illinois
Springfield Memorial Hospital, Springfield, Illinois
Carle Cancer Center, Urbana, Illinois
Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois
Illinois CancerCare - Washington, Washington, Illinois
Midwestern Regional Medical Center, Zion, Illinois
Mary Greeley Medical Center, Ames, Iowa
McFarland Clinic - Ames, Ames, Iowa
UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa
Saint Luke's Hospital, Cedar Rapids, Iowa
UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive, Iowa
Heartland Oncology and Hematology LLP, Council Bluffs, Iowa
Methodist Jennie Edmundson Hospital, Council Bluffs, Iowa
Iowa Methodist Medical Center, Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Waukee Clinic, Waukee, Iowa
University of Kansas Cancer Center, Kansas City, Kansas
The University of Kansas Cancer Center - Olathe, Olathe, Kansas
University of Kansas Cancer Center-Overland Park, Overland Park, Kansas
Salina Regional Health Center, Salina, Kansas
University of Kansas Health System Saint Francis Campus, Topeka, Kansas
University of Kansas Hospital-Westwood Cancer Center, Westwood, Kansas
Ascension Via Christi Hospitals Wichita, Wichita, Kansas
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
Louisiana State University Health Science Center, New Orleans, Louisiana
University Medical Center New Orleans, New Orleans, Louisiana
MaineHealth Maine Medical Center - Portland, Portland, Maine
MaineHealth Cancer Care Center of York County, Sanford, Maine
MaineHealth Maine Medical Center- Scarborough, Scarborough, Maine
MaineHealth Cancer Care and IV Therapy - South Portland, South Portland, Maine
Luminis Health Anne Arundel Medical Center, Annapolis, Maryland
Greater Baltimore Medical Center, Baltimore, Maryland
Sinai Hospital of Baltimore, Baltimore, Maryland
TidalHealth Richard A Henson Cancer Institute, Ocean Pines, Maryland
TidalHealth Peninsula Regional, Salisbury, Maryland
William E Kahlert Regional Cancer Center/Sinai Hospital, Westminster, Maryland
UMass Memorial Medical Center - University Campus, Worcester, Massachusetts
Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan
McLaren Cancer Institute-Bay City, Bay City, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan
Trinity Health Medical Center - Brighton, Brighton, Michigan
Chelsea Hospital, Chelsea, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan
McLaren Cancer Institute-Clarkston, Clarkston, Michigan
Michigan Healthcare Professionals Clarkston, Clarkston, Michigan
Wayne State University/Karmanos Cancer Institute, Detroit, Michigan
Michigan Healthcare Professionals Farmington, Farmington Hills, Michigan
Weisberg Cancer Treatment Center, Farmington Hills, Michigan
Corewell Health Farmington Hills Hospital, Farmington Hills, Michigan
McLaren Cancer Institute-Flint, Flint, Michigan
Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan
Bronson Methodist Hospital, Kalamazoo, Michigan
West Michigan Cancer Center, Kalamazoo, Michigan
Ascension Borgess Hospital, Kalamazoo, Michigan
Karmanos Cancer Institute at McLaren Greater Lansing, Lansing, Michigan
University of Michigan Health - Sparrow Lansing, Lansing, Michigan
McLaren Cancer Institute-Lapeer Region, Lapeer, Michigan
Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan
Michigan Healthcare Professionals Macomb, Macomb, Michigan
Michigan Healthcare Professionals Madison Heights, Madison Heights, Michigan
McLaren Cancer Institute-Macomb, Mount Clemens, Michigan
McLaren Cancer Institute-Northern Michigan, Petoskey, Michigan
Michigan Healthcare Professionals Pontiac, Pontiac, Michigan
Trinity Health Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan
McLaren-Port Huron, Port Huron, Michigan
Corewell Health William Beaumont University Hospital, Royal Oak, Michigan
Munson Medical Center, Traverse City, Michigan
Corewell Health Beaumont Troy Hospital, Troy, Michigan
Michigan Healthcare Professionals Troy, Troy, Michigan
Henry Ford Health Warren Hospital, Warren, Michigan
University of Michigan Health - West, Wyoming, Michigan
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan
Sanford Joe Lueken Cancer Center, Bemidji, Minnesota
Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota
Essentia Health - Deer River Clinic, Deer River, Minnesota
Essentia Health Cancer Center, Duluth, Minnesota
Essentia Health Saint Mary's Medical Center, Duluth, Minnesota
Miller-Dwan Hospital, Duluth, Minnesota
Essentia Health Hibbing Clinic, Hibbing, Minnesota
Mayo Clinic in Rochester, Rochester, Minnesota
Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota
Essentia Health Sandstone, Sandstone, Minnesota
Essentia Health Virginia Clinic, Virginia, Minnesota
Baptist Memorial Hospital and Cancer Center-Desoto, Southhaven, Mississippi
Saint Francis Medical Center, Cape Girardeau, Missouri
Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri
Parkland Health Center - Farmington, Farmington, Missouri
Freeman Health System, Joplin, Missouri
University of Kansas Cancer Center - North, Kansas City, Missouri
University of Kansas Cancer Center - Lee's Summit, Lee's Summit, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Mercy Hospital South, Saint Louis, Missouri
Siteman Cancer Center-South County, Saint Louis, Missouri
Missouri Baptist Medical Center, Saint Louis, Missouri
Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri
Mercy Hospital Saint Louis, Saint Louis, Missouri
Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri
Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri
Mercy Hospital Springfield, Springfield, Missouri
Missouri Baptist Sullivan Hospital, Sullivan, Missouri
BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri
Billings Clinic Cancer Center, Billings, Montana
Bozeman Health Deaconess Hospital, Bozeman, Montana
Benefis Sletten Cancer Institute, Great Falls, Montana
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC, Omaha, Nebraska
Nebraska Methodist Hospital, Omaha, Nebraska
Oncology Associates PC, Omaha, Nebraska
Renown Regional Medical Center, Reno, Nevada
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire
Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey
Cooper Hospital University Medical Center, Camden, New Jersey
The Cancer Institute of New Jersey Hamilton, Hamilton, New Jersey
Jersey City Medical Center, Jersey City, New Jersey
Monmouth Medical Center Southern Campus, Lakewood, New Jersey
Saint Barnabas Medical Center, Livingston, New Jersey
Monmouth Medical Center, Long Branch, New Jersey
Memorial Sloan Kettering Monmouth, Middletown, New Jersey
Memorial Sloan Kettering Bergen, Montvale, New Jersey
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Rutgers New Jersey Medical School, Newark, New Jersey
Robert Wood Johnson University Hospital Somerset, Somerville, New Jersey
Community Medical Center, Toms River, New Jersey
Presbyterian Kaseman Hospital, Albuquerque, New Mexico
Presbyterian Rust Medical Center/Jorgensen Cancer Center, Rio Rancho, New Mexico
Wilmot Cancer Center at Batavia, Batavia, New York
Montefiore Medical Center-Einstein Campus, Bronx, New York
Montefiore Medical Center-Weiler Hospital, Bronx, New York
Montefiore Medical Center - Moses Campus, Bronx, New York
Sands Cancer Center, Canandaigua, New York
Memorial Sloan Kettering Commack, Commack, New York
Glens Falls Hospital, Glens Falls, New York
Memorial Sloan Kettering Westchester, Harrison, New York
New York Proton Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, New York
Wilmot Cancer Institute Radiation Oncology at Greece, Rochester, New York
Highland Hospital, Rochester, New York
University of Rochester, Rochester, New York
Stony Brook University Medical Center, Stony Brook, New York
State University of New York Upstate Medical University, Syracuse, New York
Memorial Sloan Kettering Nassau, Uniondale, New York
Westchester Medical Center, Valhalla, New York
Wilmot Cancer Institute at Webster, Webster, New York
Atrium Health Stanly/LCI-Albemarle, Albemarle, North Carolina
Duke Cancer Center Cary, Cary, North Carolina
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina
Novant Health Presbyterian Medical Center, Charlotte, North Carolina
Atrium Health Pineville/LCI-Pineville, Charlotte, North Carolina
Atrium Health University City/LCI-University, Charlotte, North Carolina
Wake Forest University at Clemmons, Clemmons, North Carolina
Atrium Health Cabarrus/LCI-Concord, Concord, North Carolina
Duke University Medical Center, Durham, North Carolina
Levine Cancer Institute - Rutherford, Forest City, North Carolina
CaroMont Regional Medical Center, Gastonia, North Carolina
Novant Health Cancer Institute - Huntersville, Huntersville, North Carolina
Novant Health Presbyterian Medical Center Huntersville, Huntersville, North Carolina
Novant Health Cancer Institute - Kernersville, Kernersville, North Carolina
Levine Cancer Institute - Union West, Matthews, North Carolina
Matthews Radiation Oncology Center, Matthews, North Carolina
Novant Health Cancer Institute - Matthews, Matthews, North Carolina
Atrium Health Union/LCI-Union, Monroe, North Carolina
Novant Health Cancer Institute - Mooresville, Mooresville, North Carolina
Novant Health Cancer Institute - Mount Airy, Mount Airy, North Carolina
Novant Health Cancer Institute - Wilkesboro, North Wilkesboro, North Carolina
Duke Cancer Center Raleigh, Raleigh, North Carolina
Novant Health Cancer Institute - Rowan, Salisbury, North Carolina
Rowan Regional Medical Center, Salisbury, North Carolina
Atrium Health Cleveland/LCI-Cleveland, Shelby, North Carolina
Novant Health Cancer Institute - Statesville, Statesville, North Carolina
Wake Forest Baptist Health - Hematology Oncology - Statesville, Statesville, North Carolina
Novant Cancer Institute Radiation Oncology - Supply, Supply, North Carolina
Novant Health Cancer Institute - Thomasville, Thomasville, North Carolina
Wake Forest Baptist Health - Wilkes Medical Center, Wilkesboro, North Carolina
Novant Health Cancer Institute Radiation Oncology - Wilmington, Wilmington, North Carolina
Novant Health New Hanover Regional Medical Center, Wilmington, North Carolina
Novant Health Forsyth Medical Center, Winston-Salem, North Carolina
Wake Forest University Health Sciences, Winston-Salem, North Carolina
Sanford Bismarck Medical Center, Bismarck, North Dakota
Sanford Broadway Medical Center, Fargo, North Dakota
Sanford Roger Maris Cancer Center, Fargo, North Dakota
Altru Cancer Center, Grand Forks, North Dakota
Cleveland Clinic Akron General, Akron, Ohio
UH Seidman Cancer Center at UH Avon Health Center, Avon, Ohio
UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio
Cleveland Clinic Mercy Hospital, Canton, Ohio
Aultman Health Foundation, Canton, Ohio
Miami Valley Hospital South, Centerville, Ohio
University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio
Case Western Reserve University, Cleveland, Ohio
Riverside Methodist Hospital, Columbus, Ohio
Grant Medical Center, Columbus, Ohio
Doctors Hospital, Columbus, Ohio
Miami Valley Hospital, Dayton, Ohio
Premier Blood and Cancer Center, Dayton, Ohio
Dayton Physician LLC - Englewood, Dayton, Ohio
Miami Valley Hospital North, Dayton, Ohio
Delaware Health Center-Grady Cancer Center, Delaware, Ohio
Grady Memorial Hospital, Delaware, Ohio
Dublin Methodist Hospital, Dublin, Ohio
Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio
Miami Valley Cancer Care and Infusion, Greenville, Ohio
OhioHealth Mansfield Hospital, Mansfield, Ohio
OhioHealth Marion General Hospital, Marion, Ohio
UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio
Mercy Health - Perrysburg Hospital, Perrysburg, Ohio
Upper Valley Medical Center, Troy, Ohio
University of Cincinnati Cancer Center-West Chester, West Chester, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Legacy Mount Hood Medical Center, Gresham, Oregon
Legacy Good Samaritan Hospital and Medical Center, Portland, Oregon
Legacy Meridian Park Hospital, Tualatin, Oregon
Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania
Chambersburg Hospital, Chambersburg, Pennsylvania
Geisinger Medical Center, Danville, Pennsylvania
Ephrata Cancer Center, Ephrata, Pennsylvania
Adams Cancer Center, Gettysburg, Pennsylvania
Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania
Lancaster General Ann B Barshinger Cancer Institute, Lancaster, Pennsylvania
Sechler Family Cancer Center, Lebanon, Pennsylvania
Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania
University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
Reading Hospital, West Reading, Pennsylvania
Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania
Asplundh Cancer Pavilion, Willow Grove, Pennsylvania
Lankenau Medical Center, Wynnewood, Pennsylvania
WellSpan Health-York Cancer Center, York, Pennsylvania
WellSpan Health-York Hospital, York, Pennsylvania
Gibbs Cancer Center-Gaffney, Gaffney, South Carolina
Gibbs Cancer Center-Pelham, Greer, South Carolina
Lancaster Radiation Therapy Center, Lancaster, South Carolina
Rock Hill Radiation Therapy Center, Rock Hill, South Carolina
Levine Cancer Institute-Rock Hill, Rock Hill, South Carolina
Spartanburg Medical Center, Spartanburg, South Carolina
SMC Center for Hematology Oncology Union, Union, South Carolina
Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota
Baptist Memorial Hospital and Cancer Center-Collierville, Collierville, Tennessee
Baptist Memorial Hospital and Cancer Center-Memphis, Memphis, Tennessee
MD Anderson in The Woodlands, Conroe, Texas
M D Anderson Cancer Center, Houston, Texas
MD Anderson West Houston, Houston, Texas
MD Anderson League City, League City, Texas
MD Anderson in Sugar Land, Sugar Land, Texas
Central Vermont Medical Center/National Life Cancer Treatment, Berlin, Vermont
University of Vermont Medical Center, Burlington, Vermont
University of Vermont and State Agricultural College, Burlington, Vermont
Dartmouth Cancer Center - North, Saint Johnsbury, Vermont
Legacy Cancer Institute Medical Oncology and Day Treatment, Vancouver, Washington
Legacy Salmon Creek Hospital, Vancouver, Washington
Edwards Comprehensive Cancer Center, Huntington, West Virginia
West Virginia University Healthcare, Morgantown, West Virginia
Langlade Hospital and Cancer Center, Antigo, Wisconsin
Duluth Clinic Ashland, Ashland, Wisconsin
Northwest Wisconsin Cancer Center, Ashland, Wisconsin
Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin
HSHS Sacred Heart Hospital, Eau Claire, Wisconsin
Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin
Aurora Health Care Germantown Health Center, Germantown, Wisconsin
Aurora Cancer Care-Grafton, Grafton, Wisconsin
Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin
Aurora BayCare Medical Center, Green Bay, Wisconsin
Essentia Health-Hayward Clinic, Hayward, Wisconsin
University of Wisconsin Carbone Cancer Center - Johnson Creek, Johnson Creek, Wisconsin
Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin
William S Middleton VA Medical Center, Madison, Wisconsin
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin
University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin
Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin
Marshfield Medical Center-Marshfield, Marshfield, Wisconsin
Froedtert Menomonee Falls Hospital, Menomonee Falls, Wisconsin
Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin
Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin
Medical College of Wisconsin, Milwaukee, Wisconsin
Aurora Sinai Medical Center, Milwaukee, Wisconsin
Zablocki Veterans Administration Medical Center, Milwaukee, Wisconsin
Marshfield Medical Center - Minocqua, Minocqua, Wisconsin
ProHealth D N Greenwald Center, Mukwonago, Wisconsin
Drexel Town Square Health Center, Oak Creek, Wisconsin
ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin
Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin
Aurora Cancer Care-Racine, Racine, Wisconsin
Aspirus Cancer Care - James Beck Cancer Center, Rhinelander, Wisconsin
Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin
Saint Vincent Hospital Cancer Center at Sheboygan, Sheboygan, Wisconsin
Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin
Essentia Health-Spooner Clinic, Spooner, Wisconsin
Aspirus Cancer Care - Stevens Point, Stevens Point, Wisconsin
Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin
Saint Vincent Hospital Cancer Center at Sturgeon Bay, Sturgeon Bay, Wisconsin
Aurora Medical Center in Summit, Summit, Wisconsin
Essentia Health Saint Mary's Hospital - Superior, Superior, Wisconsin
UW Cancer Center at ProHealth Care, Waukesha, Wisconsin
Aspirus Regional Cancer Center, Wausau, Wisconsin
Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin
Aurora West Allis Medical Center, West Allis, Wisconsin
Froedtert West Bend Hospital/Kraemer Cancer Center, West Bend, Wisconsin
Marshfield Medical Center - Weston, Weston, Wisconsin
Aspirus Cancer Care - Wisconsin Rapids, Wisconsin Rapids, Wisconsin
Ottawa Hospital and Cancer Center-General Campus, Ottawa, Ontario
Conditions: Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8
Evaluation of the Optilume BPH Catheter System and the Rezum Water Vapor Therapy in Treating Benign Prostatic Hyperplasia
Recruiting
Lower urinary symptoms (LUTS) affect older men and their frequency and severity increase with age. According to Berry et al., the histological diagnosis of benign prostatic hyperplasia (BPH) increases from 25% in the group age between 40 to 49 years to 80% in the group age between 70 to 79 years (1). However, this hyperplasia can lead to a bladder outlet obstruction (BOO) secondary to benign prostatic enlargement (BPE), causing storage and voiding symptoms, associated with a considerable impairm... Read More
Lower urinary symptoms (LUTS) affect older men and their frequency and severity increase with age. According to Berry et al., the histological diagnosis of benign prostatic hyperplasia (BPH) increases from 25% in the group age between 40 to 49 years to 80% in the group age between 70 to 79 years (1). However, this hyperplasia can lead to a bladder outlet obstruction (BOO) secondary to benign prostatic enlargement (BPE), causing storage and voiding symptoms, associated with a considerable impairment of the quality of life (2).
Surgical therapy of BPH has continuously evolved in recent years. The current gold standard for the endoscopic treatment of BPH is the transurethral resection of the prostate (TURP). Other innovative techniques were developed including Urolift, transurethral laser enucleation (holmium, thulium) and Aquablation therapy. One of the latest technologies for the management of BPH are Optilume BPH Catheter System (Optilume®, Urotronic Inc, Minneapolis, USA) and Rezum Water Vapor Therapy (Rezum System, Bostocn Scientific, Marlborough, MA).
The purpose of the present study is to compare between patient experience, symptom relief and functional improvement when using the Optilume BPH Catheter System (Optilume®, Urotronic Inc, Minneapolis, USA) and Rezum Water Vapor Therapy (Rezum System, Boston Scientific, Marlborough, MA). Read Less
Gender:
MALE
Ages:
18 years and above
Trial Updated:
07/14/2025
Locations: Centre Hospitalier de l'université de Montréal (CHUM), Montréal, Quebec
Centre Hospitalier de l'université de Montréal (CHUM), Montréal, Quebec
Conditions: Benign Prostatic Hyperplasia (BPH), Lower Urinary Track Symptoms
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability
Recruiting
This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. Stereotactic radiosurgery is a specialized radiation therapy that delivers a single, high dose of radiation directly to the tumor and may cause less damage to normal tissue. Whole brain radiation therapy delivers a low dose of radiat... Read More
This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. Stereotactic radiosurgery is a specialized radiation therapy that delivers a single, high dose of radiation directly to the tumor and may cause less damage to normal tissue. Whole brain radiation therapy delivers a low dose of radiation to the entire brain including the normal brain tissue. Hippocampal avoidance during whole-brain radiation therapy (HA-WBRT) decreases the amount of radiation that is delivered to the hippocampus which is a brain structure that is important for memory. The drug, memantine, is also often given with whole brain radiotherapy because it may decrease the risk of side effects related to thinking and memory. Stereotactic radiosurgery may decrease side effects related to memory and thinking compared to standard of care HA-WBRT plus memantine. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/14/2025
Locations: Mayo Clinic Hospital in Arizona, Phoenix, Arizona +213 locations
Mayo Clinic Hospital in Arizona, Phoenix, Arizona
Kaiser Permanente-Anaheim, Anaheim, California
Kaiser Permanente-Bellflower, Bellflower, California
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California
Los Angeles General Medical Center, Los Angeles, California
USC / Norris Comprehensive Cancer Center, Los Angeles, California
Kaiser Permanente-Ontario, Ontario, California
UCHealth University of Colorado Hospital, Aurora, Colorado
UCHealth Memorial Hospital Central, Colorado Springs, Colorado
Memorial Hospital North, Colorado Springs, Colorado
Smilow Cancer Hospital Care Center at Greenwich, Greenwich, Connecticut
Smilow Cancer Hospital Care Center - Guilford, Guilford, Connecticut
Smilow Cancer Center/Yale-New Haven Hospital, New Haven, Connecticut
Yale University, New Haven, Connecticut
Smilow Cancer Hospital Care Center-Trumbull, Trumbull, Connecticut
Smilow Cancer Hospital Care Center - Waterford, Waterford, Connecticut
Beebe Medical Center, Lewes, Delaware
Delaware Clinical and Laboratory Physicians PA, Newark, Delaware
Helen F Graham Cancer Center, Newark, Delaware
Medical Oncology Hematology Consultants PA, Newark, Delaware
Christiana Care Health System-Christiana Hospital, Newark, Delaware
Beebe Health Campus, Rehoboth Beach, Delaware
Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware
UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida
UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida
University of Florida Health Science Center - Gainesville, Gainesville, Florida
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida
Moffitt Cancer Center-International Plaza, Tampa, Florida
Moffitt Cancer Center - McKinley Campus, Tampa, Florida
Moffitt Cancer Center, Tampa, Florida
Moffitt Cancer Center at Wesley Chapel, Wesley Chapel, Florida
Emory University Hospital Midtown, Atlanta, Georgia
Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia
Emory Saint Joseph's Hospital, Atlanta, Georgia
Northside Hospital, Atlanta, Georgia
Northside Hospital-Cherokee, Canton, Georgia
Northside Hospital-Forsyth, Cumming, Georgia
Memorial Health University Medical Center, Savannah, Georgia
Rush - Copley Medical Center, Aurora, Illinois
Centralia Oncology Clinic, Centralia, Illinois
Rush University Medical Center, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Carle at The Riverfront, Danville, Illinois
Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois
Decatur Memorial Hospital, Decatur, Illinois
Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois
Carle Physician Group-Effingham, Effingham, Illinois
Crossroads Cancer Center, Effingham, Illinois
Northwestern Medicine Cancer Center Delnor, Geneva, Illinois
Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois
UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois
Cancer Care Center of O'Fallon, O'Fallon, Illinois
HSHS Saint Elizabeth's Hospital, O'Fallon, Illinois
OSF Saint Francis Medical Center, Peoria, Illinois
Carle Cancer Center, Urbana, Illinois
The Carle Foundation Hospital, Urbana, Illinois
Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois
IU Health West Hospital, Avon, Indiana
IU Health North Hospital, Carmel, Indiana
Goshen Center for Cancer Care, Goshen, Indiana
Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana
IU Health Methodist Hospital, Indianapolis, Indiana
Mary Greeley Medical Center, Ames, Iowa
McFarland Clinic - Ames, Ames, Iowa
Baptist Health Lexington, Lexington, Kentucky
The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky
UofL Health Medical Center Northeast, Louisville, Kentucky
Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana
Luminis Health Anne Arundel Medical Center, Annapolis, Maryland
University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland
MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore, Maryland
UM Upper Chesapeake Medical Center, Bel Air, Maryland
Central Maryland Radiation Oncology in Howard County, Columbia, Maryland
University of Maryland Shore Medical Center at Easton, Easton, Maryland
UM Baltimore Washington Medical Center/Tate Cancer Center, Glen Burnie, Maryland
TidalHealth Richard A Henson Cancer Institute, Ocean Pines, Maryland
TidalHealth Peninsula Regional, Salisbury, Maryland
Boston Medical Center, Boston, Massachusetts
Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan
Trinity Health Medical Center - Brighton, Brighton, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan
Trinity Health Medical Center - Canton, Canton, Michigan
Caro Cancer Center, Caro, Michigan
Chelsea Hospital, Chelsea, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan
Wayne State University/Karmanos Cancer Institute, Detroit, Michigan
Weisberg Cancer Treatment Center, Farmington Hills, Michigan
Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan
Saint Mary's Oncology/Hematology Associates of Marlette, Marlette, Michigan
MyMichigan Medical Center Saginaw, Saginaw, Michigan
Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan
MyMichigan Medical Center Tawas, Tawas City, Michigan
Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan
Sanford Joe Lueken Cancer Center, Bemidji, Minnesota
Minnesota Oncology - Burnsville, Burnsville, Minnesota
Mercy Hospital, Coon Rapids, Minnesota
Fairview Southdale Hospital, Edina, Minnesota
Unity Hospital, Fridley, Minnesota
Fairview Clinics and Surgery Center Maple Grove, Maple Grove, Minnesota
Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota
Abbott-Northwestern Hospital, Minneapolis, Minnesota
Monticello Cancer Center, Monticello, Minnesota
Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota
Regions Hospital, Saint Paul, Minnesota
United Hospital, Saint Paul, Minnesota
Lakeview Hospital, Stillwater, Minnesota
Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota
Saint Francis Medical Center, Cape Girardeau, Missouri
Parkland Health Center - Farmington, Farmington, Missouri
Freeman Health System, Joplin, Missouri
Missouri Baptist Medical Center, Saint Louis, Missouri
Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri
Mercy Hospital Springfield, Springfield, Missouri
Missouri Baptist Sullivan Hospital, Sullivan, Missouri
BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri
Billings Clinic Cancer Center, Billings, Montana
Benefis Sletten Cancer Institute, Great Falls, Montana
Logan Health Medical Center, Kalispell, Montana
Cooper Hospital University Medical Center, Camden, New Jersey
Montefiore Medical Center-Einstein Campus, Bronx, New York
Montefiore Medical Center-Weiler Hospital, Bronx, New York
Montefiore Medical Center - Moses Campus, Bronx, New York
Sands Cancer Center, Canandaigua, New York
Northwell Health/Center for Advanced Medicine, Lake Success, New York
Northern Westchester Hospital, Mount Kisco, New York
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York
Wilmot Cancer Institute Radiation Oncology at Greece, Rochester, New York
University of Rochester, Rochester, New York
State University of New York Upstate Medical University, Syracuse, New York
Upstate Cancer Center at Verona, Verona, New York
Wilmot Cancer Institute at Webster, Webster, New York
Wake Forest University Health Sciences, Winston-Salem, North Carolina
Sanford Bismarck Medical Center, Bismarck, North Dakota
Sanford Broadway Medical Center, Fargo, North Dakota
Sanford Roger Maris Cancer Center, Fargo, North Dakota
University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio
Case Western Reserve University, Cleveland, Ohio
Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Riverside Methodist Hospital, Columbus, Ohio
Grant Medical Center, Columbus, Ohio
Delaware Health Center-Grady Cancer Center, Delaware, Ohio
Grady Memorial Hospital, Delaware, Ohio
UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio
Mercy Health - Perrysburg Hospital, Perrysburg, Ohio
Mercy Health - Saint Anne Hospital, Toledo, Ohio
University of Cincinnati Cancer Center-West Chester, West Chester, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Saint Luke's Cancer Center - Allentown, Allentown, Pennsylvania
UPMC Altoona, Altoona, Pennsylvania
Saint Luke's University Hospital-Bethlehem Campus, Bethlehem, Pennsylvania
Carlisle Regional Cancer Center, Carlisle, Pennsylvania
Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania
Chambersburg Hospital, Chambersburg, Pennsylvania
Geisinger Medical Center, Danville, Pennsylvania
Saint Luke's Hospital-Anderson Campus, Easton, Pennsylvania
Ephrata Cancer Center, Ephrata, Pennsylvania
Saint Vincent Hospital, Erie, Pennsylvania
Adams Cancer Center, Gettysburg, Pennsylvania
UPMC Cancer Centers - Arnold Palmer Pavilion, Greensburg, Pennsylvania
UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg, Pennsylvania
Sechler Family Cancer Center, Lebanon, Pennsylvania
Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania
UPMC Cancer Center - Monroeville, Monroeville, Pennsylvania
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
Jefferson Torresdale Hospital, Philadelphia, Pennsylvania
Allegheny General Hospital, Pittsburgh, Pennsylvania
UPMC-Magee Womens Hospital, Pittsburgh, Pennsylvania
UPMC-Presbyterian Hospital, Pittsburgh, Pennsylvania
UPMC-Saint Margaret, Pittsburgh, Pennsylvania
UPMC-Shadyside Hospital, Pittsburgh, Pennsylvania
UPMC-Passavant Hospital, Pittsburgh, Pennsylvania
UPMC-Saint Clair Hospital Cancer Center, Pittsburgh, Pennsylvania
Saint Luke's Hospital - Upper Bucks Campus, Quakertown, Pennsylvania
Saint Luke's Hospital-Quakertown Campus, Quakertown, Pennsylvania
Saint Luke's Hospital - Monroe Campus, Stroudsburg, Pennsylvania
Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania
Divine Providence Hospital, Williamsport, Pennsylvania
WellSpan Health-York Cancer Center, York, Pennsylvania
WellSpan Health-York Hospital, York, Pennsylvania
UPMC Memorial, York, Pennsylvania
McLeod Regional Medical Center, Florence, South Carolina
Gibbs Cancer Center-Gaffney, Gaffney, South Carolina
Self Regional Healthcare, Greenwood, South Carolina
Gibbs Cancer Center-Pelham, Greer, South Carolina
Spartanburg Medical Center, Spartanburg, South Carolina
SMC Center for Hematology Oncology Union, Union, South Carolina
Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota
Avera Cancer Institute, Sioux Falls, South Dakota
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota
MD Anderson in The Woodlands, Conroe, Texas
M D Anderson Cancer Center, Houston, Texas
MD Anderson West Houston, Houston, Texas
MD Anderson League City, League City, Texas
MD Anderson in Sugar Land, Sugar Land, Texas
Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia
Langlade Hospital and Cancer Center, Antigo, Wisconsin
ThedaCare Regional Cancer Center, Appleton, Wisconsin
Gundersen Lutheran Medical Center, La Crosse, Wisconsin
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin
University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin
Froedtert Menomonee Falls Hospital, Menomonee Falls, Wisconsin
Medical College of Wisconsin, Milwaukee, Wisconsin
Cancer Center of Western Wisconsin, New Richmond, Wisconsin
Drexel Town Square Health Center, Oak Creek, Wisconsin
Aspirus Cancer Care - James Beck Cancer Center, Rhinelander, Wisconsin
Aspirus Cancer Care - Stevens Point, Stevens Point, Wisconsin
Aspirus Regional Cancer Center, Wausau, Wisconsin
Froedtert West Bend Hospital/Kraemer Cancer Center, West Bend, Wisconsin
University Health Network-Princess Margaret Hospital, Toronto, Ontario
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ), Quebec City, Quebec
Allan Blair Cancer Centre, Regina, Saskatchewan
Saskatoon Cancer Centre, Saskatoon, Saskatchewan
Conditions: Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Recurrent Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics
Recruiting
The purpose of the study is to evaluate effect of benralizumab on structural and lung function changes in severe eosinophilic asthmatics.
Changes will be assessed over 48 week treatment period in patients with persistent symptoms despite standard therapy of inhaled corticosteroids (ICS) plus long acting B2-agonist (LABA) with or without additional controller medication.
Patients who complete treatment will enter 4 weeks follow-up period.
The purpose of the study is to evaluate effect of benralizumab on structural and lung function changes in severe eosinophilic asthmatics.
Changes will be assessed over 48 week treatment period in patients with persistent symptoms despite standard therapy of inhaled corticosteroids (ICS) plus long acting B2-agonist (LABA) with or without additional controller medication.
Patients who complete treatment will enter 4 weeks follow-up period. Read Less
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/14/2025
Locations: Research Site, Birmingham, Alabama +52 locations
Research Site, Birmingham, Alabama
Research Site, Los Angeles, California
Research Site, Los Angeles, California
Research Site, Jacksonville, Florida
Research Site, Jacksonville, Florida
Research Site, Miami, Florida
Research Site, Decatur, Georgia
Research Site, Snellville, Georgia
Research Site, Indianapolis, Indiana
Research Site, Iowa City, Iowa
Research Site, Hutchinson, Kansas
Research Site, Kansas City, Kansas
Research Site, Baltimore, Maryland
Research Site, Boston, Massachusetts
Research Site, Ann Arbor, Michigan
Research Site, Bloomfield Hills, Michigan
Research Site, Rochester, Minnesota
Research Site, Saint Louis, Missouri
Research Site, Maspeth, New York
Research Site, Port Jefferson Station, New York
Research Site, Durham, North Carolina
Research Site, New Bern, North Carolina
Research Site, Winston-Salem, North Carolina
Research Site, Philadelphia, Pennsylvania
Research Site, Philadelphia, Pennsylvania
Research Site, Pittsburgh, Pennsylvania
Research Site, Sayre, Pennsylvania
Research Site, Charleston, South Carolina
Research Site, Galveston, Texas
Research Site, Lewisville, Texas
Research Site, Mansfield, Texas
Research Site, McAllen, Texas
Research Site, McKinney, Texas
Research Site, Williamsburg, Virginia
Research Site, Calgary, Alberta
Research Site, Edmonton, Alberta
Research Site, Hamilton, Ontario
Research Site, Aarhus N, Not set
Research Site, Hvidovre, Not set
Research Site, København, Not set
Research Site, Naestved, Not set
Research Site, Odense C, Not set
Research Site, Vejle, Not set
Research Site, Ålborg, Not set
Research Site, Göteborg, Not set
Research Site, Lund, Not set
Research Site, Cambridge, Not set
Research Site, Headington, Not set
Research Site, Leicester, Not set
Research Site, Liverpool, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, Wythenshawe, Not set
Conditions: Asthma
A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia
Recruiting
The purpose of this study is to evaluate the safety, tolerability and determine the recommended dose for further clinical evaluation of ELVN-001 in patients with chronic myeloid leukemia with and without T315I mutations in patients who are relapsed, refractory or intolerant to TKIs.
The purpose of this study is to evaluate the safety, tolerability and determine the recommended dose for further clinical evaluation of ELVN-001 in patients with chronic myeloid leukemia with and without T315I mutations in patients who are relapsed, refractory or intolerant to TKIs. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/14/2025
Locations: Montefiore Medical Center, Bronx, New York +43 locations
Montefiore Medical Center, Bronx, New York
Memorial Sloan Kettering Cancer Center, New York, New York
Oregon Health & Science University-Knight Cardiovascular Institute, Portland, Oregon
The University of Texas MD Anderson Cancer Center, Houston, Texas
Royal Adelaide Hospital, Adelaide, Not set
UZ Gent, Gent, Not set
CHU Liege, Liège, Not set
University Health Network (UHN) - Princess Margaret Cancer Centre, Toronto, Ontario
CHU Amiens Picardie Site Sud, Amiens, Not set
Institut Bergonie - Centre Regional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest, Bordeaux, Not set
Centre Hospitalier de Versailles (CHV), Le Chesnay, Not set
CHRU de Lille - Hopital Calmette-Boulevard du Pr Leclercq CHRU Lille, Lille, Not set
Centre Hospitalier Universitaire (CHU) De Limoges Hopital Dupuytren, Limoges, Not set
Centre Leon Berard, Lyon, Not set
Centre Hospitalier Lyon Sud, Pierre Benite Cedex, Not set
Uniklinik RWTH Aachen Medizinische, Aachen, Not set
Charite Campus Virchow, Berlin, Not set
Klinikum der Goethe Universitat, Frankfurt, Not set
Universitaetsklinikum Des Saarlandes Und Medizinische Fakultaet Der Universitaet Des Saarlandes, Homburg, Not set
Universitaetsklinikum Jena, Jena, Not set
Medizinische Universitatsklinik Mannheim der Universitat Heidelberg, Mannheim, Not set
Universitaetsmedizin Rostock, Rostock, Not set
Semmelweis Egyetem, Belgyogyaszati es Onkologiai Klinika, Budapest, Not set
Pecsi Tudomanyegyetem Klinikai Kozpont (University of Pecs, Clinical Centre), Pécs, Not set
Hadassah Medical Center, Jerusalem, Not set
The Galilee Medical Center, Nahariya, Not set
Rabin Medical Center, Petah Tikva, Not set
Azienda Ospedaliero Universitaria Delle Marche, Ancona, Not set
Chonbuk National University Hospital, Jeonju, Jeollabuk-do
Keimyung University Dongsan Hospital, Daegu, Not set
Uijeongbu Eulji Medical Center, Gyeonggi-do, Not set
Chonnam National University Hwasun Hospital, Hwasun, Not set
Samsung Medical Center, Seoul, Not set
Radboud University Medical Center, Nijmegen, Not set
Szpital Specjalistycnzy im. Jedrzeja Sniadeckiego w Nowym Saczu, Nowy Sącz, Not set
MICS Centrum Medyczne Torun, Toruń, Not set
Hospital Del Mar, Barcelona, Not set
Hospital Universitario de Gran Canaria Dr. Negrin, Servicio Canario e Salud (SCS), Las Palmas De Gran Canaria, Not set
Hospital Universitario La Paz, Madrid, Not set
Complejo Hospitalario de Toledo - Hospital Virgen de la Salud, Toledo, Not set
Universitat de Valencia - Hospital Universitari i Politecnic La Fe de Valencia (Hospital La Fe Bulevar Sur), Valencia, Not set
Beatson West of Scotland Cancer Centre, Gartnavel General Hospital, Glasgow, Not set
Hammersmith Hospital Imperial College Healthcare NHS Trust, London, Not set
The Christie NHS Foundation Trust, Manchester, Not set
Conditions: Chronic Myeloid Leukemia, Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive, Cml
Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma
Recruiting
This phase III trial compares the effect of adding lomustine to standard chemotherapy with temozolomide and radiation therapy versus temozolomide and radiation therapy alone in shrinking or stabilizing newly diagnosed MGMT methylated glioblastoma. MGMT methylated tumors are more likely to respond to temozolomide chemotherapy. Temozolomide is in a class of medications called alkylating agents. It works by damaging the cell's DNA and may kill tumor cells and slow down or stop tumor growth. Lomusti... Read More
This phase III trial compares the effect of adding lomustine to standard chemotherapy with temozolomide and radiation therapy versus temozolomide and radiation therapy alone in shrinking or stabilizing newly diagnosed MGMT methylated glioblastoma. MGMT methylated tumors are more likely to respond to temozolomide chemotherapy. Temozolomide is in a class of medications called alkylating agents. It works by damaging the cell's DNA and may kill tumor cells and slow down or stop tumor growth. Lomustine is a chemotherapy drug and in a class of medications called alkylating agents. It damages the cell's DNA and may kill tumor cells. Radiation therapy uses high energy x-ray photons to kill tumor cells and shrink tumors. Adding lomustine to standard chemotherapy with temozolomide and radiation therapy may shrink or stabilize glioblastoma. Read Less
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/14/2025
Locations: Fairbanks Memorial Hospital, Fairbanks, Alaska +398 locations
Fairbanks Memorial Hospital, Fairbanks, Alaska
Highlands Oncology Group - Fayetteville, Fayetteville, Arkansas
University of Arkansas for Medical Sciences, Little Rock, Arkansas
Highlands Oncology Group - Rogers, Rogers, Arkansas
Highlands Oncology Group, Springdale, Arkansas
Kaiser Permanente-Anaheim, Anaheim, California
Kaiser Permanente-Deer Valley Medical Center, Antioch, California
Sutter Auburn Faith Hospital, Auburn, California
Sutter Cancer Centers Radiation Oncology Services-Auburn, Auburn, California
Kaiser Permanente-Bellflower, Bellflower, California
Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California
Mercy Cancer Center - Carmichael, Carmichael, California
Mercy San Juan Medical Center, Carmichael, California
John Muir Medical Center-Concord, Concord, California
City of Hope Comprehensive Cancer Center, Duarte, California
Kaiser Permanente Dublin, Dublin, California
Mercy Cancer Center - Elk Grove, Elk Grove, California
Kaiser Permanente-Fremont, Fremont, California
Palo Alto Medical Foundation-Fremont, Fremont, California
Fresno Cancer Center, Fresno, California
Kaiser Permanente-Fresno, Fresno, California
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine, California
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California
Kaiser Permanente-Modesto, Modesto, California
Palo Alto Medical Foundation-Camino Division, Mountain View, California
Kaiser Permanente Oakland-Broadway, Oakland, California
Kaiser Permanente-Oakland, Oakland, California
Kaiser Permanente-Ontario, Ontario, California
UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California
Palo Alto Medical Foundation Health Care, Palo Alto, California
Kaiser Permanente-Rancho Cordova Cancer Center, Rancho Cordova, California
Kaiser Permanente- Marshall Medical Offices, Redwood City, California
Kaiser Permanente-Richmond, Richmond, California
Mercy Cancer Center - Rocklin, Rocklin, California
Rohnert Park Cancer Center, Rohnert Park, California
Kaiser Permanente-Roseville, Roseville, California
Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California
Sutter Roseville Medical Center, Roseville, California
The Permanente Medical Group-Roseville Radiation Oncology, Roseville, California
Kaiser Permanente Downtown Commons, Sacramento, California
Mercy Cancer Center - Sacramento, Sacramento, California
Sutter Medical Center Sacramento, Sacramento, California
Kaiser Permanente-South Sacramento, Sacramento, California
South Sacramento Cancer Center, Sacramento, California
Kaiser Permanente-San Diego Zion, San Diego, California
California Pacific Medical Center-Pacific Campus, San Francisco, California
Kaiser Permanente-San Francisco, San Francisco, California
Kaiser Permanente-Santa Teresa-San Jose, San Jose, California
Kaiser Permanente San Leandro, San Leandro, California
Kaiser San Rafael-Gallinas, San Rafael, California
Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California
Kaiser Permanente-Santa Rosa, Santa Rosa, California
Sutter Pacific Medical Foundation, Santa Rosa, California
Kaiser Permanente Cancer Treatment Center, South San Francisco, California
Kaiser Permanente-South San Francisco, South San Francisco, California
Kaiser Permanente-Stockton, Stockton, California
Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California
Kaiser Permanente Medical Center-Vacaville, Vacaville, California
Kaiser Permanente-Vallejo, Vallejo, California
Kaiser Permanente-Walnut Creek, Walnut Creek, California
John Muir Medical Center-Walnut Creek, Walnut Creek, California
Woodland Memorial Hospital, Woodland, California
Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado
UCHealth Memorial Hospital Central, Colorado Springs, Colorado
Memorial Hospital North, Colorado Springs, Colorado
Poudre Valley Hospital, Fort Collins, Colorado
Cancer Care and Hematology-Fort Collins, Fort Collins, Colorado
Lutheran Hospital - Cancer Centers of Colorado, Golden, Colorado
UCHealth Greeley Hospital, Greeley, Colorado
AdventHealth Littleton, Littleton, Colorado
Medical Center of the Rockies, Loveland, Colorado
AdventHealth Parker, Parker, Colorado
Baptist MD Anderson Cancer Center, Jacksonville, Florida
Miami Cancer Institute, Miami, Florida
Emory University Hospital Midtown, Atlanta, Georgia
Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia
Augusta University Medical Center, Augusta, Georgia
Memorial Health University Medical Center, Savannah, Georgia
Saint Luke's Cancer Institute - Boise, Boise, Idaho
Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho
Saint Luke's Cancer Institute - Meridian, Meridian, Idaho
Saint Luke's Cancer Institute - Nampa, Nampa, Idaho
Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho
Alton Memorial Hospital, Alton, Illinois
Rush - Copley Medical Center, Aurora, Illinois
Advocate Outpatient Center - Aurora, Aurora, Illinois
Advocate Good Shepherd Hospital, Barrington, Illinois
Illinois CancerCare-Bloomington, Bloomington, Illinois
Illinois CancerCare-Canton, Canton, Illinois
Illinois CancerCare-Carthage, Carthage, Illinois
Centralia Oncology Clinic, Centralia, Illinois
University of Illinois, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Advocate Illinois Masonic Medical Center, Chicago, Illinois
AMG Crystal Lake - Oncology, Crystal Lake, Illinois
Carle at The Riverfront, Danville, Illinois
Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois
Decatur Memorial Hospital, Decatur, Illinois
Advocate Good Samaritan Hospital, Downers Grove, Illinois
Carle Physician Group-Effingham, Effingham, Illinois
Crossroads Cancer Center, Effingham, Illinois
Advocate Sherman Hospital, Elgin, Illinois
Illinois CancerCare-Eureka, Eureka, Illinois
Illinois CancerCare-Galesburg, Galesburg, Illinois
Advocate South Suburban Hospital, Hazel Crest, Illinois
Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois
AMG Libertyville - Oncology, Libertyville, Illinois
Illinois CancerCare-Macomb, Macomb, Illinois
Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois
UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois
Cancer Care Center of O'Fallon, O'Fallon, Illinois
HSHS Saint Elizabeth's Hospital, O'Fallon, Illinois
Advocate Christ Medical Center, Oak Lawn, Illinois
University of Chicago Medicine-Orland Park, Orland Park, Illinois
Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois
Advocate Lutheran General Hospital, Park Ridge, Illinois
Illinois CancerCare-Pekin, Pekin, Illinois
Illinois CancerCare-Peoria, Peoria, Illinois
OSF Saint Francis Medical Center, Peoria, Illinois
Illinois CancerCare-Peru, Peru, Illinois
Illinois CancerCare-Princeton, Princeton, Illinois
Memorial Hospital East, Shiloh, Illinois
Southern Illinois University School of Medicine, Springfield, Illinois
Springfield Clinic, Springfield, Illinois
Springfield Memorial Hospital, Springfield, Illinois
Carle Cancer Center, Urbana, Illinois
The Carle Foundation Hospital, Urbana, Illinois
Illinois CancerCare - Washington, Washington, Illinois
Northwest Cancer Center - Main Campus, Crown Point, Indiana
UChicago Medicine Northwest Indiana, Crown Point, Indiana
Northwest Oncology LLC, Dyer, Indiana
Northwest Cancer Center - Hobart, Hobart, Indiana
Saint Mary Medical Center, Hobart, Indiana
Community Cancer Center East, Indianapolis, Indiana
Community Cancer Center South, Indianapolis, Indiana
Community Cancer Center North, Indianapolis, Indiana
The Community Hospital, Munster, Indiana
Women's Diagnostic Center - Munster, Munster, Indiana
Northwest Cancer Center - Valparaiso, Valparaiso, Indiana
Mary Greeley Medical Center, Ames, Iowa
McFarland Clinic - Ames, Ames, Iowa
UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa
Mercy Hospital, Cedar Rapids, Iowa
Oncology Associates at Mercy Medical Center, Cedar Rapids, Iowa
Mercy Cancer Center-West Lakes, Clive, Iowa
UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive, Iowa
Greater Regional Medical Center, Creston, Iowa
UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa
Broadlawns Medical Center, Des Moines, Iowa
Mercy Medical Center - Des Moines, Des Moines, Iowa
UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa
Siouxland Regional Cancer Center, Sioux City, Iowa
UI Health Care Mission Cancer and Blood - Waukee Clinic, Waukee, Iowa
Mercy Medical Center-West Lakes, West Des Moines, Iowa
University of Kansas Cancer Center, Kansas City, Kansas
University of Kansas Cancer Center-Overland Park, Overland Park, Kansas
University of Kansas Hospital-Indian Creek Campus, Overland Park, Kansas
University of Kansas Hospital-Westwood Cancer Center, Westwood, Kansas
Ascension Via Christi Hospitals Wichita, Wichita, Kansas
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky
Norton Brownsboro Hospital and Medical Campus, Louisville, Kentucky
UofL Health Medical Center Northeast, Louisville, Kentucky
Lafayette Family Cancer Center-EMMC, Brewer, Maine
University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland
Central Maryland Radiation Oncology in Howard County, Columbia, Maryland
UM Baltimore Washington Medical Center/Tate Cancer Center, Glen Burnie, Maryland
Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan
Trinity Health Medical Center - Brighton, Brighton, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan
Trinity Health Medical Center - Canton, Canton, Michigan
Caro Cancer Center, Caro, Michigan
Chelsea Hospital, Chelsea, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan
Henry Ford Health Saint John Hospital, Detroit, Michigan
Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids, Michigan
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan
Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan
Henry Ford Saint John Hospital - Van Elslander, Grosse Pointe Woods, Michigan
Bronson Methodist Hospital, Kalamazoo, Michigan
West Michigan Cancer Center, Kalamazoo, Michigan
Ascension Borgess Hospital, Kalamazoo, Michigan
University of Michigan Health - Sparrow Lansing, Lansing, Michigan
Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan
Henry Ford Saint John Hospital - Macomb Medical, Macomb, Michigan
Saint Mary's Oncology/Hematology Associates of Marlette, Marlette, Michigan
Michigan Healthcare Professionals Pontiac, Pontiac, Michigan
Trinity Health Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan
MyMichigan Medical Center Saginaw, Saginaw, Michigan
Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan
MyMichigan Medical Center Tawas, Tawas City, Michigan
Henry Ford Health Warren Hospital, Warren, Michigan
Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan
University of Michigan Health - West, Wyoming, Michigan
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan
Sanford Joe Lueken Cancer Center, Bemidji, Minnesota
Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota
Fairview Ridges Hospital, Burnsville, Minnesota
Minnesota Oncology - Burnsville, Burnsville, Minnesota
Mercy Hospital, Coon Rapids, Minnesota
Essentia Health - Deer River Clinic, Deer River, Minnesota
Essentia Health Cancer Center, Duluth, Minnesota
Essentia Health Saint Mary's Medical Center, Duluth, Minnesota
Miller-Dwan Hospital, Duluth, Minnesota
Fairview Southdale Hospital, Edina, Minnesota
Unity Hospital, Fridley, Minnesota
Essentia Health Hibbing Clinic, Hibbing, Minnesota
Fairview Clinics and Surgery Center Maple Grove, Maple Grove, Minnesota
Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota
Saint John's Hospital - Healtheast, Maplewood, Minnesota
Abbott-Northwestern Hospital, Minneapolis, Minnesota
Hennepin County Medical Center, Minneapolis, Minnesota
Health Partners Inc, Minneapolis, Minnesota
Monticello Cancer Center, Monticello, Minnesota
North Memorial Medical Health Center, Robbinsdale, Minnesota
Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota
Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota
Regions Hospital, Saint Paul, Minnesota
United Hospital, Saint Paul, Minnesota
Essentia Health Sandstone, Sandstone, Minnesota
Lakeview Hospital, Stillwater, Minnesota
Essentia Health Virginia Clinic, Virginia, Minnesota
Ridgeview Medical Center, Waconia, Minnesota
Saint Francis Medical Center, Cape Girardeau, Missouri
Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri
Parkland Health Center - Farmington, Farmington, Missouri
Research Medical Center, Kansas City, Missouri
University of Kansas Cancer Center - North, Kansas City, Missouri
University of Kansas Cancer Center - Lee's Summit, Lee's Summit, Missouri
University of Kansas Cancer Center at North Kansas City Hospital, North Kansas City, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Siteman Cancer Center-South County, Saint Louis, Missouri
Missouri Baptist Medical Center, Saint Louis, Missouri
Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri
Mercy Hospital Saint Louis, Saint Louis, Missouri
Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri
Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri
Mercy Hospital Springfield, Springfield, Missouri
Missouri Baptist Sullivan Hospital, Sullivan, Missouri
BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri
Billings Clinic Cancer Center, Billings, Montana
Bozeman Health Deaconess Hospital, Bozeman, Montana
Renown Regional Medical Center, Reno, Nevada
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire
Englewood Hospital and Medical Center, Englewood, New Jersey
Jersey City Medical Center, Jersey City, New Jersey
Saint Barnabas Medical Center, Livingston, New Jersey
Monmouth Medical Center, Long Branch, New Jersey
Jersey Shore Medical Center, Neptune, New Jersey
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Rutgers New Jersey Medical School, Newark, New Jersey
Community Medical Center, Toms River, New Jersey
University of New Mexico Cancer Center, Albuquerque, New Mexico
Sands Cancer Center, Canandaigua, New York
Noyes Memorial Hospital/Myers Cancer Center, Dansville, New York
Northwell Health/Center for Advanced Medicine, Lake Success, New York
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York
University of Rochester, Rochester, New York
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Sanford Bismarck Medical Center, Bismarck, North Dakota
Sanford Broadway Medical Center, Fargo, North Dakota
Sanford Roger Maris Cancer Center, Fargo, North Dakota
Cleveland Clinic Akron General, Akron, Ohio
Indu and Raj Soin Medical Center, Beavercreek, Ohio
Dayton Physicians LLC-Miami Valley South, Centerville, Ohio
Miami Valley Hospital South, Centerville, Ohio
Adena Regional Medical Center, Chillicothe, Ohio
University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio
Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio
MetroHealth Medical Center, Cleveland, Ohio
Cleveland Clinic Foundation, Cleveland, Ohio
Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Riverside Methodist Hospital, Columbus, Ohio
Miami Valley Hospital, Dayton, Ohio
Premier Blood and Cancer Center, Dayton, Ohio
Dayton Physician LLC - Englewood, Dayton, Ohio
Miami Valley Hospital North, Dayton, Ohio
Dublin Methodist Hospital, Dublin, Ohio
Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio
Dayton Physicians LLC-Atrium, Franklin, Ohio
Dayton Physicians LLC-Wayne, Greenville, Ohio
Miami Valley Cancer Care and Infusion, Greenville, Ohio
Wayne Hospital, Greenville, Ohio
Kettering Medical Center, Kettering, Ohio
ProMedica Flower Hospital, Sylvania, Ohio
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio
Dayton Physicians LLC - Troy, Troy, Ohio
Upper Valley Medical Center, Troy, Ohio
University of Cincinnati Cancer Center-West Chester, West Chester, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma
Legacy Mount Hood Medical Center, Gresham, Oregon
Providence Newberg Medical Center, Newberg, Oregon
Legacy Good Samaritan Hospital and Medical Center, Portland, Oregon
Providence Saint Vincent Medical Center, Portland, Oregon
Kaiser Permanente Northwest, Portland, Oregon
Legacy Meridian Park Hospital, Tualatin, Oregon
Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania
UPMC Altoona, Altoona, Pennsylvania
Geisinger Medical Center, Danville, Pennsylvania
UPMC Hillman Cancer Center Erie, Erie, Pennsylvania
UPMC Cancer Center at UPMC Horizon, Farrell, Pennsylvania
UPMC Cancer Centers - Arnold Palmer Pavilion, Greensburg, Pennsylvania
Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania
Jefferson Hospital, Jefferson Hills, Pennsylvania
UPMC-Johnstown/John P. Murtha Regional Cancer Center, Johnstown, Pennsylvania
Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania
Forbes Hospital, Monroeville, Pennsylvania
Allegheny General Hospital, Pittsburgh, Pennsylvania
University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania
UPMC-Shadyside Hospital, Pittsburgh, Pennsylvania
UPMC-Passavant Hospital, Pittsburgh, Pennsylvania
Geisinger Cancer Services-Pottsville, Pottsville, Pennsylvania
Reading Hospital, West Reading, Pennsylvania
Wexford Health and Wellness Pavilion, Wexford, Pennsylvania
Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania
Roper Hospital, Charleston, South Carolina
Charleston Oncology - Roper, Charleston, South Carolina
Bon Secours Saint Francis Hospital, Charleston, South Carolina
Charleston Oncology - Saint Francis, Charleston, South Carolina
Avera Cancer Institute at Pierre, Pierre, South Dakota
Rapid City Regional Hospital, Rapid City, South Dakota
Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota
Avera Cancer Institute, Sioux Falls, South Dakota
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota
Avera Cancer Institute at Yankton, Yankton, South Dakota
Parkland Memorial Hospital, Dallas, Texas
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas
Ben Taub General Hospital, Houston, Texas
Memorial Hermann Texas Medical Center, Houston, Texas
American Fork Hospital / Huntsman Intermountain Cancer Center, American Fork, Utah
Sandra L Maxwell Cancer Center, Cedar City, Utah
Logan Regional Hospital, Logan, Utah
Intermountain Medical Center, Murray, Utah
McKay-Dee Hospital Center, Ogden, Utah
Utah Valley Regional Medical Center, Provo, Utah
Riverton Hospital, Riverton, Utah
Saint George Regional Medical Center, Saint George, Utah
Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah
LDS Hospital, Salt Lake City, Utah
Central Vermont Medical Center/National Life Cancer Treatment, Berlin, Vermont
University of Vermont Medical Center, Burlington, Vermont
University of Vermont and State Agricultural College, Burlington, Vermont
Dartmouth Cancer Center - North, Saint Johnsbury, Vermont
Inova Alexandria Hospital, Alexandria, Virginia
Inova Schar Cancer Institute, Fairfax, Virginia
Inova Fair Oaks Hospital, Fairfax, Virginia
Bon Secours Memorial Regional Medical Center, Mechanicsville, Virginia
Bon Secours Saint Francis Medical Center, Midlothian, Virginia
Bon Secours Saint Mary's Hospital, Richmond, Virginia
Henrico Doctor's Hospital, Richmond, Virginia
Bon Secours Cancer Institute at Reynolds Crossing, Richmond, Virginia
VCU Massey Cancer Center at Stony Point, Richmond, Virginia
Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia
Virginia Mason Medical Center, Seattle, Washington
Legacy Cancer Institute Medical Oncology and Day Treatment, Vancouver, Washington
Legacy Salmon Creek Hospital, Vancouver, Washington
West Virginia University Healthcare, Morgantown, West Virginia
Langlade Hospital and Cancer Center, Antigo, Wisconsin
Duluth Clinic Ashland, Ashland, Wisconsin
Northwest Wisconsin Cancer Center, Ashland, Wisconsin
Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin
Aurora Health Care Germantown Health Center, Germantown, Wisconsin
Aurora Cancer Care-Grafton, Grafton, Wisconsin
Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin
Aurora BayCare Medical Center, Green Bay, Wisconsin
Essentia Health-Hayward Clinic, Hayward, Wisconsin
University of Wisconsin Carbone Cancer Center - Johnson Creek, Johnson Creek, Wisconsin
Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin
Gundersen Lutheran Medical Center, La Crosse, Wisconsin
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin
University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin
Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin
Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin
Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin
Aurora Sinai Medical Center, Milwaukee, Wisconsin
ProHealth D N Greenwald Center, Mukwonago, Wisconsin
Cancer Center of Western Wisconsin, New Richmond, Wisconsin
ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin
Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin
Aurora Cancer Care-Racine, Racine, Wisconsin
Aspirus Cancer Care - James Beck Cancer Center, Rhinelander, Wisconsin
Saint Vincent Hospital Cancer Center at Sheboygan, Sheboygan, Wisconsin
Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin
Essentia Health-Spooner Clinic, Spooner, Wisconsin
Aspirus Cancer Care - Stevens Point, Stevens Point, Wisconsin
Saint Vincent Hospital Cancer Center at Sturgeon Bay, Sturgeon Bay, Wisconsin
Aurora Medical Center in Summit, Summit, Wisconsin
Essentia Health Saint Mary's Hospital - Superior, Superior, Wisconsin
Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin
UW Cancer Center at ProHealth Care, Waukesha, Wisconsin
Aspirus Regional Cancer Center, Wausau, Wisconsin
Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin
Aurora West Allis Medical Center, West Allis, Wisconsin
Aspirus Cancer Care - Wisconsin Rapids, Wisconsin Rapids, Wisconsin
CHUM - Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec
The Research Institute of the McGill University Health Centre (MUHC), Montreal, Quebec
Conditions: Glioblastoma, Gliosarcoma
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