The state of California currently has 157 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Los Angeles, San Francisco, San Diego and Sacramento.
EPPIC-Net: Platform Protocol to Assess Treatments for Painful Diabetic Peripheral Neuropathy
NCT05476276
Recruiting
This is a Platform Protocol to perform Phase II clinical trials in The Early Phase Pain Investigation Clinical Network (EPPIC-Net), under The Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, related to the treatment of Painful Diabetic Peripheral Neuropathy (PDPN) in a platform setting to test multiple assets under a single protocol.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: University of California, San Diego, San Diego, California
Conditions: Painful Diabetic Neuropathy
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EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISA
NCT05480228
Recruiting
The purpose of this study is to investigate the safety and efficacy of the current hard gelatin capsule formulation of NRD135S.E1 80 mg once daily in the treatment of PDPN when administered for 13 weeks.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: University of California, San Diego, San Diego, California
Conditions: Painful Diabetic Neuropathy
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Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS
NCT05737121
Recruiting
This is a Phase 2, prospective, randomized, double-blind, placebo-controlled, multi-center, single-dose, pharmacodynamic study designed to evaluate the efficacy and safety of the combination product (VNX001) versus placebo and its individual components (heparin sodium and lidocaine hydrochloride (HCl)) for the reduction of bladder pain in patients with interstitial cystitis (IC) / bladder pain syndrome (BPS).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: IC Study LLC, Escondido, California +4 locations
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
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RELIEF - A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
NCT01719055
Recruiting
To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use - and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice
Gender:
All
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: Comprehensive Pain Management Center, Campbell, California +5 locations
Conditions: Pain
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Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain
NCT06361485
Recruiting
This is a Pilot Study that is an open label, prospective, non-controlled study in which the safety and feasibility of Wharton's Jelly (WJ) allograft will be evaluated in 100 participants suffering with low back pain.
Gender:
All
Ages:
20 years and above
Trial Updated:
04/09/2024
Locations: R3 Anti Aging Beverly Hills, Beverly Hills, California
Conditions: Low Back Pain
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Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain
NCT05285007
Recruiting
The purpose of this graduate student research study is to investigate the relationship between limited ankle dorsiflexion and the potential effects on a single limb squat task in the Patellofemoral/Knee Pain population.
Gender:
Female
Ages:
Between 18 years and 59 years
Trial Updated:
04/08/2024
Locations: Loma Linda University, Loma Linda, California
Conditions: Patellofemoral Pain
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Patient Retrospective Outcomes (PRO)
NCT01550575
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/05/2024
Locations: Kern Neuroscience Institute, Bakersfield, California +8 locations
Conditions: Chronic Pain
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A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain
NCT05359133
Recruiting
To be eligible for the trial, subjects must have ongoing moderate to severe neuropathic pain related to a prior course of platinum and/or taxane chemotherapy and have no clinical evidence of actively progressive disease. The trial period will comprise a Screening period (up to 35 Days), randomization and a 4-day treatment period, followed by a 12-week follow up period (12 weeks total after initial treatment), and an End-of-Trial/Follow-up visit which will occur at Week 13. This is a study to re... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
04/05/2024
Locations: Syrentis Clinical Research, Santa Ana, California +1 locations
Conditions: Chemotherapy-induced Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
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A DirEct to PatieNt Study in Chronic Pain
NCT05515341
Recruiting
To compile real-world, direct from patient clinical outcomes and objective metrics in patients who have received or plan to receive a commercially approved interventional medical device therapy/procedure for chronic pain in routine clinical practice.
Gender:
All
Ages:
22 years and above
Trial Updated:
04/05/2024
Locations: Boston Scientific Neuromodulation, Valencia, California
Conditions: Chronic Pain
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Single-Session "Empowered Relief" Class for Marfan Syndrome and Related Conditions
NCT05980104
Recruiting
Empowered Relief (ER) is a 1-session pain relief skills intervention that is delivered in-person or online by certified clinicians to groups of patients with acute or chronic pain. Prior work in has shown ER efficacy for reducing chronic pain, pain-related distress, and other symptoms 6 months post-treatment. The purpose of this study is to conduct the first feasibility and early efficacy test of online ER (two hours total treatment time) delivered to individuals with Marfan syndrome, Vascular E... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/05/2024
Locations: Stanford University, Palo Alto, California
Conditions: Chronic Pain, Marfan Syndrome, Vascular Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome
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A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)
NCT06203002
Recruiting
Evaluation of the efficacy of LX9211 compared to placebo in reducing DPNP.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/04/2024
Locations: Lexicon Investigational Site (107), Anaheim, California +6 locations
Conditions: Diabetic Peripheral Neuropathic Pain
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Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.
NCT04860141
Recruiting
This study is a double-blind, randomized, prospective, placebo-controlled single-center clinical research study in which 600 mg of gabapentin or placebo will be administered 2 hours preoperatively to 49 patients each undergoing wisdom teeth extraction. We will measure intraoperative opioid use, severity of pain, the number of analgesics taken, and side effect profiles (e.g. nausea/vomiting, dizziness) at the following intervals, 4 hour, 8 hour, 12 hour, 24, and 72 hour post-procedure.
Gender:
All
Ages:
Between 18 years and 59 years
Trial Updated:
04/03/2024
Locations: Loma Linda University Health, Loma Linda, California
Conditions: Dental Pain and Sensation Disorder, Pain, Postoperative
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