There are currently 1908 clinical trials in Los Angeles, California looking for participants to engage in research studies. Trials are conducted at various facilities, including Cedars-Sinai Medical Center, USC Norris Comprehensive Cancer Center, Children's Hospital Los Angeles and University of California Los Angeles. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Contrast EUS of the Pancreas
NCT02863770
Recruiting
RATIONALE: Endoscopic Ultrasound (EUS) is the leading method to evaluate the pancreas but there may be difficulty characterizing small lesions, tumors which are not adenocarcinomas and neoplasia in the setting of pancreatitis. INTERVENTION: The innovation in this project will be the addition of intravenous contrast to standard EUS examination if the pancreas. PURPOSE: The aim is to determine if contrast enhances the ability of EUS to accurately diagnose lesions and target biopsies, and to defi... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
03/02/2023
Locations: Los Angeles County Hospital, Los Angeles, California
Conditions: Pancreatic Neoplasms, Pancreatitis, Pancreatic Cyst
Register for Updates
Impact of AI on Trainee ADR
NCT05423964
Recruiting
Adenoma detection rate (ADR) is a validated quality metric for colonoscopy with higher ADR correlated with improved colorectal cancer outcomes. Artificial intelligence (AI) can automatically detect polyps on the video monitor which may allow endoscopists in training to improve their ADR. Objective and Purpose of the study: Measure the effect of AI in a prospective, randomized manner to determine its impact on ADR of Gastroenterology trainees.
Gender:
All
Ages:
All
Trial Updated:
03/02/2023
Locations: LAC+USC Medical Center, Los Angeles, California
Conditions: Adenoma, Adenoma Colon, Colorectal Cancer
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Antibiotics to Decrease Post ERCP Cholangitis
NCT03087656
Recruiting
Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic procedure used to treat bile duct stones, obstructive jaundice, biliary leaks, and a variety of other conditions. There is active debate whether antibiotics should be given prophylactically for ERCP outside of high risk indications including primary sclerosing cholangitis. In part this is due to a lack of appropriately powered clinical trials with adequate follow up. The aim will be to assess whether prophylactic antibiotics... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
03/02/2023
Locations: Los Angeles County Hospital, Los Angeles, California
Conditions: Cholangitis
Register for Updates
Regular vs. Clear Liquid Diet for Mild to Moderate Acute Pancreatitis
NCT04932785
Recruiting
Acute pancreatitis is among the most common gastroenterology diagnosis in the United States, and represents a large economic burden to the United States health system. While recent guidelines agree early feeding shortens length of stay, these guidelines fail to provide recommendations on optimal diet to start leaving diet type to clinician discretion. Therefore, the aim is to assess the comparative efficacy of full calorie regular diet (RD) versus clear liquid diet (CLD) on length of hospital st... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/02/2023
Locations: LAC+USC Medical Center, Los Angeles, California
Conditions: Pancreatitis, Diet, Food, and Nutrition, Diet, Pancreatic Disease, Enteral Nutrition
Register for Updates
A CHW Intervention to Identify and Decrease Barriers to COVID 19 Testing & Vaccination
NCT05473936
Recruiting
The objective of this study is to compare the results of a COVID-19 specific curriculum led by LACDHS Community Health Workers (CHWs) from these same communities of safety-net patients to effectively increase COVID-19 testing and vaccination for individual patients, and to facilitate needed healthcare in a timely manner for the safety net health system, and to develop a sustained public health presence in these communities to build trust and preparedness for critical COVID-19 related future need... Read More
Gender:
All
Ages:
16 years and above
Trial Updated:
02/28/2023
Locations: Los Angeles Department of Public Health, Los Angeles, California +1 locations
Conditions: Vaccine Hesitancy, COVID-19 Testing, Community Health Workers
Register for Updates
EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study
NCT05610787
Recruiting
The purpose of this study is to evaluate the device performance and monitor the safety and effectiveness of the Berlin Heart EXCOR Active Driving System while being used with the approved EXCOR Pediatric Ventricular Assist Device. EXCOR Active Driving System is intended for use with the approved EXCOR Pediatric VAD. The EXCOR Pediatric VAD is intended to provide mechanical circulatory support as a bridge to cardiac transplantation for pediatric patients. Pediatric candidates with severe isolat... Read More
Gender:
All
Ages:
21 years and below
Trial Updated:
02/06/2023
Locations: Children's Hospital of Los Angeles, Los Angeles, California
Conditions: Heart Failure, Transplant; Failure, Heart, Congenital Heart Disease
Register for Updates
Whole-Heart Myocardial Blood Flow Quantification Using MRI
NCT03064295
Recruiting
This study hopes to provide significant technical improvement in a Myocardial Blood Flow (MBF) cardiac magnetic resonance (CMR) quantification technique to address challenges and technical limitations for MBF CMR. By developing and validating novel techniques to improve first-pass perfusion (FPP) cardiac MR, we propose to increase diagnostic accuracy by minimizing false positives and false negatives, allow for better evaluation and accurate quantification of total ischemic burden and reduce imag... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2023
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Coronary Artery Disease, Coronary Microvascular Disease
Register for Updates
ZZ06 in Adult Patients With Advanced EGFR Positive Solid Tumor Malignancies
NCT04412616
Recruiting
This is a Phase 1, Multicenter, Open-label study to assess the safety, tolerability and preliminary efficacy of ZZ06 in participants with all Adult Patients with Advanced EGFR-positive Solid Tumor Malignancies who are not able to have current standard anti-tumor therapies. The purpose of this study is to determine the maximum tolerated dose (MTD) , to characterise the safety, pharmacokinetics (PK), immunogenicity, pharmacodynamics (PD) and anti-tumor activity of ZZ06 as a single agent in adult p... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2023
Locations: Cedars Sinai Medical Center, Los Angeles, California
Conditions: Advanced EGFR Positive Solid Tumor
Register for Updates
Genetic, Metabolic, and Growth Factor Repository for Cerebrovascular Disorders
NCT02910180
Recruiting
This study encompasses the maintenance and utilization of a repository of samples from patients with cerebrovascular disease and stroke. The types of tissue taken are blood, cerebrospinal fluid (CSF), tissue, and microdialysis samples. Future analysis of these samples can potentially help investigators to better categorize groups of patients, understand the underlying etiology of these pathologies, identify markers that are associated with favorable or poor outcomes, and track changes that occur... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2023
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Cerebrovascular Diseases, Ischemic Stroke, Repository
Register for Updates
Allograft Adipose Injectable for Vocal Fold Paralysis
NCT04700566
Recruiting
Renuva is allograft adipose matrix commonly used as a filler in cosmetic procedures. The investigators are studying this material as an injectable in the vocal fold to treat glottic insufficiency. Currently, many products can be used as an injectable in the vocal fold to correct glottic insufficiency such as carbomethycellulose, hyaluronic acid, collagen derivatives and calcium hydroxyapatite amongst others. An ideal injectable would not impair the fibroelastic property of the vocal fold tissu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/02/2023
Locations: University of Southern California, Los Angeles, California
Conditions: Vocal Fold Palsy
Register for Updates
A Study of Navicixizumab Monotherapy or in Combination in Patients With Select Advanced Solid Tumors
NCT05453825
Recruiting
This is a study of navicixizumab monotherapy or in combination with paclitaxel or irinotecan in patients with advanced cancer. Patients will be enrolled into one of the following cancer cohorts: Cohort A: CRC Cohort B: Gastric and GEJ cancer Cohort C: TNBC Cohort D: Platinum-resistant/refractory epithelial ovarian, primary peritoneal, or fallopian tube cancer (ovarian cancer)
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2023
Locations: Keck Medicine of USC, Los Angeles, California
Conditions: Colorectal Cancer, Triple Negative Breast Cancer, Gastric Cancer, Ovarian Cancer
Register for Updates
Open Label Study for the Use of Transcranial Ultrasound Treatment of Tremor
NCT05475340
Recruiting
The purpose of this Phase I open label study is to evaluate longer term tolerability and potential effectiveness of transcranial ultrasound in people with tremor as a results of Parkinson's Disease or Essential Tremor.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
01/25/2023
Locations: Neurological Associates of West Los Angeles, Los Angeles, California
Conditions: Tremor, Parkinson Disease, Essential Tremor
Register for Updates