There are currently 697 clinical trials in San Diego, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California, San Diego, Rady Children's Hospital - San Diego, GSK Investigational Site and Naval Medical Center - San Diego. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Effects of Watermelon or Low-fat Cookie Consumption on Wellness
Recruiting
The objective of the proposed research is to determine the effects of fresh watermelon consumption on physiological indicators of wellness regarding sexual, skin and gut health in adults.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
03/26/2025
Locations: School of Exercise and Nutritional Sciences, San Diego, California
Conditions: Overweight and Obesity
An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants with Chronic Thyroid Eye Disease (TED)
Recruiting
This is a clinical trial assessing the efficacy, safety, and tolerability of an investigational drug, VRDN-003, in participants with chronic Thyroid Eye Disease (TED).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/26/2025
Locations: Senta Clinic, San Diego, California
Conditions: Thyroid Eye Disease
Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery
Recruiting
Apply CT angiography, CT perfusion imaging and advanced image processing techniques to improve revascularization decision-making and surgical strategies in patients undergoing coronary artery bypass graft surgery.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
03/25/2025
Locations: University of California San Diego, San Diego, California
Conditions: CAD, Atheroscleroses, Coronary, Computed Tomography, Coronary Artery Bypass
Natural History Study of Patients with HPDL Mutations
Recruiting
This study uses medical records that allow retrospective data extraction of clinical manifestation to assess the natural history of HPDL mutations
Gender:
ALL
Ages:
All
Trial Updated:
03/25/2025
Locations: Eun Hae Lee, San Diego, California
Conditions: Mitochondrial Encephalomyopathies, Hereditary Spastic Paraplegia, Spastic Paraplegia, White Matter Disease, Neonatal Encephalopathy, Mutation, Genetic Disease
InfasurfAero™ Versus Sham Treatment in Preterm Newborns with RDS
Recruiting
The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAero™, a novel oral airway delivery device specifically designed to give Infasurf in a less complicated way and without the need for a breathing tube or interrupting nasal respiratory support.
Gender:
ALL
Ages:
Between 29 weeks and 36 weeks
Trial Updated:
03/25/2025
Locations: Sharp Mary Birch Hospital for Women & Newborns, San Diego, California
Conditions: Respiratory Distress Syndrome (Neonatal), Intubation Complication, Death; Neonatal
An INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY to ASSESS the PERFORMANCE of the CORDIO HEARO SYSTEM
Recruiting
Study Design: This is an international, multicenter, observational, non-interventional, prospective, blinded, single-arm, two-period study, to collect patient utterances that will be retrospectively analyzed to determine the sensitivity and UPNR of the HearO system.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/25/2025
Locations: VA San Diego, San Diego, California
Conditions: Heart Failure
Ketogenic Diet and Brain Response in Anorexia Nervosa
Recruiting
This is a longitudinal study with an open design in weight recovered anorexia nervosa (wrAN) individuals. Healthy controls (HC) will also be assessed. Study participants will be carefully assessed and will have 18F-fluorodeoxyglucose (\[18F\]FDG) positron emission tomography (PET) scans for assessment of regional brain glucose uptake. The wrAN group will be compared to healthy controls. Participants in the wrAN group will then complete 14 weeks of therapeutic ketogenic diet (TKD). At the end of... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
03/25/2025
Locations: University of California San Diego, San Diego, California
Conditions: Anorexia Nervosa
Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)
Recruiting
This is a two-site randomized clinical trial aiming to test whether a modified investigational bariatric surgical procedure can improve gastroesophageal reflux disease (GERD) after sleeve gastrectomy.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
03/25/2025
Locations: University of California, San Diego, San Diego, California
Conditions: Obesity, Bariatric Surgery, Sleeve Gastrectomy, Gastroesophageal Reflux Disease
Families, Responsibility, Education, Support, and Health for Executive Function
Recruiting
The pilot study will be a one group open-label treatment program and will be used to refine a parent-based behavioral treatment enhanced with executive-function training (PBT-EF) for children with comorbid overweight or obesity and Attention-Deficit Hyperactivity Disorder (ADHD).
Gender:
ALL
Ages:
Between 8 years and 12 years
Trial Updated:
03/24/2025
Locations: UCSD Center for Healthy Eating and Activity Research (CHEAR), San Diego, California
Conditions: Overweight and Obesity, Attention-Deficit Hyperactivity Disorder
Beta-Agonist Versus OnabotulinumtoxinA Trial for Urgency Urinary Incontinence
Recruiting
The goal of this clinical trial is to compare treatment outcomes between an oral medication (beta agonist) versus onabotulinumtoxinA injections in women with urgency urinary incontinence (UUI). Participants will be randomly selected to receive one of the two treatments. The primary outcome measure will be at 3 months, and women will be followed for a total of 12 months. Based on patient expert input, there are 2 primary outcomes: Treatment satisfaction and urinary symptom severity.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: University of California, San Diego, San Diego, California
Conditions: Urgency Urinary Incontinence
Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA
Recruiting
The purpose of this study is to evaluate the safety and efficacy of narsoplimab in pediatric patients with thrombotic microangiopathies (TMA) following hematopoietic stem cell transplant (HSCT).
Gender:
ALL
Ages:
Between 28 days and 17 years
Trial Updated:
03/24/2025
Locations: Omeros Investigational Site, San Diego, California
Conditions: Thrombotic Microangiopathies, Hematopoietic Stem Cell Transplantation
Dose Exploration Study of GSK4532990 in. Participants With NASH or Suspected NASH
Recruiting
The purpose of this study is to understand how the drug GSK4532990 is processed in the body (pharmacokinetics) and how it works in the liver (pharmacodynamics) as well as to ensure it is safe and well-tolerated. The total study duration for each participant will be approximately 24-36 weeks.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/24/2025
Locations: GSK Investigational Site, San Diego, California +1 locations
Conditions: Non-alcoholic Fatty Liver Disease