There are currently 696 clinical trials in San Diego, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California, San Diego, Rady Children's Hospital - San Diego, GSK Investigational Site and Naval Medical Center - San Diego. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Dose-Optimized and Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression
NCT06730841
Recruiting
This study aims to evaluate the feasibility, safety, and tolerability of an innovative approach to treating Major Depressive Disorder (MDD), particularly in cases where patients have not responded well to traditional therapies. Specifically, the objective is to evaluate the antidepressant effects of a Dose-Optimized and Spaced Transcranial Direct Current Stimulation (DOS-tDCS) protocol in participants with treatment-resistant depression (TRD) compared to spaced tDCS only and sham tDCS in a 3-arm... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
12/11/2024
Locations: UCSD Interventional Psychiatry, San Diego, California
Conditions: Treatment Resistant Depression, Major Depressive Disorder
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MYTHS - MYocarditis THerapy With Steroids
NCT05150704
Recruiting
This is a phase III, multi-center international, single blind randomized controlled trial to test the efficacy of pulsed intravenous (IV) methylprednisolone versus standard therapy on top of maximal support in patients with Acute myocarditis (AM).
Gender:
ALL
Ages:
Between 18 years and 69 years
Trial Updated:
12/10/2024
Locations: University of California San Diego, San Diego, California
Conditions: Myocarditis Acute
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Phase 1 Study of INBRX-109 in Subjects with Locally Advanced or Metastatic Solid Tumors Including Sarcomas
NCT03715933
Recruiting
This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody targeting the human death receptor 5 (DR5).
Gender:
ALL
Ages:
Between 12 years and 85 years
Trial Updated:
12/09/2024
Locations: University of California, San Diego (UCSD) - Moores Cancer Center, San Diego, California
Conditions: Colorectal Adenocarcinoma, Ewing Sarcoma
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Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors
NCT03803423
Recruiting
This study utilizes a web-based application to help patients on the organ transplant waitlist communicate patient's need for a living donor via social media and provide interested potential donors the opportunity to engage with the evaluation process.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: Scripps Green Hospital, San Diego, California
Conditions: End Stage Renal Disease, End Stage Liver Disease
Register for Updates
Blood Pressure Effects on Cognition and Brain Blood Flow in PD
NCT05400174
Recruiting
Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. Besides causing symptoms that impair movement, PD also causes non-motor symptoms, such as problems thinking and orthostatic hypotension (OH), i.e., low blood pressure (BP) when standing. About one-third of people with PD have OH, which can cause sudden, temporary symptoms while upright, including lightheadedness, dizziness, and fainting. People with PD and OH can also experience problems thinking that happen... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
12/03/2024
Locations: University of California San Diego, San Diego, California
Conditions: Parkinson Disease, Orthostatic Hypotension, Dysautonomia
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Improving Psychological and Vestibular Health: MINDGAPS
NCT05986279
Recruiting
The purpose of this study is twofold: 1) Develop norms for measures of inner ear function and psychological health, and 2) Examine the feasibility of using the MINDGAPS system (a remote monitoring system) to track progress during physical therapy or rehabilitation for inner ear problems following a concussion or mild Traumatic Brain Injury.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: Naval Medical Center San Diego, San Diego, California
Conditions: Vestibular Hypofunction
Register for Updates
Women Focused Encounters for Resilience Independence Strength and Eudaimonia
NCT06216600
Recruiting
The goal of this combination Type 1 hybrid and observational study is to evaluate the impact of a peer delivered intervention of acceptance and comittment therapy(ACT) + exercise + social support to address the substance (ab)use, violence, and AIDS/HIV (SAVA) to improve medication adherence for women living with HIV (WLWH). This intervention will be implemented by community based organizations that focus on WLWH across four counties. The main question it aims to answer are: * Will peer provisio... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: UC San Diego AntiViral Research Center (AVRC), San Diego, California
Conditions: HIV Infections, Substance Use, Trauma, Medication Adherence
Register for Updates
Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG)
NCT06721975
Recruiting
This research study is being conducted to assess the ability and efficiency of two laser systems to break up kidney stones during ureteroscopy with laser lithotripsy for kidney stone treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of California, San Diego, San Diego, California
Conditions: Kidney Stones, Nephrolithiasis
Register for Updates
Evaluation of the Effects of a Rehabilitation Program in Individuals with Spine Pain
NCT04081896
Recruiting
SpineZone is an innovative physical therapy program with its focus on treatment of cervical, thoracic, and lumbar conditions through the use of a multi-disciplinary, technology enabled platform. Standard physical therapy modalities including psychologically informed physical therapy are employed in addition to online coaching with a fundamental tenant of core strengthening. Treatments are tracked and modified in a multi-disciplinary format taking all radiographic studies into direct consideratio... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
11/26/2024
Locations: SpineZone, San Diego, California
Conditions: Neck Pain, Low Back Pain, Scoliosis, Thoracic Injuries
Register for Updates
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
NCT04916210
Recruiting
The overall goal of the DISCOVERY study is to better understand what factors contribute to changes in cognitive (i.e., thinking and memory) abilities in patients who experienced a stroke. The purpose of the study is to help doctors identify patients at risk for dementia (decline in memory, thinking and other mental abilities that significantly affects daily functioning) after their stroke so that future treatments may be developed to improve outcomes in stroke patients. For this study, a "stroke... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/25/2024
Locations: University of California San Diego, San Diego, California
Conditions: Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Dementia, Vascular, Mild Cognitive Impairment, Vascular Cognitive Impairment
Register for Updates
HIV/STD Risk and PrEP Implementation Messaging Among Gay, Bisexual, and Other Men Who Have Sex with Men
NCT06183502
Recruiting
The goal of this observational study is to learn about awareness around PrEP use and adherence, condom use, sexual risk-taking behavior, and substance-using behaviors in men having sex with men. The main objective is to study a prospective cohort of MSM in Atlanta, Chicago, and San Diego to understand men's strategies to prevent HIV/Sexually Transmissible Infections (STIs), including PrEP use and adherence, condom use, sexual risk-taking behavior, and substance-using behaviors Participants will... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/25/2024
Locations: San Diego State University, San Diego, California
Conditions: Sexually Transmitted Infections, Gay, Pre Exposure Prophylaxis
Register for Updates
Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)
NCT06277037
Recruiting
This is a long term follow-up study for chronic hepatitis B (CHB) subjects who have received imdusiran treatment in a prior clinical trial, stopped NA therapy during that trial, and remain off therapy. Subjects may enroll after completing the end of study visit (baseline visit within 12 weeks ± 1 week from the end of study \[EOS\] visit) from their imdusiran clinical trial (the "parent study"). No interventions will be performed in this study other than blood sample collections, review of curren... Read More
Gender:
ALL
Ages:
Between 20 years and 70 years
Trial Updated:
11/25/2024
Locations: Research and Education Inc., San Diego, California
Conditions: Long Term Follow-up
Register for Updates