The state of California currently has 85 active clinical trials seeking participants for Healthy research studies. These trials are conducted in various cities, including Los Angeles, San Francisco, San Diego and Sacramento.
A Study of LY3971297 in Healthy Participants
NCT06148272
Recruiting
The purpose of this study is to measure side effects of LY3971297 injection administered under the skin in healthy participants and obese participants with high blood pressure (BP). Blood tests will be performed to check how much LY3971297 gets into the bloodstream and how long it takes the body to eliminate it. This is a 7-part study. The study duration will be approximately 60 days for Parts A and F, and approximately 90 days for Parts B, C, D, E, and G.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/23/2025
Locations: CenExel ACT, Anaheim, California
Conditions: Healthy, Obesity, Hypertension
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Hair Biomarkers Study
NCT07011082
Recruiting
Young children aged 0-4 years may be exposed to adverse childhood experiences (ACEs) and/or early life adversity (ELA), which are linked with worse physical and mental health across their lifespan. On the other hand, positive childhood experiences (PCEs) can build resilience and prevent or protect against these detrimental outcomes. Data analyses will assess the interactions of ACEs, PCEs, parenting, and poverty on the early social psychology of childhood and develop objective measures for alter... Read More
Gender:
ALL
Ages:
Between 6 months and 24 months
Trial Updated:
06/18/2025
Locations: Stanford University, Palo Alto, California
Conditions: Healthy
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A Study to Assess the Impact of Multiple Doses of AZD6234 on a Single Dose of Combined Oral Contraceptive in Female Participants
NCT07013643
Recruiting
This study will assess the effect of multiple doses of AZD6234 on the effect of single doses of combined oral contraceptive ethinyl estradiol (EE)/levonorgestrel (LEVO) in healthy female participants with overweight or obesity.
Gender:
FEMALE
Ages:
Between 35 years and 75 years
Trial Updated:
06/17/2025
Locations: Research Site, Glendale, California
Conditions: Healthy Participants
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A Study of LY4268989 (MORF-057) in Healthy Participants
NCT06964776
Recruiting
The purpose of this study is to measure the body's absorption and processing of the study drug, the study drug's effect on the body, safety, and tolerability with LY4268989 (MORF-57) in healthy participants, including Japanese and Chinese participants
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/16/2025
Locations: CenExel ACT, Anaheim, California
Conditions: Healthy
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A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels
NCT06980428
Recruiting
The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of single and multiple ascending doses of AZD4954 in healthy participants with or without elevated Lipoprotein(a) (Lp\[a\]) levels.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
06/16/2025
Locations: Research Site, Glendale, California
Conditions: Healthy Participants
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A First-in-Human Single and Multiple Ascending Dose Study of MT-501
NCT06762457
Recruiting
First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) with Single and Multiple Ascending Oral Doses of MT-501 in Healthy Adults.
Gender:
ALL
Ages:
Between 19 years and 55 years
Trial Updated:
06/13/2025
Locations: Mirador Clinical Department, San Diego, California
Conditions: Healthy Volunteers
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A Study of LY3867070 in Healthy Participants
NCT07021547
Recruiting
The purpose of this study is to evaluate how well LY3867070 is tolerated and what side effects may occur in healthy participants. The study drug will be administered orally. Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/13/2025
Locations: Anaheim Clinical Trials, LLC, Anaheim, California
Conditions: Healthy
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A Single and Multiple Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of AZD8965 in Healthy Participants (Including Japanese and Chinese Participants) and an Open-label Cohort to Assess the Effect of Food on the Pharmacokinetics of AZD8965 in Healthy Participants
NCT06502379
Recruiting
The purpose of this study is to assess the safety, tolerability, and pharmacokinetics (PK) of AZD8965 via single and multiple ascending doses in healthy participants (including Japanese and Chinese participants), and to assess the effect of food on the safety, tolerability, and PK of orally administered AZD8965.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
06/12/2025
Locations: Research Site, Glendale, California
Conditions: Healthy Participants
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A Study of Sotatercept (MK-7962) in Healthy Females Administered as a Liquid Formulation in an Autoinjector Versus the Lyophilized Formulation (MK-7962-027)
NCT06930664
Recruiting
The goal of the study is to learn what happens to different forms of sotatercept medications in a healthy person's body over time. Researchers want to know if there is a difference in the healthy person's body when different forms of sotatercept medications are given.
Gender:
FEMALE
Ages:
Between 18 years and 85 years
Trial Updated:
06/12/2025
Locations: Anaheim Clinical Trials ( Site 0007), Anaheim, California
Conditions: Healthy
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A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B)
NCT06349473
Recruiting
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) of SR604 in healthy participants (Part A) and to evaluate the safety, tolerability, PK, PD, and efficacy of SR604 in participants with Hemophilia A or Hemophilia B, with or without inhibitors (Part B).
Gender:
MALE
Ages:
Between 18 years and 60 years
Trial Updated:
06/11/2025
Locations: California Clinical Trials Medical Group (CCTMG), Glendale, California +1 locations
Conditions: Healthy Participants, Hemophilia A, Hemophilia B
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A Study to Evaluate the Effects of Lithium and Valproic Acid on the Pharmacokinetics of KarXT and Effects of KarXT on the Pharmacokinetics of Lithium and Valproic Acid in Healthy Participants
NCT06729970
Recruiting
The purpose of this study is to evaluate the effects of lithium and valproic acid on the single-dose pharmacokinetics (PK) of KarXT and the effect of KarXT on the single-dose PK of lithium and valproic acid in healthy participants.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/10/2025
Locations: CenExel Collaborative Neuroscience Research, LLC - Los Alamitos, Los Alamitos, California
Conditions: Healthy Volunteers
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An Accessorised Prefilled Syringe to an Autoinjector Pharmacokinetic Bridging Study of Tozorakimab
NCT06908577
Recruiting
The purpose of this study is to compare the pharmacokinetic (PK) exposures of a single subcutaneous (SC) dose of tozorakimab administered using AI or APFS in healthy participants.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
06/09/2025
Locations: Research Site, Glendale, California
Conditions: Healthy Participants
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