There are currently 443 active clinical trials seeking participants for Breast Cancer research studies. The states with the highest number of trials for Breast Cancer participants are California, Ohio, Illinois and Michigan.
Piloting Y-AMBIENT: a Quality of Life Intervention for Young African American Breast Cancer Survivors
Recruiting
The purpose of this two-arm pilot RCT is to evaluate processes and preliminary outcomes of a targeted QOL intervention vs. an attention control among young AA survivors post-treatment for early (I-II) \& late (III) stage breast cancer.
Gender:
FEMALE
Ages:
Between 18 years and 44 years
Trial Updated:
03/17/2025
Locations: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Conditions: Breast Cancer, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8
Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
Recruiting
Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/03/2025
Locations: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Conditions: Breast Cancer
Feasibility Study of CBCT for IGRT in Cancer Patients
Recruiting
Cone beam computed tomography (CBCT) is an imaging technology that is incorporated into many modern radiation therapy systems. The quality of conventional CBCT is good enough to align patients for their daily radiation therapy but CBCT images have poor contrast and are susceptible to imaging artefacts that limit their usability for other tasks in the radiation therapy workflow. Varian Medical Systems, the sponsor of this study, has developed new CBCT imaging technology called HyperSight that so... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/28/2025
Locations: The Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, Ohio +1 locations
Conditions: Head and Neck Cancers, Breast Cancer, Thoracic Cancers, Liver Cancer, Genito Urinary Cancer, Gastrointestinal Cancers
Inspiratory Muscle Training in Obese Breast Cancer Survivors
Recruiting
The investigators propose a randomized controlled trial to determine the effectiveness of inspiratory muscle training in improving exercise tolerance among stage 0-III obese breast cancer survivors.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/27/2024
Locations: The Ohio State University, Columbus, Ohio
Conditions: Cancer Survivors, Obesity, Breast Cancer
IORT Following Breast Conserving Surgery for Early Stage Breast Cancer Registry
Recruiting
This is a prospective, registry trial which will enroll women aged 65 and above with early stage, low risk breast cancer who will be treated with partial mastectomy and intraoperative radiation therapy (IORT). The primary aim is to determine the 5-year risk of in-breast tumor recurrence. Secondary aims include identification of acute- and late-toxicity, cosmetic result, disease-free survival and overall survival.
Gender:
FEMALE
Ages:
65 years and above
Trial Updated:
11/25/2024
Locations: Mount Carmel West Hospital, Columbus, Ohio
Conditions: Breast Cancer
CFI-402257, a Potent and Selective TTK Inhibitor, in Solid Tumors and With Fulvestrant in Breast Cancer
Recruiting
The purpose of this study is to test the safety of an investigational drug called CFI-402257 alone in advanced solid tumors and in combination with Fulvestrant in advanced breast cancer patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/16/2024
Locations: The Ohio State University Comprehensive Cancer Center, Columbus, Ohio +3 locations
Conditions: Advanced Solid Tumor, Breast Cancer
Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer
Recruiting
Breast cancer (BC) is the most frequently diagnosed cancer in women. Systemic cancer treatments are an important contributor to dramatic improvements in the long-term survival of women with BC. However, cancer treatment can lead to cognitive impairment and declines in quality of life in women with BC. Many cancer survivors experience memory and brain function decline following chemotherapy which can last for years. A newer diet pattern, Mediterranean-DASH \[Dietary Approaches to Stop Hypertensio... Read More
Gender:
FEMALE
Ages:
Between 45 years and 75 years
Trial Updated:
08/30/2024
Locations: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Conditions: Breast Cancer
Interventional Program Educates, Identifies + Overcomes Barriers to Complete Screening Mammography
Recruiting
The purpose of this study is to identify interventions that are designed to better serve women who are homeless, with a specific focus on increasing screening rates and decreasing late stage breast cancer diagnosis among this high-risk understudied community of women. As a result, the study team hopes to influence the broader homeless healthcare initiative
Gender:
FEMALE
Ages:
40 years and above
Trial Updated:
03/03/2025
Locations: Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio
Conditions: Breast Cancer
Patient Recall of Cancer Screening and Diagnosis
Recruiting
The purpose of this research is to try to better understand how much information relating to cancer screening and diagnoses that people can recall on their own and to better understand how to help people get better information. In this study, investigators will see if giving time or other resources help individuals remember more and more accurate details about their cancer screening and care.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/06/2025
Locations: Case Comprehensive Cancer Center, Cleveland, Ohio
Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast
Recruiting
The standard treatment for participants whose cancer has returned after breast conserving surgery is radiation given twice daily (separated by at least 6 hours) for a total of 30 treatments. The purpose of this study is to find out if giving radiation once a day for 15 treatments after repeat breast conserving surgery works as well as giving it the standard way.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
12/11/2024
Locations: University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio +1 locations
Conditions: Breast Cancer, Tumor, Breast
NAVAH Impact on Radiation Therapy Completion in Black Breast & Prostate Cancer Patients
Recruiting
African-Americans have disparately limited access to optimal cancer care. They have the highest overall cancer death rate and shortest survival time of any racial or ethnic group in the United States. Elucidation of disparities in access to cancer care are important since previous work has indicated that when equal access to RT in Radiation Therapy Oncology Group (RTOG) prospective randomized trials is granted, race does not independently affect outcomes, a finding similar to work conducted in L... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio
Breast Margin Study: Routine Cavity Shave Margins Vs. Selective Margins Using Savi Scout®
Recruiting
This is a prospective study comparing partial mastectomy performed with routine cavity shave margins and Savi Scout® localization to partial mastectomy performed with selective margins and Savi Scout® localization. The primary objective is to determine the difference in positive margin rate between the two methods. The secondary objectives are to determine the differences in the rate of re-excision, volume of tissue extracted and Breast-Q® score between the two methods. It is hypothesized that t... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/26/2024
Locations: Cleveland Clinic Akron General, Case Comprehensive Cancer Center, Akron, Ohio
Conditions: Breast Cancer