There are currently 486 active clinical trials seeking participants for Breast Cancer research studies. The states with the highest number of trials for Autism participants are California, Ohio, Illinois and Michigan.
CFI-402257, a Potent and Selective TTK Inhibitor, in Solid Tumors and With Fulvestrant in Breast Cancer
Recruiting
The purpose of this study is to test the safety of an investigational drug called CFI-402257 alone in advanced solid tumors and in combination with Fulvestrant in advanced breast cancer patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/08/2024
Locations: The Ohio State University Comprehensive Cancer Center, Columbus, Ohio +3 locations
Conditions: Advanced Solid Tumor, Breast Cancer
Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
Recruiting
Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Conditions: Breast Cancer
Inspiratory Muscle Training in Obese Breast Cancer Survivors
Recruiting
The investigators propose a randomized controlled trial to determine the effectiveness of inspiratory muscle training in improving exercise tolerance among stage 0-III obese breast cancer survivors.
Gender:
Female
Ages:
18 years and above
Trial Updated:
11/14/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Cancer Survivors, Obesity, Breast Cancer
Remote Assessment of Cognition, Insulin Resistance and Omega-3 Fatty Acid Biomarkers in Breast Cancer Survivors
Recruiting
Majority of breast cancer survivors are overweight or obese at time of diagnosis, putting them at increased risk for insulin resistance and Type 2 Diabetes Mellitus (T2DM). Women with insulin resistance at time of breast cancer diagnosis often have larger tumors, later stages of cancer and worse prognosis. Additionally, chemotherapy often leads to increases in insulin resistance and cognitive impairment. Many cancer survivors experience memory and brain function decline following chemotherapy th... Read More
Gender:
Female
Ages:
Between 45 years and 75 years
Trial Updated:
10/25/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Breast Cancer, Obesity
IORT Following Breast Conserving Surgery for Early Stage Breast Cancer Registry
Recruiting
This is a prospective, registry trial which will enroll women aged 65 and above with early stage, low risk breast cancer who will be treated with partial mastectomy and intraoperative radiation therapy (IORT). The primary aim is to determine the 5-year risk of in-breast tumor recurrence. Secondary aims include identification of acute- and late-toxicity, cosmetic result, disease-free survival and overall survival.
Gender:
Female
Ages:
65 years and above
Trial Updated:
08/15/2023
Locations: Mount Carmel West Hospital, Columbus, Ohio
Conditions: Breast Cancer
Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer
Recruiting
Breast cancer (BC) is the most frequently diagnosed cancer in women. Systemic cancer treatments are an important contributor to dramatic improvements in the long-term survival of women with BC. However, cancer treatment can lead to cognitive impairment and declines in quality of life in women with BC. Many cancer survivors experience memory and brain function decline following chemotherapy which can last for years. A newer diet pattern, Mediterranean-DASH [Dietary Approaches to Stop Hypertension... Read More
Gender:
Female
Ages:
Between 45 years and 75 years
Trial Updated:
08/02/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Breast Cancer
A QoL Intervention for Young African American Breast Cancer Survivors
Recruiting
The purpose of this two-arm pilot RCT is to evaluate processes and preliminary outcomes of a targeted QOL intervention vs. an attention control among young AA survivors post-treatment for early (I-II) & late (III) stage breast cancer.
Gender:
Female
Ages:
Between 18 years and 44 years
Trial Updated:
02/06/2023
Locations: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Conditions: Breast Cancer, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8
Interventional Program Educates, Identifies + Overcomes Barriers to Complete Screening Mammography
Recruiting
The purpose of this study is to identify interventions that are designed to better serve women who are homeless, with a specific focus on increasing screening rates and decreasing late stage breast cancer diagnosis among this high-risk understudied community of women. As a result, the study team hopes to influence the broader homeless healthcare initiative
Gender:
Female
Ages:
40 years and above
Trial Updated:
04/02/2024
Locations: Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio
Conditions: Breast Cancer
Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast
Recruiting
The standard treatment for participants whose cancer has returned after breast conserving surgery is radiation given twice daily (separated by at least 6 hours) for a total of 30 treatments. The purpose of this study is to find out if giving radiation once a day for 15 treatments after repeat breast conserving surgery works as well as giving it the standard way.
Gender:
All
Ages:
19 years and above
Trial Updated:
03/04/2024
Locations: University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio +1 locations
Conditions: Breast Cancer, Tumor, Breast
Breast Margin Study: Routine Cavity Shave Margins Vs. Selective Margins Using Savi Scout®
Recruiting
This is a prospective study comparing partial mastectomy performed with routine cavity shave margins and Savi Scout® localization to partial mastectomy performed with selective margins and Savi Scout® localization. The primary objective is to determine the difference in positive margin rate between the two methods. The secondary objectives are to determine the differences in the rate of re-excision, volume of tissue extracted and Breast-Q® score between the two methods. It is hypothesized that t... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Cleveland Clinic Akron General, Akron, Ohio
Conditions: Breast Cancer
Effectiveness of AI Genetic Counseling Program vs In-person Genetic Counseling in Breast Cancer
Recruiting
The purpose of this study is to help better understand the uptake and impact of genetic testing for women diagnosed with breast cancer who do not meet National Comprehensive Cancer Network (NCCN) criteria for genetic testing. By doing so, the research team will gain a better understanding of the clinical implications for offering genetic testing for all patients recently diagnosed with breast cancer versus only offering genetic testing to those meeting NCCN criteria. By offering genetic counsel... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center, Cleveland, Ohio
Conditions: Breast Cancer
Patient Recall of Cancer Screening and Diagnosis
Recruiting
The purpose of this research is to try to better understand how much information relating to cancer screening and diagnoses that people can recall on their own and to better understand how to help people get better information. In this study, investigators will see if giving time or other resources help individuals remember more and more accurate details about their cancer screening and care.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/04/2023
Locations: Case Comprehensive Cancer Center, Cleveland, Ohio