There are currently 26 active clinical trials seeking participants for Generalized Anxiety Disorder research studies. The states with the highest number of trials for Generalized Anxiety Disorder participants are California, Florida, New York and Texas.
MBSR Mechanisms in GAD
NCT05064813
Recruiting
The purpose of this study is to understand the neural mechanisms that drive response to MBSR compared to stress education in patients with generalized anxiety disorder (GAD), and to examine the degree to which sex differences in MBSR response are explained by sex differences in these mechanisms. A total of 150 eligible participants with a primary diagnosis of GAD will be randomized to either an 8-week group MBSR or stress education program. The study will include preliminary screening, experimen... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
03/04/2025
Locations: NYU Langone Health, New York, New York
Conditions: Generalized Anxiety Disorder
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Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
NCT06701903
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety, and tolerability of ITI-1284 as monotherapy treatment in patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria for GAD in patients who have had inadequate response to generalized anxiety disorder treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: Clinical Site, Little Rock, Arkansas +14 locations
Conditions: Generalized Anxiety Disorder
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Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
NCT06480383
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled study evaluating the efficacy, safety, and tolerability of ITI-1284 compared with placebo as adjunctive therapy to GAD treatment in patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria for GAD who have an inadequate response to ongoing GAD treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: Clinical Site, Chandler, Arizona +29 locations
Conditions: Generalized Anxiety Disorder
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CES for the Treatment of GAD in Young Adults
NCT06124014
Recruiting
The purpose of this research study is to study cranial electrotherapy stimulation (CES) to determine its effects on symptoms of anxiety in people with generalized anxiety disorder (GAD) between the ages of 18 - 21 years of age.
Gender:
ALL
Ages:
Between 18 years and 21 years
Trial Updated:
02/11/2025
Locations: Carolina Center for Neurostimulation, Chapel Hill, North Carolina
Conditions: Generalized Anxiety Disorder
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Use of CBD in the Treatment of Anxiety
NCT06672666
Recruiting
This study will examine the doses, safety, and test the preliminary efficacy of hemp-derived CBD product for improving anxiety symptoms and sleep disturbances among individuals with anxiety. A 4-week, randomized, double-blind, placebo-controlled trial will be conducted to determine the safety, tolerability, preliminary efficacy, and acceptability of 50 to 150 mg/day of CBD. The treatment period will consist of a two-week titration period followed by a 2- week maintenance period. In addition, the... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
01/31/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Anxiety, Generalized Anxiety Disorder, Sleep Problems
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Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
NCT06376734
Recruiting
Participants will receive Transcranial Magnetic Stimulation (TMS) at a random location in the left prefrontal cortex, excluding sites that are potentially unsafe. Extensive behavioral testing will be conducted to determine which behaviors are modulated by stimulating which circuits.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/30/2025
Locations: Acacia Clinics, Sunnyvale, California +1 locations
Conditions: Major Depressive Disorder, Obsessive-Compulsive Disorder, Schizophrenia, Generalized Anxiety Disorder, Mood Disorders, Psychiatric Disorder, Mental Disorder, Depression, Anxiety
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Level of Physical Activity and Fear Learning
NCT05203731
Recruiting
The proposed experimental study will be the first to investigate whether exercise vs. sitting enhances consolidation of extinction learning in adults with high AS and anxiety disorders, and the mechanistic pathways of expectancy, affect, and key stress response markers.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
01/14/2025
Locations: NYU Langone Health, New York, New York
Conditions: Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
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Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity
NCT05117255
Recruiting
This project is designed to determine if a computer-delivered cognitive-behavioral treatment can improve the otherwise poor alcohol use disorder treatment outcomes for individuals with a co-occurring anxiety disorder. In the past, the investigators showed that this treatment does improve outcomes for these individuals when delivered by a therapist. If the present work shows that the computer-delivered version is also effective, it would provide an inexpensive program with virtually unlimited sca... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/11/2024
Locations: Lodging Plus Program, Fairview Hospital, Minneapolis, Minnesota
Conditions: Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Alcohol Use Disorder, Depression
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A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants with Generalized Anxiety Disorder (GAD)
NCT06051721
Recruiting
The purpose of this proof-of-concept trial is to examine the safety, tolerability, and pharmacokinetics (PK), and preliminary clinical efficacy of CYB004 participants with GAD.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/08/2024
Locations: Innovative Clinical Research, Inc., Miami Lakes, Florida +3 locations
Conditions: Generalized Anxiety Disorder
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Massage for GAD: Neuroimaging and Clinical Correlates of Response
NCT06506253
Recruiting
This clinical trial will compare the effects of Swedish massage or light touch therapy on brain activity and symptoms of anxiety. This is a randomized research study and subjects will be randomized into one of two study touch intervention groups, and will have an equal chance of being placed in one of the groups: 1. Swedish massage therapy twice per week for 6 weeks. 2. Light touch therapy twice per week for 6 weeks. The Primary Objective is to identify brain networks activated by touch inter... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
09/15/2024
Locations: Huntsman Mental Health Institute, Salt Lake City, Utah
Conditions: Generalized Anxiety Disorder
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ENCALM: a Study of ENX-102 As a Monotherapy Treatment in Patients with Generalized Anxiety Disorder
NCT05749055
Recruiting
The ENCALM trial is designed to evaluate the efficacy and safety of ENX-102 in patients diagnosed with generalized anxiety disorder (GAD)
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/29/2024
Locations: IMA Clinical Research Phoenix, Phoenix, Arizona +31 locations
Conditions: Generalized Anxiety Disorder
Register for Updates
Triage Survey for Psychiatry Research Eligibility
NCT05800925
Recruiting
TRIAGE-Psych is a survey study designed to assess potential participants' eligibility to screen for industry-sponsored psychiatry clinical trials.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/19/2023
Locations: Copley Clinical, Boston, Massachusetts +2 locations
Conditions: Major Depressive Disorder, Borderline Personality Disorder, Generalized Anxiety Disorder
Register for Updates