There are currently 26 active clinical trials seeking participants for Generalized Anxiety Disorder research studies. The states with the highest number of trials for Generalized Anxiety Disorder participants are California, Florida, New York and Texas.
Acceptability/Feasibility of IU Intervention
Recruiting
Anxiety disorders are prominent mental health burdens, affecting roughly 1 in 5 adults annually, and a third of individuals over the course of their life. These disorders are also impairing to individuals, with 23% of individuals with anxiety disorders describing their impairment as serious. Given the public health impact, it is crucial that interventions are designed to alleviate symptoms of anxiety, through reducing risk factors that predispose individuals to develop anxiety. One approach to d... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/13/2021
Locations: Ohio University, Athens, Ohio
Conditions: Generalized Anxiety Disorder, Emotional Disorder
MBSR Mechanisms in GAD
Recruiting
The purpose of this study is to understand the neural mechanisms that drive response to MBSR compared to stress education in patients with generalized anxiety disorder (GAD), and to examine the degree to which sex differences in MBSR response are explained by sex differences in these mechanisms. A total of 150 eligible participants with a primary diagnosis of GAD will be randomized to either an 8-week group MBSR or stress education program. The study will include preliminary screening, experimen... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
01/28/2025
Locations: NYU Langone Health, New York, New York
Conditions: Generalized Anxiety Disorder
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (VOYAGE)
Recruiting
A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating MM120 Compared to Placebo in Generalized Anxiety Disorder - Voyage
Gender:
ALL
Ages:
Between 18 years and 74 years
Trial Updated:
01/24/2025
Locations: Lighthouse Psychiatry, Gilbert, Arizona +26 locations
Conditions: Generalized Anxiety Disorder
A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder
Recruiting
A clinical study that will meaure how well SEP-363856 works and how safe it is in adults with Generalized Anixety Disorder. This study will be accepting both male and female subjects between the ages of 18 years and 65 years old. The study will be held in Approximately 50 global study centers and approximately 15 additional centers for a separate Japan population. Participation in the study can be up to approximately 12 weeks.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/23/2025
Locations: Research Site #116, Huntsville, Alabama +67 locations
Conditions: Generalized Anxiety Disorder
Internet-delivered Cognitive-Behavioral Therapy for Adolescents with Autism and Anxiety
Recruiting
Anxiety is very common in autistic youth. Cognitive behavioral therapy (CBT) is the recommended treatment for both autistic and typically-developing (TD) youth with anxiety, yet most families cannot access CBT due to cost, practicalities of attending in-person treatment sessions, and a shortage of trained providers, especially in rural areas. The goal of this project is to increase access to care for families of autistic adolescents with anxiety through an internet-based treatment model.
Gender:
ALL
Ages:
Between 11 years and 17 years
Trial Updated:
01/22/2025
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Autism Spectrum Disorder, Autism, Anxiety, Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder
Level of Physical Activity and Fear Learning
Recruiting
The proposed experimental study will be the first to investigate whether exercise vs. sitting enhances consolidation of extinction learning in adults with high AS and anxiety disorders, and the mechanistic pathways of expectancy, affect, and key stress response markers.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
01/14/2025
Locations: NYU Langone Health, New York, New York
Conditions: Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
Treating Young Adult Generalized Anxiety Disorder With Text-Message Delivered Cognitive Behavioral Therapy
Recruiting
The purpose of the proposed study is to test the feasibility and efficacy of a "anxiety-focused" text-delivered counseling program to reduce anxiety symptoms among young adults (18-25) with elevated anxiety symptoms. We are primarily interested in whether the intervention will reduce anxiety. We have adapted an effective in-person, manualized cognitive behavioral therapy treatment for anxiety (Muñoz et al, 2000) into an 8-week, text-delivered anxiety treatment, named CBT-txt-Anxiety. We will tes... Read More
Gender:
ALL
Ages:
Between 18 years and 25 years
Trial Updated:
01/08/2025
Locations: University of Tennessee-Knoxville, Knoxville, Tennessee
Conditions: Generalized Anxiety Disorder
Use of CBD in the Treatment of Anxiety
Recruiting
This study will examine the doses, safety, and test the preliminary efficacy of hemp-derived CBD product for improving anxiety symptoms and sleep disturbances among individuals with anxiety. A 4-week, randomized, double-blind, placebo-controlled trial will be conducted to determine the safety, tolerability, preliminary efficacy, and acceptability of 50 to 150 mg/day of CBD. The treatment period will consist of a two-week titration period followed by a 2- week maintenance period. In addition, the... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
12/18/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Anxiety, Generalized Anxiety Disorder, Sleep Problems
Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity
Recruiting
This project is designed to determine if a computer-delivered cognitive-behavioral treatment can improve the otherwise poor alcohol use disorder treatment outcomes for individuals with a co-occurring anxiety disorder. In the past, the investigators showed that this treatment does improve outcomes for these individuals when delivered by a therapist. If the present work shows that the computer-delivered version is also effective, it would provide an inexpensive program with virtually unlimited sca... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/11/2024
Locations: Lodging Plus Program, Fairview Hospital, Minneapolis, Minnesota
Conditions: Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Alcohol Use Disorder, Depression
Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety, and tolerability of ITI-1284 as monotherapy treatment in patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria for GAD in patients who have had inadequate response to generalized anxiety disorder treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2024
Locations: Clinical Site, Little Rock, Arkansas +14 locations
Conditions: Generalized Anxiety Disorder
Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled study evaluating the efficacy, safety, and tolerability of ITI-1284 compared with placebo as adjunctive therapy to GAD treatment in patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria for GAD who have an inadequate response to ongoing GAD treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2024
Locations: Clinical Site, Chandler, Arizona +27 locations
Conditions: Generalized Anxiety Disorder
Neurofeedback Enhanced Cognitive Reappraisal Training
Recruiting
This study seeks to understand emotion regulation in those with anxiety using real-time functional magnetic resonance imaging neurofeedback, a tool that allows individuals to control brain activity. The goal of this project is to understand how receiving feedback about one's own brain activity relates to emotion regulation ability. This work will help the study team understand the brain areas involved in emotion regulation and could lay the groundwork to test if psychotherapy outcomes can be enh... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
11/18/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Anxiety, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder