There are currently 57 active clinical trials seeking participants for Inflammation research studies. The states with the highest number of trials for Inflammation participants are California, Texas, Florida and New York.
Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc
NCT05236374
Recruiting
The objective of the current study is to test the overarching hypothesis that the beef nutritive matrix is uniquely suited to direct dietary zinc to cellular compartments for improved metabolic function, leading to a greater effect on health outcomes. Specifically, whether beef, as a component of a healthy meal, will promote the absorption of zinc into cells, where the zinc will have greater effects on zinc-dependent metabolic processes supporting cardiovascular health. To maximize the observabi... Read More
Gender:
ALL
Ages:
Between 55 years and 70 years
Trial Updated:
10/29/2024
Locations: University of California, Davis; Department of Nutrition, Davis, California
Conditions: Zinc Deficiency, Inflammation, Metabolic Diseases, Vascular Diseases
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Biomarkers in Infection
NCT02545478
Recruiting
The purpose of this investigation is to evaluate how early biomarkers of infection and inflammation perform in identifying patients at risk for poor outcome in sepsis and septic shock.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/27/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Sepsis, Infection, Inflammation
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ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation
NCT05021835
Recruiting
This study is conducted to see if ziltivekimab reduces the risk of having cardiovascular events (for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation. Participants will either get ziltivekimab (active medicine) or placebo (a dummy medicine which has no effect on the body). This is known as the study medicine. Which treatment participants get is decided by chance. Participants chance of getting ziltivekimab or placebo is the same. Z... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/12/2024
Locations: Uni of Alabama at Birmingham, Birmingham, Alabama +1057 locations
Conditions: Cardiovascular Risk, Chronic Kidney Disease, Inflammation
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Impact of NMES and HPRO on Recovery After SAH- Pilot Study
NCT03201094
Recruiting
The study purpose is to investigate the hypothesis that in adults with SAH, early neuromuscular electrical stimulation (NMES) and high protein supplementation (HPRO) will improve muscle mass, metabolic and inflammatory biomarker profiles, compared to SAH controls receiving standard of care interventions for nutrition and mobilization. The investigators will accomplish this by studying the effects of a high protein (HPRO) nutritional treatment as well as NMES intervention have upon muscle wasting... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Subarachnoid Hemorrhage, Muscle Atrophy, Inflammation, Nutritional and Metabolic Disease
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The Impact of a Race-Based Stress Reduction Intervention
NCT05902741
Recruiting
The goal of this clinical trial is to learn whether a stress reduction program called Resilience, Stress, and Ethnicity (RiSE) improves well-being, inflammation, and the epigenome in African American (AA) women who have risk factors for heart or metabolic disease. The main question it aims to answer is whether an intervention that integrates cognitive-behavioral strategies focused on the impact that social stress, such as racism, has on the body, racial identity development, and empowerment. P... Read More
Gender:
FEMALE
Ages:
Between 50 years and 75 years
Trial Updated:
10/08/2024
Locations: Loyola University Chicago, Maywood, Illinois
Conditions: Racism, Stress, Inflammation
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The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes
NCT06159543
Recruiting
The goal of this clinical trial is to test the effect of 12 weeks of 1.5 cups per day of fresh mango on glucose control, insulin resistance, lipids, inflammation, oxidation and body composition in individuals with prediabetes. The main questions it aims to answer are: * What is the effect of 1.5 cups per day of fresh mango over 12 weeks on indicators of glycemic control including fasting glucose and HgbA1c? * What is the effect of 1.5 cups per day of fresh mango over 12 weeks on fasting blood i... Read More
Gender:
ALL
Ages:
Between 40 years and 60 years
Trial Updated:
09/24/2024
Locations: Nutrition Research Center, School of Public Health, Loma Linda University, Loma Linda, California
Conditions: Hyperglycemia, Dyslipidemias, Insulin Resistance, Inflammation, Oxidative Stress
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Modulating Exercise Dosage to Improve Concussion Recovery
NCT05434130
Recruiting
Aerobic exercise has emerged as an effective treatment to reduce sport-related concussion symptom severity, yet existing work lacks rigor regarding the precise exercise volume and intensity required to elicit therapeutic effects, how exercise can alter concussion-related pathophysiology, and whether exercise can prevent the development of secondary sequelae. Our objective is to examine if a high dose exercise program (higher volume than currently prescribed at an individualized, safe intensity l... Read More
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
09/24/2024
Locations: University of Colorado Denver, Aurora, Colorado +2 locations
Conditions: Concussion, Brain, Treatment, Aerobic Exercise, Inflammation, Depression, Anxiety
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Aging and Reward System Response to Inflammation and Anxiety Study
NCT05363527
Recruiting
The purpose of this study is to use an experimental inflammatory challenge to examine whether older adults with symptoms of anxiety experience loss of pleasure or loss of motivation when they are exposed to inflammation. Loss of pleasure or loss of motivation will be evaluated using self-report questionnaires, computer tasks, and during a brain scan.
Gender:
ALL
Ages:
Between 60 years and 80 years
Trial Updated:
09/04/2024
Locations: Norman Cousins Center for Psychoneuroimmunology, University of California, Los Angeles, Los Angeles, California
Conditions: Anhedonia, Inflammation, Anxiety, Aging, Depression
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UCLA REST Study (REsearch on Sleep Techniques)
NCT05576090
Recruiting
Sleep disturbance has a range of negative effects on psychosocial and biological processes important for academic and social success as well as mental and physical health among adolescents and young adults. Limited, inconsistent, and poor quality sleep lead to anxiety, depressive feelings, loneliness, and fatigue over time. These symptoms, in turn, interfere with the ability to get a good night's rest. Sleep disruption can also upregulate inflammatory processes during the years of adolescence an... Read More
Gender:
ALL
Ages:
Between 18 years and 20 years
Trial Updated:
08/28/2024
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Sleep Disturbance, Inflammation, Psychosocial Functioning
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Relationship of Inflammation and Pulmonary Function to Fungal Translocation in HIV
NCT05502653
Recruiting
The investigator will study the origin of fungal translocation in HIV, its relationship to the mycobiome, and its relationship to lung function and inflammation. Supported by the preliminary data and published studies, this project is based on the premise that circulating BDG derived from microbial translocation stimulates inflammation and worsens lung function in PWH. Chronic obstructive pulmonary disease (COPD) is a significant public health problem with few therapies that modify disease traj... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/05/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: HIV Infections, Inflammation, COPD
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Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1
NCT04480554
Recruiting
HIV infection, as well as exposure to opioids (including heroin), are associated with systemic immune activation including increased microbial translocation from the gut. The overall objective of this study is to define the impact of long-term mu-opiate receptor stimulation or blockage with medication for opiate use disorder (i.e, methadone, buprenorphine/naloxone, or extended-release naltrexone) on the kinetics and extent of immune reconstitution on HIV-1 infected people who inject opiate and i... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/10/2024
Locations: University of Pennsylvania, Philadelphia, Pennsylvania +1 locations
Conditions: Opioid-use Disorder, HIV-1-infection, Immune Activation, Inflammation, Methadone, Buprenorphine, Naltrexone, Antiretroviral Treatment
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Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury
NCT04810858
Recruiting
This study applies a hypothesis-driven approach to examine the effects of chronic marijuana use on HIV-associated inflammation and its subsequent impacts on central nervous system function, with the goal of identifying the mechanisms through which cannabinoids modulate neurological disorders and other comorbidities in persons with HIV.
Gender:
ALL
Ages:
Between 25 years and 59 years
Trial Updated:
05/29/2024
Locations: Biotech Place, Winston-Salem, North Carolina
Conditions: Cannabis, HIV, Inflammation, Cognition, Neuroimaging
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