There are currently 54 active clinical trials seeking participants for Inflammation research studies. The states with the highest number of trials for Inflammation participants are California, Texas, New York and Florida.
Zinc Effect on Inflammation and Cardiovascular Risk in HIV
NCT05085834
Recruiting
To study the effect of short-term zinc supplementation on improving inflammation, metabolic, and cardiovascular risk among HIV infected patients on stable anti-retroviral therapy
Gender:
All
Ages:
18 years and above
Trial Updated:
06/28/2023
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Inflammation, Cardiovascular Diseases, Zinc Deficiency
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ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation
NCT05021835
Recruiting
This study is conducted to see if ziltivekimab reduces the risk of having cardiovascular events (for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation. Participants will either get ziltivekimab (active medicine) or placebo (a dummy medicine which has no effect on the body). This is known as the study medicine. Which treatment participants get is decided by chance. Participants chance of getting ziltivekimab or placebo is the same. Z... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: Uni of Alabama at Birmingham, Birmingham, Alabama +1056 locations
Conditions: Cardiovascular Risk, Chronic Kidney Disease, Inflammation
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Immune Cell Response to Stimuli
NCT00397280
Recruiting
This study will investigate the response of immune cells (neutrophils, monocytes) to various signals in the test tube to determine how they sense the signals in the body and what substances they produce in response to them. It will determine how the cells may, under certain circumstances, contribute to inflammation, and will measure substances in the blood plasma (the liquid, non-cellular part of the blood) that might stimulate white blood cells, in order to understand how the blood responds to... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/12/2024
Locations: NIEHS Clinical Research Unit (CRU), Research Triangle Park, North Carolina
Conditions: Inflammation
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Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity
NCT05017571
Recruiting
Background: About 40 percent of adults and 20 percent of adolescents in the U.S. have a body mass index over 30 kg/m2. Being overweight may lead to a state of low-level inflammation. This may cause health problems. Researchers want to see if an anti-inflammatory medicine can help. Objective: To learn if colchicine can improve metabolism in people who have high body weight, increased inflammation, and high insulin in the blood but who have not yet developed high blood sugar. Eligibility: Peo... Read More
Gender:
All
Ages:
Between 12 years and 100 years
Trial Updated:
06/11/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Obesity, Insulin Resistance, Inflammation
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The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies
NCT06454344
Recruiting
The overall purpose of this study is to understand the role of disrupted sleep in the association of exposure to early life adversity (adverse childhood experiences (ACEs)) with vascular endothelial (dys)function. In Aim 1 (The Iowa ACEs and Sleep Cohort Study), the investigators will utilize a cross-sectional cohort design with a state-of-the-art translational approach. Participants will be recruited to objectively characterize the degree to which lower sleep quality and quantity contribute to... Read More
Gender:
All
Ages:
Between 18 years and 29 years
Trial Updated:
06/09/2024
Locations: Integrative Laboratory of Applied Physiology and Lifestyle Medicine, Iowa City, Iowa
Conditions: Adverse Childhood Experiences, Vascular Dilatation, Sleep, Sleep Disturbance, Psychosocial Stressor, Psychological Trauma, Endothelial Dysfunction, Inflammation, Oxidative Stress
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WHNRC (Western Human Nutrition Research Center) Fiber Intervention Study
NCT04543877
Recruiting
The purpose of this study is to determine if adding dietary fiber, such as inulin, to a diet that does not have enough fiber would raise the levels of potentially beneficial bacteria, such as Bifidobacterium, in the gut. There is evidence to suggest that these microbes can affect gut health and immune response, including to vaccines. The investigators will examine how inulin in the diet (compared to the maltodextrin control) (1) causes changes in the composition and function of the gut microbes,... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
06/04/2024
Locations: USDA, ARS, Western Human Nutrition Research Center, Davis, California
Conditions: Inflammation, Vaccine, Intestinal Permeability, Typhoid Fever
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Impact of NMES and HPRO on Recovery After SAH- Pilot Study
NCT03201094
Recruiting
The study purpose is to investigate the hypothesis that in adults with SAH, early neuromuscular electrical stimulation (NMES) and high protein supplementation (HPRO) will improve muscle mass, metabolic and inflammatory biomarker profiles, compared to SAH controls receiving standard of care interventions for nutrition and mobilization. The investigators will accomplish this by studying the effects of a high protein (HPRO) nutritional treatment as well as NMES intervention have upon muscle wasting... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/30/2024
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Subarachnoid Hemorrhage, Muscle Atrophy, Inflammation, Nutritional and Metabolic Disease
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Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury
NCT04810858
Recruiting
This study applies a hypothesis-driven approach to examine the effects of chronic marijuana use on HIV-associated inflammation and its subsequent impacts on central nervous system function, with the goal of identifying the mechanisms through which cannabinoids modulate neurological disorders and other comorbidities in persons with HIV.
Gender:
All
Ages:
Between 25 years and 59 years
Trial Updated:
05/29/2024
Locations: Biotech Place, Winston-Salem, North Carolina
Conditions: Cannabis, HIV, Inflammation, Cognition, Neuroimaging
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Plant-based Diet for Kidney Transplant Recipients
NCT06186843
Recruiting
The goal of this clinical trial is to evaluate cardiometabolic and inflammatory parameters in kidney transplant recipients after transitioning to a plant-based diet (PBD). The main aims of the study are as follows: To test the feasibility of transiting renal allograft recipients who are > 3 months post-transplant to a PBD To study the effect of a PBD on cardiometabolic parameters in kidney transplant recipients To assess the effect of a PBD on peripheral blood Th17/Treg ratio and systemic infla... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/15/2024
Locations: Transplant Institute, Washington, District of Columbia
Conditions: Kidney Disease, Chronic, Transplant Complication, Hypertension, Diabetes Mellitus, Metabolic Syndrome, Inflammation, Kidney Transplant Failure, Dietary Habits
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Diagnosis and Management of Inflammatory and Infectious Diseases
NCT00557726
Recruiting
This protocol is being established to cover the evaluation of patients with inflammatory and/or infectious diseases which are not covered under previously existing protocols. The purpose of such a protocol is that frequently patients are referred to us with either diagnosed or undiagnosed illnesses which would be of interest to our teaching program or which would serve as a source of patients to subsequently be entered into established, ongoing protocol studies. Such patients will be admitted to... Read More
Gender:
All
Ages:
Between 3 years and 100 years
Trial Updated:
05/14/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Infection, Inflammation
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Natural History of the Human Biological Response to Environmental Exposure and Injury
NCT04888923
Recruiting
Background: Environmental exposures like pollution, diet, and stress can help cause human diseases, or make them worse. Researchers want to better understand how injury and inflammation are caused by these exposures. They want to collect biological and environmental samples and other data. They may use the samples to measure a range of factors, like hormones, toxins, and chemicals. This will help them improve their studies. Objective: To identify and understand how environmental exposures con... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: NIEHS Clinical Research Unit (CRU), Research Triangle Park, North Carolina
Conditions: Inflammation, Normal Controls, Metabolic Disease
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Passive Stretching in Peripheral Arterial Disease Patients
NCT06420752
Recruiting
Peripheral artery disease (PAD) leads to higher mortality rates and strains healthcare systems due to increased costs. It causes leg pain during walking due to reduced blood flow. Nitric oxide (NO) deficiency contributes to vascular issues in PAD, with few effective treatments available. Passive calf muscle stretching boosts NO levels, vascular health, and walking ability in PAD patients. However, the inflammatory processes underlying these improvements are unclear. This study aims to track infl... Read More
Gender:
All
Ages:
Between 40 years and 90 years
Trial Updated:
05/14/2024
Locations: University of Wisconsin La Crosse, La Crosse, Wisconsin
Conditions: Peripheral Arterial Disease, Walking, Difficulty, Inflammation
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