There are currently 56 active clinical trials seeking participants for Inflammation research studies. The states with the highest number of trials for Autism participants are California, Texas, Florida and New York.
Zinc Effect on Inflammation and Cardiovascular Risk in HIV
NCT05085834
Recruiting
To study the effect of short-term zinc supplementation on improving inflammation, metabolic, and cardiovascular risk among HIV infected patients on stable anti-retroviral therapy
Gender:
All
Ages:
18 years and above
Trial Updated:
06/28/2023
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Inflammation, Cardiovascular Diseases, Zinc Deficiency
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Diagnosis and Management of Inflammatory and Infectious Diseases
NCT00557726
Recruiting
This protocol is being established to cover the evaluation of patients with inflammatory and/or infectious diseases which are not covered under previously existing protocols. The purpose of such a protocol is that frequently patients are referred to us with either diagnosed or undiagnosed illnesses which would be of interest to our teaching program or which would serve as a source of patients to subsequently be entered into established, ongoing protocol studies. Such patients will be admitted to... Read More
Gender:
All
Ages:
Between 3 years and 100 years
Trial Updated:
04/20/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Infection, Inflammation
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Natural History of the Human Biological Response to Environmental Exposure and Injury
NCT04888923
Recruiting
Background: Environmental exposures like pollution, diet, and stress can help cause human diseases, or make them worse. Researchers want to better understand how injury and inflammation are caused by these exposures. They want to collect biological and environmental samples and other data. They may use the samples to measure a range of factors, like hormones, toxins, and chemicals. This will help them improve their studies. Objective: To identify and understand how environmental exposures con... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/18/2024
Locations: NIEHS Clinical Research Unit (CRU), Research Triangle Park, North Carolina
Conditions: Inflammation, Normal Controls, Metabolic Disease
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Safety, Tolerability, and Distribution of Laquinimod Eye Drops : The LION Study
NCT06161415
Recruiting
The LION Study is a prospective, single-center phase 1 clinical trial to evaluate the safety, tolerability, and distribution of Laquinimod administered as topical eye drops for two weeks in human participants.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: Spencer Center for Vision Research at the Byers Eye Institute, Palo Alto, California
Conditions: Uveitis, Inflammation
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Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women
NCT05552053
Recruiting
Perinatal Mood and Anxiety Disorders (PMADs) encompass a range of mental health disorders that occur during pregnancy and up to one year postpartum. Approximately 13% of women experience PMADs. This rate doubles for those with adverse perinatal outcomes (APO) and triples in Black women. Recent research points to racism as one significant source of these health disparities. Cultural adaptations to improve communication with providers decrease rates of depression in minority patients as well as im... Read More
Gender:
Female
Ages:
Between 18 years and 65 years
Trial Updated:
04/12/2024
Locations: Cedars Sinai, Los Angeles, California
Conditions: Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk, Depression, Depression, Postpartum, Perinatal Depression, Anxiety, Anxiety in Pregnancy, Stress, Psychological, Racism, Discrimination, Racial, Inflammation
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Improving Physical Function in Older Adults Using an Anti-inflammation Drug: The RIGHT Study
NCT05727384
Recruiting
The goal of this clinical trial is to learn about the effects of inflammation-lowering therapy on mobility and disability in older adults. The main questions it aims to answer are: Will therapy improve walking speed/pace? Will therapy improve levels of blood inflammation markers and other indicators of physical, cognitive and immune function? Participants will be asked to receive injections of drug or placebo every 4 weeks for 24 weeks. They will also be asked to undergo testing that assesses... Read More
Gender:
All
Ages:
70 years and above
Trial Updated:
04/11/2024
Locations: University of Pittsburgh, Health Studies Research Center, Pittsburgh, Pennsylvania
Conditions: Inflammation, Frailty
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Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
NCT05277558
Recruiting
Investigators propose to study youth across the spectrum of body mass index (BMI) and dysglycemia. This approach will allow investigators to disentangle the relationship of key features of type 2 diabetes (T2D) risk (e.g. obesity) with intermediary physiologic changes (e.g. insulin resistance, inflammation, β-cell dysfunction and dysglycemia) that pose a risk for the brain. Investigators will determine which of these factors are most associated with differences in brain structure and function am... Read More
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
04/10/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri +1 locations
Conditions: Type2 Diabetes, Type 2 Diabetes Mellitus in Obese, Dysglycemia, Microvascular Complications, Brain Structure, Obesity, Childhood, Diabetes in Adolescence, Inflammation, Insulin Resistance, Overweight, Childhood, Cognitive Decline
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Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation
NCT06130059
Recruiting
The purpose of this research study is to determine the effectiveness of low dose colchicine (LoDoCo) on measures of exercise capacity, physical function, frailty, and quality of life, among patients with heart failure with chronic stable preserved ejection fraction (HFpEF) and systemic inflammation. The use of LoDoCo in this study is considered investigational as it has not been approved by the Food and Drug Administration (FDA) for the treatment of exercise capacity in patients with HFpEF. Par... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
04/09/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Heart Failure, Inflammation
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Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity
NCT05017571
Recruiting
Background: About 40 percent of adults and 20 percent of adolescents in the U.S. have a body mass index over 30 kg/m2. Being overweight may lead to a state of low-level inflammation. This may cause health problems. Researchers want to see if an anti-inflammatory medicine can help. Objective: To learn if colchicine can improve metabolism in people who have high body weight, increased inflammation, and high insulin in the blood but who have not yet developed high blood sugar. Eligibility: Peo... Read More
Gender:
All
Ages:
Between 12 years and 100 years
Trial Updated:
04/04/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Obesity, Insulin Resistance, Inflammation
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ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation
NCT05021835
Recruiting
This study is conducted to see if ziltivekimab reduces the risk of having cardiovascular events (for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation. Participants will either get ziltivekimab (active medicine) or placebo (a dummy medicine which has no effect on the body). This is known as the study medicine. Which treatment participants get is decided by chance. Participants chance of getting ziltivekimab or placebo is the same. Z... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/01/2024
Locations: Uni of Alabama at Birmingham, Birmingham, Alabama +983 locations
Conditions: Cardiovascular Risk, Chronic Kidney Disease, Inflammation
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Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)
NCT05136703
Recruiting
The purpose of this randomized controlled trial is to understand how a cognitive-behavioral treatment (a form of psychological treatment) for depression changes the gut microbiome (micro-organisms that regulate the health of the gut), immune system, and the brain functioning in people living with HIV.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/29/2024
Locations: University of Miami, Miami, Florida
Conditions: Depression, HIV-1-infection, Inflammation
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Regulation of Inflammatory Genes in Psoriasis
NCT03125655
Recruiting
Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.
Gender:
All
Ages:
Between 19 years and 99 years
Trial Updated:
03/26/2024
Locations: The Kirklin Clinic, Birmingham, Alabama
Conditions: Psoriasis, Inflammation
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