There are currently 318 active clinical trials seeking participants for Obesity research studies. The states with the highest number of trials for Obesity participants are California, Texas, Florida and North Carolina.
Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues
Recruiting
This study is for people who have multiple sclerosis, acute leukemia (in remission), or long-COVID and a Body Mass Index over 27 and may struggle with cognitive issues such as remembering information, concentrating, or making decisions that affect everyday life. By doing this study, researchers hope to learn how liraglutide (Saxenda®), a weight loss drug, affects levels of a certain disease marker in the body called Brain Derived Neurotrophic Factor (BDNF). Participation in this research will l... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
07/29/2024
Locations: University of Chicago Medicine Comprehensive Cancer Center, Chicago, Illinois
Conditions: Multiple Sclerosis, Long COVID, Long Covid19, Obese, Obesity, Obesity, Morbid, Acute Leukemia in Remission
Probiotic Intervention Study
Recruiting
The current standard of care for obesity is the optimal management of comorbid conditions such as diabetes and hyperlipidemia, and counseling on diet, weight loss, or increased physical activity programs. However, lifestyle, diet, and behavioral interventions may provide between 7-10% reduction in initial weight and even fewer with long-term weight loss. In severely obese patients (BMI\>40 or BMI\>35 with comorbidities), bariatric surgery is also a potential treatment, but there is a high barrie... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
07/23/2024
Locations: University of California, Los Angeles, California
Conditions: Obesity, Food Addiction
Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy
Recruiting
This will be a prospective, obesity-registry based, single-blind randomized controlled trial with a 1:1 allocation ratio. Specific inclusion criteria are all patients eligible to undergo a Laparoscopic sleeve gastrectomy (LSG) based on the current National Institute of Health (NIH) patient selection guidelines. Patients should be able to give consent, be deemed medically-cleared to undergo elective surgery, and tolerate general anesthesia. All enrollments and surgeries in this study will take pl... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/22/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Post Operative Pain, Laparoscopic Sleeve Gastrectomy, Robotic Sleeve Gastrectomy, Obesity, Bariatric Surgery Candidate, Quality of Life
RESET System Pivotal Trial (Rev F)
Recruiting
A Randomized, Multi-Center, Pivotal Efficacy and Safety Study Evaluating the RESET System for Glycemic Improvement in Patients with Inadequately Controlled Type 2 Diabetes and Obesity, the STEP-1 Study. A multi-center, double-blinded, randomized, sham-controlled trial to evaluate the safety and effectiveness of the RESET System plus moderate intensity lifestyle and dietary counseling compliant with 2024 ADA Standard of Care as compared to a sham control receiving moderate intensity lifestyle an... Read More
Gender:
ALL
Ages:
Between 22 years and 65 years
Trial Updated:
07/16/2024
Locations: MedStar Health Research Institute, Washington, District of Columbia +6 locations
Conditions: Diabetes type2, Obesity
The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults
Recruiting
This clinical trial aims to learn about the alterations in insulin resistance and metabolic flexibility following a transition to an obesogenic lifestyle in fit young men and women. The main questions it aims to answer are: 1. Does adding excess carbohydrates when transitioning to a sedentary lifestyle promote insulin resistance and impaired 24hr glucose regulation in healthy men and women? 2. Does adding excess carbohydrates when transitioning to a sedentary lifestyle lower the body's ability... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
07/16/2024
Locations: University of New Hampshire Cardiometabolic Research Laboratory, Durham, New Hampshire
Conditions: Insulin Resistance, Impaired Glucose Tolerance, Obesity, Metabolic Disturbance
Small Extracellular Vesicles and Insulin Action
Recruiting
The goals of this research study are to: 1) understand why some people with obesity are protected from developing conditions such as type 2 diabetes and cardiovascular disease while others are more likely to develop obesity-related conditions; 2) assess the effect of small extracellular vesicles (sEVs also called exosomes), obtained from human participants, on metabolic function in cultured cells and in mice.
Gender:
ALL
Ages:
Between 25 years and 55 years
Trial Updated:
07/16/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Obesity, Insulin Resistance, Metabolically Healthy Obesity, Obesity, Metabolically Benign
Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia
Recruiting
To assess the feasibility of an expedited referral process for the obese endometrial cancer or EIN patient from her gynecologic oncologist to the Brigham Center for Metabolic and Bariatric Surgery (CMBS) in order to undergo concurrent weight loss surgery and hysterectomy within 8 weeks of first appointment with a gynecologic oncologist (or 12 weeks for EIN patients).
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/15/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts +1 locations
Conditions: Endometrial Carcinoma, Obesity, EIN, Endometrial Intraepithelial Neoplasia, Endometrial Cancer Stage I
Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors
Recruiting
Hypertension and obesity are both major risk factors for cardiovascular disease (CVD), a leading cause of death for Black women in the United States. The investigators propose examining the feasibility and acceptability of the 12-week RN-CHeFRx (Real Nourishment and Cooking Healthy Food is Rx) intervention - grocery delivery, cooking classes, and nutrition education - for Black women with hypertension and obesity to improve nutritious eating habits and blood pressure control.
Gender:
FEMALE
Ages:
Between 18 years and 99 years
Trial Updated:
07/10/2024
Locations: University of Illinois Chicago, Chicago, Illinois
Conditions: Hypertension, Obesity, Nutrition, Healthy
Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial
Recruiting
This is a single site, single-blinded parallel randomized control trial that investigates a multi-level intervention to improve postpartum blood pressure in women with hypertensive disorder pregnancy. The investigators will recruit women diagnosed with a hypertensive disorder of pregnancy, identified between 3rd trimester and 2 weeks post-delivery. The investigators will randomize participants to receive usual care home blood pressure monitoring for 6 weeks versus an intervention of usual care +... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: Magee Women's Hospital of UPMC, Pittsburgh, Pennsylvania
Conditions: Preeclampsia, Hypertensive Disorder of Pregnancy, Toxemia, Pregnancy Complications, Hypertension, Pregnancy-Induced, Hypertension, Obesity, Overweight, Nutrition Disorders, Vascular Diseases, Cardiovascular Diseases, Pre-Eclampsia, Eclampsia, Gestational Hypertension
Family Functioning in Obesity Treatment for Mexican Americans
Recruiting
Mexican American families share similar elevated risks for obesity and obesity-related conditions, such as type 2 diabetes. Because negative family interactions and relationships (e.g., poor communication, high conflict, low emotional closeness) are associated with obesity treatment outcomes, this study tests a behavioral weight management intervention that provides relationship skills counseling to mothers and adult daughters. The goal is to improve family interaction patterns to buffer challen... Read More
Gender:
FEMALE
Ages:
Between 18 years and 65 years
Trial Updated:
07/01/2024
Locations: University of California San Diego, La Jolla, California +1 locations
Conditions: Obesity
Research Framework Exploring Sleep Health
Recruiting
This is a digital health study in which participants are recruited to collect sleep and activity data from digital activity trackers. We are also collecting survey/questionnaire data on baseline health and sleep characteristics as well as bi-weekly assessments of sleep quality and mood. Overall, we aim to examine how sleep relates to physical and mental health in a large population of activity tracker users.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/27/2024
Locations: Scripps Research Institute, La Jolla, California
Conditions: Sleep, Sleep Apnea, Obesity, Mood
Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility
Recruiting
SWIFT-CORE-101 is a single site survey study designed to assess potential participants' eligibility to screen for industry-sponsored clinical trials. A physician will oversee the informed consent process, after which participants will be surveyed on demographics, medical history, comorbidities, and current symptoms. Site staff may collect vital signs, urine drug screens, blood draws, and urine pregnancy tests. A doctor will review medical history with the participant to determine study suitabili... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/10/2024
Locations: Brooklyn Clinical Research, Brooklyn, New York
Conditions: Cardiovascular Diseases, Obesity, PreDiabetes, Diabetes Type 2, Metabolic Syndrome