There are currently 347 active clinical trials seeking participants for Obesity research studies. The states with the highest number of trials for Autism participants are California, Texas, Florida and New York.
Inspiratory Muscle Training in Obese Breast Cancer Survivors
Recruiting
The investigators propose a randomized controlled trial to determine the effectiveness of inspiratory muscle training in improving exercise tolerance among stage 0-III obese breast cancer survivors.
Gender:
Female
Ages:
18 years and above
Trial Updated:
11/14/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Cancer Survivors, Obesity, Breast Cancer
Remote Assessment of Cognition, Insulin Resistance and Omega-3 Fatty Acid Biomarkers in Breast Cancer Survivors
Recruiting
Majority of breast cancer survivors are overweight or obese at time of diagnosis, putting them at increased risk for insulin resistance and Type 2 Diabetes Mellitus (T2DM). Women with insulin resistance at time of breast cancer diagnosis often have larger tumors, later stages of cancer and worse prognosis. Additionally, chemotherapy often leads to increases in insulin resistance and cognitive impairment. Many cancer survivors experience memory and brain function decline following chemotherapy th... Read More
Gender:
Female
Ages:
Between 45 years and 75 years
Trial Updated:
10/25/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Breast Cancer, Obesity
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Recruiting
Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having the shortest life-expectancy of any non-indigenous race/sex group. Unfortunately, a paucity of literature exists on interventions aimed at improving CVH among Black men. The team of clinician scientist... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
09/19/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Cardiometabolic Syndrome, Physical Inactivity, Hypertension, Type 2 Diabetes, PreDiabetes, Obesity, Cardiovascular Diseases, Smoking, Sleep, Hyperlipidemias, Diet, Healthy, Blood Pressure
Stomach Intestinal Pylorus-Sparing Bariatric Surgery
Recruiting
This study will evaluate the safety and efficacy of Stomach Intestinal Pylorus Sparing (SIPS) as a primary bariatric surgery. In addition, we will evaluate the safety and efficacy of SIPS performed as a revisional surgery following sleeve gastrectomy (SG) in which adequate weight loss was not achieved.
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
10/15/2021
Locations: The Ohio State University Wexner Medical Center, Columbus, Ohio
Conditions: Obesity
A Novel Obesity Prevention Program for High-Risk Infants in Primary Care
Recruiting
The goal of this clinical trial is to test a responsive parenting obesity prevention program with infants and caregivers of color (e.g., non-White; Hispanic/Latinx) and/or who are economically marginalized (i.e., publicly insured), delivered via Integrated Behavioral Health (IBH) in pediatric primary care. The main questions it aims to answer are: 1) Is the obesity prevention intervention delivered via IBH in pediatric primary care feasible and acceptable to families of color and/or families wh... Read More
Gender:
All
Ages:
1 day and above
Trial Updated:
03/26/2024
Locations: Hopple Street Neighborhood Health Center, Cincinnati, Ohio
Conditions: Obesity, Obesity, Childhood, Weight Gain, Weight Gain Trajectory
Comparing Reduction With ESD- Versus APC-TORe
Recruiting
The goal of this clinical trial is to compare two variations of the same procedure used to assist with weight loss in patients who have a history of Roux-en-Y gastric bypass who have experienced weight regain. The procedure being studied is called the Transoral Outlet Reduction (TORe), and the trial will compare two different ways to complete the TORe procedure. The main question[s] it aims to answer are: Which variation of the TORe procedure results in more weight loss? Which variation of the... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/03/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Obesity, Roux-en-y Anastomosis Site, Weight Gain
Non-endoscopic Esophageal Sampling to Detect Barrett's Esophagus and Esophageal Cancer in Veterans
Recruiting
This study seeks to incorporate non-endoscopic detection method (Esocheck/Esoguard) in primary care practice and test whether this screening modality increases the positive predictive value of upper endoscopy and increases the detection of Barrett's esophagus and esophageal cancer.
Gender:
All
Ages:
Between 40 years and 85 years
Trial Updated:
12/14/2022
Locations: Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio
Conditions: Barrett Esophagus, GERD, Obesity, Esophageal Cancer
Diabetes and Heart Disease Risk in Blacks
Recruiting
It is unknown if obesity contributes to the development of heart disease in African American men and women. This study was created to determine whether there is a relationship between sex and body size and the incidence of heart disease in African American men and women. Researchers will attempt to associate obesity with the presence of heart disease risk factors. Risk factors that will be studied include; total body fat, body fat distribution, fat content of the blood (triglyceride concentrati... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/02/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Diabetes, Obesity, Hypertension, Cardiovascular Diseases
Mechanisms Underlying Individual Variations of Taste and Smell in Obesity
Recruiting
Background: Changes to the sense of taste or smell can change eating behavior. This may contribute to obesity. Researchers want to see how taste and smell perceptions that affect food choices may differ between people with obesity and without obesity. Objective: To understand the role that senses of taste and smell play in food intake. Eligibility: Adults ages 18-65 with obesity and without obesity Design: Participants will be screened with a medical history and physical exam. They will h... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/02/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Obesity
A Research Study to Look Into How Semaglutide, Together With a Lower Dose of Insulin Glargine, Compares to a Higher Dose of Insulin Glargine Alone in People With Type 2 Diabetes (SUSTAIN OPTIMIZE)
Recruiting
This study compares semaglutide, together with a lower dose of insulin glargine, to a higher dose of insulin glargine in participants with type 2 diabetes. The study looks at how well the study medicines control blood glucose levels. Participants will either get semaglutide together with a lower dose of insulin glargine or a higher dose of insulin glargine. The study will last for about 47 weeks (approximately 11 months). Participants will have 9 clinic visits, 15 phone/video calls and 1 home vi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/02/2024
Locations: Lenzmeier Fam Med CCT Research, Glendale, Arizona +154 locations
Conditions: Diabetes Mellitus, Type 2, Obesity
Energy Expenditure Responses to Different Temperatures
Recruiting
Background: - The way that the body burns calories is known as energy expenditure. Some studies show that when we are cold, we burn more calories to keep our bodies warm. Brown fat is a special kind of fat that can use energy to keep the body warm. Small animals and infants have been known to have brown fat for many years. Recently, it has been suggested that adult humans also have brown fat. If brown fat becomes active (burns calories) in adult humans when exposed to cold, then these people wo... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/02/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Obesity, Normal Physiology
Angiotensin 1-7 in Obesity Hypertension
Recruiting
The purpose of this study is to find out if the investigational drug angiotensin-(1-7) improves cardiovascular health in patients with obesity and high blood pressure.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/02/2024
Locations: Penn State College of Medicine, Hershey, Pennsylvania
Conditions: Obesity, Hypertension