There are currently 347 active clinical trials seeking participants for Obesity research studies. The states with the highest number of trials for Autism participants are California, Texas, Florida and New York.
Inspiratory Muscle Training in Obese Breast Cancer Survivors
Recruiting
The investigators propose a randomized controlled trial to determine the effectiveness of inspiratory muscle training in improving exercise tolerance among stage 0-III obese breast cancer survivors.
Gender:
Female
Ages:
18 years and above
Trial Updated:
11/14/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Cancer Survivors, Obesity, Breast Cancer
Remote Assessment of Cognition, Insulin Resistance and Omega-3 Fatty Acid Biomarkers in Breast Cancer Survivors
Recruiting
Majority of breast cancer survivors are overweight or obese at time of diagnosis, putting them at increased risk for insulin resistance and Type 2 Diabetes Mellitus (T2DM). Women with insulin resistance at time of breast cancer diagnosis often have larger tumors, later stages of cancer and worse prognosis. Additionally, chemotherapy often leads to increases in insulin resistance and cognitive impairment. Many cancer survivors experience memory and brain function decline following chemotherapy th... Read More
Gender:
Female
Ages:
Between 45 years and 75 years
Trial Updated:
10/25/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Breast Cancer, Obesity
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Recruiting
Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having the shortest life-expectancy of any non-indigenous race/sex group. Unfortunately, a paucity of literature exists on interventions aimed at improving CVH among Black men. The team of clinician scientist... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
09/19/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Cardiometabolic Syndrome, Physical Inactivity, Hypertension, Type 2 Diabetes, PreDiabetes, Obesity, Cardiovascular Diseases, Smoking, Sleep, Hyperlipidemias, Diet, Healthy, Blood Pressure
Stomach Intestinal Pylorus-Sparing Bariatric Surgery
Recruiting
This study will evaluate the safety and efficacy of Stomach Intestinal Pylorus Sparing (SIPS) as a primary bariatric surgery. In addition, we will evaluate the safety and efficacy of SIPS performed as a revisional surgery following sleeve gastrectomy (SG) in which adequate weight loss was not achieved.
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
10/15/2021
Locations: The Ohio State University Wexner Medical Center, Columbus, Ohio
Conditions: Obesity
A Novel Obesity Prevention Program for High-Risk Infants in Primary Care
Recruiting
The goal of this clinical trial is to test a responsive parenting obesity prevention program with infants and caregivers of color (e.g., non-White; Hispanic/Latinx) and/or who are economically marginalized (i.e., publicly insured), delivered via Integrated Behavioral Health (IBH) in pediatric primary care. The main questions it aims to answer are: 1) Is the obesity prevention intervention delivered via IBH in pediatric primary care feasible and acceptable to families of color and/or families wh... Read More
Gender:
All
Ages:
1 day and above
Trial Updated:
03/26/2024
Locations: Hopple Street Neighborhood Health Center, Cincinnati, Ohio
Conditions: Obesity, Obesity, Childhood, Weight Gain, Weight Gain Trajectory
Comparing Reduction With ESD- Versus APC-TORe
Recruiting
The goal of this clinical trial is to compare two variations of the same procedure used to assist with weight loss in patients who have a history of Roux-en-Y gastric bypass who have experienced weight regain. The procedure being studied is called the Transoral Outlet Reduction (TORe), and the trial will compare two different ways to complete the TORe procedure. The main question[s] it aims to answer are: Which variation of the TORe procedure results in more weight loss? Which variation of the... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/03/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Obesity, Roux-en-y Anastomosis Site, Weight Gain
Non-endoscopic Esophageal Sampling to Detect Barrett's Esophagus and Esophageal Cancer in Veterans
Recruiting
This study seeks to incorporate non-endoscopic detection method (Esocheck/Esoguard) in primary care practice and test whether this screening modality increases the positive predictive value of upper endoscopy and increases the detection of Barrett's esophagus and esophageal cancer.
Gender:
All
Ages:
Between 40 years and 85 years
Trial Updated:
12/14/2022
Locations: Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio
Conditions: Barrett Esophagus, GERD, Obesity, Esophageal Cancer
MEHMO Natural History and Biomarkers
Recruiting
This observational natural history study will follow individuals with MEHMO (Mental disability, Epileptic seizure, Hypopituitarism/Hypogenitalism, Microcephaly, Obesity) syndrome or an eIF2-pathway related disorder, who have symptoms such as intellectual delay, seizures, abnormal hormone and blood sugar levels, and decreased motor skills. No current treatment for these conditions is available. A major impediment to the testing of potential therapeutic interventions is the lack of well-defined o... Read More
Gender:
All
Ages:
Between 1 week and 100 years
Trial Updated:
04/23/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Intellectual Disability, Epilepsy, Hypogonadisms, Microcephaly, Nervous System Malformations, Obesity
Competency Based Approaches for Community Health 2
Recruiting
One-size-fits-all approaches have failed to demonstrate sustained effects on childhood obesity, especially among low-income minority families, who experience constantly changing barriers to engaging in health behavior. Addressing obesity in these populations requires intervening in early childhood and situating interventions in the context of families and communities. Developing personalized childhood obesity prevention interventions with sustained effectiveness that support families in health b... Read More
Gender:
All
Ages:
4 years and above
Trial Updated:
04/23/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Obesity
The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
Recruiting
Background: Diet-induced thermogenesis (DIT) is the amount of energy one s body uses to eat food, absorb the nutrients from the food, and process those nutrients. Researchers would like to understand more about how changing the balances of protein, fat, carbohydrates, and total calories in the diet can affect DIT. Objective: To learn how different diets can change a person s DIT. Eligibility: Healthy people aged 18 to 60 years who have not intentionally lost weight in the past 6 months. De... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
04/23/2024
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Obesity, Normal Physiology, Healthy Volunteers
Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE)
Recruiting
A randomized, double-blinded, placebo controlled study intended to capture cardiovascular outcomes during real-world use of naltrexone/bupropion (NB).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Accel Research Sites Network, Birmingham, Alabama +93 locations
Conditions: Obesity
The Weight of Cardiovascular Disease
Recruiting
The purpose of this study is to evaluate the impact of a cardiometabolic clinic on percent body weight loss, body mass index (BMI), and visceral adiposity distribution in obese adults with cardiovascular disease (CVD) at 12 months.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Cardiovascular Diseases, Obesity