There are currently 246 active clinical trials seeking participants for Stroke research studies. The states with the highest number of trials for Stroke participants are California, Florida, New York and Ontario.
Post-stroke Pain taVNS
NCT06456385
Recruiting
The purpose of this study is to explore whether a non-invasive form of ear stimulation called transcutaneous auricular vagus nerve stimulation (taVNS) can change the way participants perceive pain. Investigators will recruit up to 20 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/07/2024
Locations: Medical University of South Carolina Institute of Psychiatry, Charleston, South Carolina
Conditions: Stroke, Pain
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Sleep for Stroke Management and Recovery Trial
NCT03812653
Recruiting
The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/07/2024
Locations: University of Alabama Hospital, Birmingham, Alabama +111 locations
Conditions: Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, TIA, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial
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Non-invasive BCI-controlled Assistive Devices
NCT05183152
Recruiting
Injuries affecting the central nervous system may disrupt the cortical pathways to muscles causing loss of motor control. Nevertheless, the brain still exhibits sensorimotor rhythms (SMRs) during movement intents or motor imagery (MI), which is the mental rehearsal of the kinesthetics of a movement without actually performing it. Brain-computer interfaces (BCIs) can decode SMRs to control assistive devices and promote functional recovery. Despite rapid advancements in non-invasive BCI systems ba... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/06/2024
Locations: The University of Texas at Austin, Austin, Texas
Conditions: Motor Disorders, Healthy, Spinal Cord Injuries, Muscular Diseases, Motor Neuron Disease, Stroke, Traumatic Brain Injury, Movement Disorders, Multiple Sclerosis
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Motor and Neurophysiological Changes After Ischemic Conditioning in Individuals With Stroke
NCT05906602
Recruiting
The goal of this clinical trial is to test ischemic conditioning (blood flow restriction) as a neuromodulatory technique to improve gait function in stroke. Neuromodulation is emerging as a promising adjunct strategy to facilitate changes in brain activity and improve motor behavior following a neurological injury such as stroke. The main questions this trial aims to answer are: Can ischemic conditioning produce neuromodulatory changes in the lower limb primary motor cortex? Can ischemic condi... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
06/04/2024
Locations: University of Illinois Chicago, Chicago, Illinois
Conditions: Stroke
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MyHand 2: An Active Hand Orthosis for Stroke Patients
NCT04436042
Recruiting
This study is designed to further develop and test the hardware and software components of the MyHand device based on user feedback and results from our pilot study. The goal is to refine the device so that is more effective and easier for stroke patients to use to increase their hand function.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Stroke, Hemiparesis
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Amulet™ ADVANCE LAA
NCT05997446
Recruiting
This is a prospective, multicenter, observational study intended to characterize real-world outcomes on the commercially available Amulet device in the United States. The study will enroll approximately 1000 subjects at up to 50 US clinical sites. Subjects will be followed through 24 months in accordance with each site's standard care practices.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Arizona Arrhythmia Research, Phoenix, Arizona +26 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
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Blood Flow Regulation and Neuromuscular Function Post-Stroke
NCT06027294
Recruiting
The muscles of stroke survivors can fatigue faster compared to muscles in people who have not had a stroke, which can limit how long a person with stroke can perform tasks such as walking. This study will examine how blood flow is regulated to the exercising leg muscle post-stroke, because if the muscle does not receive enough blood flow it will become fatigued. Finally, the investigators will use a safe and simple non-invasive intervention called ischemic conditioning, which has known effects t... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/30/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin +1 locations
Conditions: Stroke
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Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
NCT06347484
Recruiting
The CONNECT: "Developing a learning COmmunity to increase eNgagemeNt and Enrollment in cardiovascular Clinical Trials" is comprehensive, participant-centered learning community that provides tailored education on cardiovascular (CV) health and research participation; connects community members to CV-related research; and disseminates CV-related study findings. The overreaching goal of CONNECT is to improve participation of underrepresented communities in CV research, including as women, Black ad... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/29/2024
Locations: Johns Hopkins University School of Nursing, Baltimore, Maryland
Conditions: Cardiovascular Diseases, Hypertension, Diabetes Type 2, Stroke, Recruitment, Overweight and Obesity, Hyperlipidemias
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Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis
NCT05047172
Recruiting
The primary goal of the trial is to determine if the experimental arms (rivaroxaban or ticagrelor or both) are superior to the clopidogrel arm for lowering the 1-year rate of ischemic stroke, intracerebral hemorrhage, or vascular death.
Gender:
All
Ages:
30 years and above
Trial Updated:
05/28/2024
Locations: University of Alabama Hospital, Birmingham, Alabama +113 locations
Conditions: Intracranial Arteriosclerosis, Stroke
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Use of Sensory Substitution to Improve Arm Control After Stroke
NCT03298243
Recruiting
Supplementing or augmenting sensory information to those who have lost proprioception after stroke could help improve functional control of the arm. Thirty subjects will be recruited to a single site to evaluate the ability of supplemental kinesthetic feedback (a form of vibrotactile stimulation) to improve motor function. Participants will be tested in performing reaching movements as well as more functional tasks such as simulated drinking from a glass
Gender:
All
Ages:
21 years and above
Trial Updated:
05/28/2024
Locations: Marquette University, Milwaukee, Wisconsin
Conditions: Stroke, Proprioceptive Disorders
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Stroke Rehabilitation Using Brain-Computer Interface (BCI) Technology
NCT04141774
Recruiting
The purpose of this research is to determine if functional muscle stimulation, directed by electroencephalogram (EEG) output, can increase the extent of stroke recovery on behavioral measures and induce brain plasticity as measured by functional magnetic resonance imaging (fMRI). Participants will include stroke patients with upper-limb hemiparesis and can expect to be on study for approximately 4 months.
Gender:
All
Ages:
Between 50 years and 85 years
Trial Updated:
05/28/2024
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Stroke
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Transferring Speed of Processing Gains to Everyday Cognitive Tasks After Stroke
NCT05162781
Recruiting
This study will compare two approaches to cognitive rehabilitation in adults with stroke with persistent, mild to moderate, cognitive impairment. Both approaches will feature a web-based computer "game" that trains cognitive processing speed, i.e., how quickly individuals process information that they receive through their senses. This training is termed Speed of Processing Training (SOPT). One approach will add (A) in-lab training on everyday activities with important cognitive components and (... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
05/23/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Stroke, Cognitive Dysfunction
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