There are currently 247 active clinical trials seeking participants for Stroke research studies. The states with the highest number of trials for Stroke participants are California, Florida, New York and Ontario.
Music Listening for Mental Health Recovery After Stroke
NCT07127159
Recruiting
This study aims to explore whether listening to music intentionally can support the mental health of people recovering from a stroke. The question the investigators aim to answer is: Can intentional music listening improve emotional well-being in stroke survivors? And if so, what kinds of changes might music listening induce in mental health, thinking and memory (cognition), and brain activity? Participants will be randomly assigned to listen to either music or an audiobook for one hour each da... Read More
Gender:
ALL
Ages:
Between 50 years and 90 years
Trial Updated:
08/11/2025
Locations: New York University, New York, New York
Conditions: Stroke
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tVNS Responsiveness Testing With Pupil Size
NCT06335199
Recruiting
The goal of this study is to learn about the acute pupil response to transcutaneous vagus nerve stimulation (tVNS) in stroke survivors and healthy adults. The main question it aims to answer is whether pupil size response is greater with bilateral tVNS compared to unilateral tVNS. Participants will receive tVNS and sham at the outer ear unilaterally and bilaterally in resting condition. The pupil size of the participants will be recorded during tVNS.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
08/08/2025
Locations: Human Neuromuscular Physiology Lab, Atlanta, Georgia
Conditions: Stroke
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Pilot/Pivotal Study of DBS+Rehab After Stroke
NCT05701280
Recruiting
The RESTORE Stroke Study will evaluate the safety and effectiveness of DBS+Rehab for treating arm weakness and reduced function after a stroke.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
08/04/2025
Locations: Barrow Neurological Institute (BNI), Phoenix, Arizona +7 locations
Conditions: Stroke, Upper Extremity Paresis
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tACS to Enhance Language Abilities
NCT06092814
Recruiting
The goal of this study is to see if transcranial alternating current stimulation (tACS) can be used to enhance language abilities in people with post-stroke aphasia. Participants will receive real and sham tACS in conjunction with various language tests. Researchers will compare the post-stroke aphasia group with aged matched controls to see if brain response to tACS differs between groups.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
08/04/2025
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Stroke, Aphasia, Acquired, Aphasia
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Strategy Training for Individuals With Unilateral Neglect
NCT06400147
Recruiting
It is common for individuals after stroke to have a cognitive perceptual impairment called unilateral spatial neglect (neglect). Individuals with neglect have difficulty paying attention to one side of their body or one side of the environment and therefore experience difficulty performing daily activities. There are a lack of effective treatments for neglect and new interventions are needed to help reduce disability for these individuals. Metacognitive strategy training (strategy training) is a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/04/2025
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Stroke, Neglect, Hemispatial
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Sleep for Stroke Management and Recovery Trial
NCT03812653
Recruiting
The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/01/2025
Locations: University of Alabama Hospital, Birmingham, Alabama +115 locations
Conditions: Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial
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Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With Stroke
NCT07113041
Recruiting
Our proposed study, "NEUROBALANCE Stroke,"; aims to evaluate the effectiveness of a combined intervention involving robotic balance training and noninvasive brain stimulation in improving balance function and postural control in individuals with chronic stroke. The study will recruit 45 participants who have had a stroke at least 6 months before enrolment and experience persistent balance and gait deficits. Participants will be randomized into three groups: (1) robotic balance training with acti... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/01/2025
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Stroke, Stroke (CVA) or Transient Ischemic Attack, Stroke Ischemic, Stroke Gait Rehabilitation, Balance Deficits
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Virtual Reality-Integrated Propulsion Feedback for Stroke Rehab
NCT07087743
Recruiting
This study evaluates a novel Virtual Reality (VR)-integrated visual feedback system designed to enhance limb propulsion during robot-assisted gait rehabilitation in individuals post-stroke. In collaboration with CUREXO, a rehabilitation robotics company, the system is embedded within the Morning Walk® end-effector robot and provides real-time visual feedback to facilitate symmetrical use of the paretic and non-paretic limbs. The goal is to address gait asymmetry commonly observed in hemiparetic... Read More
Gender:
ALL
Ages:
20 years and above
Trial Updated:
07/31/2025
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: Stroke, Robot Assisted Gait Training, Virtual Reality
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Optimizing Gait Symmetry After Stroke Using Mechanical Constraints and Sensory Feedback
NCT07087769
Recruiting
This single-session study aims to evaluate a novel gait training protocol that integrates mechanical constraints and sensory feedback to enhance paretic leg propulsion in individuals post-stroke. The study will include 15 individuals who have experienced a stroke and 15 healthy adults, each aged 20 years or older. Participants will walk on both tied-belt and split-belt treadmills under various training conditions, including backward-directed resistance (applied at the pelvis, ankle, or both) and... Read More
Gender:
ALL
Ages:
20 years and above
Trial Updated:
07/31/2025
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: Stroke, Split-belt Treadmill, Resistance Exercise, Feedback, Gait Training
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To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors
NCT06247553
Recruiting
The goal of this clinical trial is to test a gait (walking) training program in non-ambulatory (unable to walk) chronic stroke survivors. The main question it aims to answer is: • Will gait training improve the cardiovascular system in non-ambulatory chronic stroke survivors better than a sitting leg cycling exercise? Participants will walk on a treadmill with a partial body-weight support system and the gait training device. Researchers will compare with a leg-cycling exercise to see if there... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/30/2025
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Stroke, Walking, Difficulty, Cardiovascular Injury
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Visual Plasticity Following Brain Lesions
NCT07105358
Recruiting
The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/29/2025
Locations: Georgetown University Medical Center, Washington, District of Columbia
Conditions: Visual Field Defect, Stroke, Hemianopia, Quadrantanopia, Cortical Blindness, Brain Tumor, Traumatic Brain Injury, Visual Field Defect, Peripheral
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Transferring Speed of Processing Gains to Everyday Cognitive Tasks After Stroke
NCT05162781
Recruiting
This study will compare two approaches to cognitive rehabilitation in adults with stroke with persistent, mild to moderate, cognitive impairment. Both approaches will feature a web-based computer "game" that trains cognitive processing speed, i.e., how quickly individuals process information that they receive through their senses. This training is termed Speed of Processing Training (SOPT). One approach will add (A) in-lab training on everyday activities with important cognitive components and (... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
07/27/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Stroke, Cognitive Dysfunction
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