There are currently 815 clinical trials in Washington, District Of Columbia looking for participants to engage in research studies. Trials are conducted at various facilities, including Children's National Medical Center, Medstar Georgetown University Hospital, MedStar Washington Hospital Center and Walter Reed Army Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection
NCT05219110
Recruiting
The objective of this study is to determine if early high volume intravenous fluid administration (hyperhydration) may be effective in mitigating or preventing complications of shiga toxin-producing E. coli (STEC) infection in children and adolescents when compared with traditional approaches (conservative fluid management).
Gender:
ALL
Ages:
Between 9 months and 21 years
Trial Updated:
06/02/2025
Locations: Children's Research Institute, Washington, District of Columbia
Conditions: Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection, Hemolytic-Uremic Syndrome
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Emicizumab in Patients With Acquired Hemophilia A
NCT05345197
Recruiting
This is a phase II multicenter open-label, single-arm prospective study to evaluate the efficacy of prophylactic emicizumab administered on a scheduled basis to prevent bleeds in patients with acquired hemophilia A (AHA).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/02/2025
Locations: Georgetown University, Washington, District of Columbia
Conditions: Acquired Hemophilia A
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Digoxin Medulloblastoma Study
NCT06701812
Recruiting
The purpose of this study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients.
Gender:
ALL
Ages:
Between 12 months and 30 years
Trial Updated:
06/02/2025
Locations: Children's National Medical Center, Washington, District of Columbia
Conditions: Medulloblastoma, Medulloblastoma, Non-WNT/Non-SHH
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Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study)
NCT04947319
Recruiting
This study will evaluate the efficacy, safety, and pharmacokinetics of tirabrutinib monotherapy in patients with relapsed or refractory PCNSL (Part A), and tirabrutinib in combination with one of two different high dose methotrexate based regimens (methotrexate/ temozolomide/rituximab or rituximab/methotrexate/procarbazine/ vincristine) as first line therapy in patients with newly diagnosed, treatment naïve PCNSL (Part B)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/01/2025
Locations: Georgetown University, Lombardi Comprehensive Cancer Center, Washington, District of Columbia
Conditions: Refractory Primary Central Nervous System Lymphoma, Primary CNS Lymphoma
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Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease
NCT06605378
Recruiting
This research study is designed to assess the prevalence of specific antibodies and inflammatory cytokines in adult and pediatric participants with CGD.
Gender:
ALL
Ages:
All
Trial Updated:
05/30/2025
Locations: Home-based telemedicine, Washington, District of Columbia
Conditions: Chronic Granulomatous Disease (CGD)
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Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies
NCT02203903
Recruiting
This Phase I dose-escalation trial is designed to evaluate the safety of administering rapidly -generated tumor multi-antigen associated -specific cytotoxic T lymphocytes, to HSCT recipients with high risk AML and MDS.
Gender:
ALL
Ages:
Between 6 months and 80 years
Trial Updated:
05/29/2025
Locations: Childrens National Medical Center, Washington, District of Columbia
Conditions: Relapsed/Refractory Hematopoietic Malignancies, Acute Myeloid Leukemia and MDS
Register for Updates
Spinal Cord Injury Model Systems (SCIMS) - Education Module
NCT06003686
Recruiting
The purpose of this study is to find out if receiving education regarding increased risks of cardiometabolic disease helps subjects understand these risks and how these risks participants' health.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/29/2025
Locations: MedStar National Rehabilitation Network, Washington, District of Columbia
Conditions: Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
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Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
NCT01297400
Recruiting
To compare MW-III to Silvadene® Cream 1% (Silver Sulfadiazine) with respect to "time to healing" (≥95% re-epithelialization) of a partial thickness target thermal burn.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2025
Locations: MedStar Washington Hospital Center, Washington, District of Columbia
Conditions: Burns
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The CARING Study: Creating and Restoring Health Through Nutrition Guidance
NCT05795439
Recruiting
The CARING study assesses the health benefits of nutrition education for Blue Cross Blue Shield subscribers, as well as potential healthcare cost savings to subscribers and the insurance company.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2025
Locations: Physicians Committee for Responsible Medicine, Washington, District of Columbia
Conditions: Type2diabetes, Type 2 Diabetes Treated With Insulin
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The Effect of a Low-fat Vegan Dietary Intervention on Intracellular Lipid, Insulin Sensitivity, and Glycemic Control in Type 2 Diabetes
NCT06106035
Recruiting
The goal of this 16-week clinical trial is to assess the health benefits of a low-fat vegan diet on insulin sensitivity and glycemic control in type 2 diabetes. Participants will receive at no cost, study-related weekly nutrition education classes and one-on-one consultation with a registered dietitian.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2025
Locations: Physicians Committee for Responsible Medicine, Washington, District of Columbia
Conditions: Diabetes Mellitus, Type 2, Diabetes Mellitus Type 2 in Obese
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A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma
NCT06256588
Recruiting
The goal of this study is to assess the safety and effectiveness of Dostarlimab compared to Placebo in adult participants with HNSCC (Head and Neck Squamous Cell Carcinoma)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2025
Locations: GSK Investigational Site, Washington, District of Columbia
Conditions: Neoplasms, Head and Neck
Register for Updates
STAND - Study of the AGN1 LOEP SV Kit Compared to PMMA in Patients With Vertebral Compression Fractures
NCT04835428
Recruiting
This is a multicenter, single-blinded, randomized controlled clinical trial evaluating the safety and efficacy of the AGN1 LOEP SV Kit for the treatment of painful vertebral compression fragility fractures (VCFs). The objective of this study is to demonstrate non-inferiority of the AGN1 LOEP SV Kit for the treatment of VCFs to standard of care vertebroplasty treatment using bipedicular injection of PMMA bone cement.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
05/27/2025
Locations: GW Medical Faculty Associates, Washington, District of Columbia
Conditions: Vertebral Compression Fracture, Compression Fracture, Vertebral Compression
Register for Updates