There are currently 94 clinical trials in Tallahassee, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Florida State University, Tallahassee Memorial Hospital, Tallahassee Memorial Healthcare and Tallahassee Research Institute. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Listener Training for Improved Intelligibility of People With Parkinson's Disease
NCT06815263
Recruiting
Listener training offers a promising avenue for improving communication for people with dysarthria due to Parkinson's disease by offsetting the intelligibility burden from the patient onto their primary communication partners. Here, we employ a repeated-measures, randomized controlled trial to establish the efficacy of listener training for patients with PD and their primary communication partners. This translational work will establish a new realm of clinical practice in which the intelligibili... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/02/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: Dysarthria, Hypokinetic
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Exercise Training and Fat Metabolism in Postmenopausal Women
NCT05351476
Recruiting
Adipose tissue turnover plays a critical role in body weight maintenance, and obesity is underscored by the dysregulated balance between fat breakdown and synthesis. Although there are clear health-related benefits of physical activity, little is known about how resistance exercise, as opposed to endurance exercise, can reduce the risk of metabolic disorders, particularly in women. The goal of the proposed study is to investigate the effectiveness of resistance training to improve basal and stim... Read More
Gender:
FEMALE
Ages:
Between 50 years and 75 years
Trial Updated:
04/02/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: Postmenopausal Symptoms, Obesity, Prediabetic State
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Effect of Peanut Butter on Gut and Metabolic Health
NCT06916936
Recruiting
The goal of this is parallel arm, randomized clinical trial is to learn and understand the effect of daily smooth peanut butter consumption on gut and metabolic health of children age 6-13. The main objectives are: Primary Objective: To determine the prebiotic effect of daily smooth peanut butter consumption for eight weeks on gut health, including microbiome-metabolome arrays, gut epithelial/barrier function, and gut transit time, in school-aged children. Secondary Objective(s) 1. To determi... Read More
Gender:
ALL
Ages:
Between 6 years and 13 years
Trial Updated:
04/01/2025
Locations: Florida State Univresity - The Gut Biome Lab, Tallahassee, Florida
Conditions: Dysbiosis
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SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
NCT06001827
Recruiting
This is a prospective, randomized, multi-center clinical trial for chronic kidney disease (CKD) patients referred for creation of a new arteriovenous fistula (AVF) in order to assess the safety and effectiveness of SelfWrap, a bioabsorbable perivascular wrap.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: Tallahassee Research Institute, Tallahassee, Florida
Conditions: Chronic Kidney Diseases, End Stage Renal Disease, Arteriovenous Fistula, Hemodialysis Access Failure, ESRD, Vascular Access Complication, Renal Failure, Catheter Complications, Catheter Dysfunction, Renal Insufficiency
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Speech Rehabilitation Based on Mobile Applications
NCT06592183
Recruiting
This study evaluates the efficacy of smartphone-based speech therapy administered at home compared with usual care. Participants will be randomized into the treatment and waitlist control groups with an allocation ratio of 1:1.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: Stroke, Motor Speech Disorder
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Efficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults with Gorlin Syndrome
NCT06050122
Recruiting
The aim of this clinical study is to find out how well Patidegib Gel 2% works in preventing new basal cell carcinomas (BCCs) developing on the face of adults with Gorlin syndrome, and how safe Patidegib Gel 2% is to use. People who take part will apply either Patidegib Gel 2% or a Vehicle Gel (with no active drug substance) to their face twice a day for a year (12 months). The number of new BCCs on the face will be compared between those who used Patidegib Gel 2% or Vehicle Gel after 12 months.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: Dermatology Associates of Tallahassee, Tallahassee, Florida
Conditions: Gorlin Syndrome
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A Neurosensory Account
NCT05895006
Recruiting
The goal of this study is to develop and test a novel pathophysiology of PTSD by integrating sensory cortical (SC) and amygdala-PFC dysfunctions into a tripartite Sensory-Prefrontal-Cortex-Amygdala (SPA) model.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
03/05/2025
Locations: Leon County, Tallahassee, Florida
Conditions: Post Traumatic Stress Disorder
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Central Executive Training and Parent Training for ADHD
NCT05492422
Recruiting
The goal of the current project is to combine two evidence- based treatments for school-aged children with ADHD: Central Executive Training (CET) and Behavioral Parent Training (BPT). CET is a computerized training intervention that improves ADHD symptoms and academic functioning by improving children's working memory abilities. BPT is a therapeutic intervention that improves family functioning and child oppositional-defiant (ODD) symptoms by changing parenting behaviors. Their combined use is e... Read More
Gender:
ALL
Ages:
Between 8 years and 12 years
Trial Updated:
03/05/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: ADHD
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Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression
NCT06132581
Recruiting
Anhedonia, the inability to seek-out and experience pleasure, is a common symptom in depression that predicts treatment-resistance and is sometimes exacerbated by first-line antidepressants. In our previous research, we found that anhedonia decreases goal-directed behavior and its related neural activity. In this study, we will investigate target engagement from five-consecutive days of stimulation for participants that are within a unipolar major depressive episode and also have high symptoms o... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/05/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: Major Depressive Disorder, Anhedonia
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Causal Role of the Aperiodic Signal for Working Memory
NCT06126809
Recruiting
Working memory (WM) is the ability to hold relevant information in mind in the absence of sensory input. The capacity for WM is a foundation for cognitive control and higher cognitive function more broadly. Previous research demonstrated that during the delay period of WM tasks, oscillatory electrical activity in the prefrontal cortex in the theta-frequency band (4-8 Hz) increased in amplitude. However, other groups found that the slope of the aperiodic signal in the brain was positively correla... Read More
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
03/05/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: Executive Dysfunction
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Causal Role of Delta and Theta Oscillations in Hierarchical Cognitive Control
NCT06734377
Recruiting
The purpose of this clinical trial is to evaluate the effect of rhythmic transcranial magnetic stimulation (TMS) delivered at delta (2.2 Hz) or theta (6.5 Hz) frequency on cognitive control. This study aims to explore how targeted stimulation at delta and theta frequencies modulates brain activity to enhance cognitive performance in healthy populations.
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
03/04/2025
Locations: Florida State University Psychology Dept Bldg A411, Tallahassee, Florida
Conditions: Rhythmic Transcranial Magnetic Stimulation (rTMS) Effect on Hierarchical Cognitive Control
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How Seasons Affect Kidney Health in Post-Menopausal Females
NCT06866743
Recruiting
The investigators are assessing how seasonal changes affect kidney function biomarkers in post-menopausal women, an understudied group. While heat stress can reduce kidney function, previous research has not accounted for physical activity, diet, hydration, or sun exposure.
Gender:
FEMALE
Ages:
55 years and above
Trial Updated:
03/04/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: Postmenopausal, Female
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