There are currently 89 clinical trials in Tallahassee, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Florida State University, Tallahassee Memorial Hospital, Tallahassee Memorial HealthCare and Tallahassee Research Institute. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
NCT02071134
Recruiting
The purpose of this registry is to compile characteristics of world-wide outcomes for the use of Boston Scientific's commercially available Vercise DBS System in the treatment of Parkinson's disease. The utilization of Image Guided Programming (IGP), and other commercially available programming features, used as planning tools for the programming of patients with Boston Scientific's Vercise DBS System are also evaluated. Additionally, the utilization of the DBS Illumina 3D feature that may be... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/06/2025
Locations: Tallahassee Neurological Clinic, PA, Tallahassee, Florida
Conditions: Parkinson's Disease
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Causal Role of the Aperiodic Signal for Working Memory
NCT06126809
Recruiting
Working memory (WM) is the ability to hold relevant information in mind in the absence of sensory input. The capacity for WM is a foundation for cognitive control and higher cognitive function more broadly. Previous research demonstrated that during the delay period of WM tasks, oscillatory electrical activity in the prefrontal cortex in the theta-frequency band (4-8 Hz) increased in amplitude. However, other groups found that the slope of the aperiodic signal in the brain was positively correla... Read More
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
03/05/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: Executive Dysfunction
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A Neurosensory Account
NCT05895006
Recruiting
The goal of this study is to develop and test a novel pathophysiology of PTSD by integrating sensory cortical (SC) and amygdala-PFC dysfunctions into a tripartite Sensory-Prefrontal-Cortex-Amygdala (SPA) model.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
03/05/2025
Locations: Leon County, Tallahassee, Florida
Conditions: Post Traumatic Stress Disorder
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Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression
NCT06132581
Recruiting
Anhedonia, the inability to seek-out and experience pleasure, is a common symptom in depression that predicts treatment-resistance and is sometimes exacerbated by first-line antidepressants. In our previous research, we found that anhedonia decreases goal-directed behavior and its related neural activity. In this study, we will investigate target engagement from five-consecutive days of stimulation for participants that are within a unipolar major depressive episode and also have high symptoms o... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/05/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: Major Depressive Disorder, Anhedonia
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Central Executive Training and Parent Training for ADHD
NCT05492422
Recruiting
The goal of the current project is to combine two evidence- based treatments for school-aged children with ADHD: Central Executive Training (CET) and Behavioral Parent Training (BPT). CET is a computerized training intervention that improves ADHD symptoms and academic functioning by improving children's working memory abilities. BPT is a therapeutic intervention that improves family functioning and child oppositional-defiant (ODD) symptoms by changing parenting behaviors. Their combined use is e... Read More
Gender:
ALL
Ages:
Between 8 years and 12 years
Trial Updated:
03/05/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: ADHD
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How Seasons Affect Kidney Health in Post-Menopausal Females
NCT06866743
Recruiting
The investigators are assessing how seasonal changes affect kidney function biomarkers in post-menopausal women, an understudied group. While heat stress can reduce kidney function, previous research has not accounted for physical activity, diet, hydration, or sun exposure.
Gender:
FEMALE
Ages:
55 years and above
Trial Updated:
03/04/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: Postmenopausal, Female
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Breathing & Blood Pressure
NCT05632406
Recruiting
The purpose of this study is to determine the effect of obesity on cardiovascular responses during various breathing maneuvers.
Gender:
ALL
Ages:
Between 20 years and 45 years
Trial Updated:
03/04/2025
Locations: Florida State University, Tallahassee, Florida
Conditions: Healthy, Overweight and Obesity
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Causal Role of Delta and Theta Oscillations in Hierarchical Cognitive Control
NCT06734377
Recruiting
The purpose of this clinical trial is to evaluate the effect of rhythmic transcranial magnetic stimulation (TMS) delivered at delta (2.2 Hz) or theta (6.5 Hz) frequency on cognitive control. This study aims to explore how targeted stimulation at delta and theta frequencies modulates brain activity to enhance cognitive performance in healthy populations.
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
03/04/2025
Locations: Florida State University Psychology Dept Bldg A411, Tallahassee, Florida
Conditions: Rhythmic Transcranial Magnetic Stimulation (rTMS) Effect on Hierarchical Cognitive Control
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Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's
NCT05748613
Recruiting
The goal of this clinical trial is to test the effectiveness of a computerized anxiety sensitivity treatment (CAST) compared to a health education control (HEC) in older adults with mild cognitive impairment (MCI) or mild Alzheimer's Disease and related dementias (ADRD) and their care partners. The main questions it aims to answer are: 1. Efficacy of CAST in reducing anxiety and related symptoms among those with MCI/mild ADRD 2. Efficacy of CAST in reducing care partner burden among care partne... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
03/03/2025
Locations: Anxiety and Behavioral Health Clinic, Tallahassee, Florida
Conditions: Anxiety, Mild Cognitive Impairment, Alzheimer Disease, Dementia
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Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors
NCT05896189
Recruiting
This Phase III trial will examine the efficacy of computerized cognitive training methods on perceived cognitive impairment in breast cancer survivors.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
03/03/2025
Locations: Tallahassee Memorial HealthCare, Tallahassee, Florida
Conditions: Breast Cancer, Cognitive Impairments
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The EMPOWER Trial - the Carillon Mitral Contour System® in Treating Heart Failure with At Least Mild FMR
NCT03142152
Recruiting
The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart failure with functional regurgitation (FMR).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/03/2025
Locations: Tallahassee Research Institute, Tallahassee, Florida
Conditions: Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases
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Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients
NCT05732779
Recruiting
We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR) episodes, increased number of hospitalizations, graft failure, and patient mortality. Herein, we propose an innovative approach to promote medication adherence and improve patient and graft outcomes.
Gender:
ALL
Ages:
Between 10 years and 21 years
Trial Updated:
02/25/2025
Locations: FSU College of Medicine, Tallahassee, Florida
Conditions: Heart Transplant Rejection, Immune Suppression, Pediatric Heart Transplant, Medication Nonadherence, Health Behavior, Remote Monitoring, Patient Engagement
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