There are currently 980 clinical trials in Tampa, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Moffitt Cancer Center, University of South Florida, H. Lee Moffitt Cancer Center and Research Institute and Tampa General Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer
Recruiting
This study is being done to answer the following question: Is the chance of cancer spreading or returning the same if radiotherapy to the neck is guided, by using a special imaging study called lymph node mapping (lymphatic mapping) Single Photon Emission Computed Tomography (SPECT-CT), compared to the usual treatment when radiotherapy is given to both sides of the neck?
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Moffitt Cancer Center-International Plaza, Tampa, Florida +2 locations
Conditions: Oropharyngeal Cancer
A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
Recruiting
The purpose of this study is to determine if an investigational drug can prevent Bronchopulmonary Dysplasia, reducing the burden of chronic lung disease in extremely premature infants, as compared to extremely premature infants receiving standard neonatal care alone.
Gender:
All
Ages:
Between 0 hours and 24 hours
Trial Updated:
05/13/2024
Locations: Tampa General Hospital, Tampa, Florida
Conditions: Retinopathy of Prematurity (ROP), Intraventricular Hemorrhage, Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity
Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome
Recruiting
This study will determine the safety profile, maximum tolerated dose (MTD), dose-limiting toxicities (DLT), and recommended Phase 2 dose (RP2D) of SX-682 in the treatment of patients with Myelodysplastic Syndromes (MDS).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Myelodysplastic Syndromes
Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)
Recruiting
To compare the efficacy and safety in subjects with advanced or metastatic LMS previously treated with an anthracycline.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/10/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Soft Tissue Sarcoma
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
Recruiting
The objectives of this registry study are to evaluate real-world clinical outcomes and patient reported outcomes that measure the effectiveness and safety of STaRT.
Gender:
All
Ages:
All
Trial Updated:
05/10/2024
Locations: Florida Health Sciences Center, Inc. d/b/a Tampa General Hospital, Tampa, Florida
Conditions: Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma
EPI-7386 in Combination With Enzalutamide Compared With Enzalutamide Alone in Subjects With mCRPC
Recruiting
This is a Phase 1/2 study of EPI-7386 orally administered in combination with enzalutamide in subjects with mCRPC. Phase 1 of the study will be a single-arm dose escalation study of EPI-7386 in combination with a fixed dose of enzalutamide. This portion of the study will primarily evaluate the safety and tolerability of the drug combination and establish the RP2CDs for EPI-7386 and enzalutamide when dosed in combination. In addition, blood sampling will be conducted for PK evaluation to assess... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Prostate Cancer
The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia
Recruiting
Older adults at risk for dementia show a variety of cognitive deficits, which can be ameliorated by different cognitive training (CT) exercises. The best combination of CT exercises is unknown. The aim is to discover the most efficacious combination of CT exercises as compared to cognitive stimulation (which will serve as a stringent, active control) to modify the functional trajectories of older adults' with MCI, who are at high risk for dementia. The primary objective of the U01 phase was to d... Read More
Gender:
All
Ages:
Between 55 years and 89 years
Trial Updated:
05/09/2024
Locations: University of South Florida, Tampa, Florida
Conditions: Age-related Cognitive Decline, Mild Cognitive Impairment, Dementia
A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia
Recruiting
The purpose of the study is to evaluate the efficacy of olezarsen as compared to placebo on the percent change in fasting triglycerides (TG) from baseline.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2024
Locations: VICIS Clinical Research, Tampa, Florida
Conditions: Severe Hypertriglyceridemia
ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC
Recruiting
In this Phase 2 study, mCRPC patients with PSMA positive scans who progressed on prior ARTA and up to 2 lines of taxanes, and are naïve to lutetium Lu 177 vipivotide tetraxetan, will be enrolled. The study is open-label, randomized with active control, multi-center study.
Gender:
Male
Ages:
18 years and above
Trial Updated:
05/09/2024
Locations: Moffitt Cancer Cancer- 1605, Tampa, Florida
Conditions: Metastatic Castration-resistant Prostate Cancer
Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials
Recruiting
This is a single group, Phase 2, long-term extension study for treatment. The purpose of this study is to characterize the safety and efficacy of amlitelimab in treated adult participants with moderate to severe AD who have previously been enrolled in an amlitelimab clinical trial. Visits during the on-treatment period will be at Week 0, 1, 2, 4 and every 4 weeks (Q4W) thereafter. If remote visits are considered appropriate for participants instead of clinic visits at the timepoints indicated in... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2024
Locations: Alliance Clinical Research - Tampa Site Number : 8401013, Tampa, Florida
Conditions: Dermatitis Atopic
A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia
Recruiting
The purpose of this study is to evaluate the efficacy of olezarsen as compared to placebo on the percent change in fasting triglycerides (TG) from baseline.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2024
Locations: R & B Medical Center LLC, Tampa, Florida +1 locations
Conditions: Severe Hypertriglyceridemia
Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors
Recruiting
The purpose of this study is to evaluate the safety and efficacy of targeted blood brain barrier disruption with Exablate Model 4000 Type 2.0/2.1 for liquid biopsy in subjects with suspected Glioblastoma brain tumors
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/09/2024
Locations: Tampa General Hospital, Tampa, Florida
Conditions: Glioblastoma, Glioma, Liquid Biopsy