There are currently 2029 clinical trials in Chicago, Illinois looking for participants to engage in research studies. Trials are conducted at various facilities, including Northwestern University, Rush University Medical Center, University of Chicago and University of Chicago Comprehensive Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age
Recruiting
Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental impairments (NDI) at significant rates, disproportionate to their term peers. Early detection and intervention are critical to mitigate the impact of these impairments. Mechanisms leading from premature birth to these undesirable outcomes remain unclear, and accurate prognostic me... Read More
Gender:
ALL
Ages:
Between 30 weeks and 83 months
Trial Updated:
12/03/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Premature Birth, Asthma in Children, Sleep-Disordered Breathing, Neurodevelopmental Disorders
Antidepressant Effects of Nitrous Oxide
Recruiting
To evaluate the acute and sustained antidepressant effects of nitrous oxide in people with major depressive disorder; and further evaluate these effects by identifying the optimal dose and regimen to guide current practice, and to plan a future large pragmatic trial.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Chicago Medicine, Chicago, Illinois
Conditions: Major Depressive Disorder, Treatment Resistant Depression
Enhancing Immune Health Randomized Controlled Trial
Recruiting
This study tests a psychosocial intervention to improve immune health literacy and behaviors among adults with mental illnesses.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Illinois Chicago, Chicago, Illinois
Conditions: Mental Disorder
Effects of Vibration on Motor Function of Survivors of Chronic Stroke
Recruiting
The aim of this study is to evaluate how vibration of the tendons enhances arm and hand training in survivors of chronic stroke. The investigators hypothesize that wrist/elbow robotic training, combined with body awareness training will improve arm and hand function in individuals with chronic stroke.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
12/03/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Stroke, Healthy
A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer
Recruiting
By doing this study, the research team would like to learn if using a blood test that measures the amount of tumor DNA in blood can help guide how to use chemotherapy combined with immunotherapy for individuals with head and neck cancer. Using this blood test, the research team hopes to learn if intermittent (occasional) chemotherapy added to immunotherapy will work better than immunotherapy alone. Participation in this research will last about two years.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2024
Locations: University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Conditions: Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Head and Neck Neoplasms, Head Cancer, Throat Carcinoma
C-STAR Movement Database
Recruiting
The purpose of this study is to develop a database that contains movement and rehabilitation-related data collected through the use of wearable sensors and video. This database will serve as a resource for clinicians and researchers interested in the investigation of movement or rehabilitation-related research ideas.
Gender:
ALL
Ages:
99 years and below
Trial Updated:
12/02/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Stroke, Parkinson Disease, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
Executive Function and Parenting in Childhood
Recruiting
Deficits in executive functioning (EF) disproportionately impact children living in poverty and increase risk for psychopathology, particularly disruptive behavior disorders. This randomized clinical trial seeks to determine whether childhood EF, assessed across neural and behavioral units of analysis, is an experimental therapeutic target that can be directly modified through caregiver participation in the Chicago Parent Program (CPP), if increases in EF predict reduced disruptive behavior traj... Read More
Gender:
ALL
Ages:
4 years and above
Trial Updated:
12/02/2024
Locations: University of Illinois-Chicago, Chicago, Illinois
Conditions: Disruptive Behavior Disorder, Childhood Onset, Disruptive Behavior, Executive Function
Black and African Americans Connections to Parkinson's Disease (BLAAC PD)
Recruiting
BLAAC PD is a research study to understand what Parkinson's disease looks like for Black and African American communities. BLAAC PD is happening at research centers around the United States. The study is part of the Global Parkinson's Genetics Program (GP2). GP2 is a research project working to transform understanding of the genetics of Parkinson's disease and make that knowledge globally relevant.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2024
Locations: Rush University, Chicago, Illinois +1 locations
Conditions: Parkinson Disease
Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors
Recruiting
This phase II trial tests how well pemetrexed works in treating patients with urothelial bladder cancer and other solid tumors that have spread from where they first started (primary site) to other places in the body (metastatic) with mutations that result in a loss of function in the MLL4-protein/KMT2D-gene or UTX-protein/KDM6A-gene or MTAP enzyme. Loss of function due to a genetic mutation means a gene's activity may be reduced or eliminated. Mutations that result in a loss of function in the... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/27/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Metastatic Bladder Urothelial Carcinoma, Metastatic Malignant Solid Neoplasm, Stage IV Bladder Cancer AJCC v8
Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
Recruiting
An increase in early-onset colorectal cancers (eoCRC), defined as a CRC before 50 years, is confirmed globally. CRC pathogenesis has been associated with several risk factors (family history, germline pathogenic variants, obesity, alcohol, physical activity, red meat, and a Western diet). Design: an international, multicenter, retrospective case-control study of prospectively enrolled patients; low-risk intervention study as it will perform a fecal occult blood test Endpoint: predictive power... Read More
Gender:
ALL
Ages:
Between 18 years and 49 years
Trial Updated:
11/26/2024
Locations: Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine University of Chicago Medicine, Chicago, Illinois
Conditions: Colorectal Cancer, Early Onset Colorectal Cancer, Diet Habit, Risk Reduction
Comparison of Two Sedation Regimens for Awake Fiberoptic Intubation
Recruiting
The purpose of this study is to examine the effects of different sedation drugs used for the awake fiberoptic intubation procedure. Benzodiazapines and narcotics (such as midazolam and fentanyl) are standard drugs used for sedation during awake fiberoptic intubation. Dexmedetomidine, midazolam, and fentanyl are approved by the Food and Drug Administration (FDA) procedural sedation. These drugs might be given to the patient regardless of their participation in the study. In addition to midazolam... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/26/2024
Locations: University of Illinois, Chicago, Illinois
Conditions: Awake Fiberoptic Intubation, Difficult Airway
Mindfulness, Exercise, and Nutrition To Optimize Resilience (MENTOR)
Recruiting
The Mindfulness, Nutrition and Exercise to Optimize Resilience (MENTOR) program is offered through the National Center on Health, Physical Activity and Disability (NCHPAD). NCHPAD is funded by the Centers for Disease Control and Prevention (CDC), is a public health practice that offers health promotion programs and resources to people with mobility disabilities. The purpose of this project is to provide a free-of-charge wellness program designed to improve health and wellness for people with mob... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/26/2024
Locations: Shirley Ryan Ability Lab, Chicago, Illinois
Conditions: Disabled Persons