There are currently 1572 clinical trials in Baltimore, Maryland looking for participants to engage in research studies. Trials are conducted at various facilities, including Johns Hopkins University, Johns Hopkins Hospital, University of Maryland and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)
NCT04485559
Recruiting
This phase I trial studies the side effects and best dose of trametinib and everolimus in treating pediatric and young adult patients with gliomas that have come back (recurrent). Trametinib acts by targeting a protein in cells called MEK and disrupting tumor growth. Everolimus is a drug that may block another pathway in tumor cells that can help tumors grow. Giving trametinib and everolimus may work better to treat low and high grade gliomas compared to trametinib or everolimus alone.
Gender:
All
Ages:
Between 1 year and 25 years
Trial Updated:
04/15/2024
Locations: John Hopkins University, Baltimore, Maryland
Conditions: Recurrent World Health Organization (WHO) Grade II Glioma, Low-grade Glioma, High Grade Glioma
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Quality of Pediatric Resuscitation in a Multicenter Collaborative
NCT02708134
Recruiting
This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of the study is to determine the association between chest compression mechanics (rate, depth, flow fraction, compression release) and patient outcomes. In addition, the investigators will determine the association of post cardiac arrest care with patient outcomes.
Gender:
All
Ages:
Between 0 years and 17 years
Trial Updated:
04/12/2024
Locations: The Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Cardiac Arrest, Cardiopulmonary Arrest
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Study of Anitocabtagene-autoleucel in Relapsed or Refractory Multiple Myeloma (iMMagine-1)
NCT05396885
Recruiting
A Phase II study of anitocabtagene-autoleucel (formerly CART-ddBCMA) for patients with relapsed or refractory multiple myeloma. Anitocabtagene-autoleucel is a BCMA-directed CAR-T cell therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/12/2024
Locations: University of Maryland School of Medicine Greenebaum Comprehensive Cancer Center, Baltimore, Maryland +1 locations
Conditions: Multiple Myeloma
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Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
NCT00904241
Recruiting
This research trial studies biomarkers in tumor tissue samples from patients with newly diagnosed neuroblastoma or ganglioneuroblastoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
Gender:
All
Ages:
30 years and below
Trial Updated:
04/12/2024
Locations: University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland +2 locations
Conditions: Ganglioneuroblastoma, Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma, Regional Neuroblastoma, Stage 4 Neuroblastoma, Stage 4S Neuroblastoma
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Behavioral and Neural Representations of Subjective Effort Cost
NCT04041154
Recruiting
The goal of this proposal is to understand the common and distinct behavioral and neural representations of subjective effort valuation, and how these representations are influenced by fatigue and changes in motivation. It is hypothesized that the brain will use overlapping and distinct neural circuits to represent cognitive and physical effort value, and that fatigue and enhanced motivation will influence the subjective value of effort.
Gender:
All
Ages:
Between 18 years and 35 years
Trial Updated:
04/12/2024
Locations: Kennedy Krieger Institute, Baltimore, Maryland
Conditions: Fatigue
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Eversense® Non-adjunctive Use Post Approval Study
NCT04836546
Recruiting
This is a non-blinded, prospective, multi-center, single arm longitudinal cohort study (patient serving as their own control), to evaluate the effectiveness of diabetes with the Eversense CGM System non-adjunctively compared to self-monitoring of blood glucose (SMBG) using a blood glucose (BG) meter in participants with either Type 1 or Type 2 diabetes. Subjects will serve as their own control, with their baseline based on using SMBG to manage their diabetes for the first 6 months followed by us... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: MODEL Clinical Research, Baltimore, Maryland
Conditions: Diabetes
Register for Updates
Dinner Time for Obesity and Prediabetes
NCT05745441
Recruiting
Obesity and its metabolic complications are leading causes of global morbidity and mortality. Evidence is mounting that inappropriate timing of food intake contributes to obesity. Specifically, late eating is associated with greater weight gain and metabolic syndrome. However, the mechanism by which late eating harms metabolism is not fully understood but may be related to mis-timing of food intake in relation to the body's endogenous circadian rhythm. Conversely, harmonization of eating timing... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
04/10/2024
Locations: Johns Hopkins Bayview Medical Center, Baltimore, Maryland
Conditions: PreDiabetes, Obesity, Healthy
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Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
NCT00736749
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
All
Ages:
All
Trial Updated:
04/10/2024
Locations: Sinai Hospital of Baltimore, Baltimore, Maryland +1 locations
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
Register for Updates
Ocular Blood Flow Imaging for Glaucoma Assessment
NCT05726058
Recruiting
The goal of this clinical trial is to investigate the use of an FDA-cleared retinal blood flow imaging instrument called the XyCAM RI and XyCAM FC (Vasoptic Medical, Inc., Columbia, MD) in glaucoma management. The main question it aims to answer are: Can the investigators use blood flow to discriminate between eyes with early-stage glaucoma and variable-matched controls? Can the investigators validate that the XyCAM FC simultaneously captures both stereo fundus photography and ocular blood flo... Read More
Gender:
All
Ages:
Between 18 years and 88 years
Trial Updated:
04/09/2024
Locations: University of Maryland Eye Associates at Redwood, Baltimore, Maryland
Conditions: Glaucoma
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Scrambler Therapy for Corticobasal Syndrome-Associated Pain
NCT05653778
Recruiting
The goal of this pilot trial is to test whether scrambler therapy (ST) is an effective treatment for neuropathic pain in patients with corticobasal syndrome (CBS). The main question it aims to answer is: Will ST reduce pain scores by at least 33% at one month in this pilot trial, justifying further multi-center trials? Participants will: be randomly assigned treatment from either transcutaneous electrical nerve stimulation (TENS) or ST for pain initially (eventually all patients will receive... Read More
Gender:
All
Ages:
Between 50 years and 89 years
Trial Updated:
04/09/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Corticobasal Degeneration, Corticobasal Syndrome, Pain, Neuropathic
Register for Updates
Music Therapy for Patients With Alzheimer's Disease
NCT05151562
Recruiting
This study is designed to assess the feasibility that individualized reminiscence-based virtual music therapy sessions can enhance autobiographical memory, mood, and cognition in patients with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's Disease (AD). 60 patients with MCI or mild dementia due to AD will receive two 30 minutes reminiscence-targeted virtual music therapy interventions per week for 8 weeks (a total of 16 sessions). Participants' (or supported by the study p... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
04/09/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Mild Cognitive Impairment, Alzheimer Disease
Register for Updates
Effects of RAS on Gait in PD Patients With DBS
NCT05763732
Recruiting
Participants will be asked to walk along with the metronome beats (RAS) during the participants' stimulation state (ON or OFF) for four minutes for each state. The researcher will collect the gait parameters (cadence, velocity, and stride length) of patients before, during, and after RAS in both DBS ON and OFF states. Using MDS-UPDRS, participants' gait patterns will be collected before and after RAS while both DBS is ON and OFF. Electrophysiological activity (local field potentials, LFPs) wil... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
04/09/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Parkinson Disease
Register for Updates