There are currently 1535 clinical trials in Baltimore, Maryland looking for participants to engage in research studies. Trials are conducted at various facilities, including Johns Hopkins University, Johns Hopkins Hospital, University of Maryland and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Trial of CORT108297 to Attenuate the Effects of Acute Stress in the Allocortex (CORT-X)
NCT04601038
Recruiting
CORT-X will examine if mitigation of stress-mediated pathogenesis of Alzheimer's disease (AD) is a feasible target for intervention in individuals at risk for this disease. This single-site (Baltimore, Maryland) phase II clinical trial is a 2-week, randomized, placebo-controlled crossover study of the effects of the selective glucocorticoid receptor antagonist, CORT108297, on cognitive test performance in 26 individuals with mild cognitive impairment (MCI) due to AD and in 26 cognitively normal... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
07/17/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Mild Cognitive Impairment, Alzheimer Disease, Memory Impairment
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Behavioral Weight Loss for Cancer Survivors in Maryland: A Trial With Adaptive Interventions
NCT06463249
Recruiting
The objective of the HELPLINE Weight Loss Program is to determine the comparative effectiveness of two active multi-component, augmented interventions for cancer survivors with overweight or obesity who do not achieve early weight loss goal in the initial intervention period (termed, early non-responders). The core study design is randomized controlled trial with adaptive intervention. 1. CORE Helpline in all participants (first 2 months) 2. Extended Helpline in early responders (additional 6 m... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/16/2024
Locations: Johns Hopkins ProHealth, Baltimore, Maryland
Conditions: Weight Loss
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Pancreatic Cancer Registry: For Any Person With a Personal or Family History
NCT02886247
Recruiting
The NFPTR was established in 1994 to find the causes of pancreatic cancer. In brief, the investigators are interested in both the genetic and non-genetic causes of pancreatic cancer. The investigators are particularly interested in finding the genes that cause pancreatic cancer to cluster in some families. Up to 10% of pancreatic cancer patients have another close relative who has also developed pancreatic cancer. This clustering of pancreatic cancers in families has yet to be explained; however... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/16/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Pancreatic Cancer, ATM, BRCA, Hereditary Cancer
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Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma
NCT05141513
Recruiting
This study is designed to investigate the safety of intraoperative radiation therapy (IORT) in patients with localized pancreatic cancer undergoing surgical resection after neoadjuvant chemotherapy and stereotactic body radiation therapy (SBRT).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Pancreatic Cancer
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Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow
NCT04254185
Recruiting
This research is studying two surgical procedures in a large group of people to learn about how well these procedures work as a treatment for ulnar neuropathy at the elbow (UNE). Researchers want to see which surgery is more helpful for people with ulnar neuropathy. This research will determine if one surgery is better than the other to alleviate symptoms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: Johns Hopkins University, Baltimore, Maryland +1 locations
Conditions: Neuropathy Ulnar
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Safety and Feasibility of Hyperkalemic Cardioplegia With Diazoxide in Cardiac Surgery (CPG-DZX) Trial
NCT06308107
Recruiting
This study aims to confirm the safety and efficacy of diazoxide as an additive to hyperkalemic cardioplegia in patients undergoing cardiac surgery with cardiopulmonary bypass. The investigators hypothesize that diazoxide combined with hyperkalemic cardioplegia provides superior myocardial protection and reduced myocardial stunning compared with standard cardioplegia alone. Thirty patients will receive treatment. Safety will be assessed by comparing mean arterial blood pressure measurements, gluc... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Myocardial Stunning
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Evaluate the Effect of Atorvastatin on Cerebrovascular Reactivity in Mild Cognitive Impairment (MCI)
NCT04765137
Recruiting
The purpose of this study is to evaluate the effect of atorvastatin on brain vessel reactivity and with it on blood flow in people with mild cognitive impairment.
Gender:
ALL
Ages:
Between 60 years and 95 years
Trial Updated:
07/10/2024
Locations: Johns Hopkins University, Bayview Medical Center, Baltimore, Maryland
Conditions: Mild Cognitive Impairment
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ARrest RESpiraTory Failure From PNEUMONIA
NCT04193878
Recruiting
This research study seeks to establish the effectiveness of a combination of an inhaled corticosteroid and a beta agonist compared to placebo for the prevention of acute respiratory failure (ARF) in hospitalized patients with pneumonia and hypoxemia.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2024
Locations: University of Maryland, Baltimore, Maryland +1 locations
Conditions: Pneumonia, Hypoxemia, Acute Respiratory Failure, COVID-19 Pneumonia
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Effects of Simvastatin on Uterine Leiomyoma Size
NCT03400826
Recruiting
The study aims to study the effect of simvastatin on the size of uterine fibroids.
Gender:
FEMALE
Ages:
Between 18 years and 55 years
Trial Updated:
07/10/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Fibroid Uterus, Fibroid Tumor, Leiomyoma, Fibromyoma, Leiomyoma, Uterine
Register for Updates
The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry
NCT02346435
Recruiting
Retrospective studies indicate that active surveillance for clinically localized, small renal masses (cT1a, \<=4cm) is safe. It is our hypothesis that active surveillance is safe and efficacious when compared prospectively to patients undergoing immediate intervention for their small renal mass.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/08/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Kidney Neoplasm
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Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment
NCT03891160
Recruiting
The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to study the correlation of having a 3D printed model with improvement in patient outcomes and compare those with patients who have had a VAD placement without a 3D model.
Gender:
ALL
Ages:
All
Trial Updated:
07/03/2024
Locations: Johns Hopkins, Baltimore, Maryland
Conditions: Congenital Heart Disease
Register for Updates
Robot Aided Rehabilitation - Intervention
NCT02359253
Recruiting
Sensorimotor impairments following stroke often involve complex pathological changes across multiple joints and multiple degrees of freedom of the arm and hand, thereby rendering them difficult to diagnose and treat. The objective of this study is to evaluate multi-joint neuromechanical impairments in the arm and hand, then conduct impairment-specific treatment, and determine the effects of arm versus hand training and the effects of passive stretching before active movement training.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
07/02/2024
Locations: University of Maryland, Baltimore, Baltimore, Maryland
Conditions: Stroke
Register for Updates