There are currently 1599 clinical trials in Baltimore, Maryland looking for participants to engage in research studies. Trials are conducted at various facilities, including Johns Hopkins University, Johns Hopkins Hospital, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins and University of Maryland. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Prone Positioning During Delayed Cord Clamping
NCT05507424
Recruiting
Delayed cord clamping is a routine technique used in the delivery room. The baby remains attached to the umbilical cord and placenta for 30-60 seconds after birth to allow for maximal transfer of oxygen and blood to the newborn. This study seeks to determine the best position (on the back versus on the belly) for the newborn during the 30-60 seconds of delayed cord clamping.
Gender:
Female
Ages:
Between 18 years and 55 years
Trial Updated:
08/04/2023
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Delayed Cord Clamping
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Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement Study
NCT05977881
Recruiting
Through the proposed Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement (SCOPE) study, the investigators will design and evaluate an overdose prevention and HIV prevention study among people who use drugs (PWUD). Specifically, SCOPE will provide access to drug-checking services for PWUD to better understand the contents of the drug supply, in combination with PrEP for those who are HIV-, to both reduce overdose and HIV among PWUD in Baltimore City.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/03/2023
Locations: Johns Hopkins School of Public Health, Baltimore, Maryland
Conditions: HIV Infections
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Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer
NCT03186898
Recruiting
This phase III trial studies how well radiation therapy with protons works compared with photons in treating patients with liver cancer. Radiation therapy, such as photon therapy, uses high energy x-rays to send the radiation inside the body to the tumor while proton therapy uses a beam of proton particles. Proton therapy can stop shortly after penetrating through the tumor and may cause less damage to the surrounding healthy organs and result in better survival in patients with liver cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/31/2023
Locations: Maryland Proton Treatment Center, Baltimore, Maryland +1 locations
Conditions: Unrectable or Locally Recurrent Hepatocellular Carcinoma
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Investigation on the Bidirectional Cortical Neuroprosthetic System
NCT03161067
Recruiting
The Bidirectional Cortical Neuroprosthetic System (BiCNS) consists of NeuroPort Microelectrode Array Systems and NeuroPort Electrodes (Sputtered Iridium Oxide Film), Patient Pedestals, the NeuroPort BioPotential Signal Processing System, and the CereStim C96 Programmable Stimulator. The goals of this early feasibility study consist of safety and efficacy evaluations of this device.
Gender:
All
Ages:
Between 22 years and 65 years
Trial Updated:
07/31/2023
Locations: Department of Physical Medicine and Rehabilitation, Baltimore, Maryland
Conditions: Tetraplegia, Quadriplegia
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Predicting Progression of Developing Myeloma in a High-Risk Screened Population (PROMISE)
NCT03689595
Recruiting
The PROMISE Study aims to establish a prospective cohort of individuals with precursor conditions to multiple myeloma, such as monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). We will study these patients as a means to identify risk factors for progression to symptomatic multiple myeloma.
Gender:
All
Ages:
30 years and above
Trial Updated:
07/30/2023
Locations: The Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Multiple Myeloma
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HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia
NCT04131413
Recruiting
The primary goal of this phase I open label study is to determine the safety and tolerability of pNGVL4aCRTE6E7L2 DNA vaccine, as administered by intramuscular (IM) injection with TriGrid™ electroporation to both HIV- or HIV+ adult female subjects (≥ 19 years), with biopsy confirmed cervical intraepithelial (CIN) II or III that is human papillomavirus (HPV) 16+.
Gender:
Female
Ages:
19 years and above
Trial Updated:
07/27/2023
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Human Papillomavirus Type 16, Cervical Intraepithelial Neoplasia Grade II, Cervical Intraepithelial Neoplasia, Grade III
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Pancreatic Cancer Registry: For Any Person With a Personal or Family History
NCT02886247
Recruiting
The NFPTR was established in 1994 to find the causes of pancreatic cancer. In brief, the investigators are interested in both the genetic and non-genetic causes of pancreatic cancer. The investigators are particularly interested in finding the genes that cause pancreatic cancer to cluster in some families. Up to 10% of pancreatic cancer patients have another close relative who has also developed pancreatic cancer. This clustering of pancreatic cancers in families has yet to be explained; however... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/26/2023
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Pancreatic Cancer, ATM, BRCA, Hereditary Cancer
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Hyperthermia Treatment Added to Chemotherapy Standard of Care for Pancreatic Tumors
NCT05959395
Recruiting
In this study, tumors of the pancreas are treated with a device placed around the abdomen that creates an electromagnetic field that generates heat in the tumor. Heating the tumor improves blood flow and the delivery of chemotherapy to the tumor as has been shown in numerous studies for various cancers with potential clinical benefits. Subjects will receive the thermal treatment on the same day and prior to receiving standard of care chemotherapy for a total of 4 treatments. This study is an ear... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/26/2023
Locations: University of Maryland, Baltimore, Maryland
Conditions: Pancreatic Cancer
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BGC101 (EnEPC) Autologous Cell Therapy From Patient's Own Blood for Treatment of Critical Limb Ischemia (CLI)
NCT02805023
Recruiting
Evaluate the feasibility of an autologous cell preparation composed of a mixture of cells enriched for endothelial progenitor cells (EnEPCs) and multipotent adult hematopoietic stem/progenitor cells (HSPC) (BGC101), in the treatment of patients suffering from peripheral arterial disease (PAD) with critical limb ischemia (CLI) who have not responded to optimal pharmacological treatment or control of risk factors and/or had a revascularization failure, and do not have the option of further revascu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/25/2023
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Critical Limb Ischemia, Peripheral Arterial Disease, Peripheral Vascular Disease
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Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy
NCT05337631
Recruiting
The number of elderly head-and-neck squamous cell carcinoma (HNSCC) patients is increasing; however, the evidence regarding the ideal treatment for this often vulnerable and frail patient cohort is limited. Although the benefit of concomitant chemotherapy has been reported to decrease in elderly HNSCC patients based on the MACH-NC meta-analysis, it remains unknown whether state-of-the art radiotherapy techniques such as intensity-modulated radiotherapy (IMRT), modern supportive treatments and al... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
07/21/2023
Locations: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: HNSCC, Oral Cavity Cancer, Oropharynx Cancer, Hypopharynx Cancer, Larynx Cancer
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Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study
NCT03808922
Recruiting
This study will seek to enroll immunocompromised patients with Lower Tract parainfluenza infection. It also contains a sub-study to enroll patients with severe COVID-19.
Gender:
All
Ages:
All
Trial Updated:
07/19/2023
Locations: University of Maryland, Baltimore, Maryland +1 locations
Conditions: Lower Respiratory Tract Infection, Parainfluenza, Immunocompromised, COVID-19
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Healthy for Two-Home Visiting (H42-HV): Health Coaching for Pregnant Women
NCT05619705
Recruiting
The purpose of this study is to compare the effectiveness of H42-HV integrated into home visiting compared with usual home visiting services in reducing postpartum weight retention (difference between pre-pregnancy weight and weight at 6 months postpartum) among pregnant and postpartum people. The intervention is tailored for Black and Latinx pregnant and postpartum people and, ultimately, aims to address inequities in cardiometabolic health.
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/19/2023
Locations: Johns Hopkins School of Nursing, Baltimore, Maryland
Conditions: Postpartum Weight Retention, Pregnancy Weight Gain, Overweight and Obesity, Behavior, Health
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