There are currently 1573 clinical trials in Baltimore, Maryland looking for participants to engage in research studies. Trials are conducted at various facilities, including Johns Hopkins University, Johns Hopkins Hospital, University of Maryland and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Complex Adult Deformity Surgery (CADS)
Recruiting
Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: John Hopkins University, Department of Orthopedic Surgery, Baltimore, Maryland
Conditions: Adult Spinal Deformity, Scoliosis, Kyphosis, Sagittal Imbalance
Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0
Recruiting
Multi-center, prospective, non-randomized study to evaluate outcomes of surgically treated patients with adult cervical spinal deformity.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Johns Hopkins University, Department of Neurological Surgery, Baltimore, Maryland
Conditions: Cervical Deformity
Study of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene Mutations
Recruiting
Single arm, single site, open-label Phase II study of the effects of oral olaparib in participants with metastatic renal cell carcinoma that harbor an inactivating mutation in BAP-1, ATM, BRCA1, BRCA2, PALB2, CHEK2, BRIP1, RAD51C, BARD1, CDK12, CHEK1, FANCL, PP2R2A, RAD51B, RAD51D, or RAD54L who have had prior treatment with at least one immune checkpoint inhibitor or anti-VEGF therapy. Must have measurable disease on CT imaging per RECIST 1.1 criteria.
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
03/04/2024
Locations: Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
Conditions: Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma, Kidney Cancer, Renal Carcinoma, Kidney Cancer Metastatic
Chemotherapy Induced Peripheral Neuropathy Natural History Study (EPIPHANY)
Recruiting
This is a prospective natural history study of CIPN in approximately 200 participants receiving taxanes (paclitaxel, docetaxel) for breast cancer, bortezomib for multiple myeloma, oxaliplatin-based regimens for colorectal cancer, or vincristine for lymphoma.. Demographic data, medical history, electronic PROs, ClinROs blood biomarkers including NF-L, PGx DNA analyses and Bedside-QST will be assessed at Baseline. The Observation Period will initiate with the first dose of chemotherapy and conclud... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: University of Maryland School of Medicine, Baltimore, Maryland +1 locations
Conditions: Chemotherapy-induced Peripheral Neuropathy
Chronic Pain in Rheumatoid Arthritis
Recruiting
The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. A subset of participants will also undergo magnetic resonance imaging at 0 and 12 months to assess neuroimaging markers that have previously been... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Arthritis, Rheumatoid, Pain
Assessing a Clinically-meaningful Opioid Withdrawal Phenotype
Recruiting
Evaluate individual differences in the expression of opioid withdrawal symptoms in persons with opioid use disorder (OUD) while completing a clinically-indicated medication taper.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/27/2024
Locations: Johns Hopkins University Bayview Medical Campus, Baltimore, Maryland
Conditions: Opioid Withdrawal, Opioid Use Disorder, Opioid Craving
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: University of Maryland School of Medicine, Baltimore, Maryland +1 locations
Conditions: Huntington's Disease
Clinic-based HIV Identification and Prevention Project Using Electronic Resources
Recruiting
Hybrid Type II effectiveness-implementation trial to investigate whether electronic medical and sexual history data collection with HIV risk categorization/scoring will increase pre-exposure prophylaxis (PrEP) uptake among cis-gender women attending routine well-woman gynecologic preventative visits.
Gender:
Female
Ages:
Between 15 years and 65 years
Trial Updated:
02/23/2024
Locations: Johns Hopkins Health System, Baltimore, Maryland
Conditions: HIV Prevention, Primary Care, PrEP
Sensory-Motor Rehabilitation Post Stroke
Recruiting
Early after stroke, patients often have significant motor impairment and sensory deficit. Evidence has demonstrated heightened plasticity and significant recovery in the acute phase (first months) post stroke but there has been a lack of effective and practical protocols and devices for early intensive sensorimotor therapy.This research study will conduct a randomized clinical trial of an intensive motor-sensory rehabilitation on patients with acute stroke using a wearable rehabilitation robot.... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/22/2024
Locations: University of Maryland, Baltimore, Baltimore, Maryland
Conditions: Acute Stroke
Adapt2Quit - An Adaptive Motivational System for Socio-Economically Disadvantaged Smokers
Recruiting
The goal of this research is to test the Adapt2Quit computer program that uses participant input (message rating on how much the text motivational message might influence one to quit smoking) to select and text motivational messages that are more likely to help a user stop smoking. This Adapt2Quit system will be compared with a quitline facilitation-only control (text messages will be sent to facilitate quitline use). The primary research hypothesis is that the Adapt2Quit recommender-selected me... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
02/20/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Tobacco Smoking
Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury
Recruiting
This study will look to validate predictive algorithms developed in a previous study where we collected relevant data from trauma registry and after using advanced signal-processing and machine-learning, determined prediction scores regarding neuroworsening and other outcomes following traumatic brain injury.
Gender:
All
Ages:
Between 18 years and 79 years
Trial Updated:
02/20/2024
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Traumatic Brain Injury
Towards Understanding Between ADT Treatment, Circadian Rhythm, and Physiological Responsiveness
Recruiting
Frailty is one of the main reasons older adults lose independence. Frailty describes a reduced ability to withstand stress on the physiological scale, or a reduced physiological reserve. The theory is that entrainment of circadian rhythm via time-restricted eating will improve the body's ability to predict energy supply and demand, and therefore enable the body to allocate more resources to anabolic processes and promote resilience to cancer treatment, thereby preventing the progression of frail... Read More
Gender:
Male
Ages:
55 years and above
Trial Updated:
02/19/2024
Locations: University of Maryland, Baltimore, Baltimore, Maryland
Conditions: Prostatic Neoplasm, Survivorship, Frailty, Aging