There are currently 213 clinical trials in Columbia, Missouri looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Missouri, Ellis Fischel Cancer Center - Columbia, Ellis Fischel Cancer Center at University of Missouri - Columbia and University of Missouri - Ellis Fischel. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
NCT03053193
Recruiting
The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enable additional study arms at low incremental effort and cost. FLEX Registry will utilize an adaptive design, where additional targeted substudies and arms can be added after the initial study is opened.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/26/2024
Locations: Boone Hospital Center, Columbia, Missouri
Conditions: Breast Cancer
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Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
NCT03610763
Recruiting
This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral nervous system injuries (including hand transplantation, hand replantation, and surgically repaired upper extremity nerve injuries). The technique involves combining behavioral training with transcranial direct current stimulation (tDCS)-a non-invasive form of brain stimulation capable of facilitati... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: University of Missouri, Columbia, Missouri
Conditions: Hand Transplantation, Peripheral Nerve Injuries, Neurologic Rehabilitation
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Routine Validation and Reproducibility Testing of Laboratory Measures and Research Techniques Used for Metabolism Research (VAL)
NCT06286761
Recruiting
The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on chronic diseases (obesity, pre-diabetes and type-2 diabetes, dyslipidemia, non-alcoholic fatty liver disease, cardiovascular disease, etc.), nutrition, and metabolism (the process by which a substance is handled in your body) at the University of Missouri. As technolo... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
06/10/2024
Locations: University of Missouri School of Medicine, Columbia, Missouri
Conditions: Obesity
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Sleep and Pain Interventions in Women With Fibromyalgia
NCT03744156
Recruiting
Insomnia affects 67-88% of chronic pain patients. SPIN II is a randomized controlled clinical trial that will compare the effects of two cognitive behavioral sleep treatments in women with fibromyalgia and insomnia. This trial will yield important information about the roles of sleep, arousal, and brain structure and function in the development and maintenance of chronic pain in women with fibromyalgia.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/10/2024
Locations: University of Missouri- Department of Psychiatry, Columbia, Missouri
Conditions: Fibromyalgia, Insomnia, Chronic Widespread Pain
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Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.
NCT05846438
Recruiting
The goal of this clinical trial is to learn whether showering with surgical drain tubes in place after first stage breast reconstruction causes increased risk of infection. The main questions it aims to answer are: * Is there an increased risk of infection/complications with showering 48 hours after drain tubes are in place * Does showering after 48 hours with drain tubes in place affect quality of life.
Gender:
FEMALE
Ages:
Between 18 years and 100 years
Trial Updated:
05/28/2024
Locations: University of Missouri, Columbia, Missouri
Conditions: Infections, Quality of Life
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Hybrid Telehealth in Pediatric Physical Therapy
NCT05350904
Recruiting
The purposes of this study are to compare the impact of a hybrid of telehealth and in-person physical therapy services to in-person services alone on the in-home functional skills of children with moderate to severe disability. This is a mixed methods study.
Gender:
ALL
Ages:
Between 2 years and 17 years
Trial Updated:
05/24/2024
Locations: University of Missouri, Columbia, Missouri
Conditions: Pediatric Disorder, Disability, Developmental
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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
NCT05390892
Recruiting
PRECIDENTD is a randomized, open label, pragmatic clinical trial designed to compare rates of the total number of cardiovascular, kidney, and death events among two alternative treatments for patients with type 2 diabetes (T2D) and either established atherosclerotic cardiovascular disease (ASCVD) or at high risk for ASCVD. To accomplish this objective, we will randomly assign 6,000 patients with established T2D and ASCVD or high-risk for ASCVD in a 1:1 allocation to sodium-glucose cotransporter-... Read More
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
05/20/2024
Locations: University of Missouri-Columbia, Columbia, Missouri
Conditions: Type2Diabetes, ASCVD
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Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer
NCT04444869
Recruiting
This trial will explore giving standard dose chemotherapy and radiation therapy to sites of disease including all lymph nodes involved with HPV-positive oropharyngeal cancer, but administer lower doses of radiation therapy to the lymph nodes that are not known to be involved with cancer. By doing so, it is hypothesized that there will be equally good long term loco-regional and distant disease control but will reduced long term treatment side effects and improved quality of life in persons livin... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/16/2024
Locations: University of Missouri, Columbia, Missouri
Conditions: Cancer of the Head and Neck, Oropharynx Cancer, HPV Positive Oropharyngeal Squamous Cell Carcinoma, Throat Carcinoma
Register for Updates
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
NCT00736749
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
04/10/2024
Locations: Columbia Regional, Columbia, Missouri
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
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Determination and Validation of a Multi-analyte Assay for Lung Cancer Screening
NCT04968548
Recruiting
This study is part of the development and validation of a non-invasive lung screening test which aim to identify early stage lung cancer in patients at high risk for lung cancer.
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
03/28/2024
Locations: Harry S. Truman Memorial Veterans' Hospital, Columbia, Missouri
Conditions: Lung Cancer
Register for Updates
Collaboration Oriented Approach to Controlling High Blood Pressure
NCT06124716
Recruiting
Hypertension is a significant contributor to poor cardiovascular outcomes. Self-management support tools can increase patient behaviors to improve blood pressure. The investigators created a clinical decision support app, called COACH, to integrate home blood pressure data and goals into EHR reporting and workflow with communications informed by behavioral economics principles to support shared decision-making. The study aims to measure the effectiveness of the COACH intervention in a pragmatic... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
03/22/2024
Locations: University of Missouri-Columbia, Columbia, Missouri
Conditions: Hypertension, Multiple Chronic Conditions
Register for Updates
Targeting Insomnia in School Aged Children With Autism Spectrum Disorder
NCT04545606
Recruiting
Children with Autism Spectrum Disorder (ASD) and insomnia, and their parent(s) will undergo 4 sessions of behavioral therapy for sleep problems followed by 4 bimonthly booster sessions. Children and their families will be randomly assigned to one of three conditions: cognitive behavioral therapy (in-person), cognitive behavioral therapy (remote), or behavioral therapy (remote). Arousal will be measured through heart-rate variability. Sleep and secondary outcomes (child daytime behavior, parent s... Read More
Gender:
ALL
Ages:
Between 6 years and 12 years
Trial Updated:
03/12/2024
Locations: Thompson Center for Autism and Neurodevelopmental Disorders, Columbia, Missouri
Conditions: Insomnia Chronic, Autism Spectrum Disorder
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