The city of Columbia, Missouri, currently has 5 active clinical trials seeking participants for Autism research studies.
ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)
Recruiting
ML-004-002 is a multi-center, randomized, double-blind, parallel-group, placebo-controlled study that will enroll approximately 150 adolescent and adult subjects with ASD. The primary objective is to evaluate the efficacy of ML-004 compared with placebo in the improvement of social communication deficits in subjects with ASD.
Gender:
All
Ages:
Between 12 years and 45 years
Trial Updated:
05/28/2024
Locations: University of Missouri, Thompson Center for Autism & Neurodevelopmental Disorders, Columbia, Missouri
Conditions: Autism Spectrum Disorder
Baker Gordon Syndrome Natural History Study
Recruiting
The goal of this study is to conduct a prospective, longitudinal assessment of the natural clinical progression of children and adults with Synaptotagmin1-Associated Neurodevelopmental Disorder also known as Baker Gordon Syndrome (BAGOS). This will be performed by acquiring baseline measurements and developing effective outcome measures and diagnostic tools for the disorder, to prepare the healthcare system for future clinical trials.
Gender:
All
Ages:
Between 0 years and 99 years
Trial Updated:
05/01/2024
Locations: University of Missouri Columbia, Columbia, Missouri
Conditions: Rare Diseases, Autism or Autistic Traits, Development Delay, SYT-SSX Fusion Protein Expression, Sleep Disorder, Epilepsy, Generalized, Motor Delay
Targeting Insomnia in School Aged Children With Autism Spectrum Disorder
Recruiting
Children with Autism Spectrum Disorder (ASD) and insomnia, and their parent(s) will undergo 4 sessions of behavioral therapy for sleep problems followed by 4 bimonthly booster sessions. Children and their families will be randomly assigned to one of three conditions: cognitive behavioral therapy (in-person), cognitive behavioral therapy (remote), or behavioral therapy (remote). Arousal will be measured through heart-rate variability. Sleep and secondary outcomes (child daytime behavior, parent s... Read More
Gender:
All
Ages:
Between 6 years and 12 years
Trial Updated:
03/12/2024
Locations: Thompson Center for Autism and Neurodevelopmental Disorders, Columbia, Missouri
Conditions: Insomnia Chronic, Autism Spectrum Disorder
International Multicentric Observational Study to Characterize Subpopulations of Patients With Autism Spectrum Disorder
Recruiting
To determine sufficient number of biological and clinical markers to identify subgroups of potential best responders to a specific medication
Gender:
All
Ages:
Between 12 years and 65 years
Trial Updated:
03/01/2024
Locations: University of Missouri, Thompson Center for Autism & Neurodevelopmental Disorders, Columbia, Missouri
Conditions: Autism Spectrum Disorder
Dynamic Quantification of Social-Visual Engagement in Autism Spectrum Disorder (ASD) For Children Ages 31-84 Months
Recruiting
The goal of this clinical study is to learn about the utility and performance of the EarliPoint System (™): Evaluation for Autism Spectrum Disorder to diagnose and assess autism spectrum disorder (ASD) in children ages 31-84 month (2.5 - 7 years chronological age). The main questions it aims to answer are: To determine the sensitivity and specificity of the EarliPoint device (test) compared to Expert Clinician Diagnosis (ECD) using gold-standard clinical reference assessments in the target age... Read More
Gender:
All
Ages:
Between 31 months and 84 months
Trial Updated:
02/02/2024
Locations: ThompsonCenter for Autism & Neurodevelopment; University of Missouri, Columbia, Missouri
Conditions: Autism Spectrum Disorder, Autism