There are currently 212 clinical trials in Columbia, Missouri looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Missouri, Ellis Fischel Cancer Center - Columbia, Ellis Fischel Cancer Center at University of Missouri - Columbia and University of Missouri - Ellis Fischel. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity
NCT04436731
Recruiting
Patients with sleep apnea are at increased risk of developing cardiovascular disease - with women at potentially greater risk than men. Contributing mechanisms are not well understood, but may be related to how women respond to low oxygen and, given over 70% of patients with sleep apnea are obese, the impact of obesity. This project seeks to increase our understanding of mechanisms that may contribute to sex differences in the cardiovascular response to low oxygen with the hope that this knowled... Read More
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
04/03/2023
Locations: University of Missouri-Columbia, Columbia, Missouri
Conditions: Obesity, Healthy, Vasoconstriction, Vasodilation
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Ketogenic Diet for Traumatic Brain Injury
NCT03982602
Recruiting
Traumatic Brain Injury is a major health concern in United States. There is a un-met need to develop new therapeutic options for faster neuron recovery without causing significant side effects. The role of ketones in neuronal recovery has been studied and has been found to be useful in decreasing size of contusion. The present study aims to study the safety and feasibility profile of ketogenic diet.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/28/2023
Locations: University of Missouri Hospital, Columbia, Missouri
Conditions: Traumatic Brain Injury, Ketogenic Dieting
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Hybrid Telehealth in Pediatric Physical Therapy
NCT05350904
Recruiting
The purposes of this study are to compare the impact of a hybrid of telehealth and in-person physical therapy services to in-person services alone on the in-home functional skills of children with moderate to severe disability. This is a mixed methods study.
Gender:
All
Ages:
Between 2 years and 17 years
Trial Updated:
03/22/2023
Locations: University of Missouri, Columbia, Missouri
Conditions: Pediatric Disorder, Disability, Developmental
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Randomized Therapy In Status Epilepticus
NCT04391569
Recruiting
This study will evaluate the effectiveness and safety of an investigational product (IP), intravenous (IV) ganaxolone, to treat participants with status epilepticus (SE).
Gender:
All
Ages:
12 years and above
Trial Updated:
02/22/2023
Locations: Marinus Research Site, Columbia, Missouri
Conditions: Status Epilepticus
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Connect® Myeloid Disease Registry
NCT01688011
Recruiting
The purpose of the Connect® Myeloid disease registry is to provide unique insights into treatment decisions and treatment patterns as they relate to clinical outcomes of patients with myeloid diseases in routine clinical practice. This disease registry will also evaluate molecular and cellular markers that may provide further prognostic classification which may or may not be predictive of therapy and clinical outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/25/2022
Locations: Harry S Truman Memorial Veterans' Hospital, Columbia, Missouri
Conditions: Myelodysplastic Syndromes, Primary Myelofibrosis, Leukemia, Myeloid, Acute
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Sleep Treatment for Addiction Recovery
NCT04198311
Recruiting
Project STAR aims to examine the feasibility, acceptability, and initial efficacy of a CBT-I supplement to outpatient alcohol and substance use treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/06/2022
Locations: University of Missouri-Columbia, Columbia, Missouri
Conditions: Insomnia, Alcohol Use Disorder, Substance Use Disorders
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Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer
NCT05486143
Recruiting
This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbociclib for the treatment of patients with locally advanced or metastatic HR+/HER2- breast cancer following progression on or after CDK4/6 and aromatase inhibitor therapy. Condition or disease: Breast Cancer Intervention/treatment: Drug: Gedatolisib Drug: Palbociclib Drug: Fulvestrant Drug: Alpelisib Phase 3
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2022
Locations: University of Missouri Health Care, Columbia, Missouri
Conditions: Breast Cancer
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NOVOCART®3D for Treatment of Articular Cartilage of the Knee
NCT01957722
Recruiting
This study is to compare NOVOCART 3D relative to Microfracture for the treatment of knee cartilage defects. Efficacy will be evaluated by both pain and function. Safety will also be evaluated.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/01/2022
Locations: University of Missouri Healthcare, Columbia, Missouri
Conditions: Articular Cartilage of the Femoral Condyle Between 2-6cm2
Register for Updates