There are currently 206 clinical trials in Columbia, Missouri looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Missouri, Ellis Fischel Cancer Center - Columbia, Ellis Fischel Cancer Center at University of Missouri - Columbia and University of Missouri - Ellis Fischel. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia
NCT05256069
Recruiting
The purpose of this project is to identify sex-related differences in the effect of hypoxia on sympathetic vascular transduction.
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
05/13/2024
Locations: University of Missouri-Columbia, Columbia, Missouri
Conditions: Vasodilation, Hypoxia
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Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)
NCT04365374
Recruiting
This trial will be a randomized controlled study comparing the efficacy and safety of intraoperative radiation therapy using GammaTilesTM (GT) versus SRT 3-4 weeks following metastatic tumor resection which is the current standard of care.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Ellis Fischel Cancer Center at University of Missouri, Columbia, Missouri
Conditions: Brain Metastases
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Effects of a Personalized Diet on Cardiometabolic, Microbiome and Metabolomics Profiles in Minority Young Adults
NCT04635917
Recruiting
The proposed study has two primary objectives i.e. to examine how improvements in diet quality via a personalized dietary intervention 1) benefit cardiometabolic outcomes in young Black adults differentially compared to non-Hispanic White adults, and 2) improve carbohydrate and lipid metabolism in relation to the gut microbiome.
Gender:
All
Ages:
Between 18 years and 35 years
Trial Updated:
05/10/2024
Locations: University of Missouri-Columbia, Columbia, Missouri
Conditions: Diet Intervention
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Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
NCT05624450
Recruiting
The purpose of this study is to evaluate the effect of tozorakimab, as an add-on to SoC in patients with viral lung infection requiring supplemental oxygen, on the prevention of death or progression to IMV/ECMO.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2024
Locations: Research Site, Columbia, Missouri
Conditions: Viral Lung Infection and Acute Respiratory Failure
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Sex-specific Effect of Restricted Sleep on Brain Health
NCT05920759
Recruiting
The goal of this clinical trial is to compare the impact of restricted sleep on brain blood health in healthy men and women. The main question[s] it aims to answer are: Whether morning cerebral blood flow velocity is greater following a night of normal sleep compared to restricted sleep Whether the effect of sleep restriction on cerebral blood flow will be greater in males compared to females Participants will complete one 1-hour screening visit and two 2.5-hour study visits. Study visits will... Read More
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
05/09/2024
Locations: University of Missouri, Columbia, Missouri
Conditions: Cerebrovascular Circulation
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Cardiopulmonary Monitoring in Lung Cancer Patients Receiving Combined Thoracic Radiotherapy and Immunotherapy
NCT06410300
Recruiting
The overall purpose of this study is to evaluate cardiopulmonary toxicity in patients with lung cancer (NSCLC or SCLC) undergoing combined thoracic radiotherapy ± chemotherapy and immunotherapy through timed monitoring and blood sample collection and to identify correlative biomarkers for predicting cardiopulmonary adverse events.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: University of Missouri - Ellis Fischel Cancer Center, Columbia, Missouri
Conditions: Lung Cancer
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Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis
NCT05327127
Recruiting
A study to investigate the use of combination therapy with two investigational products for the treatment of adult patients with Nonalcoholic steatohepatitis (NASH).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: GI Associates Research, LLC, Columbia, Missouri
Conditions: NASH
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Screening for Sacral Agenesis in Offspring of Mothers With Diabetes in Pregnancy
NCT05033275
Recruiting
Babies born to mothers with pregestational diabetes will be screened with parental consent for sacral agenesis
Gender:
All
Ages:
All
Trial Updated:
05/06/2024
Locations: MU, Columbia, Missouri
Conditions: Infant of Diabetic Mother, Sacral Agenesis
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tDCS and Metacognitive Strategy Training in Stroke
NCT05248178
Recruiting
Specific Aim 1: Complete pilot testing of study protocol in individuals with chronic stroke for feasibility evaluation and protocol refinement. Specific Aim 2: Estimate the preliminary effect of CO-OP+tDCS on activity performance in individuals with chronic stroke.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/06/2024
Locations: University of Missouri Occupational Therapy Department, Columbia, Missouri
Conditions: Chronic Stroke
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A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia
NCT05926765
Recruiting
This study will assess the efficacy and safety of bilateral intra-parotid administration of AAV2-hAQP1 in adults with Grade 2 or Grade 3 radiation-induced late xerostomia.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Missouri, Columbia, Missouri
Conditions: Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
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Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
NCT05219617
Recruiting
The primary objective is to evaluate the efficacy of carisbamate (YKP509) as adjunctive treatment in reducing the number of drop seizures (tonic, atonic, and tonic-clonic) compared with placebo in pediatric and adult subjects (age 4-55 years) diagnosed with Lennox Gastaut Syndrome (LGS).
Gender:
All
Ages:
Between 4 years and 55 years
Trial Updated:
05/03/2024
Locations: University of Missouri School of Medicine, Columbia, Missouri
Conditions: Seizures, Lennox Gastaut Syndrome
Register for Updates
ADAM17 and Vascular Function in Diabetes
NCT04557228
Recruiting
The objective of this project is to determine the extent to which administration of the dietary supplement phosphatidylserine (PS), a competitive inhibitor of ADAM17 sheddase activity, effects vascular function and insulin-stimulated leg blood flow in subjects with T2D.
Gender:
All
Ages:
Between 45 years and 64 years
Trial Updated:
05/03/2024
Locations: University of Missouri- NextGen Clinical Translational Science Unit, Columbia, Missouri
Conditions: Diabetes Mellitus, Type 2
Register for Updates