There are currently 19 clinical trials in Edison, New Jersey looking for participants to engage in research studies. Trials are conducted at various facilities, including John F. Kennedy Medical Center, JFK Medical Center and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Recruiting
This prospective longitudinal study will compare incidence rates of Medicare beneficiary surgical and minimally invasive intervention post index procedure, as well as harms associated with the MILD procedure, at 24 months post-treatment with MILD, tested against a control group of similar patients that have had a comparable procedure. This study will start with patients treated with a study procedure having an index date on or after January 1, 2017, and enrollment will continue until stopped by... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/20/2023
Locations: Ambulatory Surgical Center of New Jersey, LLC, Edison, New Jersey +2 locations
Conditions: Lumbar Spinal Stenosis
Assessment of CCM in HF With Higher Ejection Fraction
Recruiting
The AIM HIGHer Clinical Trial will evaluate the safety and efficacy of Cardiac Contractility Modulation (CCM) therapy in patients with heart failure with LVEF ≥40% and ≤60%.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/15/2023
Locations: Hackensack University Medical Center, Edison, New Jersey +1 locations
Conditions: Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction, Heart Failure With Moderately Reduced Ejection Fraction, Diastolic Heart Failure
A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting
Recruiting
This is an observational study in people with chronic kidney disease (CKD) and type 2 diabetes (T2D) who will be receiving finerenone. Kidneys filter extra water and waste out of the blood and make urine. CKD is a long-term, progressive, decrease in the kidneys' ability to filter the blood properly. In people with T2D, the body does not make enough of a hormone called insulin, or does not use insulin well enough, resulting in high blood sugar levels that can cause damage to the kidneys. As a re... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/15/2023
Locations: The EnLyv Clinics, Edison, New Jersey
Conditions: Chronic Kidney Disease, Type 2 Diabetes Mellitus
A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS)
Recruiting
This is an adaptive Phase 2/3 multicenter, double-blind, placebo-controlled, randomized, parallel, 3 arm study to evaluate the efficacy and safety of DA-1229 compared to placebo in patients with calcific aortic valve disease with mild to moderate aortic stenosis. There are 3 arms in this study to which patients will be randomized in a ratio of 1:1:1 to receive the DA-1229 or placebo orally once daily for a period of 104 weeks . the 3 arms are: placebo, DA-1229 5mg GroupDA-1229 10 mg Group. The... Read More
Gender:
All
Ages:
35 years and above
Trial Updated:
11/14/2023
Locations: Hackensack Meridian Health, Edison, New Jersey
Conditions: Calcific Aortic Valve Disease
A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma
Recruiting
The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma to evaluate improvements in lung function, asthma control, and quality of life. In addition, the study will further evaluate the safety and tolerability of dexpramipexole in participants with eosinophilic asthma.
Gender:
All
Ages:
Between 12 years and 99 years
Trial Updated:
11/13/2023
Locations: Research Site 40001-363, Edison, New Jersey
Conditions: Eosinophilic Asthma, Asthma; Eosinophilic, Asthma Attack
A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3)
Recruiting
The objective of this clinical study is to investigate the safety, tolerability, and efficacy of dexpramipexole in participants with inadequately controlled severe eosinophilic asthma.
Gender:
All
Ages:
Between 12 years and 99 years
Trial Updated:
11/13/2023
Locations: Research Site 30001-363, Edison, New Jersey
Conditions: Eosinophilic Asthma, Asthma; Eosinophilic, Asthma
Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM
Recruiting
To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM patients, compared to radiation therapy and temozolomide alone. In both arms, Optune® and maintenance temozolomide are continued following radiation therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/31/2023
Locations: JFK Neuroscience Institute, HMH JFK University Medical Center, Edison, New Jersey
Conditions: Glioblastoma Multiforme
Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in PGTC Seizures
Recruiting
This trial is intended to study the safety and effectiveness of an new anti-epileptic drug (AED) on Primary Generalized Tonic-Clonic (PGTC) Seizures. Eligible Subjects, adults and adolescents, will continue to take their usual AEDs and receive either cenobamate or placebo. Subjects will have a 50% chance or receiving cenobamate or placebo (sugar pill). Subjects will initially receive 12.5 mg of cenobamate or placebo (study drug) and increase the dose every two weeks until they reach a target dos... Read More
Gender:
All
Ages:
12 years and above
Trial Updated:
10/27/2023
Locations: JFK Medical Center- The Neuroscience Institute, Edison, New Jersey
Conditions: Primary Generalized Epilepsy
Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors
Recruiting
An open label, non-randomized study in pediatric patients with advanced high-grade gliomas and other solid tumors. The study will be performed in two phases: a dose escalation phase in up to 18 patients following a standard "3+3" design to establish dose-limiting toxicity (DLT) and a "safe" dose of LAM561 followed by an expanded safety cohort of up to 10 patients treated at the Maximum Tolerated Dose (MTD). If the MTD is well tolerated in the expanded safety cohort, that dose becomes the Recomm... Read More
Gender:
All
Ages:
18 years and below
Trial Updated:
09/27/2023
Locations: Hackensack Meridian Health, Inc, Edison, New Jersey
Conditions: High-grade Glioma, Solid Tumor, Unspecified, Child
Endovascular Therapy for Low NIHSS Ischemic Strokes
Recruiting
This study will test the hypothesis that patients presenting within 8 hours of onset with cerebral ischemia in the setting of proximal large vessel occlusions (LVO) and low baseline NIHSS scores (0-5) will have better 90-day clinical outcomes (mRS distribution) with immediate mechanical thrombectomy (iMT) compared to initial medical management (iMM).
Gender:
All
Ages:
18 years and above
Trial Updated:
09/06/2023
Locations: JFK Neurosciences Center, Edison, New Jersey
Conditions: Cerebral Ischemia
Safe Surveillance of PCI Under Mechanical Circulatory Support With the Saranas Early Bird Bleed Monitoring System
Recruiting
The objective of this study is to establish the safety of complex high-risk Percutaneous Coronary Intervention (PCI) using Mechanical Circulatory Support (MCS) and surveillance with the Saranas Early Bird Bleed Monitoring System (EBBMS).
Gender:
All
Ages:
18 years and above
Trial Updated:
07/05/2023
Locations: Hackensack Meridian Health, Edison, New Jersey
Conditions: Coronary Artery Disease
Cardiac Rehabilitation of Stroke Survivors (SRP-CROSS)
Recruiting
This study examines the effectiveness of the cardiac rehabilitation program for stroke patients. The study will examine if patients with stroke, who receive cardiac rehabilitation in addition to their standard of care treatments, demonstrate improved recovery of function. It will also examine if these patients have reduced hospital readmission, reduced rate of recurrent stroke, and mortality.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2023
Locations: Hackensack Meridian Health - JFK Johnson Rehabilitation Institute, Edison, New Jersey
Conditions: Stroke, Cerebrovascular Accident