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COVID19 Paid Clinical Trials in North Carolina
A listing of 29 COVID19 clinical trials in North Carolina actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 29
The state of North Carolina currently has 29 active clinical trials seeking participants for COVID19 research studies. These trials are conducted in various cities, including Durham, Winston-Salem, Charlotte and Chapel Hill.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Healthy Volunteer Trials
Recruiting
Healthy trials near you are looking for participants to help push medical research forward. Click through to learn more!
Conditions:
Healthy
Featured Trial
Chronic Cough Clinical Study
Recruiting
We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required.
Conditions:
Cough
Chronic Cough
Asthma
Allergic Asthma
Sinusitis
Featured Trial
Loss of Smell Study
Recruiting
Want your smell back?
A new study is enrolling people who've had a reduced sense of smell for at least six months due to a viral infection.
A new study is enrolling people who've had a reduced sense of smell for at least six months due to a viral infection.
Conditions:
Long Covid
Long COVID-19
COVID-19; Long COVID
COVID
Hyposmia
Featured Trial
COVID-19 Vaccination for Children
Recruiting
The purpose of this clinical trial is to evaluate a booster dose of mRNA-1273.815, Moderna’s investigational COVID-19 vaccine, to learn more about whether the investigational vaccine is safe when given as a booster that is the same dose as an initial COVID-19 vaccination.
Featured Trial
High blood pressure (Hypertension) Trials
Recruiting
High blood pressure (Hypertension) trials near you are looking for participants to help push medical research forward. Click through to learn more!
Conditions:
High blood pressure (Hypertension)
Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir)
Recruiting
Treatments are needed to improve outcomes among patients hospitalized for COVID-19, including direct-acting antiviral (DAA) agents to mitigate the pathology driven by ongoing viral replication. This trial will evaluate S-217622 (ensitrelvir), an anti-SARS-CoV2 3C-like protease inhibitor (PI) developed by Shionogi &; Co. Ltd.
The study design is a randomized, placebo-controlled, multi-center international clinical trial that will evaluate the clinical efficacy of ensitrelvir when given in additi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/12/2024
Locations: Duke University Hospital (Site 301-006), Durham, North Carolina +1 locations
Conditions: COVID-19
Reparixin add-on Therapy to Std Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia
Recruiting
Primary objective:
- To evaluate the efficacy of oral reparixin versus standard care alone in limiting disease progression in adult patients hospitalised for infectious pneumonia acquired in the community (CAP), including COVID-19.
Secondary objectives:
- To determine the effect of reparixin on several disease severity/progression measures including recovery, ventilatory free days and mortality.
Safety objectives:
- To evaluate the safety of oral reparixin versus placebo in the specific cli... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/10/2024
Locations: Duke University Hospital, Durham, North Carolina
Conditions: Infectious Pneumonia, Severe COVID-19
COVID-19 Vaccination Hesitancy in Adults With Sickle Cell Disease
Recruiting
The goal of this clinical trial is to test an COVID-19 vaccination information video in adults with sickle cell disease. The main questions it aims to answer are why are some adults with sickle cell disease hesitant to receive COVID-19 vaccination and whether a COVID-19 vaccination information video tailored for people with sickle cell disease will reduce vaccine hesitancy. Participants will complete a brief survey before and after watching a short video with information on vaccine safety, effic... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/06/2024
Locations: Duke Adult Sickle Cell Program, Durham, North Carolina
Conditions: Sickle Cell Disease, COVID-19 Vaccine, Vaccine Hesitancy
Conversations You Want About Corona Virus Disease (COVID-19)
Recruiting
Web-enabled virtual topical guide: develop virtual conversations for each concern and intensity level
Gender:
All
Ages:
18 years and above
Trial Updated:
06/04/2024
Locations: Wake Forest Health Sciences, Winston-Salem, North Carolina
Conditions: Covid19
EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
Recruiting
The purpose of this clinical trial is to learn about the safety, pharmacokinetics (pharmacokinetics helps us understand how the drug is changed and eliminated from your body after you take it), and efficacy (how well a study treatment works in the study) of the study medicine (called nirmatrelvir/ritonavir) for potential treatment of coronavirus disease 2019 (COVID-19).
The study medicine will be given to patients under 18 years of age with COVID-19 that are not hospitalized but are at risk for... Read More
Gender:
All
Ages:
Between 0 years and 17 years
Trial Updated:
06/03/2024
Locations: Clinical and Translational Research Center, Chapel Hill, North Carolina +7 locations
Conditions: COVID-19
A Study to Learn About the Study Medicine (Nirmatrelvir Plus Ritonavir) in Pregnant Women With COVID-19
Recruiting
The purpose of this clinical trial is to learn about how study medicine (Paxlovid, which contains nirmatrelvir and ritonavir) is changed and eliminated from the body, as well as its safety, and the extent to which side effects can be tolerated for treatment of pregnant women with mild or moderate COVID-19 compared to non-pregnant women with mild or moderate COVID-19.
This study is seeking participants who:
are expecting a healthy baby and are in their second or third trimester pregnancy and ha... Read More
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
06/03/2024
Locations: Unified Women's Clinical Research (Administrative Office), Winston-Salem, North Carolina +1 locations
Conditions: COVID-19
Strategies and Treatments for Respiratory Infections &Amp; Viral Emergencies (STRIVE): Immune Modulation Strategy Trial
Recruiting
COVID-19 can trigger a dysregulated immune response, and previous studies have shown that immune modulation can improve outcomes in hospitalized patients. This trial is designed to determine whether intensification of immune modulation early in the course of the disease (while patients are on low flow oxygen) with abatacept (active arm) combined with standard of care (SOC) improves recovery as compared with placebo + SOC (placebo arm). For both groups, intensification of immunomodulation will be... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Duke University Hospital (Site 301-006), Durham, North Carolina +1 locations
Conditions: COVID-19
Duke COVID-19 Shared Data and Specimen Repository
Recruiting
The purpose of this data repository is to provide a secure and centralized storage location and resource for the collection of essential data and medical specimens, across COVID-19 related protocols at Duke.
Gender:
All
Ages:
All
Trial Updated:
05/20/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: COVID-19
A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children
Recruiting
The purpose of this clinical trial is to learn about the safety, extent of the side effects, and immune responses of the study vaccine (called variant-adapted BNT162b2 RNA-based vaccine) in healthy children. The trial is divided into 5 individual studies or substudies based on age group and prior history of COVID-19 vaccinations. All participants in each of the 5 sub-studies will receive study vaccine as a shot depending on what group they are in.
Substudy A design: Phase 1 includes participant... Read More
Gender:
All
Ages:
Between 6 months and 11 years
Trial Updated:
05/13/2024
Locations: Atrium Health - Carolinas Medical Center, Charlotte, North Carolina +1 locations
Conditions: SARS-CoV-2 Virus, Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19
Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction
Recruiting
The goal of this pilot study is to assess the feasibility and impact of using sodium citrate nasal spray as an adjunct to olfactory retraining in participants with long-term post-COVID-19 olfactory dysfunction.
The main questions it aims to answer are:
Is sodium citrate nasal spray in addition to smell retraining feasible for participants to use in terms of participant need/desire, adherence, and adverse events?
Does sodium citrate nasal spray in addition to smell retraining further improve sm... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Long Haul COVID-19, Post-Acute COVID-19 Syndrome, Anosmia, Olfaction Disorders
REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19
Recruiting
Multicenter, prospective, randomized controlled trial providing mobile health supported physical rehabilitation to 120 patients who have been critically ill with COVID-19 and who complete at least one exercise session.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/02/2024
Locations: Duke University Health System, Durham, North Carolina
Conditions: COVID-19, Critical Illness, ICU Acquired Weakness, PICS, Cardiorespiratory Fitness
COVID-19 Testing and Vaccination Among Spanish Speakers
Recruiting
Latinx communities are disproportionately affected by the COVID-19 pandemic, with Spanish-speaking Latinx communities carrying even heavier burdens of infection, hospitalization, and mortality. Major barriers to COVID-19 testing and vaccination exist, and a profound need remains to understand and address the social, ethical, and behavioral implications (SEBI) of COVID-19 testing and vaccination within Latinx communities. Our community-academic partnership proposes a rigorous mixed-methods, commu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2024
Locations: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Conditions: COVID-19, Vaccinations
1 - 12 of 29