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Osteoarthritis Clinical Trials in Cleveland, OH
A listing of 7 Osteoarthritis clinical trials in Cleveland, OH actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 7 of 7
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The city of Cleveland, Ohio, currently has 7 active clinical trials seeking participants for Osteoarthritis research studies.
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Conditions:
High Blood Pressure
High Blood Pressure (& [Essential Hypertension])
High Blood Pressure (Hypertension).
Hypertension
Essential Hypertension
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Conditions:
Healthy
Healthy Volunteer Study
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📋 5 providers ranked by true monthly cost
💵 Options starting as low as $149/month
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🔒 Includes cancellation policy warnings so you don't get stuck
Conditions:
Weight Loss
Morbid Obesity
Featured Trial
Rheumatoid Arthritis (RA) Clinical Research Study
Recruiting
The Ntrust-2 study is a clinical research study evaluating an investigational cell therapy, called NKX019, in adults living with rheumatoid arthritis (RA).
The Ntrust-2 study
The Ntrust-2 study is part of a broad effort of the global research community to develop more treatment options for people living with rheumatoid arthritis.
What is NKX019?
NKX019 is an investigational cell therapy being studied for rheumatoid arthritis (RA). It is designed to target and remove the cells that may trigger harmful antibodies, which attack the body’s own tissues in these conditions.
Who can join this study?
You may be eligible to participate in this study if you:
- Are 18 to 75 years old
- Have been diagnosed with rheumatoid arthritis (RA)
- Have received prior autoimmune disease treatments that may have not worked well for you
Compensation
If you are eligible and choose to participate, you will receive NKX019 and health assessments from a team with expertise in caring for people living with autoimmune disease. Costs for travel, lodging, childcare, and meals will be covered when you and your care partner go to the study clinic. Compensation for study participants and your care partner may also be available.
The Ntrust-2 study
The Ntrust-2 study is part of a broad effort of the global research community to develop more treatment options for people living with rheumatoid arthritis.
What is NKX019?
NKX019 is an investigational cell therapy being studied for rheumatoid arthritis (RA). It is designed to target and remove the cells that may trigger harmful antibodies, which attack the body’s own tissues in these conditions.
Who can join this study?
You may be eligible to participate in this study if you:
- Are 18 to 75 years old
- Have been diagnosed with rheumatoid arthritis (RA)
- Have received prior autoimmune disease treatments that may have not worked well for you
Compensation
If you are eligible and choose to participate, you will receive NKX019 and health assessments from a team with expertise in caring for people living with autoimmune disease. Costs for travel, lodging, childcare, and meals will be covered when you and your care partner go to the study clinic. Compensation for study participants and your care partner may also be available.
Conditions:
Rheumatoid
Rheumatoid Arthritis
Arthritis
Rheumatoid
Rheumatoid Arthritis (RA)
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✅ Providers starting at $242/month
✅ Only accredited, licensed compounding pharmacies
✅ Ranked by real pricing, not marketing promises
✅ Includes patient reviews & hidden fee warnings
✅ Updated for 2026
Conditions:
Overweight
Overweight and Obesity
Featured Trial
Obesity (BMI >= 30) Clinical Study
Recruiting
A clinical study for people that suffer with Obesity (BMI >= 30)
Conditions:
Obesity (BMI >= 30)
Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study
Recruiting
The goal of the Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study is to collect safety and performance data on the commercially available Shoulder iD™ Primary Reversed Glenoid device. The study will learn about standard device use in adult patients who have a functional deltoid muscle and massive and non-repairable rotator cuff tear. The main questions it aims to answer are:
* What is the average improvement in patient-reported shoulder function after 2 years when compared to before... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/22/2025
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Rotator Cuff Tears, Rheumatoid Arthritis Shoulder, Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus, Fracture, Humeral, Traumatic Arthritis of Right Shoulder Region (Diagnosis), Shoulder Deformity
Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes
Recruiting
This study is a randomized controlled trial to assess whether the implementation of a TKA Personalized Outcome Prediction Tool to set expectation, in addition to targeted interventions to address patients with poor baseline mental health and poor physical function, improves satisfaction at 1-year (when compared to standard of care).
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/14/2025
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Knee Osteoarthritis, Knee Arthropathy, Surgery
Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry
Recruiting
Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health. Towards this goal, extensive efforts are ongoing to develop quantitative MRI for cartilage matrix analysis. MR T1ρ and T2 relaxation times have shown to be promising imaging biomarkers for early cartilage degeneration and prediction of disease progression. However, many c... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
05/06/2025
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Bone Diseases, Infectious, Musculoskeletal Diseases, Joint Diseases, Osteoarthritis, ACL Tear, Cartilage Degeneration
Preventing Injured Knees From osteoArthritis: Severity Outcomes
Recruiting
This study is being done to find out if metformin is effective at reducing pain by delaying the onset of post-traumatic osteoarthritis (PTOA) after anterior cruciate ligament (ACL) reconstruction. This research study will compare metformin to placebo. The placebo tablet looks exactly like metformin, but contains no metformin. Placebos are used in research studies to see if the results are due to the study drug or due to other reasons.
Metformin is approved by the U.S. Food and Drug Administrati... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
04/25/2025
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Osteoarthritis, Knee, Post-traumatic Osteoarthritis, ACL Tear
A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension
Recruiting
The objectives of this prospective observational cohort study are to evaluate the safety, reliability, reproducibility, and accuracy of the Canary canturioTM te post-TKA.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Knee Osteoarthritis
Persona Revision Knee System Outcomes
Recruiting
The study will evaluate the performance, clinical benefits and safety of the Persona Revision Knee System in patients who have received primary or revision total knee arthroplasty (TKA) treatment. This will be done using a multicenter, single-arm, consecutive series, retrospective cohort study with prospective follow-up.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: The Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Arthroplasty Complications, Infection, Knee Disease, Knee Osteoarthritis
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
Recruiting
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
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