The city of Cleveland, Ohio, currently has 23 active clinical trials seeking participants for Pain research studies.
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
NCT05787821
Recruiting
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
Gender:
All
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
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Preoperative (Pre-amputation) Cryoanalgesia to Improve Post-amputation Phantom Limb Pain
NCT06284109
Recruiting
Investigators will evaluate preamputation cryoanalgesia on pain, mobility, opioid use and general physical and emotional disability using a pilot randomized trial design, to explore the amount and variability of improvement on those outcomes and to investigate the potentiality of conducting a future larger randomized controlled trial, which the investigators will assess quantitatively the benefits of cryoanalgesia.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Postoperative Pain
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Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Reduction During Intrauterine Device (IUD) Insertion in Outpatient Gynecology
NCT06335823
Recruiting
Pain with intrauterine device (IUD) insertion is very common and there are few options for patients to help reduce this pain. Transcutaneous electric nerve stimulators (TENS) are a non-invasive procedure that may help reduce the pain with IUD insertions. The investigators hope that the information gleaned from this study will result in pain control options for future patients who desire an IUD placement.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
06/18/2024
Locations: University Hospitals, Cleveland, Ohio
Conditions: IUD Insertion Pain
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No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair
NCT05929937
Recruiting
The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investigators believe there will be no significant difference in postoperative readmission for pain quality of life at 30 days in either group.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: University Hospitals, Cleveland, Ohio +1 locations
Conditions: Postoperative Pain, Inguinal Hernia
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Patient Retrospective Outcomes (PRO)
NCT01550575
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: University Hospitals of Cleveland, Cleveland, Ohio
Conditions: Chronic Pain
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RELIEF - A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
NCT01719055
Recruiting
To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use - and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice
Gender:
All
Ages:
18 years and above
Trial Updated:
06/06/2024
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Pain
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Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)
NCT05688410
Recruiting
This work will involve conducting a randomized trial that will evaluate preliminary efficacy of "assisted" rate cycling, voluntary rate cycling and psychotherapy for pain individually and in combination as adjunctive treatments on cravings (primary outcome) in adults with an opioid use disorder. The investigators will also evaluate the effects of "assisted" rate cycling, voluntary rate cycling and I-STOP on secondary outcomes including depression, anxiety and sleep.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/03/2024
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Opioid Use Disorder, Pain
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Study of V117957 in Interstitial Cystitis/Bladder Pain Syndrome
NCT06285214
Recruiting
The purpose of this study is to evaluate the safety, tolerability and efficacy of V117957 in subjects with interstitial cystitis/bladder pain syndrome, compared to placebo.
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/31/2024
Locations: MetroHealth System, Cleveland, Ohio
Conditions: Interstitial Cystitis/Bladder Pain Syndrome
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A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome
NCT05740007
Recruiting
The aim of this study is to assess whether IW-3300 is safe and works for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS). The main question the study aims to answer is whether IW-3300 helps bladder pain and other symptoms (for example, bladder burning, pressure and discomfort). Subjects will be assigned to receive either the study drug or placebo by chance.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/30/2024
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
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Optimization of NIBS for Treatment of Addiction
NCT04379115
Recruiting
The purpose of this study is to assess the effects of transcranial Direct Current Stimulation (tDCS) applied in conjunction with Transcranial Ultrasound (TUS) for the treatment of addiction in opiate use disorder with chronic pain. The investigators hypothesize that there will be a decrease in drug use and improved psychosocial assessments with active stimulation, when compared to sham stimulation.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/30/2024
Locations: University Hospitals Cleveland Medical Center/ Dahms Clinical Research Unit, Cleveland, Ohio
Conditions: Opioid-use Disorder, Chronic Pain
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Music Therapy in Patients Undergoing Pancreatic Surgery (MUSIC PUPS)
NCT06123013
Recruiting
Pilot single arm non-randomized trial to determine the feasibility and acceptability of: 1) a tailored music-assisted relaxation and imagery intervention; 2) biological sample collection; and 3) mobile device patient-reported outcome (MDPRO) collection in adults hospitalized for pancreatic surgery experiencing acute pain.
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
04/18/2024
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Whipple Procedure, Distal Pancreatectomy, Acute Pain
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Precise and Objective Identification of Bertolotti Syndrome Using Novel Kinematic Biomarkers
NCT06225583
Recruiting
The purpose of this study is to collect lumbar rotations, velocity, and accelerations, along with pain scores using a novel dynamic VAS device, from twenty (20) Bertolotti Syndrome patients and twenty (20) non-Bertolotti low back pain patients during range-of-motion tasks. The assessments will be analyzed to determine the differences in kinematics and continuous pain scores between Bertolotti patients and non-Bertolotti low back pain patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/08/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Bertolotti's Syndrome, Lower Back Pain
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