The state of Oklahoma currently has 8 active clinical trials seeking participants for Osteoarthritis research studies. These trials are conducted in various cities, including Oklahoma City, Tulsa, Norman and Edmond.
A Study to Determine the Safety and Efficacy of TG-C in Subjects With Kellgren and Lawrence Grade 2 or 3 OA of the Knee
NCT03203330
Recruiting
A randomized, double-blind, placebo-controlled, multi-center, phase 3 study to determine the safety and efficacy of TG-C in subjects with Kellgren and Lawrence Grade 2 or 3 Osteoarthritis of the Knee, Osteoarthritis Research Society International (OARSI) medial joint space narrowing (JSN) Grade 1 or 2 of the knee joint. TG-C is to be administered by a single intra-articular injection to the damaged joint area via ultrasound guidance. Patients will be followed for 24 months for safety and efficac... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
04/10/2024
Locations: Yogesh Mittal, Tulsa, Oklahoma
Conditions: Degenerative Osteoarthritis
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Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis
NCT06121882
Recruiting
The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus saline injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis. Participants will receive an injection of MFat or saline.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/10/2024
Locations: The Orthopedic Center - NextStage Clinical Research - Tulsa, Tulsa, Oklahoma
Conditions: Knee Osteoarthritis, Osteo Arthritis Knee
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A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
NCT05986292
Recruiting
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/03/2024
Locations: DelRicht Research, Tulsa, Oklahoma
Conditions: Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
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GAE Using Embosphere Microspheres vs Corticosteroid Injections for Treatment of Symptomatic Knee OA
NCT05818150
Recruiting
This multicenter, prospective, interventional trial is designed to assess the outcome of subjects with symptomatic knee osteoarthritis (OA) that are randomized to treatment with either genicular artery embolization (GAE) using Embosphere Microspheres or steroid injection over a period of 24 months.
Gender:
All
Ages:
21 years and above
Trial Updated:
03/15/2024
Locations: Cardiovascular Health Clinic, Oklahoma City, Oklahoma
Conditions: Knee Osteoarthritis
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Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System
NCT04770870
Recruiting
The H3 TAR Prosthesis was approved by FDA (P160036) on June 4, 2019. Continued approval of the premarket approval application (PMA) is contingent upon the submission of periodic reports (Annual Report), required under 21 CFR 814.84. In order to provide continued reasonable assurance of the safety and effectiveness of the PMA device, data from this post-approval study must be submitted to FDA in a PMA Post-Approval Study Report per the requirements set forth in the approval.
Gender:
All
Ages:
21 years and above
Trial Updated:
03/07/2024
Locations: Dept. of Orthopedic Surgery and Rehabilitation, University of Oklahoma, Oklahoma City, Oklahoma
Conditions: Osteoarthritis Ankle, Post-Traumatic Osteoarthritis of Ankle, Osteoarthritis of Ankle Secondary to Inflammatory Arthritis (Disorder)
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Innovations in Genicular Outcomes Registry
NCT05495334
Recruiting
The registry will capture prospective data on patients receiving pain management for chronic pain due to knee osteoarthritis (OA) or pain optimization for knee arthroplasty due to knee OA. The OA pain therapies may include cryo nerve block, radiofrequency ablation (RFA), intra-articular (IA) corticosteroids, viscosupplementation, opioids, and others (e.g., non-steroidal anti-inflammatory drugs [NSAIDs]).
Gender:
All
Ages:
All
Trial Updated:
03/01/2024
Locations: Oklahoma Surgical Hospital, Tulsa, Oklahoma
Conditions: Knee Osteoarthritis
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A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee
NCT06000410
Recruiting
This study is being conducted to evaluate the efficacy and safety of ASA compared to placebo in the management of osteoarthritis (OA) symptoms of the knee.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/01/2024
Locations: Conrad Clinical Research, Edmond, Oklahoma +1 locations
Conditions: Knee Osteoarthritis
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Physica System Total Knee Replacement Registry Study
NCT03048201
Recruiting
The primary objective of this study is to obtain long-term implant survivorship (out to 10 years) and to assess clinical, patient-reported outcome measures, and radiographic data for the commercially available Physica system. For ancillary arm, from baseline to 5-year follow-up.
Gender:
All
Ages:
22 years and above
Trial Updated:
03/17/2023
Locations: Joint Reconstructive Specialist, Oklahoma City, Oklahoma
Conditions: Osteoarthritis, Knee, Traumatic Arthritis, Avascular Necrosis, Degenerative Joint Disease of Knee, Rheumatoid Arthritis, Deformity of Knee
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