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Diabetes Clinical Trials in Pittsburgh, PA
A listing of 29 Diabetes clinical trials in Pittsburgh, PA actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
13 - 24 of 29
The city of Pittsburgh, Pennsylvania, currently has 29 active clinical trials seeking participants for Diabetes research studies.
Featured Trial
55+ Obesity and Cardiovascular Disease Clinical Study
Recruiting
Diagnosed with cardiovascular disease? Join our local overweight with cardiovascular issues clinical trial. Every 34 seconds, someone in the US dies of cardiovascular disease. Wonder how you could help? If you’re eligible for our CVD clinical trial, you could receive up to $1500.
Conditions:
Obesity
Overweight and Obesity
Cardiovascular Disease
Cardiovascular Diseases
Cardiovascular Health
Featured Trial
Type 2 Diabetes Clinical Trials
Recruiting
Type 2 Diabetes trials near you are looking for participants to help push medical research forward. Click through to learn more!
Conditions:
Type 2 Diabetes
Diabetes Mellitus Type 2 in Obese
Featured Trial
Major Depressive Disorder Clinical Study
Recruiting
Is depression weighing you down? Local major depressive disorder clinical studies are now enrolling participants in the area. Participating in research studies helps contribute to the advancement of future medicine and treatment options. There is no obligation to take part and health insurance is not required.
Conditions:
Major Depressive Disorder
Major Depression
Major Depressive Episode
Major Depressive Disorder (MDD)
Major Depressive Disorders
Featured Trial
Hyperacusis Activities Treatment-Online Study
Recruiting
Are you experiencing hyperacusis? If so, we are recruiting adults with hyperacusis to complete a clinical trial supported by the National Institutes of Health. The study involves participating in a remote counseling program and sound therapy trial for hyperacusis, Hyperacusis Activities Treatment-Online.
Conditions:
Hyperacusis
Tinnitus
Hearing Loss
Behavioral Economics for Activity Motivation in Adolescents (BEAM)
Recruiting
There is an urgent need to engineer targeted physical activity interventions that are effective and scalable for obese adolescents and young adults (AYA) with type 2 diabetes (T2D), who often have very low levels of physical activity. The BEAM Trial is a proposed mobile health (mHealth) intervention that uses behavioral economic-informed financial incentives and text messaging to promote physical activity in AYA with T2D and prediabetes.
Gender:
All
Ages:
Between 13 years and 22 years
Trial Updated:
04/03/2024
Locations: UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Type 2 Diabetes, PreDiabetes, Insulin Resistance, Polycystic Ovary Syndrome
Pilot Brief Communal Coping Intervention for Adults With Type 1 Diabetes
Recruiting
We plan to develop a communal coping intervention aimed at instilling a shared appraisal of diabetes and increasing patient-partner collaboration. To that end, we will pilot the first randomized clinical trial of a brief communal coping intervention among couples in which one person has T1D
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: Carnegie Mellon University, Pittsburgh, Pennsylvania
Conditions: Diabetes Mellitus, Type 1
Rituximab-pvvr and Abatacept vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes
Recruiting
The study is a two-arm, multicenter, double-blinded clinical trial testing sequential therapy with rituximab-pvvr followed by abatacept versus rituximab-pvvr alone in new onset T1D. The primary objective is to test whether the C-peptide response to a 2-hour mixed meal tolerance test, will be improved in participants with new onset T1D who are treated with Abatacept after Rituximab-pvvr compared to those treated with Rituximab-pvvr and placebo 24 months after enrollment.
Gender:
All
Ages:
Between 8 years and 45 years
Trial Updated:
03/13/2024
Locations: University of Pittsburg, Pittsburgh, Pennsylvania
Conditions: Type 1 Diabetes Mellitus
A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk
Recruiting
The main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type 2 diabetes and obesity or overweight at increased cardiovascular risk. The study will last approximately 2 years may include up to 27 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/12/2024
Locations: Preferred Primary Care Physicians, Preferred Clinical Research-St. Clair, Pittsburgh, Pennsylvania
Conditions: Type 2 Diabetes, Obesity, Overweight or Obesity, Overweight, Cardiovascular Diseases, Chronic Kidney Disease
Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes
Recruiting
This study is being done to study how exenatide, an FDA-approved drug that lowers blood sugar in non-pregnant patients with type II diabetes, works in pregnant women. To do this, the investigators will study the drug's pharmacokinetics (what the body does to the drug; specifically, how quickly your body breaks down and excretes exenatide) and pharmacodynamics (what the drug does to the body; specifically, how effectively exenatide helps the participants' pancreas secrete insulin and how well it... Read More
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
03/06/2024
Locations: Magee Womens Hospital of UPMC, Pittsburgh, Pennsylvania
Conditions: Gestational Diabetes
The Metabolic Effects of Intermittent Fasting
Recruiting
Caloric restriction has beneficial metabolic effects in humans including weight loss and improvement in blood pressure and lipid levels. Intermittent fasting has emerged as a popular alternative to caloric restriction as it does not require daily adherence to a dietary protocol, but whether the benefits of fasting protocols are dependent on weight loss is not known. In this study, the investigators will explore the metabolic effects of fasting and evaluate whether these effects, including negati... Read More
Gender:
All
Ages:
Between 25 years and 45 years
Trial Updated:
03/01/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Normal and Overweight Individuals at High-risk of Diabetes
Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
Recruiting
A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100 days of diagnosis.
Gender:
All
Ages:
Between 12 years and 35 years
Trial Updated:
02/14/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Diabetes Mellitus, Type 1
Gamification of Pediatric Diabetes Education
Recruiting
The goal of this study is to evaluate the impact of a mobile app video game called Digital Vaccine for Type 1 Diabetes (DVx-T1D)™, proposed as a low-risk, non-invasive, digital therapeutic candidate for behavior change in children 6 to 12 years of age with Type 1 Diabetes (T1D).
We hypothesize that adoption of DVx-T1D™ by T1D patients will positively influence healthy dietary and physical activity behaviors by providing nutrition and lifestyle education through a playful, Artificial Intelligenc... Read More
Gender:
All
Ages:
Between 6 years and 12 years
Trial Updated:
02/12/2024
Locations: UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Diabetes Mellitus, Type 1, Behavior, Health
TrialNet Pathway to Prevention of T1D
Recruiting
Rationale:
The accrual of data from the laboratory and from epidemiologic and prevention trials has improved the understanding of the etiology and pathogenesis of type 1 diabetes mellitus (T1DM). Genetic and immunologic factors play a key role in the development of T1DM, and characterization of the early metabolic abnormalities in T1DM is steadily increasing. However, information regarding the natural history of T1DM remains incomplete. The TrialNet Natural History Study of the Development of T... Read More
Gender:
All
Ages:
Between 30 months and 45 years
Trial Updated:
12/20/2023
Locations: Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania
Conditions: Diabetes Mellitus, Type 1
STOP-T1D Low-Dose (ATG)
Recruiting
A multi-center, placebo-controlled, double blind, 2:1 randomized control clinical trial testing low-dose ATG vs. placebo in subjects with a 2 year 50% risk of progression to stage 3 T1D.
Gender:
All
Ages:
Between 12 years and 34 years
Trial Updated:
12/14/2023
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Diabetes Mellitus, Type 1
Expanding the Family Check-Up in Early Childhood to Promote Cardiovascular Health of Mothers and Young Children
Recruiting
This randomized-controlled pilot study will examine the implementation of a cardiovascular health intervention on postpartum mothers and infants. The investigators will adapt a cardiovascular health intervention into an evidence-based home visiting program, Family Check-Up to create Family Check-Up Heart. Through a Type 1 hybrid effectiveness implementation design, the pilot study will test the feasibility and effectiveness of Family Check-Up Heart (Family Check-Up Heart, n=100; Family Check-Up,... Read More
Gender:
All
Ages:
All
Trial Updated:
12/12/2023
Locations: Healthy Start, Inc., Pittsburgh, Pennsylvania +2 locations
Conditions: Obesity, Maternal, Hypertension in Pregnancy, Hypertension, Pregnancy-Induced, Diabetes, Overweight
A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes
Recruiting
This study will evaluate the safety, tolerability and efficacy of VX-880 infusion in participants with Type 1 diabetes mellitus (T1D) and impaired awareness of hypoglycemia (IAH) and severe hypoglycemia.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
10/30/2023
Locations: University of Pittsburgh Medical Center Montefiore, Pittsburgh, Pennsylvania
Conditions: Diabetes Mellitus, Type 1, Impaired Hypoglycemic Awareness, Severe Hypoglycemia
13 - 24 of 29