There are currently 168 clinical trials in Columbia, South Carolina looking for participants to engage in research studies. Trials are conducted at various facilities, including University of South Carolina, Prisma Health Richland Hospital, GSK Investigational Site and Palmetto Health South Carolina Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students
Recruiting
This study will assess how different types of training and support influence the way that school staff understand, and respond to, the mental and behavioral health needs of middle school students. Researchers will work with middle schools using a developed screening system (called the Early Identification System; EIS) and compare how staff and student outcomes change when schools receive two different types of training and support: 1) standard onboarding/training versus 2) participating in profe... Read More
Gender:
ALL
Ages:
Between 10 years and 99 years
Trial Updated:
10/11/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Mental Health Issue
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Recruiting
The main aim is to evaluate the safety and tolerability of TAK-861 on participants with type 1 narcolepsy, who were exposed to previously tested doses of TAK-861.
Gender:
ALL
Ages:
Between 16 years and 70 years
Trial Updated:
09/24/2024
Locations: Bogan Sleep Consultants, LLC, Columbia, South Carolina
Conditions: Narcolepsy Type 1
A Post-Market Study for Long-Term Effectiveness and Safety of the NTX100 for RLS
Recruiting
Multi-center post-market, observational study to assess the long-term effectiveness and safety of the NTX100 TOMAC System for patients with Restless Legs Syndrome.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
09/24/2024
Locations: Bogan Sleep Consultants, LLC, Columbia, South Carolina
Conditions: Restless Legs Syndrome
Pulse Endovascular ReperFUSION for Acute Ischemic Stroke
Recruiting
Prospective, multi-center, single-arm early feasibility study enrolling a minimum of 15 subjects at up to a minimum of 3 active investigational sites in the United States. The subjects must be diagnosed with acute ischemic stroke (AIS), must be post-mechanical thrombectomy, will have had intravenous thrombolytics, and have a visible MCA, ACA or PCA occlusive clot on initial angiographic imaging. Each subject will receive the Pulse NanoMED procedure after attempted neurovascular therapy to achi... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
08/26/2024
Locations: University of South Carolina - Prisma, Columbia, South Carolina
Conditions: Acute Ischemic Stroke AIS, Cerebral Arterial Disease
ABTECT - Maintenance
Recruiting
This is a multicenter, randomized, placebo-controlled study to evaluate the long-term efficacy and safety of ABX464 50mg and 25mg administered once daily (QD) as maintenance therapy in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhi... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
08/06/2024
Locations: Columbia Digestive Health Research, Columbia, South Carolina
Conditions: Ulcerative Colitis
Usability of the Adapted Rower for People With Spinal Cord Injury
Recruiting
The goal of this clinical trial is to examine usability of a locally built adaptive rower for people with spinal cord injury using an established and tested design. The main questions it aims to answer are: 1. What exercise intensity of activity do users achieve on the rower for steady state and interval rowing plans? 2. What assistance is required for setup and usage of the adaptive rower? 3. What do users think about the ease of use and what is their satisfaction with the adaptive rower? Pa... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/02/2024
Locations: Public Health Research Center, Columbia, South Carolina
Conditions: Spinal Cord Injuries
Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis
Recruiting
The goal of this clinical trial is to learn about INS018_055 in adults with Idiopathic Pulmonary Fibrosis (IPF). The primary objective is to evaluate the safety and tolerability of INS018_055 orally administered for up to 12 weeks in adult subjects with IPF compared to placebo.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
07/25/2024
Locations: Bogan Sleep Consultants, LLC, Columbia, South Carolina
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
ABTECT-1 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -1
Recruiting
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhibitors, anti-integrin... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
07/25/2024
Locations: Columbia Digestive Health Research, Columbia, South Carolina
Conditions: Ulcerative Colitis
Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents
Recruiting
The goal of this clinical trial is to investigate how the friendship experiences of maltreated (i.e., abused and/or neglected) and non-maltreated adolescents differentially influence their risk for adverse outcomes. The main questions it aims to answer are: 1. How do the friendships of maltreated adolescents differ from those of non-maltreated adolescents? 2. Which friendship experiences influence the associations between maltreatment and ability to regulate stress, as well as future mental hea... Read More
Gender:
ALL
Ages:
Between 13 years and 17 years
Trial Updated:
07/12/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Child Maltreatment, Interpersonal Relations, Victimisation, Psychopathology, Electrocardiography
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Recruiting
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Gender:
ALL
Ages:
75 years and above
Trial Updated:
06/14/2024
Locations: Columbia VA Health Care/Dorn VA Medical Center, Columbia, South Carolina
Conditions: Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
Family-Based Prevention With Black and Latinx Children
Recruiting
The main objective of this project is to test whether providing parenting support, with an added emphasis on ethnic-racial socialization and healthy lifestyle behaviors, improves the social-emotional functioning and healthy lifestyle behaviors of Black and Latinx children.
Gender:
ALL
Ages:
Between 3 years and 6 years
Trial Updated:
06/13/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Child Behavior, Health Behavior
HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry
Recruiting
The purpose of the HF2 (Hemodynamic Frontiers in Heart Failure) registry is to collect relevant patient-level demographic, clinical, laboratory, and hemodynamic data from patients implanted with pulmonary artery pressure sensor at participating centers to advance scientific knowledge about ambulatory hemodynamics monitoring and HF (Heart Failure) therapies. The data collected will be used for retrospective studies, quality improvement, identifying research cohorts, and member-initiated research.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
05/21/2024
Locations: Prisma Health, Columbia, South Carolina
Conditions: Heart Failure