There are currently 166 clinical trials in Columbia, South Carolina looking for participants to engage in research studies. Trials are conducted at various facilities, including University of South Carolina, Prisma Health Richland Hospital, GSK Investigational Site and Palmetto Health South Carolina Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
NCT00904241
Recruiting
This research trial studies biomarkers in tumor tissue samples from patients with newly diagnosed neuroblastoma or ganglioneuroblastoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
Gender:
All
Ages:
30 years and below
Trial Updated:
04/12/2024
Locations: Prisma Health Richland Hospital, Columbia, South Carolina
Conditions: Ganglioneuroblastoma, Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma, Regional Neuroblastoma, Stage 4 Neuroblastoma, Stage 4S Neuroblastoma
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Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
NCT00736749
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
All
Ages:
All
Trial Updated:
04/10/2024
Locations: Prisma Health Richland Hospital, Columbia, South Carolina
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
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LOWER: Lomitapide Observational Worldwide Evaluation Registry
NCT02135705
Recruiting
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Gender:
All
Ages:
All
Trial Updated:
03/11/2024
Locations: Palmetto Health, Columbia, South Carolina
Conditions: Homozygous Familial Hypercholesterolemia
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Healthy Kids Beyond the Bell: Investigating the Impact of After-School and Summer Programs
NCT05880901
Recruiting
Nearly one in five children are obese, and disparities in overweight and obesity between children from low- and middle-to-high-income households persist despite a multitude of school-based interventions. The structured days hypothesis posits that structure within a school day plays a protective role for children against obesogenic behaviors, and, ultimately, prevents the occurrence of excessive weight gain, thus, past school-based efforts are misplaced. This study will provide access to healthy... Read More
Gender:
All
Ages:
Between 5 years and 12 years
Trial Updated:
03/09/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Health Status Disparities, Pediatric Obesity, Ethnic Group, Socioeconomic Factors
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Determining the Optimal Amount of Structured Environments for Healthy Kids
NCT06158594
Recruiting
Studies show that virtually all increases in children's (5-12yrs) BMI occur during the summer, no matter children's' weight status (i.e., normal weight, overweight, or obese) at summer entry. Recent preliminary studies show that children engage in healthier behaviors on days that they attend summer day camps, and that BMI gain does not accelerate for these children. The proposed randomized dose-response study will identify the dose-response relationship between amount of summer programming and s... Read More
Gender:
All
Ages:
Between 5 years and 12 years
Trial Updated:
03/09/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Health Status Disparities, Pediatric Obesity, Ethnic Groups, Socioeconomic Factors
Register for Updates
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
NCT01574053
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Huntington's Disease
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Parent Intervention to Improve Child Sleep
NCT06038591
Recruiting
In this study, the investigators pilot tested a parenting intervention to improve young children's sleep in families with low income. Families were randomized to an intervention or wait-list control group. The investigators hypothesized the intervention would be feasible and acceptable to enrolled families.
Gender:
All
Ages:
Between 2 years and 4 years
Trial Updated:
01/31/2024
Locations: South Carolina early childhood support state agencies, Columbia, South Carolina
Conditions: Sleep
Register for Updates
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
NCT05338697
Recruiting
VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, transmagnetic stimulation (TMS), and MRI measures in the acute stroke time window.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Prisma Health Richland Hospital, Columbia, South Carolina
Conditions: Stroke, Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic
Register for Updates
In-Office Clinical Study of the Solo+ TTD
NCT05741333
Recruiting
The objective of this study is to evaluate the safety and effectiveness of the Solo+ Tympanostomy Tube Device (Solo+ TTD) for the placement of tympanostomy tubes in paediatric patients undergoing a tympanostomy procedure.
Gender:
All
Ages:
Between 6 months and 13 years
Trial Updated:
01/23/2024
Locations: South Carolina ENT, Columbia, South Carolina
Conditions: Ear Infection, Otitis Media
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Developing a Trauma-focused Intervention for Older Adults Living With HIV
NCT05287230
Recruiting
Investigators are adapting the LIFT and REFLECT interventions for older adults living with HIV who have been exposed to childhood sexual abuse.
Gender:
All
Ages:
Between 50 years and 85 years
Trial Updated:
12/01/2023
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Trauma, Hiv, Aging
Register for Updates
Reducing Metabolic Dysregulation in Dyads
NCT06117241
Recruiting
This study is a 6-month randomized controlled trail of diet modification designed to reduce chronic inflammation and reverse metabolic dysfunction among obese individuals with one or more polyps found at a colonoscopy screening. We also will recruit an at least overweight partner, who lives in the same household. To be eligible, participants will be apparently disease-free, obese AAs or EAs who have self-identified a partner who is at least 9 years, with whom they live and who also is at least o... Read More
Gender:
All
Ages:
Between 9 years and 55 years
Trial Updated:
10/30/2023
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Colorectal Cancer, Inflammation, Nutrition Related Cancer
Register for Updates
Mindful Walking Program for Older African Americans
NCT06085196
Recruiting
The goal of this clinical trial is to understand the beneficial role of mindful walking in sustaining cognitive health in African American older adults who have elevated risk of developing neuropsychological diseases. The main question it aims to answer is "Does a multi-session mindful walking intervention lead to promising signals of sustaining cognitive health in vulnerable AA older adults?" The researchers in this 2-arm randomized controlled trial will compare the mindful walking group with a... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
10/12/2023
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Cognitive Function, Aging Well, Behavior, Health
Register for Updates