There are currently 165 clinical trials in Columbia, South Carolina looking for participants to engage in research studies. Trials are conducted at various facilities, including University of South Carolina, Prisma Health Richland Hospital, GSK Investigational Site and Palmetto Health South Carolina Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Post-Market Study for Long-Term Effectiveness and Safety of the NTX100 for RLS
NCT06076499
Recruiting
Multi-center post-market, observational study to assess the long-term effectiveness and safety of the NTX100 TOMAC System for patients with Restless Legs Syndrome.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
09/24/2024
Locations: Bogan Sleep Consultants, LLC, Columbia, South Carolina
Conditions: Restless Legs Syndrome
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Pulse Endovascular ReperFUSION for Acute Ischemic Stroke
NCT06052969
Recruiting
Prospective, multi-center, single-arm early feasibility study enrolling a minimum of 15 subjects at up to a minimum of 3 active investigational sites in the United States. The subjects must be diagnosed with acute ischemic stroke (AIS), must be post-mechanical thrombectomy, will have had intravenous thrombolytics, and have a visible MCA, ACA or PCA occlusive clot on initial angiographic imaging. Each subject will receive the Pulse NanoMED procedure after attempted neurovascular therapy to achi... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
08/26/2024
Locations: University of South Carolina - Prisma, Columbia, South Carolina
Conditions: Acute Ischemic Stroke AIS, Cerebral Arterial Disease
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ABTECT - Maintenance
NCT05535946
Recruiting
This is a multicenter, randomized, placebo-controlled study to evaluate the long-term efficacy and safety of ABX464 50mg and 25mg administered once daily (QD) as maintenance therapy in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhi... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
08/06/2024
Locations: Columbia Digestive Health Research, Columbia, South Carolina
Conditions: Ulcerative Colitis
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Usability of the Adapted Rower for People With Spinal Cord Injury
NCT05959837
Recruiting
The goal of this clinical trial is to examine usability of a locally built adaptive rower for people with spinal cord injury using an established and tested design. The main questions it aims to answer are: 1. What exercise intensity of activity do users achieve on the rower for steady state and interval rowing plans? 2. What assistance is required for setup and usage of the adaptive rower? 3. What do users think about the ease of use and what is their satisfaction with the adaptive rower? Pa... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/02/2024
Locations: Public Health Research Center, Columbia, South Carolina
Conditions: Spinal Cord Injuries
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Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis
NCT05975983
Recruiting
The goal of this clinical trial is to learn about INS018_055 in adults with Idiopathic Pulmonary Fibrosis (IPF). The primary objective is to evaluate the safety and tolerability of INS018_055 orally administered for up to 12 weeks in adult subjects with IPF compared to placebo.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
07/25/2024
Locations: Bogan Sleep Consultants, LLC, Columbia, South Carolina
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
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ABTECT-1 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -1
NCT05507203
Recruiting
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhibitors, anti-integrin... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
07/25/2024
Locations: Columbia Digestive Health Research, Columbia, South Carolina
Conditions: Ulcerative Colitis
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Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents
NCT05893459
Recruiting
The goal of this clinical trial is to investigate how the friendship experiences of maltreated (i.e., abused and/or neglected) and non-maltreated adolescents differentially influence their risk for adverse outcomes. The main questions it aims to answer are: 1. How do the friendships of maltreated adolescents differ from those of non-maltreated adolescents? 2. Which friendship experiences influence the associations between maltreatment and ability to regulate stress, as well as future mental hea... Read More
Gender:
ALL
Ages:
Between 13 years and 17 years
Trial Updated:
07/12/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Child Maltreatment, Interpersonal Relations, Victimisation, Psychopathology, Electrocardiography
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Family-Based Prevention With Black and Latinx Children
NCT06111651
Recruiting
The main objective of this project is to test whether providing parenting support, with an added emphasis on ethnic-racial socialization and healthy lifestyle behaviors, improves the social-emotional functioning and healthy lifestyle behaviors of Black and Latinx children.
Gender:
ALL
Ages:
Between 3 years and 6 years
Trial Updated:
06/13/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Child Behavior, Health Behavior
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HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry
NCT06425848
Recruiting
The purpose of the HF2 (Hemodynamic Frontiers in Heart Failure) registry is to collect relevant patient-level demographic, clinical, laboratory, and hemodynamic data from patients implanted with pulmonary artery pressure sensor at participating centers to advance scientific knowledge about ambulatory hemodynamics monitoring and HF (Heart Failure) therapies. The data collected will be used for retrospective studies, quality improvement, identifying research cohorts, and member-initiated research.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
05/21/2024
Locations: Prisma Health, Columbia, South Carolina
Conditions: Heart Failure
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Resistance Exercise and Creatine in Colorectal Cancer
NCT06420726
Recruiting
skeletal muscle mass and function, is prevalent in up to 60% of colorectal cancer patients. This condition arises from a combination of factors such as aging, inactivity, treatment side effects, malnutrition, tumor burden, and inflammation. Given this complexity, singular interventions may not be sufficient to address sarcopenia in this group. Creatine monohydrate, a compound vital for energy during exercise, has been extensively researched and proven safe and effective across various demograph... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Colorectal Cancer
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Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
NCT00736749
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
04/10/2024
Locations: Prisma Health Richland Hospital, Columbia, South Carolina
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
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LOWER: Lomitapide Observational Worldwide Evaluation Registry
NCT02135705
Recruiting
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Gender:
ALL
Ages:
All
Trial Updated:
03/11/2024
Locations: Palmetto Health, Columbia, South Carolina
Conditions: Homozygous Familial Hypercholesterolemia
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